Computer Program For Analysis Research Articles

Effect of artificial aging and different surface finishing protocols on the flexural strength and surface hardness of a photopolymer for manufacturing monolithic polychromatic complete dentures using PolyJet 3D printing.

This study evaluated the effect of thermocycling and three different surface finishing protocols on the flexural strength and surface hardness of a novel photopolymer intended for manufacturing monolithic polychromatic dental prostheses using PolyJet 3D printing. A total of 90 specimens were manufactured using a photopolymer for 3D printing monolithic polychromatic dental prostheses using PolyJet technology (TrueDent; Stratasys USA). The specimens were divided into three groups (n=30) according to the surface finishing protocol used: The control group Pumice+Moldent (Pumice), Pumice+Optiglaze (Optiglaze), and Polycril+Moldent (Polycril). Half of the specimens of each group (n=15) were subjected to 5000 thermocycles (Thermocycling Unit OMC350TSX; Odeme Dental Research, Santa Catarina, Brazil), The other half was stored in distilled water at room temperature for 7 days before testing. The flexural strength of the specimens was assessed in a universal testing machine (MTS Sintech ReNew; MTS Systems Corp, Aiden Prairie, MN), and the Vicker's surface hardness was evaluated with a microhardness tester (Micro indentation Hardness Tester LM247AT; Leco Instruments Ltd, Ontario, Canada). The resulting data was analyzed using two-way ANOVA tests, and Fisher's protected least significant differences (α=0.05) in a professional statistical analysis computer program (SAS v9.4, SAS Institute, Cary, NC) RESULTS: The two-way ANOVA tests suggested a statistically significant effect of thermocycling and the surface finishing protocol on the flexural strength (p=0.01) but without significant interaction between both independent variables (p=0.18). The post hoc analysis revealed no significant differences in the flexural strength between groups without thermocycling (p>0.05). Thermocycling decreased the flexural strength of all groups (p<0.05), and the Optiglaze group exhibited significantly higher flexural strength than the Polycril and Pumice groups after thermocycling (p<0.01). Regarding the surface hardness, the two-way ANOVA indicated a significant 2-way interaction between thermocycling and the surface of the finishing protocol (p=0.01). The post hoc analysis showed that the Optiglaze group had significantly higher hardness than the other groups, both before and after thermocycling (p<0.01) After thermocycling, a significant decrease in surface hardness was observed in the Polycril and Pumice groups (p<0.01). Surface finishing protocols and artificial aging can affect the surface hardness and flexural strength of the dental prostheses manufactured using the photopolymer studied. Careful polishing and surface finishing are required to ensure favorable clinical performance. Coating with a photopolymerizable glaze material seems to be a favorable surface treatment for monolithic polychromatic complete dentures fabricated using PolyJet 3D printing.

Hyperbaric Treatment Stimulates Chaperone-Mediated Macroautophagy and Autophagy in the Liver Cells of Healthy Female Rats.

The role of autophagy goes far beyond the elimination of damaged cellular components and the quality control of proteins. It also cleanses cells from inclusions, including pathogenic viruses, and provides energy-forming components. The liver, which is an organ with increased metabolism, is made up of cells that are particularly vulnerable to damage. Therefore, detoxification of liver cells in the process of autophagy has become a very important issue clinically. The aim of this study was an immunohistochemical evaluation of proteins activated in rat liver cells at different stages of hyperbaric autophagy. The rats used for the study were randomly divided into six equivalent groups-three control groups and three experimental groups. Animals from the experimental groups were subjected to hyperbaric treatment in a hyperbaric chamber, with a pressure of 1.6 ATA for 120 min. They breathed atmospheric air. Rats were decapitated within 5 or 10 days after removal from the chamber. Immunohistochemical reactions with beclin 1, LC3B, RAB7, and HSC73 proteins were carried out on preparations made from liver slices. A three-step labeled streptavidin-biotin detection method of paraffin blocks (LSAB three-step) was used for immunohistochemical research. The results were evaluated using computer programs for morphometric analysis of microscopic images by calculating the mean surface areas occupied by a positive immunohistochemical reaction in individual groups for all antibodies tested. Increased closure of substrates in the autophagosome (beclin 1) induced late endosome transport and accelerated autophagosome maturation process (RAB7). Furthermore, a larger number of autophagosomes (LC3B) was observed in liver cells immediately after the cessation of hyperbaric activity; however, this decreased after 5 days. During this time, chaperone-mediated autophagy (HSC73) was observed on a larger scale. This means that increased macroautophagy induced by hyperbaric treatment weakens with time that has elapsed since the cessation of high pressure, whereas similarly induced chaperone-mediated autophagy intensifies over time.

