Indoor Dust Concentrations Research Articles

Bisphenol S and Its Chlorinated Derivatives in Indoor Dust and Human Exposure.

Bisphenol S (BPS), an environmental endocrine disruptor, has been identified in global environmental matrices. Nevertheless, limited studies have investigated the presence of chlorinated analogues of BPS (Clx-BPSs) with potential estrogenic activities in environmental matrices. In this study, the occurrence of BPS and five types of Clx-BPSs was characterized in indoor dust (n = 178) from Hangzhou City. BPS was measurable in 94% of indoor dust samples, with an average level of 0.63 μg/g (<LD-2.4 μg/g). Among the detected Clx-BPSs homologues, Cl1-BPS (2-chloro-4-(4-hydroxyphenyl)sulfonylphenol; detection frequency 70%), Cl2-BPS-2 (2-chloro-4-(3-chloro-4-hydroxyphenyl)sulfonylphenol; 65%), and Cl2-BPS-1 (2,6-dichloro-4-(4-hydroxyphenyl)sulfonylphenol; 61%) were among the frequently detected Clx-BPSs. Cl1-BPS was the most abundant analyte, with an average of 0.048 μg/g (<LD-0.24 μg/g), followed by Cl2-BPS-1 (0.035 μg/g, <LD-0.14 μg/g), and Cl2-BPS-2 (0.031 μg/g, <LD-0.13 μg/g). Significant correlations in indoor dust concentrations were observed between BPS and Cl1-BPS (p < 0.01), as well as between BPS and Cl2-BPS-1 (p < 0.01). Moreover, an estimation was made for the total daily intake of Clx-BPSs via the ingestion of indoor dust by infants, children, and adults. This study presents the first evidence of the existence of Clx-BPSs in indoor dust, concurrently highlighting the necessity to address their potential human exposure risks.

A multi-environmental source approach to explore associations between metals exposure and olfactory identification among school-age children residing in northern Italy.

Metal exposures can adversely impact olfactory function. Few studies have examined this association in children. Further, metal exposure occurs as a mixture, yet previous studies of metal-associated olfactory dysfunction only examined individual metals. Preventing olfactory dysfunctions can improve quality of life and prevent neurodegenerative diseases with long-term health implications. We aimed to test the association between exposure to a mixture of 12 metals measured in environmental sources and olfactory function among children and adolescents residing in the industrialized province of Brescia, Italy. We enrolled 130 children between 6 and 13 years old (51.5% females) and used the "Sniffin' Sticks" test to measure olfactory performance in identifying smells. We used a portable X-ray fluorescence instrument to determine concentrations of metals (arsenic (As), calcium, cadmium (Cd), chromium, copper, iron, manganese, lead (Pb), antimony, titanium, vanadium and zinc) in outdoor and indoor deposited dust and soil samples collected from participants' households. We used an extension of weighted quantile sum (WQS) regression to test the association between exposure to metal mixtures in multiple environmental media and olfactory function adjusting for age, sex, socio-economic status, intelligence quotient and parents' smoking status. A higher multi-source mixture was significantly associated with a reduced Sniffin' Sticks identification score (β = -0.228; 95% CI -0.433, -0.020). Indoor dust concentrations of Pb, Cd and As provided the strongest contributions to this association (13.8%, 13.3% and 10.1%, respectively). The metal mixture in indoor dust contributed more (for 8 metals out of 12) to the association between metals and olfactory function compared to soil or outdoor dust. Among a mixture of 12 metals measured in three different environmental sources (soil, outdoor and indoor dust), we identified Pb, Cd and As measured in indoor dust as the main contributors to reduced olfactory function in children and adolescents residing in an industrialized area. Exposure to indoor pollution can be effectively reduced through individual and public health interventions allowing to prevent the deterioration of olfactory functions. Moreover, the identification of the factors that can deteriorate olfactory functions can be a helpful instrument to improve quality of life and prevent neurodegenerative diseases as long-term health implications.

