Concentration Of Peel Extract Research Articles

Effect of orange fruit peel extract concentration on the synthesis of zinc oxide nanoparticles.

In this investigation, the impact of reducing agent concentration on the synthesis of zinc oxide nanoparticles (ZnO NPs) was examined. During the synthesis, an assessment of ionic conductivity was carried out, revealing a significant increase in conductivity prior to the introduction of the reducing agent, followed by a sharp decrease upon its addition. Characterization of the ZnO NPs involved ultraviolet-visible spectroscopy, scanning electron microscopy, Fourier-transform infrared spectroscopy, and, X-ray diffraction analysis. The outcomes suggest that the characteristics of the ZnO NPs are influenced by the concentration of the reducing agent during the synthesis process. Notably, the ZnO NPs synthesized with a higher concentration of reducing agent exhibited a narrower optical band gap and increased surface energy. Furthermore, employing a concentration of 0.5 v/v resulted in the rapid production of NPs with relatively uniform sizes. Conversely, concentrations below 0.5 v/v lead to slow formation, while concentrations exceeding 0.5 v/v yielded non-uniform NPs.

HASIL PEMERIKSAAN TELUR SOIL TRANSMITTED HELMINTH MENGGUNAKAN CAMPURAN PEWARNA ALAMI DARI DAUN MIANA DAN KULIT BUAH NAGA

The simplest method for checking worm eggs is by a native technique using a 2% eosin reagent. Eosin itself has properties that are not easily decomposed, causing hazardous and easily flammable waste. Hence, an alternative staining method is needed, environmentally friendly, using natural materials, such as natural dye substances. This research aims to understand the depiction of results in examining Soil Transmitted Helminth (STH) eggs using mint leaves and dragon fruit skin as alternative reagents. The research method involves examining feces using a direct method (wet preparation) to detect worm eggs in feces directly using a 2% Eosin solution. The comparison results between dragon fruit peel extract concentration using aquadest, tested with SPSS analysis version 20 using the Kruskal-Wallis method with a significance value of 0.09 ≥ 0.05, indicating significantly different research outcomes. Thus, it can be concluded that there is no difference in staining quality compared to the control. The conclusion drawn from this study is that there's no difference in staining worm egg suspensions using mint leaf extract. This is evident as when observing the worm egg suspension using mint leaf extract, the worm eggs were not clearer, unlike with dragon fruit skin and miana.

Green synthesis of gold nanoparticles via Artocarpus odoratissimus peel extract for potential applications of optical filter and catalytic degradation

Gold nanoparticles (Au NPs) were synthesized via a green synthesis method, utilizing the peel extract of Artocarpus odoratissimus as both the reducing and capping agent. This study investigates the impact of peel extract concentration (ranging from 0.002 to 0.012 g/mL) and reaction temperature (including room temperature, 45 °C, and 75 °C) on the properties of the synthesized Au NPs. Various characterization techniques, such as UV–Visible spectrophotometry, transmission electron microscopy (TEM), Fourier Transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD), and zeta potential analysis, were employed to analyze the synthesized samples. UV–Visible spectroscopy revealed absorption peaks of the Au NPs around 533–537 nm, varying with synthesis parameters, while TEM analysis indicated particle sizes ranging from 12 to 25 nm. XRD analysis confirmed the formation of Au NPs, with diffraction peaks aligning well with the standard. FTIR analysis suggested interactions between phytochemicals and Au NPs, contributing to their reduction and size control. The synthesized Au NPs exhibited remarkable optical filtering capability, with up to 87 % transmittance in the 751–1126 nm spectral range and significant absorbance in the lower wavelength region (300–751 nm). Additionally, catalytic studies revealed that Au NPs accelerated the degradation of rhodamine B dye, 0.0795 min−1, compared to 0.0445 min−1 without Au NPs. These findings underscore the potential of Au NPs for use in hybrid photovoltaic-thermal systems as filters, where transmitted light can be harvested for photovoltaic energy generation while absorbed light can be utilized for the thermal aspect. Moreover, Au NPs offer promise for improving wastewater quality by enhancing pollutant degradation.