A study of the impact of entrance space on indoor air quality in vernacular dwellings in desert areas during sandstorms

Alxa League, located in the western part of Inner Mongolia, China, frequently suffers from sandstorms. Such dusty conditions result in sharp increases in respirable particulate matter (PM10) concentration in outdoor and indoor environments, posing a significant health risk to local inhabitants. Vernacular dwellings in this area feature a specific floor plan that includes an entrance space to safeguard indoor air quality during sandstorms while being compatible with the local climate. This study utilises CONTAM, a multizone indoor air quality and ventilation analysis computer program, and field measurements to quantitatively evaluate the effectiveness of the entrance space in protecting indoor air quality against ambient PM10 pollution under both dusty and normal conditions. The simulation results reveal that the entrance space can effectively mitigate PM10 pollution in the middle room, lowering the average concentration from 47.0 μg/m3 to 37.5 μg/m3 during dust periods. However, PM10 pollution may increase in the entrance space, reaching an average concentration of up to 70.0 μg/m3. Experimental outcomes align with the simulated results. Given that construction activities exacerbate desertification and frequent sandstorms, the above findings help identify the optimal design strategies for energy-efficient green vernacular dwellings in the targeted desert area, promoting environmental harmony and addressing climate change challenges.

Exact Mathematical Solution for Maximum Transient Offtracking Calculation of a Single-Unit Vehicle Negotiating Circular Curves

The low-speed turning maneuverability of vehicles is closely related to a well-known offtracking phenomenon which occurs when the rear wheels of a turning vehicle deviate towards the inside of a horizontal curve. Although numerous mathematical models and computer programs for vehicle swept path analysis have been developed in the past, only a few of them can calculate the maximum transient offtracking of a turning vehicle, yet with limited accuracy. The authors were motivated by this fact to find a new mathematical solution for maximum transient offtracking calculation of a single-unit vehicle when negotiating circular curves. In the first stage, a transcendental equation defining vehicle maximum transient offtracking position is derived and numerically solved by Python 3.10.12. In the second stage, the polynomial regression model predicting accurate numerical solutions of the transcendental equation with the desired level of accuracy was developed and tested. The new calculation method is simple enough to simply take the vehicle datum length, circular curve radii, and turn angle, while instantly producing the maximum transient offtracking value, without the need to draw any of the vehicle movement trajectories.

HISTOCHEMICAL AND IMMUNOHISTOCHEMICAL FEATURES OF DIFFERENTIATED TROPHOBLAST IN CHORIONIC VILLI OF THE PLACENTA IN PRETERM LABOR

