Conceptual Basis Research Articles

Measurements of traditional Chinese medicine health literacy regarding chronic pain: a scoping review.

Chronic pain is a prevalent health condition that imposes a significant burden on the global health system. Health literacy is a determinant of the quality of pain management which directly impacts public and individual health. However, the existing health literacy measurements have predominantly focused on medical models stemmed from Western culture and the knowledge of non-Western health models has largely been neglected. This review scopes refereed health literacy publications with regard to traditional Chinese medicine and chronic pain to explore and identify 1) the conceptual basis underlying the development of traditional Chinese medicine health literacy in this area, and 2) measurement tools used in this area and their associated psychometric qualities. Twenty-eight journal articles were assessed and the results showed that most studies' conceptual frameworks were unable to cover three key health literacy aspects defined by the World Health Organization (access, understand, and apply). Furthermore, the identified health literacy measurement tools generally lacked rigorous psychometric evaluation. Future studies should focus on exploring a comprehensive model that encompasses various health models and developing measurement tools with more culturally representative psychometric assessments.

Abstract 4143267: Bicaudal-C Homolog 1 Plays a Significant Role in Cardiac Development and Congenital Heart Defects

Background: Congenital heart defects (CHDs) are the most common birth defects globally and often require palliative surgical interventions with limited long-term effectiveness. Prenatal detection of CHDs is challenging due to the absence of heart failure signs in most fetuses. Thus, early detection methods and therapeutic drugs to correct abnormal heart development are crucial. We have discovered that the RNA-binding protein Bicaudal-C homolog 1 (Bicc1) influences normal and abnormal heart development. Bicc1 is involved in post-transcriptional regulation and interacts with RNA interference (RNAi) components. While its role in left-right patterning, kidney development, and the interaction with PKD genes ( Pkd1 and Pkd2 ) is documented, the role of Bicc1 and its expression in heart development and whether it relies on interaction with Pkd1/Pkd2 are not understood. Methods and Results: To start addressing these knowledge gaps, we used a transgenic mouse line with an in-frame fusion of Bicc1 and the LacZ reporter gene to perform β-galactosidase staining, RNAscope and immunostaining to identify the cardiac cell types expressing Bicc1 . High Bicc1 expression was observed in embryonic and neonatal hearts, particularly in the ventricles, atria, and endothelial cells of blood vessels. Expression decreased in adulthood but persisted at basal levels. We observed that Bicc1 knockout (KO) developed heterotaxy of the heart and enlarged atria. Next, to elucidate the gene and miRNA regulatory networks involved in cardiac development disrupted by the absence of Bicc1, we carried out RNA- and miRNA-seq on hearts from wild-type and Bicc1 KO embryonic hearts at different developmental stages. Several genes and miRNAs associated with ciliopathy and heterotaxy, including miR-196 , Hand1 , and Lefy2, were significantly altered in Bicc1 KO mice. Moreover, as reported for the kidney, Pkd2 mRNA expression was altered in Bicc1 KO mice, while Pkd1 expression remained unchanged. Finally, we detected changes linked to lipid metabolism and related pathways, such as members of aldehyde dehydrogenase ( Adlh1a ) and cytochrome P450 family ( Cyp5a1 ), that were altered in the absence of Bicc1 . Conclusions: Our study reveals additional role(s) for Bicc1 in heart development suggesting its involvement in regulating heart metabolism in fetuses. These findings provide a conceptual basis for future investigations into the function of Bicc1 in heart development and how its disruption contributes to CHDs.

The essence and characteristics of global value chains: theoretical aspect

The article carries out a comparative analysis of scientific approaches to understanding the essence of global value chains, as a result of which the author’s position on this issue is substantiated. It has been established that the territorial organization of international business and the international division of labor form the conceptual basis of the formation of global value chains. Special attention is paid to how processes of global economic integration contribute to constant modifications of value chains, as well as the importance of their effective management, which is a decisive factor in increasing the competitiveness of companies and countries. The article argues that participation in global value chains provides businesses and governments with significant benefits, such as access to new markets, increased production efficiency, and increased value added. At the same time, risks have been identified, in particular those related to the instability of supply chains, increased competition and dependence on global markets. Different types of global value chains and features of their management in the conditions of modern challenges of globalization are considered. Conclusions have been made regarding the prospects for the development of Ukrainian business based on the concept of global value chains, taking into account global trends and national features of the economy. The article is useful for scientists, specialists in the field of international business and economics, as well as for those who are interested in the integration of national economies into global production processes. A comparative analysis of the positions of modern scientists regarding the essence of global value chains was carried out. Reasoned author’s position on the issue of the essence of global value chains. It has been established that the territorial organization of international business, as well as the international division of labor, is the conceptual basis for the formation of global value chains. It is argued that in the conditions of strengthening integration processes in the global economy, constant modifications of global value chains take place, and their management becomes one of the important factors of competitiveness. The benefits that business units and countries receive from participating in global value chains are determined, and the associated risks are also identified. The typology of global value chains, features of their management are analyzed. Conclusions have been made regarding the prospects for domestic business development based on the concept of global value chains.

