Concept Of Quality Control Research Articles

MANAJEMEN PENGENDALIAN MUTU LPD AL BAHJAH CIREBON

This study aims to understand the concept of quality control in Islamic boarding schools, the implementation of quality control and its implications for Al-Bahjah Islamic boarding school. This research used a qualitative research method with a case study approach. Data collection was conducted by in-depth interviews, observation and documentation. The research informants were the Head of the Foundation, Head of the Boarding School, Head of Tarbiyah Division and several alumni of Al-Bahjah Boarding School. Data were analyzed by condensation, display, and verification analysis. Then checking the validity of the data using data source triangulation. In this study, researchers found several research results, first, the planning of the quality of education at Al-Bahjah Islamic Boarding School is fast but directed. Implementation of the quality of education at Al-Bahjah Islamic Boarding School from planning through: Monthly to annual meetings to determine the RAB and quality lesson plans during the KBM process, revise and evaluate to find out what factors are the supporters and obstacles in the previous year, provide solutions or input in an effort to improve quality for the coming year, and there is control from the institution in carrying out the quality of education. The high interest of the community in Al-Bahjah pesantren is an implication of good pesantren management, proselytizing by the human resources of Al-Bahjah pesantren to the community, and teachers who are qualified in their fields who are brought in from abroad.

Study on The Adoption of Historical Record and Chain of Custody By Brazilian Judicial Experts From the Collection to the Disposal of Evidence: A Survey Questionnaire

Objective: The aim of this study is to analyze the practices and protocols of the chain of custody adopted by forensic experts in Brazil, with the intent of evaluating the effectiveness and compliance of these procedures in the evidence production process. Theoretical Framework: This research is based on theories of forensic computing and the importance of evidence preservation. It highlights concepts of quality control and standardized practices in the chain of custody, providing a foundation for understanding best practices and relevant protocols. Method: The methodology employed involves administering a specific questionnaire to a group of forensic experts across Brazil. Data was collected to gather information on chain of custody procedures, including collection, acquisition, examination, analysis, transfer, and disposal of evidence. The study aims to measure the adoption and application of standardized practices by these professionals. Results and Discussion: Results revealed significant variations in the adoption of chain of custody practices among forensic experts. The discussion contextualizes these variations in relation to established theories and practices, identifying gaps and weaknesses in protocols and suggesting areas for improvement. Implications of the Research: The implications of this research include potential improvements in evidence preservation practices and the need for greater adherence to standardized protocols, impacting the reliability and credibility of evidence in judicial processes. Originality/Value: This study contributes to the literature by identifying deficiencies in current practices and suggesting directions for enhancement. The relevance is underscored by the need to improve evidence quality and ensure the integrity of judicial processes.

Targeting lysosomal quality control as a therapeutic strategy against aging and diseases.

Previously, lysosomes were primarily referred to as the digestive organelles and recycling centers within cells. Recent discoveries have expanded the lysosomal functional scope and revealed their critical roles in nutrient sensing, epigenetic regulation, plasma membrane repair, lipid transport, ion homeostasis, and cellular stress response. Lysosomal dysfunction is also found to be associated with aging and several diseases. Therefore, function of macroautophagy, a lysosome-dependent intracellular degradation system, has been identified as one of the updated twelve hallmarks of aging. In this review, we begin by introducing the concept of lysosomal quality control (LQC), which is a cellular machinery that maintains the number, morphology, and function of lysosomes through different processes such as lysosomal biogenesis, reformation, fission, fusion, turnover, lysophagy, exocytosis, and membrane permeabilization and repair. Next, we summarize the results from studies reporting the association between LQC dysregulation and aging/various disorders. Subsequently, we explore the emerging therapeutic strategies that target distinct aspects of LQC for treating diseases and combatting aging. Lastly, we underscore the existing knowledge gap and propose potential avenues for future research.

Role of mitochondria in doxorubicin-mediated cardiotoxicity: From molecular mechanisms to therapeutic strategies.