Plackett–Burman screening of physico-chemical variables affecting Citrus peel-mediated synthesis of silver nanoparticles and their antimicrobial activity

With the growing resistance of pathogenic microbes to traditional drugs, biogenic silver nanoparticles (SNPs) have recently drawn attention as potent antimicrobial agents. In the present study, SNPs synthesized with the aid of orange (Citrus sinensis) peel were engineered by screening variables affecting their properties via Plackett–Burman design. Among the variables screened (temperature, pH, shaking speed, incubation time, peel extract concentration, AgNO3 concentration and extract/AgNO3 volume ratio), pH was the only variable with significant effect on SNPs synthesis. Therefore, SNPs properties could be enhanced to possess highly regular shape with zeta size of 11.44 nm and zeta potential of − 23.7 mV. SNPs purified, capped and stabilized by cloud point extraction technique were then checked for their antimicrobial activity against Bacillus cereus, Listeria innocua, Listeria monocytogenes, Staphylococcus aureus, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium and Candida albicans. The maximum antimicrobial activity of SNPs was recorded against E. coli, L. monocytogenes and C. albicans with clear zone diameter of 33.2, 31.8 and 31.7 mm, respectively. Based on minimum inhibition concentration and minimum bactericidal concentration of SNPs (300 mg/l) as well as their effect on respiratory chain dehydrogenases, cellular sugar leakage, protein leakage and lipid peroxidation of microbial cells, E. coli was the most affected. Scanning electron microscopy, protein banding and DNA fragmentation proved obvious ultrastructural and molecular alterations of E. coli treated with SNPs. Thus, biogenic SNPs with enhanced properties can be synthesized with the aid of Citrus peel; and such engineered nanoparticles can be used as potent antimicrobial drug against E. coli.

Effect and Mode of Different Concentrations of Citrus Peel Extract Treatment on Browning of Fresh-Cut Sweetpotato.

Browning is one of the main phenomena limiting the production of fresh-cut sweetpotatoes. This study investigated the anti-browning effect of citrus peel extracts and the key components and modes of action associated with browning in fresh-cut sweetpotatoes. Five different concentrations of citrus peel extract (1, 1.5, 2, 2.5 and 3 g/L) were selected to ensure storage quality; and the physical and chemical properties of fresh-cut sweetpotato slices were analysed. A concentration of 2 g/L of citrus peel extract significantly inhibited the browning of fresh-cut sweetpotatoes. The results showed that the browning index and textural characteristics of fresh-cut sweetpotatoes improved significantly after treatment with citrus peel extract; all the citrus peel extract solutions inhibited browning to some extent compared to the control. In addition; LC-IMS-QTOFMS analysis revealed a total of 1366 components in citrus peel extract; the evaluation of citrus peel extract monomeric components that prevent browning in fresh-cut sweetpotato indicated that the components with better anti-browning effects were citrulloside, hesperidin, sage secondary glycosides, isorhamnetin and quercetin. The molecular docking results suggest that citrullosides play a key role in the browning of fresh-cut sweetpotatoes. In this study, the optimum amount of citrus peel extract concentration was found to be 2 g/L.

Effect of Variation of Concentration of Ketapang (Terminalia Catappa) Fruit Extract on The Corrosion Rate of ASTM A36 Iron

The aim of this study was to investigate the influence of varying concentrations of Terminalia catappa fruit peel extract on the corrosion rate during immersion periods of 2 days, 4 days, and 6 days for ASTM A36 steel. The ASTM A36 steel specimens were immersed in a corrosive medium containing 2% NaCl, with inhibitor compositions of 0%V, 1%V, 2%V, and 3%V being tested. Measurement results revealed that as the concentration of Terminalia catappa fruit peel extract increased, the corrosion rate proportionally decreased. The lowest corrosion rate was observed in samples with a 3%V inhibitor composition, subjected to a 4-day immersion, measuring at 0.02321 mmpy. Moreover, with the augmentation of fruit peel extract concentration, inhibition efficiency exhibited an augmented trend (83.02% for the 3%V composition, and the lowest at 41.84% for the 1%V composition).