ПОДАТКОВА СИСТЕМА УКРАЇНИ ТА КРАЇН ЄВРОПЕЙСЬКОГО СОЮЗУ: ПОРІВНЯЛЬНИЙ АСПЕКТ

Introduction. The tax system is one of the main tools of economic policy, which allows to regulate financial flows, stimulate economic development and ensure the stability of public finances. Comparing the tax systems of Ukraine and the European Union countries is important for understanding the ways of integration and adaptation of the Ukrainian economy to European standards, especially considering Ukraine's intentions to join the EU. The purpose of the article. The goal of the research is to identify the peculiarities of the functioning of the tax system of Ukraine and the tax systems of the European Union and, on the basis of a comparative analysis, to identify their positive and negative characteristics. Methods. The research methodology involves the use of a comprehensive approach, which includes the analysis and systematization of sources of scientific and practical literature, regulatory and legal framework and analytical data. The research uses methods of comparative analysis to determine the advantages and disadvantages of the analyzed tax systems, a system approach to determine the conceptual basis of the functioning of the tax system of Ukraine and the EU countries, as well as a method of logical generalization to formulate conclusions. At the same time, the article uses a tabular method to visually present the research results. Results. The article defines the necessity of researching the tax systems of the countries of the European Union and the tax system of Ukraine. It was found that the level of taxation in Ukraine corresponds to the average European indicators. An analysis of rates for value added tax, personal income tax, and income tax in Ukraine and in such countries of the European Union as Germany, Spain, Italy, France, Poland and others was carried out. The analysis showed that Ukraine currently has one of the lowest tax rates for the three main taxes among the European countries under review. It has been proven that there is no ideal taxation system. The main advantages and disadvantages of the investigated tax systems are determined. Conclusions. The importance of forming an optimal taxation system in Ukraine as a key element of the socio-economic development of the country in the conditions of military aggression is proven. The main imperatives for the development of the tax system of Ukraine in the conditions of European integration processes are proposed.

Linguistic, Metalinguistic and Psychiatric Characteristics of Children with Speech Sound Disorder

Abstract: Comparing the linguistic and metalinguistic profiles in common developmental speech and language disorders is important in advancing our understanding of their clinical symptoms, as well as potentially informing the conceptual basis of novel interventions. The purpose of the present review article is summarizing linguistic, metalinguistic and psychiatric characteristics of children with speech sound disorder (SSD). Clinically and theoretically, it is important that we can understand different error pattern uses among children with SSD only and children with co-occurring SSD and language impairment (LI). Identifying differences in error pattern use will help to discovering the underlying causes of the different types of patterns. In comparison with children with SSD, children with co-occurring SSD and LI use certain patterns more frequently that suggest more global linguistic deficits. The early identification of children who are at risk for development of co-occurring SSD and LI as well as later literacy problems needs to distinguish these patterns. Identification of speech error patterns and their underlying cognitive-linguistic processing deficits will contribute to diagnosis of children at risk of co-occurring SSD and LI and reading problems. Mounting studies have reported that children with SSD, with and without language impairment have differences in phonological processing, literacy skills, and speech production patterns. Children with both speech sound and language disorders are likely to have more severe literacy problems than those with isolated speech sound disorders. In addition, this paper focuses on the comorbidity between psychiatric disorders specially attention deficit/hyperactivity disorder (ADHD) symptoms and SSD.

A Study To Assess Knowledge And Attitude Regarding Complementary And Alternative Medicine Among Community People (20-60 Years) In Selected Rural Area Of Kolar District With A View To Develop Information Booklet.