This comprehensive review delves into the pivotal role of mitochondria in doxorubicin-induced cardiotoxicity, a significant complication limiting the clinical use of this potent anthracycline chemotherapeutic agent. Doxorubicin, while effective against various malignancies, is associated with dose-dependent cardiotoxicity, potentially leading to irreversible cardiac damage. The review meticulously dissects the molecular mechanisms underpinning this cardiotoxicity, particularly focusing on mitochondrial dysfunction, a central player in this adverse effect. Central to the discussion is the concept of mitochondrial quality control, including mitochondrial dynamics (fusion/fission balance) and mitophagy. The review presents evidence linking aberrations in these processes to cardiotoxicity in doxorubicin-treated patients. It elucidates how doxorubicin disrupts mitochondrial dynamics, leading to an imbalance between mitochondrial fission and fusion, and impairs mitophagy, culminating in the accumulation of dysfunctional mitochondria and subsequent cardiac cell damage. Furthermore, the review explores emerging therapeutic strategies targeting mitochondrial dysfunction. It highlights the potential of modulating mitochondrial dynamics and enhancing mitophagy to mitigate doxorubicin-induced cardiac damage. These strategies include pharmacological interventions with mitochondrial fission inhibitors, fusion promoters, and agents that modulate mitophagy. The review underscores the promising results from preclinical studies while advocating for more extensive clinical trials to validate these approaches in human patients. In conclusion, this review offers valuable insights into the intricate relationship between mitochondrial dysfunction and doxorubicin-mediated cardiotoxicity. It underscores the need for continued research into targeted mitochondrial therapies as a means to improve the cardiac safety profile of doxorubicin, thereby enhancing the overall treatment outcomes for cancer patients.

On the part that NMR should play in mass spectrometry metabolomics in natural products studies

The field of metabolomics has witnessed remarkable growth in the context of natural products studies, with Mass Spectrometry (MS) being the predominant analytical tool for data acquisition. However, MS has inherent limitations when it comes to the structural elucidation of key metabolites, which can hinder comprehensive compound identification. This review paper discusses the integration of Nuclear Magnetic Resonance (NMR) spectroscopy as a complementary technique to address these limitations. We explore the concept of Quality Control (QC) samples, emphasizing their potential use for in-depth compound annotation and identification. Additionally, we discuss NMR’s advantages, limitations, and strategies to enhance sensitivity. We present examples where MS alone falls short in delivering accurate compound identification and introduce various tools for NMR compound identification in complex mixtures and the integration of MS and NMR data. Finally, we delve into the concept of DBsimilarity to broaden the chemical space understanding, aiding in compound annotation and the creation of compound lists for specific sample analyses.

Functional compounds rapid screening strategy for health food function-formula-component integrated quality control by syndrome correlation-network analysis

For quality control improvement of medicine and food homology (MFH) health food, the concept of functional quality control and rapid screening strategy of functional compounds were proposed based on the dual identity characteristics. Taking Wuweisanqi Capsule as the research object, firstly, a modified method “syndrome correlation-network analysis” based on network pharmacology was used for analysis. Functions related targets were collected from common medical databases, while the clustering algorithm was used to extract the information of clinical records related to daily health care from traditional Chinese medicine (TCM) database to obtain the targets. The bioactive compounds and related targets were retrieved from the TCM Systems Pharmacology Database and Analysis Platform around the five materials included in formula. Protein-protein interaction (PPI) network and pathway enrichment analysis were performed on the intersection targets. According to the constructed formula material-compound-target-pathway network, the potential functional compounds were preliminarily identified. Secondly, key targets and compounds were analyzed by molecular docking to further screen functional compounds. Finally, combined with references, the screening and establishing determination methods of functional compounds containing total saponins, astragaloside IV, puerarin and schisandrin were finished. The rapid screening strategy adequately utilizes the advantage of TCM background for MFH health food and the effective extracting ability of massive data by the algorithm. It links three aspects of health food functions, formula materials and functional compounds, providing an efficient solution for the realization of function-formula-component integrated functional quality control, which has great application potential in health food industry.

Application of a concept for ML-driven closed-loop quality control in laser beam welding

Laser beam welding is valued for the capability of contactless welding. Despite significant technological improvements to achieve stable processes and the required quality standards, quality determination is often done destructively and offline, with unavoidable expenses. Inline approaches address this problem by using and processing collected machine and sensor data to enable indirect conclusions about the welding quality in the process. This paper presents an inline approach that merges a set of complementary sensor signals to enable the prediction of weld quality by machine learning algorithms, paving the way for closed-loop quality control.

