Comprehensive Therapy Group Research Articles

Curative effect of hydrogen peroxide combined with silver ion disinfection on pelvic floor dysfunction.

Pelvic floor dysfunction (PFD) is related to muscle fiber tearing during childbirth, negatively impacting postpartum quality of life of parturient. Appropriate and effective intervention is necessary to promote PFD recovery. To analyze the use of hydrogen peroxide and silver ion disinfection for vaginal electrodes in conjunction with comprehensive rehabilitation therapy for postpartum women with PFD. A total of 59 women with PFD who were admitted to the hospital from May 2019 to July 2022 were divided into two groups: Control group (n = 27) received comprehensive rehabilitation therapy and observation group (n = 32) received intervention with pelvic floor biostimulation feedback instrument in addition to comprehensive rehabilitation therapy. The vaginal electrodes were disinfected with hydrogen peroxide and silver ion before treatment. Intervention for both groups was started 6 weeks postpartum, and rehabilitation lasted for 3 months. Pelvic floor muscle voltage, pelvic floor muscle strength, vaginal muscle voltage, vaginal muscle tone, pelvic floor function, quality of life, and incidence of postpartum PFD were compared between the two groups. Before comprehensive rehabilitation treatment, basic data and pelvic floor function were not significantly different between the two groups. After treatment, the observation group showed significant improvements in the maximum voltage and average voltage of pelvic floor muscles, contraction time of type I and type II fibers, pelvic floor muscle strength, vaginal muscle tone, vaginal muscle voltage, and quality of life (GQOLI-74 reports), compared with the control group. The observation group had lower scores on the pelvic floor distress inventory (PFDI-20) and a lower incidence of postpartum PFD, indicating the effectiveness of the pelvic floor biostimulation feedback instrument in promoting the recovery of maternal pelvic floor function. The combination of the pelvic floor biostimulation feedback instrument and comprehensive rehabilitation nursing can improve pelvic floor muscle strength, promote the recovery of vaginal muscle tone, and improve pelvic floor function and quality of life. The use of hydrogen peroxide and silver ion disinfectant demonstrated favorable antibacterial efficacy and is worthy of clinical application.

Effects of mind-regulating acupuncture on pain, negative emotion and sleep quality in patients with postherpetic neuralgia： a randomized controlled pilot trial.

To observe the effect of mind-regulating acupuncture on pain intensity, sleep quality, negative emotion in patients with postherpetic neuralgia (PHN), and evaluate the clinical effect of mind-regulating acupuncture combined with surrounding needling and heavy moxibustion at Ashi points (Extra) in treatment of PHN. The patients with PHN were randomly divided into a control group (35 cases, 2 cases dropped out) and a comprehensive therapy group (35 cases). The patients in the control group were treated with surrounding needling and heavy moxibustion at Ashi points. In the comprehensive therapy group, the mind-regulating acupuncture therapy was delivered besides the treatment as the control group. The treatment was given once daily, one course of treatment was composed of 6 days and 2 courses were required in the 2 groups. Before and after treatment, the pain conditions were assessed using pain rating index (PRI), visual analogue scale (VAS) and present pain intensity (PPI), the negative emotions were assessed using Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD), and the sleep quality with Pittsburgh sleep quality index (PSQI). One week before and one week after treatment, the average sleep time was recorded. The therapeutic effect of 2 groups was evaluated. The effective cases of 2 groups were followed up in 2 months after treatment completion and the recurrence of neuralgia was recorded. There were no statistical differences in the above indicators between the 2 groups before treatment. After 2 courses of treatment, the scores of PRI, VAS, PPI, HAMA, HAMD and PSQI were reduced when compared with those before treatment in the patients of the 2 groups (P<0.05), and the average sleep time was increased (P<0.05). The scores of PRI, VAS, PPI, HAMA, HAMD and PSQI in the comprehensive therapy group, as well as the average sleep time were all improved when compared with those of the control group (P<0.05). The total effective rate in the comprehensive therapy group (34/35, 97.14%) was higher than that of the control group (27/33, 81.82%, P<0.05) and the recurrence rate was lower (［2/34, 5.88%］vs［8/27, 29.63%］, P<0.05). The combination of mind-regulating acupuncture with surrounding needling and heavy moxibustion at Ashi acupoint can effectively relieve PHN. Compared with the traditional surrounding acupuncture in pain area combined with moxibustion at Ashi points, this comprehensive therapy is more effective for ameliorating pain intensity, improving sleep quality and reducing negative emotions. It is also effective for declining the recurrence.