A Review of the Distribution and Health Effect of Organophosphorus Flame Retardants in Indoor Environments.

As a replacement for polybrominated diphenyl ethers (PBDEs), organophosphorus flame retardants (OPFRs) have been widely used and detected in different indoor environments all over the world. This paper comprehensively describes the concentration levels and distribution information of 11 kinds of OPFRs from 33 indoor dust and 10 air environments, from which TBOEP, TCIPP, and TDCIPP were observed to have higher concentrations in indoor environments. The ΣOPFRs displayed higher concentrations in indoor dust than in indoor air due to the higher molecular weight and vapor pressure of ΣOPFRs in building decoration materials, specifically for TCIPP and TDCIPP compounds. Considering that it is inevitable that people will be exposed to these chemicals in the indoor environments in which they work and live, we estimated their potential health risks through three human exposure pathways and found that the ingestion exposure to TBOEP for toddlers in Japan may reach up to 1270.80 ng/kg/day, which comprises a significant pathway compared to dermal contact and indoor air inhalation. Specifically, the combined total exposure to OPFRs by air inhalation, dust ingestion, and dermal contact was generally below the RfD values for both adults and toddlers, with a few notable higher exposures of some typical OPFRs.

Determination of Perfluorooctanoic Acid (PFOA) in the Indoor Dust Matter of the Sicily (Italy) Area: Analysis and Exposure Evaluations.

Perfluorooctanoic acid (PFOA) in environmental matrices is increasingly being studied due to its environmental persistence, global occurrence, bioaccumulation, and associated human health risks. Some indoor environments can significantly impact the health of occupants due to pollutants in indoor air and household dust. To investigate the potential exposure of individuals to PFOA in specific confined environments, this study reports an analytical method and results concerning the determination of PFOA in household dust, used as a passive sampler. To the best of our knowledge, this paper represents one of the first studies concerning PFOA concentrations in indoor dust collected in the south of Italy, within the European region. A total of twenty-three dust samples were collected from two different areas of Sicily (Palermo and Milena), extracted, and analyzed by an UHPLC-QTOF-MS/MS system. Finally, PFOA exposure was estimated using a new index (Indoor PFOA Exposure Index, IPEX) that incorporates the PFOA levels in dust, exposure time, and the correlation between the PFOA in dust and blood. It was then compared across four different exposure groups, revealing that PFOA exposure for people working in chemistry laboratories was evaluated to be ten times higher than the exposure for homemakers.

Estimate of the maximum amount of dust adhering to skin and the upper limit of dust-skin adherence factor for young adults: An example from Changchun, China

Contaminants present in dust adhering to the skin can pose a significant risk to human health through dermal absorption and hand-to-mouth contact. The adhesion capacity of dust differs significantly from that of soil due to its physicochemical properties. Therefore, applying the raw soil exposure parameters to estimate the health risks associated with dermal exposure to dust may lead to erroneous conclusions. In this study, we quantified the maximum amount of dust that adhered to the skin (MADmax) and the upper limit of dust-skin adherence factor (DSAFmax) in 26 adults using element markers as a proxy for dust. The volunteers were exposed to dust and rinse water samples were collected from their hands, forearms, lower legs, and feet. We analyzed both the raw dust samples and the rinse water samples for 11 element markers, including Be, V, Cr, Mn, Co, Ni, Cu, Zn, Se, Ba, and Pb. The results showed that the MADmax of indoor dust and outdoor dust increased by 0.08–0.62 mg and 0.33–0.56 mg following a 1 cm2 increase in skin surface area, respectively. Based on best dust element markers, the body part-weighted dust-skin adherences (WDSAFmaxs) of indoor dust and outdoor dust were 0.35 and 0.64 mg/cm2, respectively. A smaller particle size and higher moisture content resulted in a larger DSAFmax. Only when indoor dust concentrations exceed 24.2 mg/m3 or outdoor dust concentrations exceed 44.3 mg/m3, can the WDSAFmax be applied directly in the health risk assessment of dermal exposure to dust. The method from this study can be re-applied in different regions, and the adherence data can help to improve future studies on the health effects of dermal exposure to dust.