The Effectiveness of Duku Kumpeh Skin Extract Aromatherapy Candles to Repel Dengue Haemorrhagic Fever Mosquitoes

Dengue Hemorrhagic Fever is a health problem that has become a significant topic internationally. In Indonesia, DHF is still a disease with a high incidence rate. Quoted from the Sehat Negeriku website, in 2020, there were 95,893 cases of dengue fever, with the number of deaths from dengue reaching 661 people. To ensure a healthy life and encourage prosperity for all people of all ages to achieve goal number 3 of the Sustainable Development Goals, it is necessary to take preventive measures against this disease. The specific purpose is to know the number of dead mosquitoes with a concentration of 1% duku peel extract in wax. Knowing the number of mosquitoes killed with a duku peel extract concentration of 2% in resin, It is known that the number of dead mosquitoes with a concentration of 3% duku peel extract in wax.
 This research is an experimental study with a completely randomized design (Completely Randomize Design) Duku bark extract wax was made by varying the concentration of duku bark extract to 1%, 2%, and 3%. Based on the data in the table, the highest Aedes aegypti mosquito mortality rate was obtained at a concentration of 3%, with the highest number of mosquito deaths, namely 49 mosquitoes. Whereas at a concentration of 2%, the number of mosquitoes that died was 25, and at a concentration of 3%, the number of mosquitoes that died was 25. Duku bark extract wax is categorized as good and can be used as a vegetable insecticide.

The Effectiveness of Using Jengkol Peel Extract (Pithecellobium lobatum Benth.) in Inhibits Bacterial Growth Staphylococcus aureus In Vitro

Staphylococcus aureus is aerobic bacteria that are gram-positive and are one of the normal human flora on the skin and mucous membranes. Most infections in the oral cavity are caused by Staphylococcus aureus, which is a normal flora in the oral cavity that can turn into a pathogen if trauma or abrasion occurs on the mucosal surface. Jengkol peel is thought to contain tannin compounds, which have the potential as an anti-inflammatory, anti-diarrheal, antioxidant, treatment of infections of the skin and mouth, and treatment of burns. This study aimed to explore the potential of jengkol peel extract (Pithecellobium lobatum Benth.) as an antibacterial Staphylococcus aureus regularly in vitro. This study is an experimental research in vitro, where as many as 7 treatment groups were used in this study. Positive and negative controls and extract concentrations of 5%-80% were used as the treatment group. Analysis of the average diameter of the inhibition of bacterial growth was carried out using SPSS version 25 software. The potential inhibition of jengkol peel extract was in line with the increase in the concentration of jengkol peel extract. The higher the concentration of jengkol peel extract, the greater the inhibition of bacterial growth. Extract concentration of 20% has a comparable inhibition of bacterial growth control positive. Jengkol peel extract effectively inhibits the growth of Staphylococcus aureus bacteria. Jengkol peel extract concentration of 20% has effectiveness in inhibiting bacterial growth equivalent to 0.2% chlorhexidine in vitro.

A novel method for the green utilization of waste fried oil

Waste fried oil was studied to prepare three different types of detergent such as soap, liquid soap and soap powder via saponification process. The preparation conditions of soap base were optimized by orthogonal experiment. The specific preparation processes included waste fried oil treatment, orange peel extract preparation, saponification, demoulding and drying. Results showed that the optimal conditions for saponification were as follows: ratio of pure waste fried oil to coconut oil = 6:4, alkali liquor (NaOH) mass fraction 30%, saponification temperature 70 °C, orange peel extract concentration 15%. The mature soap was then used to make liquid soap and soap powder by surfactant (sodium dodecylbenzene sulfonate, coconut diethanol amide) addition, followed by grinding. The prepared detergent conforms to the production standard of strong decontamination ability, possesses stable performance, is gentle to skin and non-toxic.

Pemanfaatan Ekstrak Kulit Buah Naga Merah sebagai Pewarna Alami Minuman Probiotik Sari Buah Sirsak

