Comprehensive Quality Evaluation System Research Articles

A Methodology of Comprehensive Quality Evaluation for the Underground Space

AbstractUnderground space resources are very important for the purposes of urban sustainable develop Underground space resources are very important for the purposes of urban sustainable development and are an important way in which to realize three‐dimensional urban development. A reasonable and scientific evaluation of underground space resources is the basis for the rational use of land resources and urban planning. On the basis of the geological conditions concerned by predecessors, this study adds the analysis of the two influencing factors of social and economic value, existing facilities and protection needs. The evaluation index is quantified, and the comprehensive quality evaluation system of underground space resources is constructed. Finally, taking Nanshan District of Shenzhen as an example, the evaluation of underground space resources is carried out. The results show that for shallow underground space, the comprehensive quality of underground space resources development in Nanshan District is generally high. Nantou, Nanshan, and Yuehai streets are recommended to actively develop underground space, and Qianhai and Houhai areas are recommended to be cautious in the development and construction of underground space. In addition, this study also provide reference for the purposes of underground space planning in Nanshan District of Shenzhen.

A strategy takes “Yiqing” tablets as an example to carry out simpler multi-component quantification and use fingerprint technology for comprehensive quality consistency evaluation

The comprehensive evaluation of the quality of traditional Chinese medicines (TCM) is an important issue for the continuous progress and exploration of TCM. In this study, a “Yiqing” tablet (YQT) was taken as an example, and the sample quality was comprehensively investigated by multi-component quantification, multi-dimensional fingerprint construction, and antioxidant activity analysis. Based on high performance liquid chromatography (HPLC) and fourier transform infrared spectroscopy (FTIR) fingerprint, accurate and fast multi-component quantification is achieved by reliable Multi-markers assay by mono-linear method (MAML) method and verified partial least squares regression (PLSR) model. The basic HPLC fingerprint and the special FTIR quantitative fingerprint were evaluated by SQFM, and the rich fingerprint qualitative and quantitative information of the sample was obtained. The characteristic parameter (blocking rate (BR)) characterizing antioxidant activity in the electrochemical (EC) fingerprint was excavated for the first time, and the fingerprint-efficacy analysis results with HPLC and FTIR were obtained through bivariate correlation analysis (BCA). The results showed that 25 components in the HPLC fingerprint and had antioxidant activity, and most bands of FTIR showed antioxidant activity. Finally, by combining the evaluation results of HPLC and FTIR fingerprint using the mean method, all samples were classified as first level, except for S1, demonstrating the consistency of sample quality. Based on the comprehensive quality evaluation system combining vertical and horizontal combination, this study provides a new idea for achieving comprehensive quality evaluation of TCM.

Hydrochemical characteristics and water quality assessment of natural water in the South China Mountains: the case in Lianzhou.

South China Mountain Region has a well-developed water system with the most abundant water in China. Untreated natural water is the main source of drinking water for the local people. This study aimed to investigate the hydrochemical characteristics and trace element concentrations of natural water in the mountainous regions of South China. In this study, 116 water samples were collected. Traditional hydrochemical methods, water quality index (WQI), hazard index (HI), and nutrient speciation of trace elements (NSTE) were used for analysis. In general, the hydrochemical type was mainly Ca-HCO3- type. The hydrochemical characteristics were mainly influenced by the weathering of calcite and silicate rocks. Overall total dissolved solids (TDS) were low, indicating mainly soft and very soft water. The water that met the standards for mineral water had an average concentration of 59.69mg/L for Sr (strontium) and an average concentration of 0.46mg/L for H2SiO3 (silicic acid). Although the water quality index (WQI) indicated that 91.3% of the water samples in the study area were of good quality (WQI < 25), 2.58% of the water samples had significant non-carcinogenic risk (HI > 1) due to the high As and Pb concentrations. The water in the study area contributed significantly to human intake of Sr, Cr, and V, accounting for 8.4, 8.3, and 7.7% of the required daily intake for adults, respectively. It is recommended that a comprehensive water quality evaluation system be constructed to ensure that mountain water is managed for development and safe to drink.