Occurrence and risk of human exposure to organophosphate flame retardants in indoor air and dust in Hanoi, Vietnam

The presence and distribution of thirteen organophosphate flame retardants (OPFRs) were investigated in indoor air and dust samples collected in Hanoi, Vietnam. The total OPFRs (ƩOPFRs) concentrations in indoor air and dust samples were 42.3–358 ng m−3 (median 101 ng m−3) and 1290–17,500 ng g−1 (median 7580 ng g−1), respectively. The profile of OPFRs in both indoor air and dust indicated that tris(1-chloro-2-propyl) phosphate (TCIPP) was the most dominant compound with a median concentration of 75.3 ng m−3 and 3620 ng g−1, contributing 75.2% and 46.1% to ƩOPFRs concentrations in indoor air and dust, respectively, followed by tris(2-butoxyethyl) phosphate (TBOEP), with a median concentration of 16.3 ng m−3 and 2500 ng g−1, contributing 14.1% and 33.6% to ƩOPFRs concentrations in indoor air and dust, respectively. The levels of OPFRs in the indoor air samples and corresponding indoor dust samples showed a strong positive correlation. The total estimated daily intakes (EDItotal) of ƩOPFRs (via air inhalation, dust ingestion, and dermal absorption) for adults and toddlers under the median and high exposure scenarios were 36.7 and 160 ng kg−1 d−1, and 266 and 1270 ng kg−1 d−1, respectively. Among the investigated exposure pathways, dermal absorption was a primary exposure pathway to OPFRs for both toddlers and adults. The hazard quotients (HQ) ranged from 5.31 × 10−8 to 6.47 × 10−2 (<1), and the lifetime cancer risks (LCR) were from 2.05 × 10−11 to 7.37 × 10−8 (<10−6), indicating that human health risks from exposure to OPFRs in indoor environments are not significant.

Polyhalogenated carbazoles in indoor dust from Hangzhou, China

Carbazoles (CZ) and polyhalogenated carbazoles (PHCZs), showing dioxin-like toxicity, have gained increasing attention in recent years as novel persistent organic pollutants. However, the occurrence of these chemicals in indoor dust from China remains not well known. In this study, CZ and 11 chloro/bromo CZs were analyzed in indoor dust samples collected from residential houses in rural (n = 51) and urban (n = 55) regions of Hangzhou, China. CZ was detected in all indoor dust samples, with the concentrations of 0.81–18 ng/g (mean 5.4 ng/g). All 11 measured PHCZs were detected in indoor dust samples, showing the detection frequency of 7.3–96 %. This means that general populations had wide exposure to CZ and PHCZs through indoor dust ingestion. 3,6-dichlorocarbzole (36-CCZ) and 3,6-dibromocarbazole (36-BCZ) were the predominant PHCZs in indoor dust, having comparable mean concentrations of 1.2 ng/g, followed by 3-monobromocarbazole (3-BCZ; mean 0.66 ng/g, range < LOD–2.1 ng/g) and 1,3,6-tribromocarbazole (136-BCZ; 0.36 ng/g, < LOD–1.0 ng/g). Indoor dust concentrations of 3-BCZ, 36-BCZ, and 1,3,6,8-tetrabromocarbazole in urban regions were significantly (p ≤ 0.01–0.035) higher than that in rural regions. Daily intakes (DIs) of CZ and PHCZs through indoor dust ingestion were estimated for general Chinese population. Among PHCZs, 36-CCZ and 36-BCZ (mean 1.4–3.4 pg/kg bw/day) had the highest mean DIs, followed by 3-BCZ (0.77–1.9 pg/kg bw/day) and 136-BCZ (0.42–1.0 pg/kg/day). To our knowledge, this is the first study reporting the concentrations of CZ and PHCZs in indoor dust from China, which contributes to the better understanding of the sources of human exposure to CZ and PHCZs.