Background: Traditional Indian Systems of Medicine, including Ayurveda, Siddha, Unani, Yoga, Naturopathy, and Homoeopathy, have played a significant role in global healthcare. This study provides general information on these systems, focusing on their historical background, conceptual basis, and different disciplines studied. It aims to understand the importance and uses of these systems in evolving material medico and their future role in healthcare. Aim: The primary objective was to assess knowledge and attitude regarding complementary and alternative medicine and to find the co relation and association between knowledge and attitude. Methods: A descriptive design was used to study 75 study participants who fulfilled the inclusion criteria from a selected Rural Area of Kolar District. The instruments were prepared by the investigator to assess the knowledge and attitude related to complementary and alternative medicine. Information booklet was provided to all study participants after the data collection. Results: The current study findings show that 70% (SD 3.524) had inadequate knowledge and 68% (SD 4.534) had moderately favorable attitude towards complementary and alternative medicine. Conclusion: The findings of the study indicate that Complementary medicine is an increasing feature of healthcare practice, but considerable confusion remains still the same about what exactly it is henceforth information booklet was provided to the study participants to increase their knowledge on its importance and uses.

A Systematic Mapping of Configuration Management Activities in Software Product Line

In the software product line (SPL), configuration management (CM) is a multidimensional problem that is taking great attention in software development.  Although much research has been developed on this topic, there is no clear view of the current state of it. In this study, we used a systematic method to develop a map of configuration management across product lines to classify relevant literature. The resulting map provides an overview of this research through the identification of the main activities of the CM, the types and trends of research as well as the maturity of existing contributions. Because the CM in SPL is still in its formative stage, we believe that this work will contribute to the process of providing a more common and coherent conceptual basis for its understanding. In addition, it can help to detect important research problems and gaps.

A Review on University-Industry Collaborations from an Institutional Theory and Institutional Resilience Perspective

Institutional theory posits that organizations are in a reciprocal relationship within their environment, and in this sense, organizations are both shaped by their environment and reconstruct the existing environment with their actions. In an environment where actors mutually and reciprocally influence each other, there are substantial literature studies showing that the institutional effects may be an important factor for determining interfirm collaborations. However, the literature on institutional explanations for the establishment or non-formation of collaborations between university and industry in such environmental settings is relatively limited. In that regard, we employ institutional approach as a conceptual basis for the understanding of the processes of university- industry interactions. In our conceptual study, we aim to extend the institutional perspective by focusing on interorganizational collaborations in terms of university industry collective interactions where the actors mutually concerned with the normative, coercive, and mimetic pressures. We introduce the concept of institutional resilience to Triple Helix Model to propose some new research avenues.

Genetic and phenotypic changes to Venezuelan equine encephalitis virus following treatment with β-D-N4-hydroxycytidine, an RNA mutagen

The high mutation rate of RNA viruses provides viral populations with the ability to adapt to new environments but also makes them vulnerable to extinction due to the deleterious effects of mutations, which is the conceptual basis for the antiviral activity of RNA mutagens. However, there are still gaps in the quantitative understanding of the dynamics between the mutations induced by an RNA mutagen and its effects on viral fitness. To address this, we used Venezuelan Equine Encephalitis Virus (VEEV) and the potent RNA mutagen β-d-N4-hydroxycytidine (NHC) as a model to analyze virus replication competency and mutation frequency following treatment in the total and replication-competent viral populations separately. We found that NHC induced transition mutations in a concentration dependent manner in the total population, while the replication-competent population maintained itself within an increased, yet narrow, mutation spectrum. The incorporation of NHC mainly happened during the positive sense RNA synthesis of VEEV. A growth kinetic analysis of VEEV population treated with NHC pointed to a lower but more diverse distribution in mutational fitness, demonstrating that NHC-induced mutations negatively and broadly affect the fitness of the virus. Together, our study provides mechanistic insight into how RNA mutagens affect viral population landscape and the potential of RNA mutagens as an antiviral strategy for alphaviruses.

Therapist responsiveness in psychotherapy: Introduction to the special issue

Therapist responsiveness denotes that therapists provide therapeutic interventions within an emerging context of client manifestations and moment-by-moment internal and external changes. So far, psychotherapy research on explaining how therapy works falls short of operationalizing the sequence of events constituted by therapist responsiveness. The present special section of Psychotherapy Research addresses this conceptual and methodological gap and proposes six original contributions, using several validated assessment protocols, both from a quantitative and qualitative viewpoint, to study therapist responsiveness in psychotherapy. It aims at providing a rigorous conceptual and methodological basis for studying a core principle of change in psychotherapy for the future.