The importance of studying the histochemical and immunohistochemical features of the diff erentiated trophoblast in chorionic villi of the placenta in preterm labor is determined by the threatening nature of this condition for both mother and fetus, as well as its high prevalence and serious consequences for the health of both. The understanding of the damage to the trophoblast of chorionic villi in the placenta can be expanded by histochemical and immunohistochemical methods, which allow the assessment of the concentration of specifi c marker molecules in one way or another.Objective. To determine certain histochemical and immunohistochemical characteristics of proteins in the trophoblast of theintermediate and terminal chorionic villi of the placenta in preterm labor.Material and Methods. The obtained material (30 placentas from preterm deliveries and 30 placentas from normalpregnancies) was fi xed for 20-24 hours in 10 % neutral formalin solution buff ered in Lilly’s phosphate buff er. After tissue removal, the placental tissue was dehydrated in an ascending ethanol series and embedded in paraffi n at a temperature of approximately 58 °C. Serial histologic sections were cut at 5.0 μm thickness using an MS-2 sliding microtome. After deparaffi nization, histological sections were stained with hematoxylin and eosin, histochemical methods for total protein with bromophenol blue according to Bonhéme, and immunohistochemical techniques according to the manufacturer’s protocols (Dako, Denmark). In particular, immunohistochemical reactions were performed with monoclonal antibodies against trophoblast hormone- placental lactogen and placental alkaline phosphatase. Visualization of primary antibodies was performed using the Dako polymer visualization system with diaminobenzidine as chromogen (resulting in brown staining of the sites of studied antigens). In addition to the descriptive method of histopathologic research, computer morphometry of digital microphotographs of histologic sections was performed using a Delta Optical Evolution 100 microscope and an Olympus SP550UZ digital camera. Digital copies of the images were processed using a legitimate copy of the ImageJ v1.52f computer program developed for histometric studies (National Institutes of Health, USA). Specifi cally, the evaluation of staining intensity (optical density) was performed on digital microphotographs using the method of computer microdensitometry. For this purpose, a microprobe method was used to obtain a computer brightness value in an 8-bit analysis system with 256 gray levels – from black (0) to white (255).The obtained values were then transformed into relative optical density values (r.OD) by logarithmic transformation (naturallogarithm method). The relative optical density value ranges from 0 (absolute transparency of the object) to 1 (absolute opacity of the object). The obtained digital data were processed using statistical analysis methods. A legitimate copy of the statistical analysis computer program PAST v4.14 was used, with a preliminary check for normal distribution using the Shapiro- Wilk test. Since, according to this test, the hypothesis of normal distribution was not rejected for the statistical samples studied (at p=0.05), parametric methods of statistical analysis were applied: calculation of the mean and its standard error, Student’s t-test (two-tailed, unpaired). In addition, the non-parametric Mann- Whitney test was used for the reliability of the conclusions. The research was conducted as part of the scientifi c research project «Preservation and Restoration of Reproductive Health in Women and Girls with Obstetric and Gynecological Pathology» at the Department of Obstetrics and Gynecology of Bukovinian State Medical University (state registration number 0121U110020, duration 2021-2025).Results. Microscopic examination of histological sections stained with hematoxylin and eosin did not reveal any diff erencesin the structure of chorionic villus trophoblast in the placenta of preterm labor compared to normal pregnancy. However,histochemical and immunohistochemical methods of investigation revealed a number of features in the trophoblast of chorionic villi, where fundamental events related to substance exchange occur – intermediate immature, intermediate mature, terminal villi, including terminal «specialized villi».Conclusions. According to the obtained histochemical and immunohistochemical data, in preterm labor, compared to normalpregnancy, no changes are observed in the trophoblast of intermediate immature villi, while in intermediate mature and terminal villi, there is a decrease in histochemical staining for total protein and immunohistochemical staining for specifi c trophoblast proteins – placental lactogen hormone and placental alkaline phosphatase enzyme.

IQual: a new computer program for qualitative phase analysis with efficient search–match capability

iQual is a new computer program developed for qualitative phase analysis using powder diffraction data. It is based on a new database named Crystal_db, derived from the latest Crystallography Open Database. Crystal_db has been created with organized functional modules and optimized index structures, greatly enhancing the database's search efficiency. The iQual program offers users a wide range of querying capabilities and convenient visualization features. In addition to providing an efficient interactive interface, the program combines with the optimized database to enable efficient searching for and finding of the data entries that best match the experimental data for qualitative analysis of X-ray diffraction patterns. The highlight of this search–match method lies in an effective two-step approach that makes full use of the database structure. A preliminary screening is adopted, based on the five strongest diffraction peaks of each candidate phase, prior to scoring the candidate phases. Matrix operations in both screening and scoring processes enhance the program's efficiency.

Influence of perfluoroorganic emulsion on morphometric parameters of the liver in a systemic inflammatory response (experimental study)