Cu, Pb, Zn,Cr and Cd concentrations in indoor dust in HadithaCity, Western Iraq, measured by washing with EDTANa2 - organic acid

In recent years, society's awareness of the presence of heavy metals in home dust has increased. Many cities have various levels of metal in their dust as a result of different regional pollution sources. Heavy metals are generated by both natural and man-made processes. The amount of heavy metals and minerals in the atmosphere is influenced by natural processes such as soil erosion, forest fires, volcanic eruptions, rock fracturing, dust, and forest fires. The sources of heavy metals in household dust include anything that people use or do in their houses, such as heaters, consumer products, building materials, and furniture. They also include activities like indoor smoking and incense burning, the color of the wall paint, as well as the entry of outside pollutants.In order to measure the levels of heavy metals ,the artificial chelating substance ethylenediaminetetraacetic acid disodium (EDTA) and low-molecular-weight organic acids (citric acid, oxalic acid, and tartaric acid) were chosen as the washing reagents. The washing solution utilized in the current study is made up of a mixture of (0.4 M) tartaric, oxyalic, and cetric organic acids and (0.2 M) EDTA. In accordance with the findings, the average amounts of these heavy metals in indoor dust were as follows: Zn (24.10± 15.93 mg/kg), Pb (19.52 ±14.74 mg/kg), Cr(8.73± 3.00 mg/kg), Cu (5.95 ±3.46 mg/kg), and Cd (3.25± 1.24 mg/kg).

A multi-environmental media approach to explore the association between metal exposure and the ability to identify smells among school-age children residing in Northern Italy

BACKGROUND AND AIM Inhalation of airborne particles can lead to olfactory dysfunction. We aimed to test the association between the exposure to a mixture of 12 metals measured in three environmental media and olfactory function among children and adolescents residing at different distances from ferromanganese alloy plants in the province of Brescia, Italy. METHODS We enrolled 130 children between 6 and 13 years old (51.5% females) residing in Valcamonica and Bagnolo Mella, respectively. The Burghart &amp;#x22;Sniffin` Sticks” test was used to investigate olfactory performance in identifying smells. Metal concentrations in soil, indoor, and outdoor deposited dust samples from the subjects’ households were analyzed with a portable X-ray fluorescence instrument. A Multi Environmental Media (MEM) Weighted Quantile Sum (WQS) regression for count data was applied to test for the association between the exposure to metals and child olfactory function. All models were adjusted by age, sex, socio-economic status, area of residence, intelligence quotient, BMI and passive smoking. RESULTS The metal mixture was negatively associated with the identification score (=-0.229; 95%CI -0.439, -0.018). Cadmium (17.0%), iron (13.0%), lead (11.5%) and arsenic (8.5%) provided the strongest contribution to the association. Indoor dust resulted as the environmental media with the strongest contribution to the association with olfactory function for most of the elements considered in the mixture. CONCLUSIONS We identified metal concentrations in indoor dust as a risk factor for olfactory dysfunction in children and adolescents residing close to ferroalloy plants. Indoor pollution can be improved through public health interventions; moreover, the identification of the factors that can deteriorate olfactory functions can also prevent neurodegenerative disease. KEYWORDS Environmental exposure; olfactory function; metal exposure; soil; outdoor dust; indoor dust.

Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China

Prevalences of allergies and asthma have increased through the past few decades around the world, especially in countries and regions that have adopted modern lifestyles. Epidemiological studies outside of China have found a relationship between phthalates concentrations in indoor dust and symptoms of respiratory, skin and nose allergies. The aim of our study is to investigate the association between children's asthma and allergic symptoms and concentrations of different phthalates in settled dust samples collected from children's homes in metropolitan Tianjin (Tianjin and Cangzhou), China. We selected 126 cases with current allergic symptoms and 254 controls without allergic symptoms from the cohort of 7865 children. We collected dust samples from children's bedroom and analyzed them for their content of diethyl phthalate (DEP), diisobutyl phthalate (DiBP), di-n-butyl phthalate (DnBP), butylbenzyl phthalate (BBzP), di-2-ethylhexyl phthalate (DEHP) and diisononyl phthalate (DiNP). We found a higher concentration of DEP in rhinitis children's homes (0.33 vs. 0.27μg/g dust) and a higher concentration of DiBP in asthma children's homes (29.04 vs. 15.66μg/g dust). The concentration of DiBP was significantly associated with diagnosed asthma (adjusted odds ratio (AOR): 1.30; 95% confidence interval (CI): 1.07, 1.57). A dose-response relationship was found between concentrations of DiBP in dust and asthma. This study shows that some phthalates are associated with allergic and asthma symptoms in children.