Background Soursop is one type of fruit with high productivity, but its utilization is relatively less than other fruits. This imbalance causes many soursop fruits to be damaged, so it needs to be processed into functional food in the form of probiotic drinks. Making soursop fruit juice probiotic drink utilizes Lactobacillus plantarum 1 RN2-53 as a starter, but the resulting product has an unattractive color. The addition of red dragon fruit peel extract is expected to provide an attractive color and increase the nutritional value and benefits of probiotic drinks.
 Research purposes The study aimed to obtain the best red dragon fruit peel-extract concentration as a natural dye for soursop probiotic drinks.
 Method: The sample used was a soursop probiotic drink with the addition of red dragon fruit peel extract using five different concentration levels, namely 5%, 10%, 15%, 20%, and 25%. The Hunter color system method used a colorimeter to conduct the color test.
 Results and Discussion: Red dragon fruit peel extract with 5%, 10%, 15%, 20%, and 25% significantly affected the microbiological, Physico-chemical, and sensory characteristics of the soursop probiotic drink. Anthocyanin dyes in red dragon fruit peel increase a* value in the color test, the percentage of total titrated acid and total LAB, and decrease the pH value, b* value, and L* value in the color test.
 Conclusion: The N5 treatment with the addition of 25% (b/b) concentration of red dragon fruit peel extract resulted in a pH value of 3.88, total acid titrated 0.71%, total LAB 9.22 log CFU/ml, color test value L* 24 ,19, color test a* 4.09 and color test b* -2.65.

The Effect of Shallot Peel (Allium ascalonicum L.) as a Natural Growth Regulatory Substance on Root Growth of Cassava Stem Cuttings (Manihot utilissima)

The effect of shallot peel (Allium ascalonicum L.) as a natural growth regulatory substance on root growth of cassava stem cuttings (Manihot utilissima). This study aims to determine the effect of shallot peel extract on root growth of cassava stem cuttings and determine the most effective treatment for root growth of cassava stem cuttings. This study used a completely randomized design consisting of 1 factor, namely the treatment of shallot peel extract concentration which had 10 levels (concentration 0%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80 %, 90% and 100% of shallot peel extract) and 3 replicates. The variables observed in this study were the number of roots and the longest root length from the roots of cassava stem cuttings. The data obtained were analyzed using the ANOVA test and the HSD (Honestly Significance Different) follow-up test with an error rate of 5%. The results showed that the treatment of shallot peel extract had a significant effect on the root growth of cassava stem cuttings. The most effective concenstration of shallot peel for root number growth was 20%, while for root length growth the most effective concentration was 30%.

Implementation of Ambon Banana Peel (Musa Paradisiaca) as Foaming Agent of Banana Fruitghurt using Foam Mat Drying Method

Fruitghurt is a product of lactic acid fermentation, namely L. bulgaricus and S. Thermopillus in an acidic state enriched by nutrients from fruit such as Ambon banana but has a short shelf life. Bananas have a role as an additional nutrient in the form of glucose which then becomes a nutrient for lactic acid bacteria. Foam mat drying itself is a drying method that is better than other types of drying because it does not require large production costs and protects the structure of the material through the formation of foam. Application of foam mat drying on fruitghurt using Ambon banana peel extract as a foaming agent is expected to increase the shelf life of fruitghurt as well as an alternative foaming agent derived from vegetable protein Ambon banana peel contains a protein content of about 0.64% when bananas experience a good level of maturity. In the manufacture of fruitghurt powder, the research method used is Response Surface Methodology (RSM) with variables changing the concentration of banana peel extract as a foaming agent, the concentration of maltodextrin as a binder and mixing time. The resulting fruitghurt powder will be analyzed for water content, total acid analysis and pH analysis. The research data were processed using minitab 19 software. The best fruitghurt powder results were found in the 9th variable, namely the minimase variable, where the optimum conditions were banana peel extract concentration of 2.38 ml, maltodextrin concentration of 30 grams and stirring time of 20 minutes. Fruitghurt variable 9 has a pH of 5 after drying which is in accordance with SNI 01-2981-2009, water content is 0.64% and total acid is 1.08%

Growth of Candida albicans colony on heat cured acrylic plat in inclusion of lime fruit extract (Citrus aurantifolia) 40% as desinfectant

Heat cured acrylic (HCA) resin has a rough, hard and porous surface. This causes food scraps to stick frequently and makes it easier for Candida albicans to grow. Lime peel extract (citrus aurantifolia) is a natural ingredient that is antifungal. The pur-pose of this study was to determine the growth of C.albicanscolonies on heat cured acrylic dentures in 40% immersion of lime peel extract. The HCA resin plate samples were 40 samples, namely the 40% lime peel extractconcentration group, the negative control group (akuades) and the positive control group which were soaked for 2 hours and 6 hours. The design of this study was a post-test only control group with data analysis using the one-way Anova test. The results showed that each group was normally distributed and the variance data was heterogeneous (p>0.05). It is concluded that 40% lime peel extract can inhibit the growth of C.albicans colonies on HCA resin plates.