Assessing the Influence of Economic Factors on the Dynamics of Exports of Russian Oil and Petroleum Products Based on the Use of a Combination of PEST and SWOT Analysis Methods

The presented work is part of a series of articles devoted to assessing the influence of external factors on the dynamics of Russian exports. In this and subsequent related works, the authors proposed to consider the external environment, which had a significant impact on the dynamics of Russian exports and the relative diffi culty of revising its structure, the basis of commodity exports of which in value terms are hydrocarbon energy carriers. This work represents a conceptual basis for the use of instrumental methods for assessing the influence of external factors, in this case, economic ones, on the integral and sectoral indicators of Russian exports and, in particular, on the export of hydrocarbon energy resources. In the second part of this article, it is proposed to use a set of environmental analysis methods, the basis of which was the previously successfully used mechanism for combining the methods of PESTEL and SWOT analysis, which will make it possible, based on the use of scores, to describe the cumulative influence of external factors on the dynamics of the main industries of Russian exports. The novelty of the presented approach lies in the absence of a methodology for a comprehensive assessment of the influence of external factors on the dynamics of Russian exports using the selected tools, which seems useful and timely in light of the emergence of new political and economic factors that have a significant impact on Russian foreign trade in general and on the dynamics of the carbohydrate energy market , in particular. The parameters for assessing external factors proposed by the authors were chosen by the author independently, taking into account the modern realities of the development of the world economy, which can also represent a separate point of novelty of the research conducted or be part of one of the existing points of novelty of the presented work. The merit of the authors of this work lies in the fact that this work proposed their own vision of a comprehensive assessment of the influence of external factors on the dynamics of the country’s exports.

Environmentally sound geotechnologies for leaching metals from polymetallic ore processing wastes and wastewater

Global challenges (increased consumption of georesources, climatic changes, limited reserves) increase the relevance of the problems of growing waste accumulation and environmentally-sound modernization of mineral extraction. In this regard, the existing approaches to the design of geotechnologies for metal mining need to be improved based on a concept of so-called circulation waste management and ecologization of technological processes. The paper is devoted to the issue of formation of conceptual bases and directions of ecologization of geotechnologies at leaching metals from polymetallic ore processing wastes and wastewater. The study presents recommendations for improving in-situ leaching of ores in blocks, allowing to determine the optimal conditions for increasing the completeness of subsoil use and reducing environmental damage. It was revealed that at metal extraction with solution circulation through brine chambers the content of Na, Cl, SO4 and Ca ions in dialysate was low, while without circulation through brine, it significantly exceeded corresponding MPCs. This proves the fundamental feasibility of controlling natural leaching processes by enhancing the oxidizing potential of natural solvents through the addition of industrial oxidizing agents. It was found that increasing the duration of agitation leaching (both with and without mechanoactivation) leads to a uniform expansion of the local maximums of Pb yield from the pulp when the minimum NaCl concentration decreases from 11–12 to 7% at H2SO4 concentration of 0.6%. One of key results of the study is justifying the expansion of the use of disintegrators to realize targeted activation of tailings. The practical significance of the obtained results lies in the proved feasibility of optimizing the flow sheet of electrochemical extraction of metals from wastewater on the basis of the obtained regularities of the use of brine circulation through brine chambers. In addition, the totality of the obtained results of using a disintegrator for reextraction of lead from geomaterials will allow developing a methodology for calculating the parameters of mechanoactivation action to increase the degree of metal recovery from the tailings of North Ossetia-Alania’s (Zgidskoe, Sadonskoe, Arkhonskoe deposits) polymetallic ores beneficiation. The most promising way for further research is to substantiate methods of using underground space for complete removal of wastes (wastewater and tailings) after their multistage treatment.