Polycyclic aromatic hydrocarbons and polybrominated diphenyl ethers inside university campus: Indoor dust-bound pollution characteristics and health risks to university student

This study examined indoor dust-bound pollution characteristics of polycyclic aromatic hydrocarbons (PAHs) and polybrominated diphenyl ethers (PBDEs), and the health risk to these pollutants of university students inside a university campus in Xinxiang, central China. Indoor dust samples (n = 52) were obtained from the student dormitories, classrooms, laboratories, and offices. The average concentration of ∑16PAHs was 2060 ± 1290 ng/g dry weight (dw). Phe and 4-ring PAHs showed the highest concentration and contribution. The PAH concentrations in indoor dust from various types of room showed significant difference (p ˂ 0.05), and the highest concentration was found in laboratory. The ∑16PBDEs concentration was 364 ± 379 ng/g, and BDE209 was the prime PBDE congener and showed the highest contribution. PBDE concentrations also showed significant difference (p ˂ 0.05) among different types of indoor dust, and the girls’ dormitory showed the highest PBDEs concentration. Petroleum, petroleum combustion, and biomass/coal combustion were the main sources of PAHs. Deca-BDE (BDE209) was the main source of PBDEs, and low-brominated PBDEs were mainly derived from the degradation of high-brominated PBDEs. Correlation analysis showed that PAH and PBDE had similar pollution sources. The estimated daily intake (EDIs, mg/(kg·day)) of the ∑16PAHs was 694 ± 434. The BaP equivalent (BaPE) value for PAHs in indoor dust was 113 ng/g, and laboratory showed the highest BaPE values. The EDIs of the ∑16PBDEs were 123 ± 128 mg/(kg·day), and the non-cancer hazard index (HI) indicated PBDEs may pose adverse health effects to university students.

Concentrations and human exposure to hexabromocyclododecane and tetrabromobisphenol A from the indoor environment in Bangkok metropolitan area, Thailand

Aim: This study investigated hexabromocyclododecane (HBCDD) and tetrabromobisphenol A (TBBPA) concentrations in indoor dust from houses, offices, and cars and estimated toddler and adult exposure to HBCDD and TBBPA through dust ingestion. Methods: The concentrations of HBCDD and TBBPA were measured in 47 indoor dust samples collected from the Bangkok metropolitan area, Thailand. All samples were analyzed for HBCDD and TBBPA using LC-MS/MS. The estimated daily intake (EDI) through dust ingestion was calculated from the median and 95th percentile concentrations of HBCDD and TBBPA. Results: HBCDD was detected in 47% of samples, and TBBPA was detected in all samples. The median concentrations of HBCDD were 6.7 ng g-1, &lt;0.7 ng g-1, and &lt;0.7 ng g-1 in cars, houses, and offices, respectively. The isomer composition of ∑HBCDD in dust was: α-HBCDD (40%-54%), γ-HBCDD (19%-40%), and β-HBCDD (17%-28%). In contrast, TBBPA was observed at higher concentrations, with median values of 674, 67, and 22 ng g-1 in offices, houses, and cars, respectively. Under a median exposure scenario, toddlers were exposed to 0.05 ng kg-1 bw day-1 for HBCDD and 0.25 ng kg-1 bw day-1 for TBBPA, with adults exposed to 0.01 and 0.06 ng kg-1 bw day-1 for HBCDD and TBBPA respectively. Conclusion: Concentrations of HBCDD in dust from Thai cars, homes, and offices are lower than those of TBBPA following the listing of HBCDD in the Stockholm Convention on Persistent Organic Pollutants and limited use of HBCDD in Thailand in applications such as building insulation foam. Concentrations of TBBPA in office dust significantly exceeded (P &lt; 0.05) those in house and car dust owing to the greater number of electronic appliances and poor natural ventilation in offices. EDIs for Thai toddlers exceeded those of adults under both median and high-end exposure scenarios. However, EDIs of HBCDD and TBBPA for the general Thai population were below the corresponding oral reference dose guidelines.