ANTI-BACTERIAL ACTIVITY TESTING OF ETHANOL EXTRACT 96% PAINAGE SKIN (ANANAS COMOSUS (L.) MERR) AGAINST ESCHERICHIA COLI BACTERIA)

Pineapple peel (Ananas comosus (L.) Merr) is waste form the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Escherichia coli. Escherichia coli is a bacterium that generally lives in the large intestine of humans can become a pathogen when it reaches tissues outside the digestive tract which can cause diarrheal disease. The pineapple peel extract is made by using the ectraction method in the form of meceration. The method used in the inhibitory test using the two replication sampels in each treatment groups. The samples consisted of 6 treatment groups is pineapple peel extract concentration 25mg/ml, 50mg/ml, 75mg/ml, and 100mg/ml, as well as positive and negative control. The results obtained from pineapple screening contain alkaloi, flavonoid, tanin, and saponin compounds. The data analysis showsthat pineanepple peel extract concentrations of 25mg/ml, 50mg/ml, 75mg/ml, and 100mg/ml had inhibitory sones with the medium-strong category while ciproloxacin as the control has a strong inhibition zone. The conclusion that while the extract concentration increases, the diameter of the inhibition zone increases.

Comparative study on cupric oxide nanoparticles synthesis in saline buffer versus basic water by Spondias mombin peel extract for biocatalysis

The authors herein compared the morphology, homogeneity and biocatalytic (peroxidase) activity of the synthesized cupric oxide nanoparticles (CuO NPs) from Spondias mombin peel extract for the first time in saline buffer and basic H2O system respectively. The saline buffer-assisted synthesis of CuO NPs produced homogenous and monoclinic shaped nanoparticles having excellent peroxidase activity compared to basic H2O. The saline buffer-assisted synthesis of CuO NPs was optimized in terms of peel extract concentration, time, and light. The study about elemental compositions, crystallinity, size and shape of CuO NPs (average size ⁓ 45 nm and monoclinic shape in PBS system) were confirmed through EDS, XRD, and SEM techniques. And the completion of CuO NPs synthesis within 5 minutes much shorter than the basic H2O system was confirmed through UV-visible studies. Finally, the saline buffer-assisted CuO NPs showed 10 times higher peroxidase activity against TMB-H2O2 system than basic H2O-system.

EXTRACT OF MANGOSTEEN PEEL (Garcinia mangostana L.) AS CALCIUM CARBONATE SCALE INHIBITOR

In this research, it has been conducted the participation of mangosteen peel (Garcinia mangostana L.) extract in the calcium carbonate (CaCO3) growth solution to a green inhibitor of CaCO3 scale establishment utilizing unseeded technique at various concentrations of calcium carbonate 0.075, 0.100, and 0.125 M and concentration ranges of inhibitor added were around 0, 50, 150, and 250 ppm. Analysis of functional groups contained in mangosteen peel extract was performed by infrared (IR) spectrophotometer. The result shows that the extract of mangosteen peel may be applied as a green inhibitor to block CaCO3 scale formation with the highest Inhibitor Effectivity Percent (IEP) in blocking the CaCO3 deposit formation of 95.68% at the condition of calcium carbonate growth solution of 0.100 M and the mangosteen peel extract concentration added of 250 ppm. The results based on a qualitative analysis using Scanning Electron Microscope (SEM) showed that calcium carbonate size without the addition of inhibitors is bigger than the addition of inhibitors.

Pomegranate Peel Plant Extract as Potential Corrosion Inhibitor for Mild Carbon Steel in a 1 M HCl Solution