The objective was to study the effect of drug «Oxyphtem»1 on liver morphometric parameters in a systemic inflammatory response.Materials and methods. The experimental study was carried out on male Wistar rats (n = 26). The rats of the experimental group were injected with drug «Oxyphtem» intravenously once. Daily observation was carried out during14 days. Rats were taken out of the experiment on the 15th day under light ether anesthesia. Liver samples were fixed in 10 % neutral formalin in phosphate buffer for 24 hours. Histological preparations were studied using the Measure Pixels image analysis computer program based on a Leica 2000 light microscope.Results. In the intact group of rats, no violations of the liver parenchyma were detected: hepatocytes had clear boundaries, the lamellar structure was preserved and sinusoidal capillaries were not dilated. With the development of the systemic inflammatory response in the liver of rats of the control group, expansion and blood filling of the central veins and sinusoids, violation of the structure of the liver plates, and perinuclear edema of hepatocytes were noted. In the experimental group of rats with the use of drug «Oxyphtem», the preservation of the structure of the liver plates was observed, binuclear hepatocytes were found, and the sinusoids were not expanded. We hypothesize that hepatocyte proliferation and the increase in binuclear hepatic cells were indicative of the regenerative response to systemic inflammatory damage and metabolic demand.Conclusion. The use of drug «Oxyphtem» under conditions of the experimental systemic inflammatory response increases reparative regeneration and adaptation of the liver.

ANALISIS PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN PASIEN DI PUSKESMAS GAYAMAN KABUPATEN MOJOKERTO

Patient satisfaction is very important and is the most frequently discussed issue. Patient satisfaction at the health centre itself depends on the subjectivity of the patient. The purpose of this study was to analyse the effect of service quality on patient satisfaction at Gayaman Health Centre, Mojokerto Regency. This research includes quantitative research where this research includes survey research conducted in May - August 2023. The population in this study were all patients/families of patients at Gayaman Health Centre, Mojokerto Regency who were registered at inpatient and outpatient counters. The sample used was accidental sampling, the sampling technique used was Accidental Sampling. The validity test tests whether the question is valid or not can be done through the Excel Statistical Analysis computer program, while the reliability test has a Cronbach's Alpha value above 0.60. The simple regression test result a = 3.266 is a constant value, which means that if X is considered 0, the patient satisfaction value is 3.266, b = 0.425 which is positive. Based on the description and analysis, it is known that service quality has a positive effect on patient satisfaction. Judging from the validity test of service quality on consumer satisfaction (patients) meets the requirements because the correlation value has a value above 0.2732. most patients / families of patients agree (satisfied) in terms of physical appearance (tangibles) with a percentage of 48%, reliability (reliability) 48%, and assurance and empathy (empathy) 44%.

An Object-Oriented Computer Program for Structural Reliability Analysis (BI): Components and Methods

An Object-Oriented Computer Program for Structural Reliability Analysis (BI): Components and Methods

АКУСТИЧКЕ КАРАКТЕРИСТИКЕ ГЛАСА И ГОВОРА ОДРАСЛИХ ОСОБА СА АТАКСИЧНОМ ДИЗАРТРИЈОМ

The aim of this study was to determine the acoustic characteristics of voice and speech in adults with ataxic dysarthria, and to examine the extent to which they differ from those of typical speakers. The sample consisted of 30 patients with ataxic dysarthria, ages 21 through 82 (M = 56.07). Using the computer programme for multidimensional voice analysis (MDVP), the individual values of 10 acoustic voice parameters were determined for each sex. Additionally, the programme provided the frequency values of the first two formants for all five vowels of the Serbian language, based on the participants’ reading of the Balanced Text. The results of the analysis showed statistically significant differences in the values of the acoustic parameters between the participants with ataxic dysarthria and the reference values valid for typical speakers, which were generated by the MDVP. These differences were observed in parameters indicating voice frequency variability (F0, Fhi, Flo, STD, Jitt, vF0), voice intensity variability (Shim and vAm), and the presence of voice interruptions (DVB) and voiceless periods (DUV). Furthermore, a statistically significant difference was found between participants with ataxic dysarthria and typical speakers in the second formant (F2) of the vowels /E/ (p &lt;0.01), /I/ (p &lt;0.01), and /U/ (p &lt;0.05). The significant deviations from the norms applicable to typical speakers indicate the substantial changes present in the voice and speech of individuals with ataxic dysarthria.

Analysis of Nursing Students' Nonverbal Communication Patterns during Simulation Practice: A Pilot Study.