In vitro Phase I metabolism of newly identified plasticizers using human liver microsomes combined with high resolution mass spectrometry and based on non-targeted and suspect screening workflows

Three plasticizers, namely bis (3,5,5-trimethylhexyl) phosphate (TMHPh), di(propylene glycol) dibenzoate (DiPGDB), and tri-n-butyl trimellitate (TBTM), were recently identified and reported in high concentrations in indoor dust from Belgian homes. In this study, their behavior within the human body was investigated by generating Phase I biotransformation products for the first time. Human liver microsomes (HLMs) were used following an in vitro assay and liquid chromatography time of flight mass spectrometry (LC-QTOF-MS) was employed for the analysis. Biotransformation products were identified for TMHPh as products of hydroxylation reactions that took place in one or two positions in the structure of the substrate. For DiPGDB, biotransformation products were formed after hydrolysis of carboxylic esters and oxidative-O-dealkylation. For TBTM, biotransformation products were formed through hydrolysis of the different carboxylic esters of the molecule, in agreement with studies on structurally similar compounds. The generated results can contribute to biomonitoring studies creating new knowledge on human exposure to emerging compounds and on the metabolism of xenobiotics.

Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption.

Human exposure to OPEs is pervasive and should be of great concern due to associations with adverse health effects, especially in susceptible populations. In this study, body burdens and exposure pathways of OPEs were investigated for 76 healthy elderly people in Jinan, China based on the measured OPE and metabolite concentrations in human bio-samples (whole blood and urine) and paired environmental matrices (air and dust), as well as food frequency questionnaire. Eight of 16 OPEs and 5 of 11 metabolites were detected in>50% of whole blood and urine samples, respectively. Tri(1-chloro-2-propyl) phosphate (TCIPP), tris(2-chloroethyl) phosphate (TCEP), tri-phenyl phosphate (TPHP), and 2-ethylhexyl di-phenyl phosphate (EHDPP) were frequently detected and abundant in whole blood, while their corresponding metabolites were detected at low frequencies or levels in urine. The reduced metabolic and/or excretory capacity of elderly people may be an important reason, implying a higher health risk to them. Fourteen OPEs had over 50% detection frequencies in indoor air and dust, while 6 di-esters in indoor dust. Tris(2-ethylhexyl) phosphate (TEHP) in indoor dust and tri-n-butyl phosphate (TnBP) in indoor air were positively correlated with paired levels in blood but not with their metabolites (BEHP and DnBP) in urine. Combined with the direct intakes of BEHP and DBP from dust, blood is indicated as more suitable biomarker for TEHP and TnBP exposure. High consumption frequencies of several foods were associated with higher blood concentrations of three OPEs and urinary levels of four di-OPEs, indicating the importance of dietary exposure pathway. Estimated daily total intakes of OPEs via inhalation, dust ingestion, and dermal absorption ranged from 2.78 to 42.0ng/kg bw/day, which were far less than the reference dosage values. Further studies were warranted to explore the potential health effects of OPE exposure in the elderly populations.