Pharmaceutical process-omics for quality control of traditional Chinese medicine preparations: A 1H-qNMR assisted case study of Guanxinning injection

Guanxinning injection (GXNI) is a traditional Chinese medicine preparation derived from Salviae Miltiorrhizae Radix et Rhizoma and Chuanxiong Rhizoma. It is produced through a series of processes involving water extraction, ethanol precipitation, and other techniques. GXNI is primarily used for treating angina pectoris in coronary heart disease, and it has shown remarkable efficacy in clinical practice. One of the key components responsible for its pharmacological effects is salvianolic acids. However, these components are known for their poor stability and susceptibility to pH and temperature variations. Therefore, it is crucial to focus on ensuring the quality and stability of salvianolic acids in GXNI. In this study, we employed Proton nuclear magnetic resonance (1H NMR) to analyze the intermediate products formed during the manufacturing of GXNI. We thoroughly examined the spectra of these intermediates and developed a precise 1H-qNMR method for the accurate quantification of various classes of chemical components present in GXNI. Additionally, we applied this method to investigate how the composition of GXNI evolves and transfers throughout the entire production process. To further enhance our understanding, we employed Principal Component Analysis (PCA) and Orthogonal Partial Least Squares Discriminant Analysis (OPLS-DA) to identify critical steps in the production process and to identify potential quality markers (Q-markers) associated with these processes. Our study sheds light on the dynamic changes in composition that occur during the production of GXNI. This research serves as a foundation for establishing a comprehensive quality evaluation system for GXNI, ensuring its efficacy and safety in clinical applications.

Geoherbalism Metabolomic Analysis of Atractylodes lancea (Thunb.) DC. by LC-Triple TOF-MS/MS and GC-MS.

The rhizome of Atractylodes lancea (Thunb.) DC. (AL), called Maocangzhu in Chinese, is a geoherbalism medical herb in Jiangsu Province that is often used in the prescription of traditional Chinese medicine (TCM), such as for the treatment of COVID-19. The landform and climatic environment of each province varies greatly from south to north, which has an important influence on the chemical constituents in AL. However, there is a lack of research on the significance of its geoherbalism, especially in water-soluble parts other than volatile oil. In this study, eight known compounds were isolated and obtained as reference substances from AL. In addition, liquid chromatography coupled with triple-quadrupole time-of-flight tandem mass spectrometry (LC-triple TOF-MS/MS) and gas chromatography-mass spectrometry (GC-MS) were used to analyze and characterize chemical constituents from different habitats. Moreover, orthogonal partial least-squares discriminant analysis (OPLS-DA) was applied to reveal the differential metabolomics in AL from different habitats based on the qualitative information of the chemical constituents. Results showed that a total of 33 constituents from GC-MS and 106 constituents from LC-triple TOF-MS/MS were identified or inferred, including terpenoids, polyacetylenes, and others; meanwhile, the fragmentation pathways of different types of compounds were preliminarily deduced from the fragmentation behavior of the major constituents. According to the variable importance in projection (VIP) and p-values, only one volatile differential metabolite was identified by GC-MS screening: β-eudesmol. Overall, five differential metabolites were identified by LC-triple TOF-MS/MS screening: sucrose, 4(15),11-eudesmadiene; atractylenolide I, 3,5,11-tridecatriene-7,9-diyne-1,2-diacetate, and (3Z,5E,11E)-tridecatriene-7,9-diynyl-1-O-(E)-ferulate. This study provides metabolomic information for the establishment of a comprehensive quality evaluation system for AL.

Development of a Comprehensive Quality Evaluation System for Foxtail Millet from Different Ecological Regions.

Foxtail millet (Setaria italica L.) is a critical grain with high nutritional value and the potential for increased production in arid and semiarid regions. The foxtail millet value chain can be upgraded only by ensuring its comprehensive quality. Thus, samples were collected from different production areas in Shanxi province, China, and compared in terms of quality traits. We established a quality evaluation system utilizing multivariate statistical analysis. The results showed that the appearance, nutritional content, and culinary value of foxtail millet produced in different ecological regions varied substantially. Different values of amino acids (DVAACs), alkali digestion values (ADVs), and total flavone content (TFC) had the highest coefficients of variation (CVs) of 50.30%, 39.75%, and 35.39%, respectively. Based on this, a comprehensive quality evaluation system for foxtail millet was established, and the quality of foxtail millet produced in the five production areas was ranked in order from highest to lowest: Dingxiang > Zezhou > Qinxian > Xingxian > Yuci. In conclusion, the ecological conditions of Xinding Basin are favorable for ensuring the comprehensive quality of foxtail millet. .