Comparison of the Effect of Therapeutic Exercise Protocol With and Without Kinesiotype and Manual Therapy on Pain and Disability and Muscle Function of Men With Cervicogenic Headache

Background and Aims Headache is one of the most common problems in adults and almost 47% of the world's population suffer from some kind of headache. High percentage of these headaches come from neck muscles these are called cervicogenic headaches. The purpose of this study is Comparison of the effect of comprehensive therapeutic protocol with and without manual treatment and kinesiotaping on pain and disability, postural and electrical activity of some neck muscles in men with non-traumatic cervicogenic headache. Methods 43 men aged 35 to 55 years with non-traumatic cervicogenic headache were selected for this study and randomly divided into four groups.Forward head angle, pain and disability and power of neck superficial muscle activation measured by using the photogrammetry, neck pain and disability scale (NPDS) and surface electromyography respectively in pre-test and after six weeks in post-test. Statistical methods, Shapiro-wilk and then repeated measures ANOVA and one-way ANOVA and paired t-test, repeated measure variance and finally and Bonferroni were used (α≤0.05). Results The results showed a significant decrease in pain and disability, forward head angle and also a decrease in the activity of the superficial neck muscles in the experimental groups after six weeks of intervention. (P=0.00). Comparing the above three experimental groups, the comprehensive exercise therapy group with manual therapy had the highest statistical significance in reducing pain and disability, reducing the angle of head forward and reducing the activity of superficial neck muscles. (P=0.00). Conclusion comprehensive exercise therapy intervention with manual therapy had the greatest effect on improving the symptoms of men with non-thromatic cervicogenic headache.

Clinical Observation on the Prevention and Treatment of Juvenile Mild Myopia with Traditional Chinese Medicine Comprehensive Therapy

Objective: To observe the clinical effect of traditional Chinese medicine on the prevention and treatment of juvenile mild myopia. Methods: One hundred and twenty cases of juvenile mild myopia were randomly divided into six groups, with 20 cases in each group: western medicine group, ultrasonic group, acupuncture group, auricular point group, traditional Chinese oral decoction group, and traditional Chinese medicine comprehensive therapy group. The therapeutic effects of the treatment administered to the six groups were compared. Result: In the post-treatment and follow-up stages, the visual acuity of the traditional Chinese medicine comprehensive therapy group significantly improved along with reduced diopter compared to the other groups (p &lt; 0.05). However, the axial length of the six groups had no significant change compared with that before treatment (p &gt; 0.05). There were no adverse reactions in any of the patients. Conclusion: In the treatment of juvenile mild myopia, traditional Chinese medicine comprehensive therapy has good therapeutic effect without any adverse reactions; thus, it is worthy of clinical promotion.

Autologous Shuffling Lipo-Aspirated Fat Combined Mechanical Stretch in Revision Rhinoplasty for Severe Contractures in Asian Patients.