Therapeutic communication, of which nonverbal communication is a vital component, is an essential skill for professional nurses. The aim of this study is to assess the possibility of incorporating computer analysis programs into nursing education programs to improve the nonverbal communication skills of those preparing to become professional nurses. In this pilot observational study, the research team developed a computer program for nonverbal communication analysis including facial expressions and poses. The video clip data captured during nursing simulation practice by 10 3rd- and 4th-grade nursing students at a university in South Korea involved two scenarios of communication with a child's mother regarding the child's pre- and post-catheterization care. The dominant facial expressions varied, with sadness (30.73%), surprise (30.14%), and fear (24.11%) being the most prevalent, while happiness (7.96%) and disgust (6.79%) were less common. The participants generally made eye contact with the mother, but there were no instances of light touch by hand and the physical distance for nonverbal communication situations was outside the typical range. These results confirm the potential use of facial expression and pose analysis programs for communication education in nursing practice.

HISTORICAL STYLISTICS IN RUSSIAN LINGUISTICS

The article presents an overview of the development of historical stylistics as one of the directions of Russian linguistics. The main works substantiating the appearance of historical stylistics are indicated, the stages of the formation of this linguistic direction are defined and characterized. The paper describes the distinctive features of each of these stages, identifies the genres of texts characterized from the standpoint of historical stylistics, establishes the features of the stylistic characteristics of written records. The paper provides examples of the most significant theoretical and practical studies carried out from the standpoint of historical stylistics, and indicates possible directions for further study of multi-genre texts in the historical and stylistic aspect. Research using computer programs for semantic text analysis and comparative studies of the stylistic organization of texts in closely related languages are indicated among the possible directions for the development of historical stylistics.

Effects of Shear Deformation on Flexural Response of Laminated Composite I-Beam

In this paper, a computational approach based on a kinematic model for laminated composite I-section beam is presented. The flexural behavior of laminated composite I-beams is analyzed by using Classical Lamination Plate Theory (CLPT) and the First Order Shear Deformation Theory (FSDT). Based on these theories, a computer programme for analysis of laminated I-beam has been developed in MATLAB. The comparison of results obtained using both theories has been made. It is shown that the shear deformation has significant effect on the deflection of the beam. Furthermore, the laminated I-beam is also modeled using ABAQUS software package for numerical results using different value of load applied at mid-span of the beam. Results obtained using ABAQUS are compared with results obtained with self developed computer program in MATLAB. It is observed that there is good correlation between results obtained from ABAQUS and the computer program before local failure such as buckling of flanges and web occur. Finally, the effect of various parameters such as width-tothickness ratio of flanges, depth-to-thickness of web, and span length-to-depth ratio of I-beam has been investigated. It is concluded that the effect of web depth-to-thickness ratio has little effect on the overall flexural response of I-beam while the width-to-thickness ratio of flanges has significant effect on the flexural response of composite I-beams.

NGS Analysis to Detect Mutation in Brain Tumor Diagnostic

Abstract: This study presents an integrated computational approach for analyzing protein sequences and their 3D structures. By leveraging the MMDB Macromolecular database, homologs of a protein sequence of interest are identified, and interactive visualization of their structural properties is provided. The computational alignment method, using BLASTP, allows for efficient determination of sequence similarities and identification of conserved regions among multiple protein sequences. COBALT is employed to refine sequence alignments and facilitate graphical analysis of sequence relationships. RASMOL, a computational analysis program, generates 2-D representations of protein-ligand complexes, enabling visual exploration of their interactions. ORF finder is used to identify coding regions in mRNA sequences, aiding in the prediction of protein-coding regions. The approach is applied to brain tumor diagnostics using human biological samples, exploring the structural properties of brain tumor-related proteins with the help of the 2RHU protein structure and PYMOL visualization software. Overall, this integrated computational framework offers a comprehensive toolkit for protein sequence analysis, structure visualization, and homology modeling, with potential applications in drug discovery, molecular biology, and medical diagnostics

Physical Education Teachers’ Reflection about their Learning in Post-Pandemic Era: A Mixed-Method Study

