Abdominal CT (Computed Tomography) scans are crucial for diagnosing a wide range of abdominal conditions by providing detailed images of the abdominal organs. The aim of this study is to develop and validate a novel timing equation for predicting optimal contrast medium enhancement in abdominal CT procedures. Utilizing a quantitative research design, data was retrospectively collected from 155 patients who underwent CT scans with contrast media, focusing on variables such as age, gender, weight, creatinine levels, and injection parameters. Statistical analysis, including multi-linear regression and ANOVA, was conducted to derive predictive equations for arterial, venous, and delayed times. The results indicated that Location of the cannula significantly influence arterial time, age is significantly influence venous enhancement time, while weight was the only significant predictor of delayed time, demonstrating the need for patient-specific timing in CT scans. In conclusion, the proposed timing equation could enhance diagnostic accuracy and patient care by optimizing contrast enhancement in abdominal CT procedures.