A severely contracted nose is a common occurrence. Intraoperative expansion is not sufficient to soften the severely constricted nasal envelope, which poses challenges in revision rhinoplasty. In recent years, adjuvant therapies, including nasal fat grafting and cell component injection, are applied before revision rhinoplasty to soften the nasal envelope. Herein, autologous shuffling lipo-aspirated fat and manual mechanical stretch were combined as adjuvant therapy before revision rhinoplasty. A total of 24 patients with severe nasal contracture were included in this study. Of these, 8 received autologous shuffling lipo-aspirated fat and manual mechanical stretch before revision rhinoplasty (comprehensive therapy), 8 underwent mechanical stretch and revision rhinoplasty, and 8 patients underwent only revision rhinoplasty. The objective and subjective outcome assessment was processed in the follow-up period of 6 months. Nasal length, nasal tip projection, nasofrontal angle, and nasolabial angle were measured, and potential complications were assessed. All 24 patients underwent a successful revision rhinoplasty. In the comprehensive therapy group, no patient had postoperative wound infection and defect of the nasal column mucous. The comprehensive treatment group had the most significant improvement in nasal length and nasal tip projection, and the nasolabial angle was the closest to 90°, which indicated the most effective nasal revision and aesthetic contour. The adjuvant therapy combines autologous shuffling lipo-aspirated fat and manual mechanical stretch before revision rhinoplasty could effectively improve the surgical outcome and decrease the postoperative complications regarding severe nasal contractures. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Comparative analysis of the effectiveness of the comprehensive antioedema therapy versus multilayer bandaging in lower limbs lymphoedema treatment.

IntroductionTreatment of patients with lymphoedema is time-consuming, labour-intensive, and is frequently associated with considerable costs. In Poland, patients with lower limb lymphoedema encounter major problems with access to the comprehensive antioedema therapy. In many cases treatment is limited only to the compression therapy alone or various forms of lymphatic drainage without compression support. This situation makes it difficult to obtain satisfactory treatment results.AimTo compare the effects of lower limb lymphoedema treatment by means of the multilayer compression therapy alone and the comprehensive antioedema therapy.Material and methodsThirty-four women aged 50–80 years with stage 2 primary lymphoedema of the lower limbs were treated. The therapy was carried out at the Daily Rehabilitation Centre of the Palium Hospice in Poznan. The patients were treated for 2 weeks with the application of the multilayer compression therapy alone (group 1) or the comprehensive antioedema therapy (group 2).ResultsAfter 2 weeks, the volume of treated limbs decreased by 652.9 ±712.2 ml (15.9%) in group 1 and by 523.1 ±448.1 ml (11.2%) in group 2. The range of observed changes was comparable (p = 0.77).ConclusionsAlthough the oedema reduction was significant in both groups, no differences in the degree of the reduction were observed, which depends on the application of both therapeutic techniques. In the short-term treatment, no beneficial effect of the manual lymphatic drainage on the increase of the volume reduction of lower limbs affected by lymphoedema was observed.

A comprehensive reconstruction strategy for moderate to severe faciocervical scar contractures.

The focus of treatment of faciocervical scar contractures includes cervical reconstruction and elimination of hypertrophic scars. Unfortunately, most previous studies have neglected the esthetic appearance of scars. In this study, we tried to combine surgical therapy and ultrapulse fractional CO2 laser (UFCL) to eliminate facial scars while restoring neck reconstruction and to establish the optimal conventional management for faciocervical contracture. Thirty-eight individuals were enrolled and divided into two groups. After received cervical release surgeries, comprehensive UFCL therapy group received treatment of UFCL at 3-month intervals, silicone sheets, and pressure garments, while another group only received treatment of silicone sheeting and compression. Twelve months after the termination of therapy, faciocervical scars of both two groups were assessed by two uninvolved physicians according to the Vancouver Scar Scale (VSS), and patients' satisfaction survey was also recorded by the study participants using a patient four-point satisfaction scale. Thirty-six patients completed the treatment and follow-up. The results show that the VSS scores of both two groups decreased after 12months, but comprehensive UFCL therapy group dropped more significantly than the conventional treatment group at follow-up session, which was statistically significant (P < 0.001), and the patient satisfaction was higher than that of the conventional treatment group. This comprehensive treatment combined of surgery, UFCL, silicone sheets, and pressure garments works as an effective and esthetic reconstruction for moderate to severe postburn faciocervical scar contractures.