Role of mitochondria in doxorubicin-mediated cardiotoxicity: from molecular mechanisms to therapeutic strategies.

This comprehensive review delves into the pivotal role of mitochondria in doxorubicin-induced cardiotoxicity, a significant complication limiting the clinical use of this potent anthracycline chemotherapeutic agent. Doxorubicin, while effective against various malignancies, is associated with dose-dependent cardiotoxicity, potentially leading to irreversible cardiac damage. The review meticulously dissects the molecular mechanisms underpinning this cardiotoxicity, particularly focusing on mitochondrial dysfunction, a central player in this adverse effect. Central to the discussion is the concept of mitochondrial quality control (MQC), including mitochondrial dynamics (fusion/fission balance) and mitophagy. The review presents evidence linking aberrations in these processes to cardiotoxicity in doxorubicin-treated patients. It elucidates how doxorubicin disrupts mitochondrial dynamics, leading to an imbalance between mitochondrial fission and fusion, and impairs mitophagy, culminating in the accumulation of dysfunctional mitochondria and subsequent cardiac cell damage. Furthermore, the review explores emerging therapeutic strategies targeting mitochondrial dysfunction. It highlights the potential of modulating mitochondrial dynamics and enhancing mitophagy to mitigate doxorubicin-induced cardiac damage. These strategies include pharmacological interventions with mitochondrial fission inhibitors, fusion promoters, and agents that modulate mitophagy. The review underscores the promising results from preclinical studies while advocating for more extensive clinical trials to validate these approaches in human patients. In conclusion, this review offers valuable insights into the intricate relationship between mitochondrial dysfunction and doxorubicin-mediated cardiotoxicity. It underscores the need for continued research into targeted mitochondrial therapies as a means to improve the cardiac safety profile of doxorubicin, thereby enhancing the overall treatment outcomes for cancer patients.

STUDY OF THE EFFICIENCY AND COMPARATIVE ANALYSIS OF THE APPLICATION OF TECHNIQUES FOR EVALUATING THE QUALITY OF PHYTOPHAGES AND ENTOMOPHAGES AT DIFFERENT STAGES OF ONTOGENESIS

The concept of quality control of insect crops is proposed, which is based on a targeted approach based on the goal and objectives of the implementation of a certain breeding program and is divided into two main directions: control of phytophage production, control of entomophage production. Quality control methods are based on the general biological rule of dependence between the intensity of insect taxis and the overall viability of biomaterial. The effectiveness of methods for assessing the quality of phytophages (on the example of the mother cultures of the grain moth Sitotroga cerealella, the wax moth Galleria mellonella) and entomophages (laboratory and natural populations of P. bioculatus.) of the Center for Mother Cultures of Insects Engineering and Technological Institute “Biotekhnica” of the National Academy of Sciences (ETI “Biotekhnica”) at different stages of ontogenesis was investigated using the indicator the intensity of taxis. As a result of research conducted on the culture of phytophagous, grain moth, a significant difference with the control was established in the indicators of viability of eggs, larvae, pupae and adults: 25; 6; 33 and 11%, respectively. Studies conducted with another phytophagous representative – the wax firefly – also showed positive results (16; 17; 16; 11%, respectively). The obtained (as a result of preliminary quality control) and selection culture had significantly higher viability indicators at all stages of ontogenesis. It was established that the intensity of chemotaxis of larvae of the 1st age of entomophages directly correlates with the indicator of viability of the insect culture. When selecting the starting material for successful culture, it is possible to select by chemotaxis of the larvae after rebirth from the egg. Thus, viability when selecting for Colorado beetle eggs significantly (p<0.01) exceeds this indicator in other selection options – Colorado beetle larvae and wax firefly larvae: 82; 59; 73% respectively. When working with an artificial population of P. bioculatus, on wax moth larvae, the highest intensity of taxis was noted in the variant with wax moth larvae compared to Colorado beetle eggs and Colorado beetle larvae – 37; 34; 29% respectively. This indicates a shift in the number of the population in the direction of individuals that successfully feed on unnatural food. Their viability was significantly higher than the viability in other variants of the study with an artificial population – 78; 71; 68% respectively. The proposed method of selection of starting material for cultivation of P. bioculatus allows differentiation of individuals for further effective reproduction, and the use of such biomaterial in programs of biological protection of plants from pests. A comparative analysis of methods for assessing the quality of phytophagous and entomophagous cultures at different stages of ontogenesis was carried out using the indicator of the overall viability of insect populations. It is an integrated indicator that takes into account the viability of the population at all stages of its development. All tested objects of the study showed that control and improvement of culture quality by the proposed method lead to an increase in the viability of biomaterial by 18.71; 18.56 and 8.86%, respectively (egg, larva, pupa).

