Complex Spectral Optical Coherence Tomography Research Articles

Sine-modulated wavelength-independent full-range complex spectral optical coherence tomography with an ultra-broadband light source

We present a full-range complex spectral domain optical coherence tomography with an ultra-broadband light source based on sinusoidal modulation. For the sinusoidal modulation strategy, a lead zirconate titanate stack actuator is employed to achieve the sinusoidal vibration of a mirror and therefore to get a series of spectral interferogram with different phase delays. The purpose of this strategy is to get higher performance complex-conjugate artifact elimination. Bessel separation of the signal sequence at each wavelength of the spectrometer was used to reconstruct the real and imaginary components of interference fringes; however, the sinusoidal modulation method is independent of light source wavelength. The experimental results demonstrated that the method had an excellent performance in a complex-conjugate suppression of 50 dB for a full width at half maximum bandwidth of 236 nm, and it has better anti-artifact ability and more flexible range in phase shifting than the conventional wavelength-dependent phase-shifting method on a full-range complex spectral optical coherence tomography system. Furthermore, the effect of the hysteresis error of lead zirconate titanate actuators on the performance of complex-conjugate artifact elimination was investigated and the solution of lead zirconate titanate positioning performance for both conventional phase-shifting and sine-modulation methods was suggested.

Complex spectral OCT in human eye imaging in vivo

Complex spectral optical coherence tomography in comparison to spectral optical coherence tomography produces images free of parasitic terms with extended measurement range. This technique requires stability of the object during at least three consecutive measurements. In this paper we present how to improve this technique to make measurements less sensitive to involuntary eye movements. The first images of human skin and anterior chamber of the eye in vivo based on complex spectral optical coherence tomography are presented.

Full range complex spectral optical coherence tomography technique in eye imaging

We demonstrate a new implementation of complex spectral optical coherence tomography (OCT) in biomedical imaging. By reconstruction of both amplitude and phase we are able to use the negative and positive optical path differences to get images of objects of considerable thickness. An accompanying reduction of coherent noise improves the quality of the images. The property of the complex spectral OCT that permits the measurement range to be increased and permits the simultaneous use of phase and amplitude in spectral systems was not described previously. To show the potential of this technique we measured an anterior chamber of a porcine eye in vitro.