Intestinal dysfunction of spinal cord injury treated with tongdu tiaoshen moxibustion: a randomized controlled trial

To compare the clinical effect on intestinal dysfunction of spinal cord injury (SCI) between the comprehensive therapy of tongdu tiaoshen moxibustion (moxibustion for opening the governor vessel and regulating the spirit) and rehabilitation training and the simple treatment with rehabilitation training. A total of 60 patients with intestinal dysfunction of SCI were randomized into a comprehensive therapy group and a rehabilitation group, 30 cases in each one (3 cases were dropped out in each group). On the base of the routine western medicine treatment and rehabilitation training, the bowel training and rectal function training were provided, once a day in the rehabilitation group. In the comprehensive therapy group, on the base of the treatment as the rehabilitation group, the tongdu tiaoshen moxibustion was exerted at Yaoyangguan (GV 3), Mingmen (GV 4), Zhiyang (GV 9), Dazhui (GV 14) and Baihui (GV 20), etc, once a day, 30 min each time. In both groups, the treatment for 4 weeks was as one course and 3 courses of treatment were required. Separately, before treatment, after 4, 8 and 12 weeks of treatment, the scores of neurogenic bowel dysfunction (NBD) and World Health Organization quality of life scale (WHOQOL-BREF) were observed and the clinical effect was evaluated after 12 weeks of treatment. After treatment, the total effective rate was 88.9% (24/27) in the comprehensive therapy group, which was higher than 74.1% (20/27) in the rehabilitation group (P<0.05). After 4, 8 and 12 weeks of treatment, NBD scores were all reduced obviously as compared with those before treatment in the two groups (all P<0.01). After 8 and 12 weeks of treatment, NBD scores in the comprehensive therapy group were lower than the rehabilitation group (both P<0.05). After 4, 8 and 12 weeks of treatment, the scores of all of the domains (psychology, physiology, social relations and environment) in WHOQOL-BREF were higher than those before treatment in the two groups (all P<0.01). After 4 weeks of treatment, the scores in the psychology and physiology domains in the comprehensive therapy group were higher than the rehabilitation group (all P<0.05). After 8 and 12 weeks of treatment, the scores of all of the domains in the comprehensive therapy group were higher than the rehabilitation group (all P<0.05). The comprehensive treatment of tongdu tiaoshen moxibustion and rehabilitation training achieves the better effect on intestinal dysfunction of SCI than the simple rehabilitation training and greatly improves the quality of life in SCI patients.

Sliding-cupping along meridian for lymphedema after breast cancer surgery: A randomized controlled trial

ObjectiveTo observe the clinical efficacy difference between sliding-cupping along meridian combined with short-stretch elastic bandage wrapping and comprehensive detumescence therapy in treating lymphedema after breast cancer surgery. MethodsSixty patients with lymphedema after breast cancer surgery were randomly divided into the sliding-cupping group and the comprehensive detumescence therapy (CDT) group, with 30 cases in each one. The sliding-cupping group used the sliding-cupping along meridian therapy, and the sliding-cupping was applied along the three yin meridians and three yang meridians on the hand of the affected-side upper limbs, continuing for 25–30 min. After the sliding-cupping was finished, the affected limb was wrapped with the short-stretch elastic bandage. The CDT group was treated with comprehensive detumescence therapy (CDT). Both groups were treated once a day, with14 times as one course of treatment, and there was totally 1 course of treatment. The changes of circumferences before and after treatment of the affected limb were measured by a flexible ruler, and the efficacy was evaluated. The subcutaneous tissue thickness and the full skin layer thickness of the patients with moderate to severe edema in sliding-cupping group were measured by color Doppler ultrasound. ResultsAfter treatment, the circumferences at the cubital crease, 5 cm above olecranon, and 10 cm above the olecranon of the affected limbs in the sliding-cupping group were (26.02 ± 2.42) cm, (28.43 ± 3.13) cm, and (30.05 ± 2.80) cm respectively, which were all reduced compared with the pre-treatment circumference (27.95 ± 3.00) cm, (30.80 ± 3.38) cm, and (32.17 ± 2.96 cm). In the sliding-cupping group, the post-treatment subcutaneous tissue thicknesses at 5 cm above the olecranon, 10 cm above the olecranon and 5 cm below the olecranon, and full skin layer thickness at 10 cm below the olecranon of the 15 patients with moderate to severe edema were (8.71 ± 2.83) cm, (8.53 ± 2.4) cm, (6.46 ± 1.38) cm, and (1.61 ± 0.17) cm respectively, which were all reduced compared with pre-treatment (11.90 ± 3.56) cm, (11.84 ± 3.27) cm, (9.12 ± 1.84) cm, and (1.87 ± 0.23) cm, and the difference was statistically significant (all P < 0.05). The total effective rate of the sliding-cupping group was 86.6%, and the total effective rate of the CDT group was 80%, and the difference was statistically significant (P < 0.05). ConclusionCompared with CDT, the sliding-cupping along meridian combined with short-stretch elastic bandage wrapping for the treatment of lymphedema after breast cancer surgery was more effective.