STATISTICAL PROCESS CONTROL AS A TOOL FOR QUALITY IMPROVEMENT: A CASE STUDY IN DENIM PANT PRODUCTION

In this study, after defining the concepts of quality and quality control, the concept of statistical process control tools is examined. As a result of the data obtained from denim pants produced by a textile company operating in the ready-to-wear sector, defects were analyzed using statistical process control techniques. In this study, flowchart, control charts, pareto analysis, p-control diagram, cause-effect diagram, and grouping techniques were used. With the use of basic statistical process control tools, the most recurring defects were, and these defects were divided into subheadings for more detailed analysis. In this way, it was tried to prevent the repetition of defects by going down to the root causes of the detected defects. The causes of possible defects that may occur during production and solution suggestions were categorized. By going down to the basic causes of the detected defects and categorized them, defects were prevented by presenting and implementing solution suggestions. It is expected that the study with this different perspective will be an example of the sector and related fields as an alternative method. The aim of this study is to examine quality control practices in the garment industry, contribute to statistical control methods and problem-solving procedures, produce suggestions for problem-solving approaches, and disseminate improvement studies.

Desarrollo de una aplicación informática de ayuda al soporte nutricional especializado integrado en la historia clínica electrónica

ObjectivesTo develop an integrated computer software application for specialized nutritional support, integrated in the electronic clinical record, which detects automatically and early those undernourished patients or at risk of developing undernourishment, determining points of opportunity for improvement and evaluation of the results. MethodsThe quality standards published by the Nutrition Work Group of the Spanish Society of Hospital Pharmacy (SEFH) and the recommendations by the Pharmacy Group of the Spanish Society of Parenteral and Enteral Nutrition (SENPE) have been taken into account. According to these quality standards, the nutritional support has to include the following healthcare stages or sub-processes: nutritional screening, nutritional assessment, plan for nutritional care, prescription, preparation and administration. ResultsThis software allows to conduct, in an automated way, a specific nutritional assessment for those patients with nutritional risk, implementing, if necessary, a nutritional treatment plan, conducting follow-up and traceability of outcomes derived from the implementation of improvement actions, and quantifying to what extent our practice is close to the established standard. ConclusionsThis software allows to standardize the specialized nutritional support from a multidisciplinary point of view, introducing the concept of quality control per processes, and including patient as the main customer.

Quality Assurance in Digital Forensic Investigations: Optimal Strategies and Emerging Innovations

Digital forensic investigations are critical in modern law enforcement, cybersecurity, and legal proceedings. Ensuring digital evidence’s accuracy, integrity, and reliability is paramount in these contexts. This review article explores the challenges and best practices associated with quality control in digital forensic investigations and the emerging technologies that are reshaping the field. The article begins by discussing the foundational concepts of quality control in digital forensics, emphasizing the need for standardized procedures, documentation, and validation techniques. It delves into the potential sources of errors and bias that can arise during the acquisition, preservation, analysis, and presentation of digital evidence. It highlights the importance of continuous monitoring and review to mitigate these risks. The review article further examines the evolving landscape of digital forensic tools and technologies advancing quality control efforts. It covers advancements in data acquisition methods, including live forensics and memory analysis, and discusses the role of artificial intelligence and machine learning in automating quality control processes. The integration of Blockchain and cryptographic techniques for ensuring the integrity of digital evidence is also explored. In addition, the article addresses the challenges and opportunities presented by cloud computing, IoT devices, and the proliferation of digital data sources. It emphasizes adaptability and agility in quality control approaches to accommodate the changing digital landscape. Through a comprehensive analysis of established practices and emerging technologies, this review article offers practitioners, researchers, and policymakers’ insights into enhancing the reliability and trustworthiness of digital forensic investigations. By adopting robust quality control measures and embracing innovative technologies, the digital forensics community can ensure its findings hold up to scrutiny in the courtroom and beyond.