A Comprehensive Quality Evaluation System for University Students Based on Teacher Performance Coefficients

A Comprehensive Quality Evaluation System for University Students Based on Teacher Performance Coefficients

Qualitative Analysis and Componential Differences of Chemical Constituents in Lysimachiae Herba from Different Habitats (Sichuan Basin) by UFLC-Triple TOF-MS/MS.

Lysimachiae Herba (LH), called Jinqiancao in Chinese, is an authentic medical herb in Sichuan Province often used in the prescription of traditional Chinese medicine (TCM). However, in recent years, there has been a lack of comprehensive research on its chemical components. In addition, the landform of Sichuan Province varies greatly from east to west and the terrain is complex and diverse, which has an important influence on the chemical constituents in LH. In this study, ultrafast liquid chromatography coupled with triple-quadrupole time-of-flight tandem mass spectrometry (UFLC-triple TOF-MS/MS) was used to analyze the samples of LH from eight different habitats in Sichuan Basin. The constituents were identified according to the precise molecular weight, the fragment ions of each chromatographic peak and the retention time of the compound obtained by high-resolution mass spectrometry, combined with software database searches, standard comparisons and the related literature. Differential chemical constituents were screened using partial least squares discriminant analysis (PLS-DA) and t-tests. The results showed that a total of 46 constituents were identified and inferred, including flavonoids, phenolic acids, amino acids, tannins, fatty acids and coumarins; the fragmentation pathways of the main constituents were preliminarily deduced. According to the variable importance in projection (VIP) and p-values, four common differential constituents were screened out, 2-O-galloylgalactaric acid, quercetin 3-O-xylosyl-rutinoside, nicotiflorin and kaempferol 3-rutinosyl 7-O-alpha-l-rhamnoside. This study provides basic information for the establishment of a comprehensive quality evaluation system for LH.

Microbial activity and community structure in PM2 .5 at different heights in ground boundary layer of Beijing atmosphere under various air quality levels.

The outbreak of the COVID-19 epidemic is a reminder that aerosols have important health effects as a potential route for disease transmission. Biological components in aerosols (especially PM2.5 ) may pose potential threats to humans as pathogens and allergens. Research on PM2.5 and biological components currently focuses mainly on polluted conditions, with less emphasis on clean environments. Sampling has also been primarily based on a single point with a lack of data at different positions. In this study, a modified fluorescein diacetate hydrolysis method was used to measure microbial activity in PM2.5 at different altitudes over a year in Beijing, China. A high-throughput sequencing method was used to study the microbial community. Results showed that microbial activity 1.5m (0.0465 ng m-3 ) above the ground was higher than 31.5m (0.0348 ng m-3 ). There was higher microbial activity at both heights during spring. Furthermore, a positive correlation was observed between microbial activity and relative abundance of dominant species. Microbial activity increased during autumn and winter increased alongside the pollution level, but in spring higher levels of microbial activity were observed in excellent or good weather conditions. The results from this study are valuable for further research regarding the biological components of atmospheric PM, the prevention of biological pollution, and establishing a comprehensive air quality evaluation system.

Genotypic diversity of quality traits in Chinese foxtail millet (Setaria italica L.) and the establishment of a quality evaluation system

Foxtail millet (Setaria italica L.) is an important reserve cereal crop, and its nutritional and medicinal properties have seen its demand increase in recent years. Therefore, it is important to establish an evaluation system for the comprehensive assessment of its quality. We assessed 90 accessions of foxtail millet from China for 23 quality traits. The results showed that the 23 quality traits had diverse coefficients of variation, with the greatest variation in a*, phosphorus content, and potassium contents, at 37.71, 28.81, and 20.18%, respectively. Cluster analysis defined five categories that were consistent with the geographical origins of the accessions. Seven principal components were also extracted from the 23 traits using principal component analysis. A comprehensive quality evaluation system was established, and 8 high-quality accessions were identified. The findings of the present study could facilitate the breeding of high-quality foxtail millet and enhance quality evaluation activities.

Impact of promoting employment quality on new generation migrant workers’ settlement intention a study based on gender perspective

This meta-analysis summarizes the research findings of many local and international experts and constructs a comprehensive employment quality evaluation system based on factors including monthly salary, working hours, job stability, career reputation, social security, labor rights, development prospective, worker satisfaction and more. Binary Logistic Regression was used to analyze and discuss new generation migrant workers’ settlement intention, both as a whole and for different genders. Analysis suggests there are significant gender differences when it comes to settlement intention. Education level, social circle, skill development, weekly working hours and colleague relationship all have profound impact on new generation female migrant workers’ settlement intention. On the other hand, only career type and overall job satisfaction show significant influence over male migrant workers’ decision. It has to be noted that overall job satisfaction is an integrative indicator. Therefore, this paper suggests that in order to study the relationship between employment and settlement intention, one should start from analyzing comprehensive employment quality indicators with special attention paid to gender differences.