Symbolism of Fair Plots in Genre Painting of Peter Bruegel the Elder

The purpose of the article is to analyse the use of fair plots in the works of Pieter Bruegel the Elder, to reveal their symbolism in presenting the panorama of contemporary society. The methodology of the work consists in the application of such scientific research methods as: historical – when examining the artist's paintings in the context of the historical era in which he lived and worked; analytical, which made it possible to single out works with a fair plot from the artist's creative heritage; synthetic, thanks to which observations acquired through analysis became the basis for formulating a general conclusion; comparative art analysis is applied to reveal the specifics of Bruegel's genre painting depicting fairs. The scientific novelty of the work consists in the actualisation of the study of the work of the Dutch artist Pieter Bruegel the Elder, which presents fair scenes that enabled the artist to comprehensively present the motley society of that time in an artistic manner specific to the artist. Conclusions. Pieter Bruegel the Elder's paintings are filled with hidden meaning, the depicted events are connected with history, contemporary politics, reflect the thoughts and ideas of the author, that is, they are symbolic. Bruegel is one of the founders of Dutch genre painting – a direction of fine art in which the painter's attention is devoted to ordinary, everyday, multifaceted life, in the centre of which are people. Using fair plots, the artist discovered new themes and images for art. With the help of fair scenes, Bruegel depicted a generalised picture of the life of society, recorded the traditions and daily life of his contemporaries. The artist's paintings are historical documents that make it possible to track the activities of his compatriots. Pieter Bruegel the Elder, thanks to his creative, innovative abilities, a keen sense of the urgent problems of his people, acquired many followers who copied his paintings, in particular from fair themes, developed his plots. For the artist, the fair plots became a conceptual basis that contributed to the comprehensive artistic reproduction of the national characteristics of the Dutch people, as well as a means of figuratively embodying his creative ideas. The fair theme of the paintings allowed the artist to depict the peculiarities of the modern multifaceted life and activities of the Dutch people, to demonstrate the transformational processes that took place among different layers of the population, to present his own vision of the panorama of the contemporary society, the miniature format of which was the fairs.

Psychological Determinants of Health Behavior.

This review provides a critical overview of current evidence on psychological health behavior determinants and its value in informing intervention and future determinants research. The review begins with work labeling and classifying the myriads of determinants available in the extant research to arrive at core groups of determinants. Next, the conceptual bases of these determinant groups are identified, and the weight of the evidence for their purported effects on health behavior, including belief-based determinants (e.g., outcome expectancies, capacity beliefs), determinants representing self-regulatory capacity (e.g., planning, action control) and nonconscious processes (e.g., habit, implicit cognition), and dispositional determinants (e.g., personality, regulatory control), is critically evaluated. The review also focuses on the theory-based mechanisms underpinning determinant effects and moderating conditions that magnify or diminish them. Finally, the review recommends a shift away from research on determinants as correlates, outlines how determinants can inform intervention development and mechanisms of action tests, suggests alternatives to predominant individualist approaches, and proposes future research directions.

Psychoeducation of higher education seekers with using of the resource-oriented model of stress resiliency in war conditions

The article presents the study results of resiliency modalities and the content of psychoeducational measures for higher education seekers in war conditions. The purpose of the study was to increase the effectiveness and to balance resiliency modalities use by higher education seekers in war conditions while using psycho-educational measures. 174 seekers of higher education were examined, including 144 students of the 4th-6th year of the medical faculty and the faculty of medicine and pharmacy of the Dnipro State Medical University, specializing in 222 «Medicine» (main group) and 30 students of the 4th-5th year of the metallurgical and electro-metallurgical faculties of the Ukrainian State University of Science and Technology (comparison group). A psy­chodiagnostic method using the resource-oriented model of stress resiliency "BASIC Ph" was employed. The first stage involved a statistical analysis of resiliency modalities and their average scores in both groups. In all participants of the main group, it was found that the highest average score was registered in the resiliency modality “Cognitive strategy”. The lowest score was observed for the “Social support” modality. In all participants of the comparison group, it was found that the “Cognitive strategy” modality, as in the main group, had a clear advantage over other modalities, and the lowest score was already observed for the “Emotions” modality. These results formed the basis for creating psychoeducational measures for stress resiliency among higher education seekers in wartime. Psychoeducation for higher education seekers was conducted from September to November 2023, including lectures and individual conversations upon request. The «BASIC Ph» model of stress resiliency was utilized as a framework for determining optimal human resource utilization during crises, with six modalities forming individual style of resiliency. It is crucial to identify dominant modalities and develop those that are less effective. The identified stress resiliency modalities provided a conceptual basis for developing of psychoeducational measures to enhance their effective and balanced use in war situations among higher education seekers. During psychoeducational work with higher education seekers, their resiliency models were analyzed, interpreted, and balanced. Study results should be taken into account in psychological support efforts for higher education seekers in war and post-war time.