Sources and composition of metals in indoor house dust in a mid-size Canadian city

House dust is an important medium for exposure to persistent pollutants, such as metals. Detailed characterization of metal composition is needed to identify sources and potential health impacts of exposure. In this study we show that specific metals in dust dominate in different locations within residential homes in a mid-size Canadian city (Fort McMurray, Alberta), up to two years after a major wildfire event in 2016. Dust samples were collected in high-traffic (e.g. bedroom, N = 186), low-traffic (e.g. basement, N = 158), and entranceway areas (N = 171) of residential homes (N = 125), and analyzed for 25 trace metal elements using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The profile of metal concentrations in the entranceway resembled that of outdoor soils, especially for crustal elements. On the other hand, Cu, Zn, and Pb concentrations in dust sampled in indoor living areas were on average three to six times higher than in other indoor locations indicating indoor sources for these elements. In general, Pb concentrations were similar or lower than in an average Canadian residence, but a substantial fraction showed anomalously high concentrations in the low-traffic areas, particularly on concrete surfaces in basements. Notably, the 2016 wildfires showed limited influence on metal concentrations in indoor dust, despite the widespread concerns in the community about long term exposure. Enrichment factor ratio calculations and principal component analysis showed two classes of sources of metals in dust that represent geogenic-outdoor sources and anthropogenic-indoor sources. Overall, we demonstrate that outdoor and indoor sources of dust impact its composition, and these influences are reflected in the different areas of a home.

Human health risks from brominated flame retardants and polycyclic aromatic hydrocarbons in indoor dust

Exposure to dust particles containing toxic compounds is linked to serious health outcomes, including cancer. The purpose of this study was to determine if indoor dust from houses and cars contained harmful levels of brominated flame retardants (polybrominated diphenyl ethers, PBDEs) and polycyclic aromatic hydrocarbons (PAHs), and to assess their potential toxicity to adults and children. In Kuwait, the median concentration of total PBDEs (Ʃ14- PBDEs) was 408.55 μg PBDEs/kg dust in houses and twice as high in cars (838.52 μg PBDEs/kg dust), while total PAHs (Ʃ16-PAHs) were similar in houses (992.81 μg PAHs/kg) and cars (900.42 μg PAHs/kg). The PBDEs and PAHs concentrations in indoor dust were related to house age and square footage, car model year, and natural ventilation. Furthermore, a higher PBDEs concentration was associated with electronic devices that operate continuously, furniture containing foam treated with PBDEs, and cars that are parked outdoors, since PBDEs tend to be volatilized under these conditions. The PAHs concentration in indoor dust increased with smoking and proximity to major roads and industrial facilities, which are major PAHs sources. The hazard quotient and total cancer risk for PBDEs in indoor dust were within safe limits, but indoor dust with higher PAHs concentrations had hazard quotients from 5.51 to 11.23 and total cancer risk of 10−3 for adults and children. We conclude that exposure to PAHs-contaminated indoor dust from houses and cars where smoking occurs can increase the cancer risk of adults and children.

Occurrence of bisphenols and phthalates in indoor dust collected from Korean homes

Indoor environments are a major source of exposure to contaminants for children owing to long indoor residence time. In particular, endocrine-disrupting chemicals, such as bisphenols and phthalates, which are widely used in household products, are one of the major contaminants in indoor air or dust. Bisphenols and phthalates are ubiquitous in consumer products including toys, packaging, and cosmetics. We investigated the occurrence of 8 bisphenol and 16 phthalate analogues in the indoor dust collected from 49 houses in Korea. The results showed that the concentrations of bisphenol A (BPA) and di(2-ethylhexyl)phthalate (DEHP) were the highest in indoor dust. This was due to the large production volume and relatively low vapor pressure of these compounds. Finally, we attempted to find a correlation between the BPA and DEHP concentrations in indoor dust. A boomerang-shaped pattern was observed between the DEHP and BPA concentrations. It was concluded that the high concentration of DEHP in one part of the boomerang curve might be due to the increase in the usage of plastic products with age.