Screening of active fractions from Curcuma Longa Radix isolated by HPLC and GC-MS for promotion of blood circulation and relief of pain

Ethnopharmacological relevanceCurcuma Longa Radix (Huangsiyujin in Chinese, HSYJ) has been used in clinical for thousands of years as a traditional Chinese medicine (TCM) and has the effects of invigorating the blood circulation, relieving pain, promoting qi circulation and relieving depression, besides, it is able to clear heart heat and cool blood and cure jaundice. The study aims to determine the active fractions of HSYJ for promotion of blood circulation and relief of pain, and to identify their chemical constituents. Material and methodsHSYJ was extracted by the systematic solvent method. The effects of promoting blood circulation and relieving pain were determined by measuring pain threshold (hot-plate test), latency of twisting and writhing times (acetic acid induced writhing test), and hemorheology of mice. Chemical constituents of the extractive fractions were analyzed by Gas Chromatography-Mass Spectrometer (GC-MS) or High Performance Liquid Chromatography (HPLC). ResultsThe results showed that five fractions (volatile oil fraction, petroleum ether fraction, ethyl acetate fraction, 1-butanol fraction and water fraction) all could increase pain threshold, prolong latency of twisting, decrease the writhing times and influence hemorheology. However, the effects of the volatile oil fraction and ethyl acetate fraction were better than other fractions. Three constituents, namely bisdesmethoxycurum, desmethoxycurumin and curcumin were identified from the active fractions by comparing with standard preparation through HPLC analysis. Forty-five compounds including aR-Turmerone, Curlone, Tumerone, Cyclohexene,1-methyl-4-(1-methylethylidene)-, trans-Sesquisabinene hydrate, (E)-Atlantone, α-curcumene and Zingiberene were identified from the volatile oil fraction by GC-MS. ConclusionHSYJ possessed the effect of promoting blood circulation and relieving pain. Curcumins and their derivatives were the major constituents and might be the main bioactive ingredients for the promotion of blood circulation and relief of pain. The study provided evidence and formed a basis for the establishment of HSYJ comprehensive quality evaluation system related to traditional efficacy. It is beneficial to the quality control of HSYJ and its proprietary Chinese medicine.

Monitoring quality consistency of Liuwei Dihuang Pill by integrating the ultraviolet spectroscopic fingerprint, a multi-wavelength fusion fingerprint method, and antioxidant activities.

Liuwei Dihuang Pill, a classical traditional Chinese medicine, has been widely used to treat kidney yin deficiency in China for hundreds of years. Little attention, however, has been paid to quality control methods for this formulation. In the present study, we aimed to establish a comprehensive and practical quality evaluation system for Liuwei Dihuang Pill. Thus, ultraviolet spectroscopic fingerprints and multi-wavelength fusion fingerprints have been proposed for quality consistency evaluation of the popular patent. The similarity analysis of Liuwei Dihuang Pill samples was evaluated by systematic quantitative fingerprint method from qualitative and quantitative perspectives. The results showed that 26 batches of samples were classified into five grades for fusion fingerprints and three grades for ultraviolet spectroscopic fingerprints. Moreover, the fingerprint-efficacy correlation was also established and confirmed through the partial least squares model to visualize the antioxidant activity of Liuwei Dihuang Pill in vitro. In conclusion, these results indicated that integrating ultraviolet spectroscopic fingerprints and multi-wavelength fusion fingerprints coupled with antioxidant activities provide a rapid and effective approach to monitor the quality consistency of Liuwei Dihuang Pill.

A Comprehensive Quality Evaluation System for Complex Herbal Medicine Using PacBio Sequencing, PCR-Denaturing Gradient Gel Electrophoresis, and Several Chemical Approaches.