Effect of electro-acupuncture combined with psychological intervention on mental symptoms and P50 of auditory evoked potential in patients with internet addiction disorder

OBJECTIVETo observe the therapeutic effects of electro-acupuncture (EA) combined with psychological intervention on the symptom of somzatization or obsession and mental symptom of depression or anxiety and P50 of Auditory Evoked Potential (AEP) on internet addiction disorder (IAD). METHODSOne hundred and twenty cases of IAD were randomly divided into an EA group, a psycho-intervention (PI) group and a comprehensive therapy (EA plus PI) group. Patients in the EA group were treated with EA. Patients in the PI group were treated with cognition and behavior therapy. Patients in the EA plus PI group were treated with electro-acupuncture plus psychological intervention. Scores of IAD, scores of the symptom checklist 90 (SCL-90), latency and amplitude of P50 of AEP were measured before and after treatment. RESULTSThe scores of IAD after treatment significantly decreased in all groups (P < 0.05), and the scores of IAD in the EA plus PI group were significantly lower than those in the other two groups (P < 0.05). The scores of SCL-90 assembled and each factor after treatment in the EA plus PI group significantly decreased (P < 0.05). After treatment in the EA plus PI group, the amplitude distance of S1P50 and S2P50 (S1-S2) significantly increased (P < 0.05). CONCLUSIONEA combined with PI could relieve the mental symptoms of IAD patients, and the mechanism is possibly related to the increase of cerebrum sense perception gating function.

Traditional Chinese Medicine comprehensive therapy for the improvement of motor function in spinal cord injury patients

OBJECTIVETo study the effect of early comprehensive therapy of Traditional Chinese Medicine (TCM) on motor function of in patients with spinal cord injury. METHODSFifty-one standard spinal cord injury patients with paraplegia were randomly assigned to an experimental or control group. The experimental group received TCM comprehensive therapy, and the control group received modern Western Medicine (WM) treatment for 4 weeks. The motor score (MS), Barthel Index (BI) and American Spinal Injury Association (ASIA) grading were measured in both groups before and after treatment. RESULTSAfter treatment, the MS and BI scores of the TCM comprehensive therapy group improved significantly (P < 0.01), and there was no significant difference in ASIA grading (P > 0.05). The differences between the experimental and control groups after treatment were not significant (P > 0.05). CONCLUSIONSEarly TCM comprehensive therapy is an effective method for improving motor function in patients with spinal cord injury.

Effects of comprehensive intensive therapies on the change of intima-media thickness of carotid arteries in type 2 diabetic patients: A report of 4-year follow-up with a literature review.

The aim was to evaluate the effect of comprehensive intensive therapy on the carotid and femoral arteries of intima-media thickness in patients with type 2 diabetes mellitus after 4-year follow-up. In this prospective 4-year study, patients (N = 210) with newly diagnosed type 2 diabetes received either comprehensive intensive therapy (n = 110) or conventional therapy (n = 100). Blood pressure, blood glucose and lipid levels were monitored every 3-6 months, and carotid and femoral arteries of intima-media thickness were monitored with ultrasonography. For the literature review, various databases were searched until 20 December 2014 for studies that evaluated effects of intensive multi-factorial therapies on comprehensive intensive therapy in type 2 diabetes mellitus patients. The comprehensive intensive therapy group had a smaller rate of carotid intima-media thickness increase than the conventional therapy (control) group (p < 0.05). The carotid intima-media thickness in comprehensive intensive therapy group remained stable while the adjusted rate of carotid intima-media thickness increase was 12.55% in the control group. The femoral intima-media thickness change was also smaller in comprehensive intensive therapy group but the difference over time did not reach significance. The carotid intima-media thickness remained stable in type 2 diabetes mellitus patients who received comprehensive intensive therapy, suggesting that multi-factorial intensive therapies might have potential in reducing macro-vascular events in these patients.

Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia.

BackgroundAntipsychotic medication has limited abilities to improve the cognitive impairments that accompany schizophrenia. Adding psychosocial treatment may result in marked improvements in cognitive function, as compared to antipsychotic treatment alone. We hypothesized that a combination of individual and family interventions may be a useful cognitive rehabilitation paradigm for schizophrenia.Materials and methodsAn 18-month follow-up clinical trial of 256 stabilized patients with schizophrenia at six communities in Shanghai, People’s Republic of China were randomly assigned to into either a comprehensive family therapy (CFT) group or a usual daily care (UDC) group. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the Positive and Negative Syndrome Scale (PANSS) were the primary outcome instruments for this study.ResultsThere was no significant difference between the CFT and UDC for all demographic characteristics at the baseline assessment. During the 18-month follow-up observation, changes in RBANS total score indicated that patients undergoing CFT showed greater improvement from baseline to the follow-up assessments in cognitive function than those in the UDC group (F=9.77, P=0.002). Post hoc analysis showed that the CFT group presented with significant differences in the RBANS total score, immediate memory, visuospatial skill, language, attention, and delayed memory sections compared with the UDC after 18 months of follow-up (all P<0.01).ConclusionOur findings suggest that CFT can be easily adapted and may prove to be an effective approach for improving cognitive function in patients with schizophrenia. Our program provides a potential paradigm for cognitive rehabilitation for schizophrenia patients in the community.

Therapeutic effect of oral rehabilitation method combined with Shaker exercise on dysphagia in patients with cerebral infarction

Objective To evaluate the effect of oral rehabilitation method combined with Shaker exercise on the swallowing function and the quality of life in the patients with dysphagia caused by cerebral infarction. Methods A total of 120 patients with swallowing disorder caused by cerebral infarction were randomly divided into conventional treatment group (n=30), oral rehabilitation method group (n=30), Shaker exercise group (n=30) and comprehensive therapy group (n=30). The patients in the conventional treatment group were treated with conventional treatment, while the patients in oral rehabilitation method group received oral rehabilitation method treatment in addition. The Shaker exercise group accepted Shaker exercise and conventional treatment, while the comprehensive therapy group accepted oral rehabilitation method in addition. All patients were assessed with video fluoroscopic swallowing study (VFSS) and swallowing-related quality of life (SWAL-QOL), before treatment and 4-week after treatment. Results Before treatment there was no significant difference among the four groups in VFSS and SWAL-QOL scores (P>0.05). After 4-week treatment the swallowing function showed different degrees of improvement. The difference of VFSS score in the conventional treatment group was not statistically significant before treatment and 4-week after treatment (P=0.38), but it was statistically significant among the other three groups(P<0.01). After 4-week treatment there was significant difference among the four groups in VFSS score (P<0.01), and the comprehensive therapy group curative effect was significantly better than that of the other groups. The total effective rate was 96.67% in the comprehensive therapy group, 26.67% in the conventional treatment group, 66.67% in the oral rehabilitation method group, and 70.00% in the Shaker exercise group. the SWAL-QOL score in the comprehensive therapy group was higher than that of the other three groups. The average SWAL-QOL score was 187.30±10.68 in the comprehensive therapy group, (140.10±16.62) in the conventional treatment group, (161.47±24.53) in the oral rehabilitation method group, and(163.97±23.91) in the Shaker exercise group. Conclusion Application of oral rehabilitation method combined with Shaker exercise in the patients with swallowing disorder caused by cerebral infarction could effectively improve the degree of swallowing disorder and the quality of life. Key words: Dysphagia; Oral rehabilitation method; Shake exercise; Quality of life; Elder