Application of Quality Control and Risk Management in Maintaining Product Quality with A Risk Breakdown Structure Approach

This research was conducted in a company that operates in the printing or graphics sector. The concept of quality control is the most critical part because newspapers or printed media are products with the fastest production process. PT carries out the quality control process. PT XYZ to lower the failed results on the paper. Quality control measurements use the P chart method. Results of quality control measurements at PT. XYZ is outside the control limits, and that is not normal, so corrective action is needed, especially the number of failed newspapers. On average, newspapers failed from January to May, reaching 8.24% of the total newspapers produced. Events that cause failure in newspapers are analyzed through risk management. Risk management measurements use the Risk Breakdown Structure (RBS) and Fault Tree Analysis (FTA) methods. Risk management results show that five risks cause newspaper failure, namely scattered ink, slanted fonts, blurred images, dirty images, and thick fonts.

Experimental Epizotology of Low-Virulent Variants of African Swine Fever Virus

African swine fever (ASF) remains an urgent problem of pig farming in Ukraine, the solution of which is possible only on the basis of deep scientific knowledge about the specific driving forces of the epizootic in its specific nozoareal. This is necessary in order to target anti-epizootic measures on the most vulnerable link of the epizootic chain in a specific nozoareal. The aim of the work was to develop a low-budget methodological base for experimental epizootology of low-virulent ASFV variants in Ukraine, in particular, to study the mechanisms of the formation of enzootic areas, quality control of anti-epizootic measures, and evaluation of the effectiveness of the antiviral drugs against them in Ukraine. Methods. Experimental and epizootological studies in the adaptation of suckling piglets to keeping in the biosecurity-level BSL-3 for laboratory animals (Patent UA No. 133248 dated 03/25/2019) were conducted at the laboratory base of the Odesa branch of NSC «IECVM». All procedures with infectious active biological materials in the current order were carried out in the BSL-3 module, built and certified with the assistance of the US Government in UAPRI (Odesa). The ASF agent strain «IECVM/Ternopil/2017» (infectious activity 4.0—7.5lg HAdU50/cm 3) circulating in the Ternopil region in 2017—2020 was used as a test virus. The presence of low-virulence variants of the ASFV pathogen in the studied samples was determined by a bioassay on suckling piglets, followed by three consecutive passages on a stable Vero line of the baby green monkey kidney cells. The isolated ASF virus was identified according to the methods and reagents recommended by the OIE Manual. Results. Intermittent passages «by the founder’s method» of dilutions 10-1 and 10-2 of the ASF virus strain «IECVM/Ternopil/2017» on piglets (n=20) and the culture of porcine alveolar macrophages («ASFVPAM») allowed us to identify highly-, moderately-, and low-virulent variants/clones in its composition. Verifi cation by bioassay on suckling piglets (n=5) of low-virulent clones of the agent, which were stabilized in Vero cell culture («ASFVVero»), showed that after intraperitoneal infection at a dose of 4.25 lgHAdU50/cm 3, they are capable of causing only a non-lethal (within 2 weeks) viral infection with a maximum daily rectal temperature of 39.4±0.22 °C and duration of fever on average 1.6±0.14 days (5 of 5 piglets). Clones with greater virulence («ASFVPAM») under similar conditions were able to cause a lethal infection with a maximum temperature of 40.7±0.37°C and duration of fever on average 3.9±0.27 days (17 of 20 piglets). Low-virulent clones were revealed by direct immunofluorescence in pulmonary and spleen smears of clinically healthy piglets on days 14 and 17 post-infection (p.i.); their antigens were visualized in Vero cells by indirect immunoperoxidase method after 48 h p.i. at dose about 0.01 lg HAdU50/cm 3. They caused «crumbly» hemadsorption of infected Vero cells and their virions had typical for Asfarvirus view and size (210—220 nm). The obtained data served as the basis for analysis of the mechanism of rooting ASF agents in West Podillia enzootic foci, as well as for implication of the concept of low-budget quality control of anti-epizootic measures and evaluation of antiviral drugs’ activities against ASF. Conclusions. Low-cost operational procedures have been developed that allow one to use a vivarium of laboratory animals for ASF bioassay and meet principal requirements for science-based research in important aspects of experimental ASF epizootology. With their help, confirmation of the heterogeneity of the population of the ASF virus circulating in endemic foci of the Ukrainian Western Podillia was obtained (p<0.05, n=25)><0.05, n=25). The developed methodological approach is suitable for the study of fundamental issues of ASF epizootology, as well as for the quality control of anti-epizootic measures against ASF. In particular, it is advisable to use it to improve the biosecurity of agricultural export programs in Ukraine, a country that is disadvantaged by ASF.