Herbal medicine is a major component of complementary and alternative medicine, contributing significantly to the health of many people and communities. Quality control of herbal medicine is crucial to ensure that it is safe and sound for use. Here, we investigated a comprehensive quality evaluation system for a classic herbal medicine, Danggui Buxue Formula, by applying genetic-based and analytical chemistry approaches to authenticate and evaluate the quality of its samples. For authenticity, we successfully applied two novel technologies, third-generation sequencing and PCR-DGGE (denaturing gradient gel electrophoresis), to analyze the ingredient composition of the tested samples. For quality evaluation, we used high performance liquid chromatography assays to determine the content of chemical markers to help estimate the dosage relationship between its two raw materials, plant roots of Huangqi and Danggui. A series of surveys were then conducted against several exogenous contaminations, aiming to further access the efficacy and safety of the samples. In conclusion, the quality evaluation system demonstrated here can potentially address the authenticity, quality, and safety of herbal medicines, thus providing novel insight for enhancing their overall quality control.Highlight: We established a comprehensive quality evaluation system for herbal medicine, by combining two genetic-based approaches third-generation sequencing and DGGE (denaturing gradient gel electrophoresis) with analytical chemistry approaches to achieve the authentication and quality connotation of the samples.

Comprehensive Quality Evaluation System for Manufacturing Enterprises of Large Piston Compressors

Piston compressors are necessary dynamic equipment in chemical engineering and petrochemical industry. Establishment of a quality evaluation system for Chinese manufacturing enterprises of large piston compressors is important for the proper evaluation of production quality. The evaluation system can serve both government decision-making and user selection-making. Furthermore, the quality evaluation system is beneficial for identifying production bottleneck and improving production quality. A hierarchical analytic process is adopted in this paper to establish a comprehensive quality evaluation system. The system characteristics can be summarized into three levels, two main lines, and one correction. The first level consists of two main routes, external effects and intrinsic effects. The second level includes 6 external factors and 7 intrinsic factors. The third level is composed of 81 elements. In addition, the product accident history is introduced at the first level as a correction item. The evaluation system was implemented using B/S architecture and the standard SSM framework with MVC design pattern.

Quality evaluation of Shenmaidihuang Pills based on the chromatographic fingerprints and simultaneous determination of seven bioactive constituents.

In this study, we aimed to establish a comprehensive and practical quality evaluation system for Shenmaidihuang pills. A simple and reliable high-performance liquid chromatography coupled with photodiode array detection method was developed both for fingerprint analysis and quantitative determination. In fingerprint analysis, relative retention time and relative peak area were used to identify the common peaks in 18 samples for investigation. Twenty one peaks were selected as the common peaks to evaluate the similarities of 18 Shenmaidihuang pills samples with different manufacture dates. Furthermore, similarity analysis was applied to evaluate the similarity of samples. Hierarchical cluster analysis and principal component analysis were also performed to evaluate the variation of Shenmaidihuang pills. In quantitative analysis, linear regressions, injection precisions, recovery, repeatability and sample stability were all tested and good results were obtained to simultaneously determine the seven identified compounds, namely, 5-hydroxymethylfurfural, morroniside, loganin, paeonol, paeoniflorin, psoralen, isopsoralen in Shenmaidihuang pills. The contents of some analytes in different batches of samples indicated significant difference, especially for 5-hydroxymethylfurfural. So, it was concluded that the chromatographic fingerprint method obtained by high-performance liquid chromatography coupled with photodiode array detection associated with multiple compounds determination is a powerful and meaningful tool to comprehensively conduct the quality control of Shenmaidihuang pills.

Construction of Comprehensive Quality Evaluation and Grading System for Fresh Fuji Apple in Luochuan, Shaanxi

Construction of Comprehensive Quality Evaluation and Grading System for Fresh Fuji Apple in Luochuan, Shaanxi

Study on Comprehensive Quality Evaluation System and Method of College Students

Developing high-quality talents, who are needs by nation and society, is the fundamental task for institutions. And people more and more concern college students’ quality. This paper firstly introduces the related contents about college students’ comprehensive quality evaluation, and builds the evaluation index system, using the analytic hierarchy process to determine the weight of each index.

The Application of Modified Delphi-AHP Method in the College Students’ Comprehensive Quality Evaluation System

The Application of Modified Delphi-AHP Method in the College Students’ Comprehensive Quality Evaluation System

Construction the Quality Standard and Evaluation Mechanism of College Student's Social Practice

Abstract After investigation and research, we set up a scientific, comprehensive, reasonable Curricular and social practice quality standard and evaluation system which can adapt to our practical teaching well. It would ensure social practice teaching effect, improve their innovative ability.