The purpose of the current study was twofold: (1) to explain teachers’ perception on the impacts of COVID-19 pandemic on teaching physical education and (2) to explore teachers’ reflexivity, including their post-pandemic teaching possibilities. Mixed-methods research with sequential explanatory design was utilized in this study. A number of 41 physical education teachers were recruited to participate in the study. The first phase was a quantitative method designed to collect survey data about the impacts of the pandemic on their teaching. A descriptive statistic was used to analyze the data. The result of the first phase facilitated the development of the second phase focusing on teachers’ reflection on their teaching. Four teachers were selected to participate in in-depth interviews. Data were analyzed thematically assisted by a computer program for qualitative data analysis, namely ATLAS.ti. Result showed that the pandemic had impacted on students’ motivations, teachers’ workload, learning objectives, face-to-face classrooms, learning process, and assessment. It has also been revealed that teachers identified advantages of getting new learning resources and development. These included teachers’ new skills of using technology for learning, increased creativity in teaching, and close collaboration with parents. The study concluded that the pandemic had impacts on the teaching PE as well as student learning. However, they eventually facilitated reflexivity on how PE learning would be in the future.

Trapalyzer: a computer program for quantitative analyses in fluorescent live-imaging studies of neutrophil extracellular trap formation.

Neutrophil extracellular traps (NETs), pathogen-ensnaring structures formed by neutrophils by expelling their DNA into the environment, are believed to play an important role in immunity and autoimmune diseases. In recent years, a growing attention has been put into developing software tools to quantify NETs in fluorescent microscopy images. However, current solutions require large, manually-prepared training data sets, are difficult to use for users without background in computer science, or have limited capabilities. To overcome these problems, we developed Trapalyzer, a computer program for automatic quantification of NETs. Trapalyzer analyzes fluorescent microscopy images of samples double-stained with a cell-permeable and a cell-impermeable dye, such as the popular combination of Hoechst 33342 and SYTOX™ Green. The program is designed with emphasis on software ergonomy and accompanied with step-by-step tutorials to make its use easy and intuitive. The installation and configuration of the software takes less than half an hour for an untrained user. In addition to NETs, Trapalyzer detects, classifies and counts neutrophils at different stages of NET formation, allowing for gaining a greater insight into this process. It is the first tool that makes this possible without large training data sets. At the same time, it attains a precision of classification on par with state-of-the-art machine learning algorithms. As an example application, we show how to use Trapalyzer to study NET release in a neutrophil-bacteria co-culture. Here, after configuration, Trapalyzer processed 121 images and detected and classified 16 000 ROIs in approximately three minutes on a personal computer. The software and usage tutorials are available at https://github.com/Czaki/Trapalyzer.

The Influence of “Green” Roofs on the Energy Efficiency of Residential Buildings in the City of Tula

The need to improve the thermal engineering characteristics of the enclosing structures of construction objects and the increasing interest of the state in the development of environmental policy increase the prospects for studying the technology of “green” roofs because they are capable to solve comprehensively issues of energy efficiency and environmental safety. The object of the study is modern technological solutions of “green” roofs, the subject of the study is the analysis of the thermo-physical properties of coatings using “green” roof systems, the objectives of the study include: justification of the need to implement the above systems in the current climatic conditions, market analysis of the solutions offered by leading manufacturers of “green” coatings, the implementation of comparative thermal engineering calculations, calculations of stationary and non-stationary heat transfer in the thickness of coating structures. In the course of the study, data from official statistics websites, publicly available satellite images of remote sensing and also mathematical analysis methods, including methods of correlation and regression analysis, forecasting trends based on the obtained indicators were used. To perform the calculations, the Excel software package and the ELCUT engineering analysis computer program that allows two-dimensional modelling in solving thermal problems were used. Statistical data on the provision of residents of the region with public green spaces have been formed and analysis of the environmental parameters of the territory was carried out with the creation of a correlation and regression model, also forecast values. The results of the temperature distribution fields for stationary and non-stationary heat transfer of two types of “green” roof construction are obtained, taking into account various parameters of finishing the inner surface of the coating. Statistical environmental data that was generated using mathematical analysis methods made it possible to determine the environmental risks of the region, to create a basis for further research on the territory of the Tula region. The energy efficiency indicators of various types of “green” roofs, obtained as a result of thermal engineering calculations, as well as the identified accumulation capabilities, allowed us to draw conclusions about the prospects for the introduction of “green” technologies and the need for further research in the field of energy conservation and thermal inertia of enclosing structures of construction objects.