A Quality Control Improvement Model That Takes into Account the Sustainability Concept and KPIs

Nowadays, in addition to quality aspects, social and environmental issues are also a source of competitive advantage, as a result of changing socio-economic conditions and observed trends. The purpose of the study was to create a model for improving quality control in line with the concept of sustainable development. The model captures the microfoundational approach, and allows identifying quality capability with the idea of sustainable development. The proposed method is based on analyses of the characteristic parameters of methods for detecting aluminum casting nonconformities using automated or semi-automated nondestructive methods. The interdisciplinary approach takes into account indicators from the leading areas of sustainable development (economic, environmental and social dimensions) to determine the gradation of detection methods. Verification of the model confirmed its usefulness in foundry companies. As a result, a ranking of the total efficiency of the analyzed detection methods used in the quality control of the studied product was obtained. This enabled the development of energy, emission and cost optimization of the inspection process while maintaining the expected level of quality. Further research directions will concern the expansion of the model with additional key indicators related to the concept of pure quality control and automation of the implementation of analysis.

On-line quality control and tool wear evaluation in trimming process by data analytics techniques

Sheet metal is an extremely common form of use in broad engineering sectors and represents the main consumption of steel and aluminum in Europe. All production processes where sheet metal is used require cutting operations. Therefore, it is an extremely relevant procedure, common and of great economic importance in material-intensive sectors such as automotive, construction and engineering. In a competitive environment where the demand for quality increases continuously and using harder to process high-performance materials, online monitoring and quality control become an attractive prospective. In this regard, application of data analytics techniques offers a promising toolset for fast and efficient analysis. This work presents a pilot demonstration of an instrumented sheet metal cutting line that integrates online quality control and predictive maintenance concepts, namely detection of wear in tools as well as problems arising from the raw material and process. Automated sequential cutting was performed using a straight trimming die mounted on a hydraulic press to cut High-Mn TWIP steel strip. Three piezoelectric force sensors were located in the trimming tool, collecting cycle data. Tests performed included studying the effect of blunting on the M2 (1.3343) tool, as well as the influence of correct lubrication. The resulting data were analyzed through the extraction of several parameters from each cycle to correlate die wear-induced force response evolutions with the shear-induced deformation in High-Mn TWIP steel sheets. Extracted parameters were the maximum and minimum force of each cycle and the impulse (integrated force over time) was computed and segmented by plastic deformation and crack contributions. Our analysis show that advanced algorithms can be used to analyze sensor data on an automated installation, revealing OK/NOK conditions and anomalous events.

Smart Healthy Schools: An IoT-enabled concept for multi-room dynamic air quality control

Smart Healthy Schools (SHS) are a new paradigm in building engineering and infection risk control in school buildings where the disciplines of Indoor Air Quality (IAQ), IoT (Internet of Things) and Artificial Intelligence (AI) merge together. In the post-pandemic era, equipping schools with a network of smart IoT sensors has become critical to aspire for the optimal control of the IAQ and lowering the airborne infection risk of several pathogens, indirectly related to cumulated human emitted CO2 levels over time. Thermal energy waste in winter due to improved air renewal remains of major concern but can be well monitored within a SHS monitoring architecture thanks to the flexibility of the LoRaWAN protocol able to process also a large amount of energy and climatic data at room and building scale. In this work, we report the design of the AulaSicura platform, an IoT control system co-designed by the main author and Gizero Energie to implement the SHS paradigm via clearly visible (and audible) alarm signalling in existing and new school buildings. The cloud-based LoRa system is capable of continuous and simultaneous monitoring of a variety of sensors and IAQ parameters including indoor/oudoor temperatures, rel. humidities and human-emitted excess CO2. The multi-room monitoring concept of indoor-CO2 levels allows centralized control of natural ventilation levels in individual classrooms and can handle (quasi)-real-time data, relevant for data post-processing and future developments in (quasi)-real-rime assessment of IAQ and infection risk levels at single room scale. The sensor network is also extensible to up to one thousand of classrooms per LoRa-node allowing centralized control of entire school districts at an urban scale. Moreover, through Modbus-LoRa I/O converters, AulaSicura can also control the same amount of mechanical ventilation units per node either in pure or hybrid mechanical ventilation modes.