Effect of auricular point sticking therapy on infantile amblyopia

ObjectiveTo compare the differences of effect on infantile amblyopia treated with auricular point sticking therapy and regular comprehensive therapy of western medicine. MethodsTwo hundreds and thirty cases of amblyopia patients were randomly divided into two groups, namely the group of auricular point sticking therapy, which had 120 cases (212 eyes), and the group of comprehensive therapy, which had 110 cases (194 eyes). The seed of Semen Vaccariae was applied at the ear point such as the eye, ear Shenmen, the liver, the spleen and the kidney. Regular comprehensive therapy of western medicine included covering method, vision corrected with glasses and fine exercise. Vision improvements of the two groups were observed with a three-year follow up. ResultsThe effective rates of the auricular point sticking therapy group and comprehensive therapy group of ametropic amblyopia were 81.0% (64/79) and 52.2% (36/69), respectively. The effective rates of anisometropic amblyopia of the two groups were 73.1% (49/67) and 47.7% (31/65), respectively. And the effective rates of the two groups of strabismic amblyopia were 71.2% (47/66) and 45.0% (27/60), respectively. The therapeutic effects of auricular point sticking therapy on all kinds of amblyopia were better than those of the comprehensive therapy (all P<0.05). ConclusionThe effect of auricular point sticking therapy on infantile amblyopia is better than that of regular comprehensive therapy of western medicine, which can obviously improve the vision of the patients with easy manipulations.

Effects of electroacupuncture combined psycho-intervention on cognitive function and event-related potentials P300 and mismatch negativity in patients with internet addiction

To observe the effects of comprehensive therapy (CT) with electroacupuncture (EA) in combination with psycho-intervention (PI) on the cognitive function and event-related potentials (ERP), P300 and mismatch negativity (MMN), in patients with internet addiction (IA) for a preliminary exploration of the possible mechanism of the therapy. One hundred and twenty patients with IA were randomly divided into three groups, and a total of 112 subjects reached the final analysis of the trial, the EA group (39 patients), the PI group (36 patients) and the CT group (37 patients). EA was applied at acupoints Baihui (GV20), Sishencong (EX-HN1), Hegu (LI4), Neiguan (PC6), Taichong (LR3) and Sanyinjiao (SP6), once every other day; PI with the cognitionbehavior mode was implemented every 4 days; both EA and PI were used in the CT group. The treatment course for all patients was 40 days. Changes before and after treatment in terms of scoring by the IA self-rating scale, short-term memory capacity, short-term memory span, and the latency and amplitude of P300 and MMN in patients were observed. After treatment, in all groups, the IA score was lowered significantly (P <0.05) and scores of short-term memory capacity and short-term memory span increased significantly (P <0.05), while the decreased IA score in the CT group was more significant than that in the other two groups (P <0.05). ERP measurements showed that P300 latency was depressed and its amplitude raised in the EA group; MMN amplitude increased in the CT group (all P<0.05). The EA in combination with PI could improve the cognitive function of IA patients, and its mechanism might be related to the speedup of cerebral discrimination on external stimulus and the enhancement of effective resource mobilization during information processing of the brain.

Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma

To study the efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide (TMZ) for gliomas. A total of 78 patients with pathologically confirmed glioma ( from September 2005 to March 2007) were postoperatively divided into 3 groups: a chemotherapy group (n=24), a radiotherapy group (n=25), and a comprehensive therapy group(n=29). The patients received temozolomide alone,3-dimensional conformal radiotherapy alone,3-dimensional conformal radiotherapy combined with temozolomide in the chemotherapy group,the radiotherapy group and the comprehensive therapy group respectively. The survival rate, progression-free survival, overall survival time and adverse reactions were observed. The 3-year survival rate in the comprehensive therapy group was significantly higher than that in the other two groups. The 3-year survival rates were 20.83%, 20.00%, and 41.38% in the chemotherapy group, the radiotherapy group and the comprehensive therapy group respectively. The progression-free survival time was 17.68,17.94, and 23.29 months and the average overall survival time was 20.28, 21.54, and 25.75 months in the chemotherapy group, the radiotherapy group and the comprehensive therapy group, respectively.The adverse reactions were mild and tolerable. Three-dimensional conformal radiotherapy combined with temozolomide is more effective for gliomas than the simple 3-dimensional conformal radiotherapy and the temozolomide chemotherapy alone.