Herein, Pomegranate Peel plant extract was assessed as a low-cost, green and efficient corrosion inhibitor for mild carbon steel in 1 M hydrochloric acid solution using weight loss, potentiodynamic polarisation, an atomic absorption Spectroscopy test, surface roughness test and surface studies by optical microscopy (LOM). Increasing Pomegranate Peel extract concentration increases the charge transfer resistance as a result of the adsorption of Pomegranate Peel extract on the mild carbon steel surface. The polarisation results showed the mixed-type inhibition behaviour of the studied extract with an inhibition efficiency (%IE) of 90.193% achieved with the addition of 4% vol. of Pomegranate Peel plant extract. The adsorption isotherm model of Pomegranate Peel plant extract on a mild carbon steel surface followed the Langmuir adsorption isotherm in a HCl solution. The inhibition mechanism of Pomegranate Peel plant extract was explained according to the increase in the IE% with concentration and the activation parameters which suggested significant chemisorption of the Pomegranate Peel plant extract on the mild carbon steel surface. LOM studies confirmed the formation of a protective layer of Pomegranate Peel plant extract on a mild carbon steel surface. Results obtained by different techniques showed good agreement that confirm the potential use of Pomegranate Peel plant extract as a corrosion inhibitor for mild carbon steel in an acidic media.

Storage time evaluation of a residue from wine industry as a microencapsulated corrosion inhibitor for 1 M HCl

The effect of a residue from wine industry was investigated as a corrosion inhibitor for API P110 steel in hydrochloric acid. The extract was characterized using Fourier-transform infrared spectroscopy (FTIR), hydrogen nuclear magnetic resonance (1H NMR) and chromatography. The influence of temperature (303–333 K) and grape peel extract concentration were studied using gravimetric and electrochemical experiments. The coupon surfaces were evaluated using microscopy techniques, FTIR-ATR and the contact angle. The by-product exhibited high weight loss efficiencies at 303 K with 4.0 g/L of the extract (83.81%) even after storage. The inhibition increased with the addition of an inorganic enhancer, indicating a synergistic effect between the active compounds and maximum efficiency of 94.48%. Polarization tests indicated that the inhibitor adsorbs on anodic and cathodic regions. The surface characterization techniques confirmed the formation of an organic film and a less attacked surface was observed for the inhibited system.

Biosynthesis of silver nanoparticles using citrus sinensis peel extract and their application as antibacterial agent

Silver nanoparticles (Ag-NPs) have attracted huge importance due to their distinctive chemical, biological and physical properties. Silver nanoparticles are widely synthesized by the chemical method, which involves the use of toxic chemicals which affects its applications. The bio-reduction method, in comparison with chemical method is more economic and eco-friendly. In the present work, the bio-based production of Ag-NPs was done by using peel extract of orange (citrus sinensis), which played a role of reducing and stabilizing agent. The biosynthesis of silver nanoparticles was optimized by one factor at a time (OFAT) with respect to peel extract concentration, silver nitrate concentration and reaction temperature. The green synthesized silver nanoparticles were characterized by UV-visible spectroscopy, Fourier transforms infrared (FT-IR) spectroscopy, Scanning electron microscopy (SEM) and X-ray diffraction (XRD). Disk diffusion method was used for the study of antibacterial activity of the bio-synthesized silver nanoparticles against the bacteria Escherichia coli and Staphylococcus aureus. The results showed that at a peel extract concentration of 6%, the temperature of 60oC and silver nitrate concentration of 0.1M, the synthesis of Ag-NPs was effective. The orange peel synthesized Ag-NPs showed effective antibacterial activity against both bacteria. However better activity was observed against bacterium Staphylococcus aureus. The results confirmed the synthesis of Ag-NPs using peel extract of citrus sinensis and its role as antibacterial agent.

Antibacterial Activity Test of Ethanol Extract Pineapple (Ananas comosus (L.) Merr.) Peel against Growth of Propionibacterium acnes

Pineapple peel (Ananas comosus (L.) Merr.) is waste from the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Propionibacterium acnes. The pineapple peel extract is made by using the extraction method in the form of maceration. The method used in the inhibitory test using the three replication samples in each treatment group. The sample consisted of 10 treatment groups ie pineapple peel extract concentration 12.5%, 25%, 37.5%, 50%, 62.5%, 75%, 87.5%, and 100%, as well as positive and negative control. The results obtained from pineapple peel screening contain flavonoid and saponin compounds. The data analysis shows that pineapple peel extract concentrations of 50%, 62.5%, 75%, 87.5%, and 100% had inhibitory zones with the medium-strong category while clindamycin as the control has a strong inhibition zone. The conclusion of this research proves that pineapple peel extract has antibacterial power to P. acnes with effective concentration is 100% with the strong category.