Differences of bisphenol analogue concentrations in indoor dust between rural and urban areas

Bisphenol analogues (BPs) are widely applied in varying consumer products. Many studies have reported their presence in indoor dust samples from China. However, the differences in occurrence and concentration profiles of BPs in indoor dust between rural and urban areas are still not well characterized. In this study, eight BPs were measured in 60 indoor dust samples collected from rural and urban districts of Hangzhou, China. Bisphenol A (BPA; mean 1.8 μg/g, range 0.20–7.2 μg/g) was the predominant BP in indoor dust samples, accounting for mean 57% of the total BP (∑BP) concentration, followed by bisphenol S (BPS; 0.58 μg/g, <LOD–2.4 μg/g) and bisphenol AF (0.43 μg/g, <LOD–2.6 μg/g). Indoor dust samples from the urban areas (n = 27) contained significantly (p < 0.05) higher levels of ∑BPs, BPA, and BPS than that from the rural areas (n = 33). Comparatively, bisphenol F and bisphenol AP were more frequently detected in urban indoor dust samples. Daily intakes (DIs) of BPs through the indoor dust inhalation were estimated for infants, children, and adults. Infants had much higher (p < 0.01) DIs of BPs than children and adults, mainly owing to their lower body weights and higher indoor dust ingestion rates. To our knowledge, this is one of the first studies examining the regional differences of BP concentrations in indoor dust from China, which could contribute to the more accurate evaluation of human BP exposure through indoor dust intake.

Prevalence of phthalate alternatives and monoesters alongside traditional phthalates in indoor dust from a typical e-waste recycling area: Source elucidation and co-exposure risk

This study first discovered the prevalence of phthalate (PAE) alternatives and PAE monoesters alongside traditional PAEs with elevated concentrations in indoor dust from typical e-waste recycling industrial park and adjacent communities. Among nine PAEs, high-molecular-weight (HMW) PAEs dominated over low-molecular-weight (LMW) PAEs in e-waste dust, with total concentrations (∑9PAEs) ranging from 170 to 5300 μg g−1. The diisononyl phthalate (DiNP) was identified as the most abundant PAE in e-waste dust, with over 10 times higher median concentration than that measured in home dust. Total concentrations of three PAE alternatives ranged from 20 to 1600 μg g−1 in e-waste dust, which were 3–10 times higher than the measured levels in home dust. A total of 13 monoesters were all identified in all samples with total concentrations of 4.7–59 μg g−1, and biodegradation of diesters was recognized as the major source of monoesters present in indoor dust. Significant correlations between the concentrations of PAE alternatives and the HMW PAEs were observed (p < 0.05), indicating that they are being simultaneously used in electronic and electrical products. The occupationally high co-exposure of e-waste dismantling workers to multiple PAEs and PAE alternatives as well as their monoesters should be of concern.

Human Exposure to Chlorinated Paraffins via Inhalation and Dust Ingestion in a Norwegian Cohort.

Very-short- (vSCCPs, C6–9), short- (SCCPs, C10–13), medium- (MCCPs, C14–17), and long-chain chlorinated paraffins (LCCPs, C>17) were analyzed in indoor air and dust collected from the living rooms and personal 24 h air of 61 adults from a Norwegian cohort. Relatively volatile CPs, i.e., vSCCPs and SCCPs, showed a greater tendency to partition from settled indoor dust to paired stationary indoor air from the same living rooms than MCCPs and LCCPs, with median logarithmic dust–air partition ratios of 1.3, 2.9, 4.1, and 5.4, respectively. Using the stationary indoor air and settled indoor dust concentrations, the combined median daily exposures to vSCCPs, SCCPs, MCCPs, and LCCPs were estimated to be 0.074, 2.7, 0.93, and 0.095 ng/kg bw/d, respectively. Inhalation was the predominant exposure pathway for vSCCPs (median 99%) and SCCPs (59%), while dust ingestion was the predominant exposure pathway for MCCPs (75%) and LCCPs (95%). The estimated inhalation exposure to total CPs was ∼ 5 times higher when the personal 24 h air results were used rather than the corresponding stationary indoor air results in 13 paired samples, indicating that exposure situations other than living rooms contributed significantly to the overall personal exposure. The 95th percentile exposure for CPs did not exceed the reference dose.