Prediction of calcium level in melamine-related urinary calculi with helical CT: diagnostic performance evaluation and clinical significance

The aim of the study was to investigate the relationship between CT-attenuation and stone calcium level in melamine-related urinary calculi (MRUC). A total of 25 MRUC with known composition and calcium level were included (11 uric acid stones, 2 calcium oxalate stones and 12 mixture stones of uric acid and calcium oxalate). Of all, 18 renal stones accepted alkalization therapy except for 5 lower urinary tract stones and 2 stones of unknown position. With well-matched composition, 61 adult urinary stones were included as controls. Every stone was scanned by helical CT (80 kV/120 kV, 300 mA, pitch 0.625 mm) and the highest CT-attenuation value measured. CT-attenuation values of MRUC increased gradually from uric acid stones, mixture stones to calcium oxalate stones, but were always lower than the values of controls. Furthermore, a strong positive correlation was found between stone CT-attenuation value and stone calcium level (n = 25, r (80kV) = 0.883, p = 0.000; r (120kV) = 0.855, p = 0.000). Compared with alkalization-therapy-alone group, stone CT-attenuation values and stone calcium level in the comprehensive-therapy group were significantly greater (CT(80kV) 1,057 ± 639 vs. 172 ± 61 HU, p = 0.001; CT(120kV) 783 ± 476 vs. 162 ± 60 HU, p = 0.001; Ca 19.83 ± 7.48% vs. 1.30 ± 1.51%, p = 0.000). Fisher's exact test suggested that the stones with higher CT-attenuation values tended to resist alkalization when 400 HU served as the cutoff value (P (80kV) = 0.002, P (120kV) = 0.000). In conclusion, the study was the first to illustrate that the CT-attenuation value could reflect calcium level in MRUC and found that stones with higher CT-attenuation value were not amenable to alkalization because they probably contained greater calcium. For those patients, we believe that comprehensive therapy will be the best choice.

Resultado funcional de infiltración de toxina botulínica multinivel en extremidades inferiores y terapia integral en niños con parálisis cerebral espástica

One of the therapeutic alternatives for the treatment of spasticity in cerebral palsy is the use of botulinum toxin, which, through a temporary denervation, makes it possible to reduce muscle tone, facilitating voluntary mobility. Even though there is abundant literature, mostly with type II evidence, that supports the use of botulinum toxin on the “activity” level of the International Classification of Functioning, Disability and Health, there is scant scientific evidence that demonstrates the influence this therapy has on the “participation” level, which is the purpose of this study. Material and methods A randomized, single blind, controlled clinical trial with controls at 4 weeks, 3 and 6 months. Thirty-six children with hemiplegia or spastic diplegia between 3 – 10 years were randomly assigned with masking into two groups: experimental group with botulinum toxin A plus comprehensive therapy and control group with only comprehensive therapy. The primary endpoints measured were self-care, mobility and instrument transfer of the Wee Functional Independence Measure Instrument. The Gross Motor Function Measure-88 was used to measure the secondary results. Results The weefim score of self-care, mobility and transfers increased 25.0% between baseline and 6 months in the control group and 15.1% in the botulinum toxin group, respectively, there being no statistically significant differences between both groups ( p>0.3). An increase was recorded for the score on the Gross Motor Function Measure-88 in both groups. However, the non-parametric tests indicated that the distribution of the children was similar in both groups during the follow-up, there being no statistically significant differences (Mann Whitney U Test, p>0.10). Conclusion No significant differences were observed in this study regarding functional independence and gross motor function in both groups.