Diabetes Self Management Education Assistance on The Quality of Life in Type 2 Diabetes Mellitus Patients

Patients with DM in the district. Rejang Lebong reached 382 cases, and 9 people died from this disease in 2020. Diabetes Self Management Education (DSME) is a program designed to provide understanding and skills in caring for DM sufferers daily at home. This subject of this study was to analyze the effect of DSME administration on the quality of life in type 2 DM patients in the PKM Perumnas area, Rejang Lebong district. This research is a quasi-experimental study with a pretest and posttest approach with a control group design. The sampling technique used consecutive sampling involving 30 respondents, divided into 15 respondents in the treatment group and 15 in the control group. Bivariate analysis in the form of a parametric test, namely the dependent t-test and independent t-test with ? = 0.05. Researchers use computer programs for data processing and statistical analysis. The mean quality of life for DM patients was 36.20 with a standard deviation of 10.79 and p = 0.000 &lt;0.05. This shows that after the intervention, there is an increase in the quality of life of DM patients by 36.20. There is an effect of Diabetes Self-Management Education (DSME) on the Quality of Life of Diabetes Mellitus (DM) Patients in Kab. Rejang Lebong in 2022. Education is essential for patients to change their behaviour and self-management independently to improve the quality of life of DM patients.

Qualitative public health research published in Colombian biomedical journals between 2011 and 2021

Introduction: Qualitative research seeks to understand the meaning and perspective of individuals and investigates considering the context. This paradigm allows the interpretation and study of phenomena from their own complexity. In public health, qualitative research has gained ground, as it allows the study of subjective aspects of the health-disease process. Objective: To describe and analyze qualitative research on health issues published in Colombian journals between 2011 and 2021. Materials and methods: A descriptive study on qualitative health research published in Colombian journals between 2011 and 2021 was carried out. Results: Eighty-one articles were included. The journal with the highest number of publications was the Revista de Salud Pública (44.4%). The year with the highest production corresponded to 2019 and the main design was the fundamental theory (17.3%). In 79% of the articles, women were the main author and nursing was the most frequent profession of undergraduate training. The most frequent topic was HIV/AIDS (12.3%), followed by cancer (11.1%). In 24.6% of the studies, a software was used for the analysis. Conclusions: Qualitative research in public health has had a variable dynamic in scientific production between 2011 and 2021. Despite its benefits, the adoption of computer programs for qualitative analysis is rare. Nursing stands out as the area that concentrates the largest number of qualitative studies in public health with contributions on topics such as COVID-19 and HIV/AIDS.

Open-source simulation of strongly-coupled fluid-structure interaction between non-conformal interfaces

Design code-based “life-safety” requirements for structural earthquake and tsunami design offer reasonable guidelines to construct buildings that will remain standing during a tsunami or seismic event. Much less consideration has been given to assessing structural resilience during sequential earthquake and tsunami multi-hazard events. Such events present a series of extreme loading scenarios, where damage sustained during the earthquake influences structural performance during the subsequent inundation. Similar difficulties exist with respect to damage sustained during tropical events, as wind and fluid loading may vary with structural response or accumulated damage. To help ensure critical structures meet a “life-safety” level of performance during such multi-hazard events, analysis software capable of simulating simultaneous structural and fluid dynamics must be developed. To address this gap in understanding of non-linear fluid-structure-interaction (FSI), an open-source tool (FOAMySees) was developed for simulation of tsunami and wave impact analysis of post-earthquake non-linear structural response of buildings. The tool is comprised of the Open-source Field Operation And Manipulation software package and OpenSeesPy, a Python 3 interpreter of OpenSees. The programs are coupled via preCICE, a coupling library for partitioned multi-physics simulation. FOAMySees has been written to work in a Linux OS environment with HPC clusters in mind. The FOAMySees program offers a partitioned conventional-serial-staggered coupling scheme, with optional implicit iteration techniques to ensure a strongly-coupled two-way FSI solution. While FOAMySees was developed specifically for tsunami-resilience analysis, it may be utilized for other FSI applications with ease. With this coupled Computational Fluid Dynamics (CFD) and Finite Element Analysis (FEA) program, tsunami and earthquake simulations may be run sequentially or simultaneously, allowing for the evaluation of non-linear structural response to multi-hazard excitation.