Absolute mass spectrometry: A theoretical analytical technique for quantification

Mass spectrometry (MS) is an analytical chemistry technique that requires calibration with standards in order to quantify an analyte in a sample. In many cases the reference standards may be difficult to obtain or unavailable. In fact, when MS is applied to study reactions that yield multiple products, their quantification requires several standards and involves time-consuming and tedious calibration procedures. In other applications like Mass Spectrometry Imaging (MSI), quantification becomes even more tedious when on-tissue standards or mimetic tissue models are required. In this work, we introduce a new measurement technique that we called the Absolute Mass Spectrometry (AbMS), which allows the absolute quantification of an analyte without the need for calibration standards. This technique is based on the “Influence Method” developed in 2015 for nuclear measurements which, when applied to MS, produces this improvement for analyte quantification. Two possible applications of this technique are presented. One is the conceptual development of a mass spectrometer with electronic ionization that does not require calibration to determine the amount of analyte. The other one describes how to apply this technique in a mass spectrometer with other ionization sources like MALDI, DESI, and SIMS, which are used in MSI. AbMS technique uses the conceptual basis of Influence Method and two consecutive measurements to estimate the amount of analyte. Specifically, AbMS can be directly employed as an absolute method for quantification in MSI. Therefore, it constitutes an attractive complement for research applications in pharmaceutical and health sciences.

Predicting teacher voice behaviour: The influence of distributed leadership, psychological empowerment and power distance orientation in Kuwait

Teacher voice behaviour is a significant instrument for developing positive change, better decision-making and raised school efficacy at an educational institution, with a principal's leadership facilitating this mechanism. The purpose of this study is to investigate how and under what conditions a school principal's implementation of distributed leadership affects teacher voice behaviour within their school. Data from 1024 teachers across 36 public schools in Kuwait was examined using regression analysis and bootstrapping methods. This research examined a moderated mediation model of distributed leadership effects upon teacher voice behaviour, with teacher psychological empowerment included as the mediator and power distance orientation as the moderator. Results revealed a partial mediation model and found that distributed leadership had significant direct and indirect effects upon teacher voice behaviour. Power distance orientation negatively moderated the relationship between psychological empowerment and teacher voice behaviour. This study contributes to existing distributed leadership literature by identifying psychological empowerment as an additional mediator, and power distance orientation as a boundary condition, in the relationship between distributed leadership and teacher voice behaviour. This study's findings could provide the conceptual basis for interventions designed to promote teacher voice behavior.

Restitution of African Cultural Heritage: Revisiting Natural Law Concepts of Statehood and Property in the Context of Colonial Spoliation

Abstract In the late nineteenth century, Western Powers launched military campaigns in sub-Saharan Africa resulting in the colonization of vast territories and the spoliation of cultural property. To justify the conquest, they asserted the supremacy of Western culture and disregarded principles of international law in their dealings with African states, communities, and individuals. This article examines colonialist legal justifications such as the denial of statehood of pre-colonial sub-Saharan African societies, the notion that conquest and spoliation were justifiable, and the belief that African legal systems lacked concepts of property. The article details why these arguments contradict well-established nineteenth-century legal principles, particularly state sovereignty and private property, which together form the conceptual basis for the prohibition of spoliation. The universal nature of those principles allows for the nondiscriminatory application and interpretation of historical law and consequently the protection of African pre-colonial states and private as well as public cultural property.

Quantitative Chemical Sensing Using Genetically Engineered Bacterial Bioreporters

We present a generic quantitative chemical sensing methodology for assessing the concentration of a target material (TM) in an aqueous solution by using bioluminescent microbial bioreporters as the core sensing elements. Such bioreporters, genetically engineered to respond to the presence of a TM in their microenvironment by emitting bioluminescence, have previously been mostly designed to report the presence or absence of the TM in the sample. We extend this methodology to also assess the TM concentration, by exploiting the dose-dependency of the TM-induced luminescence. To overcome luminescence intensity variations due to bacterial batch differences and the ambient temperature, simultaneous measurements were carried out on sample solutions containing known concentrations of the TM. A “standard ratio” parameter, defined as the ratio between the two measurements, is shown to be independent of the bacterial batch and the temperature, and hence provides the conceptual basis for a generic quantitative chemical sensing methodology. Assessment of 2,4-dinitrotoluene (DNT) concentration in solutions is demonstrated with an accuracy of 2.5% over a wide dynamic range.

Методологические проблемы осмысления связи права и морали

In the article, questions of the methodology of the study of the connection between law and morality appear as a search for its conceptual basis, which would make it possible not to discard, but only to overcome the shortcomings of the dominant stereotyped perception of this connection, formed within the framework of classical and modern German philosophy of law. The essence of the author’s position is that the question of the nature and essence of the connection between law and morality is in the field of comparison of legal and moral consciousness.