PERFECTION FROM INCEPTION: STANDARDS FOR BIOCHEMISTRY UNDERGRADUATE CERTIFICATE PRACTICAL

Objectives: The undergraduate biochemistry practical’s are the routine test performed in all the medical laboratories. Few of these have been certified practical by competency-based medical education. This will help the teachers access the depth of theoretical and practical knowledge as well as judge their communication skills. To detect the basic concept of quality control in the biochemistry laboratory. Methods: Quantitative analysis was conducted with a purposive sample, at the Noida International institute of medical sciences by the department of biochemistry. 150 students performed the practical on serum albumin in two batches after the demonstration by the faculty. The results were collected through Google forms. The mean, SD, coefficient of variation, and bias were calculated. Results: Both batches showed significant improvement in repeating the practical. Batch a performance was markedly improved after disclosing the optical density of the standard. Conclusion: Teaching basic quality standards used in the biochemistry laboratory and emphasizing the preanalytical errors made during the 1st year of practical’s, markedly improved the performance.

Environmental noise modeling, quality control, verification, and validation concepts

Over the past 30 + year's noise modeling has developed in all engineering fields. ISO 9001 has developed detail simulation validation criteria's for variouse engineering fields. Engineering software application for environmental noise modeling are just one of many fields that offer advanced simulation options. Unfortunately, the validation of environmental noise simulation is still under development. With the increase of environmental noise projects the model validation between test and simulation is scrutinized by the public or in court. The presentation discusses the definition of Model, Mathematical Model, Computational Model and Conceptual Models and the definition of Verification, Validation and Updating. What are the tools for quality assurance (QA) for the noise modeling software, software verification and project quality control (QC)? What is the state of noise modeling standards in North America? What are the uncertainties and variabilities that the environmental noise engineer can control? Are we sure that we are modeling a worst-case scenario? What can consultants do to improve the quality of noise simulations.

Mechanical vs calorimetric glass transition temperature in the oxidation of linoleic acid from condensed κ-carrageenan/glucose syrup systems

Lipid oxidation remains a concern leading to deterioration of the organoleptic quality in processed goods, but it should be minimized by considering changes in the structural properties of foods. The present work investigates the effect of glass transition temperature on the oxidation of linoleic acid at different concentrations of κ-carrageenan/glucose syrup. A combination of 0.5, 1, 2 and 3% (w/w) κ-carrageenan and 82.5, 82, 81, 80% (w/w) glucose syrup were mixed with 1.5% (w/w) linoleic acid and 0.5% (w/w) lecithin to prepare samples with a total solid content of 85% (w/w). Physicochemical properties of these mixtures were recorded using Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). This was followed by estimation of the mechanical (Tgm) and calorimetric (Tgc) glass transition temperatures using small deformation dynamic oscillation in-shear and modulated differential scanning calorimetry (MDSC). The linoleic acid oxidation in the condensed polysaccharide/co-solute system was evaluated by monitoring the accumulation of hydroperoxide (ROOH) with UV–vis spectroscopy over a wide temperature range (−25 to 0 °C). The oxidation phase was modelled following a sigmoidal kinetic model indicating initiation and propagation stages of lipid oxidation. ROOH production increased as a function of time and temperature. The structural relaxation of the polymeric matrix influenced the oxidation rate at the initiation stage. At the propagation phase, Tgm appears to control the rate of ROOH formation (kf) and decomposition (kd) in all preparations, as compared to Tgc, an outcome that makes the former an important concept of quality control.