Complex Multilayer Structures Research Articles

A Two-Step Dry Etching Model for Non-Uniform Etching Profile in Gate-All-Around Field-Effect Transistor Manufacturing.

The Gate-All-Around Field-Effect Transistor (GAAFET) is proposed as a successor to Fin Field-Effect Transistor (FinFET) technology to increase channel length and improve the device performance. The GAAFET features a complex multilayer structure, which complicates the manufacturing process. One of the most critical steps in GAAFET fabrication is the selective lateral etching of the SiGe layers, essential for forming the inner-spacer. Industry commonly encounters a non-uniform etching profile during this step. In this paper, a continuous two-step dry etching model is proposed to investigate the mechanism behind the formation of the non-uniform profiles. The model consists of four modules: anisotropic etching simulation, Ge atom diffusion simulation, Si/SiGe etch selectivity calculation and SiGe selective etching simulation. By calibrating and verifying this model with experimental data, the edge rounding and gradient etching rates along the sidewall surface are successfully simulated. Based on further examination of the influence of chamber pressure on the profile using this model, the inner-spacer shape is improved experimentally by appropriately reducing the chamber pressure. This work aims to provide valuable insights for etching process recipes in advanced GAAFETs manufacturing.

Research on the impact mechanism and parameter optimization of RTP structure layer fusion process

Fiber-reinforced thermoplastic composite pipes (RTP) possess a complex multilayer structure. Apart from the melting process of the reinforced layer, the melting process between the inner and outer layers and the reinforced layer is equally crucial. Factors such as heating time, heating temperature, and pipe diameter significantly influence the degree of tight bonding between these layers. The purpose of this study is to investigate the influence mechanism of the fusion process between the three main layers of RTP and to perform parameter optimization analysis. First, Box-Behnken response surface method and finite element analysis were used to obtain the softened layer thickness under different parameters and to couple the influence mechanism of process parameters on the softened layer thickness. Then, single parameter sensitivity analysis was used to reveal the influence mechanism of each parameter change on the softened layer thickness of the pipe, and then the coupling analysis of the process parameters was carried out. The analysis results show that the softened layer thickness is most sensitive to the change of heating temperature, followed by heating time and pipe diameter. Finally, the optimal parameter combination was obtained through the expected function method, and experiments were conducted on finished pipes.

Diamine-surfactant adsorption at the air–water interface: The impact of the diamine structure, surfactant structure and solution pH

The biogenic amines, polyamines, such as putrescine and cadavarine, are small flexible polycations. They interact with charged biological species and have a range of important biological functions. Their strong interaction with anionic surfactants results in enhanced adsorption at interfaces. Aspects of the impact of the polyamine molecular weight and structure on the pattern of surfactant adsorption at the air–water interface have been explored previously using neutron reflectivity, NR, and surface tension, ST. However there is limited evidence for the extent to which surfactant adsorption can be manipulated and the impact of the diamine structure and surfactant headgroup structure on surfactant adsorption at the air–water interface is reported here.The addition of putrescine [1,4 diaminobutane or butanediamine] over the pH range 3 to 10 enhances significantly the adsorption of sodium dodecyl sulfate, SDS, sodium dodecyl diethylene sulfate, SLES, and sodium tetradecyl methyl ester sulfonate, MES. For SDS and to a lesser extent MES there are regions where surface multilayer adsorption occurs at both pH 3 and 10, and this extends significantly the range of polyamine structures for which this is observed. Modifying the diamine spacer with ethylene oxide groups of varying length still results in enhanced adsorption for SDS and MES, but the enhancement is less pronounced and depends upon the size of the ethylene oxide group. However the incorporation of the ethylene oxide group does suppresses the formation of the more complex surface multilayered structures.

Analysis of micro-defect-induced cracking in the IPyC layer of TRISO particle with the XFEM

PurposeWe use the extended finite element method (XFEM) to model the whole process of initiation and propagation of cracks in the inner dense pyrolytic carbon (IPyC) layer of tri-structural isotropic (TRISO) particle induced by the microdefect in an irradiation-induced thermomechanical coupling environment and study the effect of microdefect sizes on the propagation path.Design/methodology/approachThe irradiation-induced thermal–mechanical coupling analysis is first conducted for the representative volume element (RVE) of the TRISO particle by using the conventional finite element method (CFEM) so that the stress distribution is obtained. The stress results are then restored for the enriched elements, and the simulation of crack initiation and propagation is eventually carried out by using the XFEM.Findings1. As a crack initiates in the IPyC layer, it will terminate at the free edge of the RVE TRISO particle in the end. 2. The size of the microdefect has a significant impact on the propagation path.Originality/valueThe ceramic dispersion microencapsulated (CDM) fuel is a good accident-resistant fuel whose safe operation is crucial to the safety and reliability of the whole nuclear reactor. It is of great scientific significance and practical value to study the irradiation-induced thermomechanical coupling stress distribution and cracking behavior in the IPyC layer of TRISO particles for the CDM fuel. Crack initiation and propagation analysis is challengeable for this complex multi-layer structure. This can help understand the failure mechanism of TRISO particles and evaluate the operation safety of the reactor.

Considerations for extracting moiré-level strain from dark field intensities in transmission electron microscopy

Bragg interferometry (BI) is an imaging technique based on four-dimensional scanning transmission electron microscopy (4D-STEM) wherein the intensities of select overlapping Bragg disks are fit or more qualitatively analyzed in the context of simple trigonometric equations to determine local stacking order. In 4D-STEM based approaches, the collection of full diffraction patterns at each real-space position of the scanning probe allows the use of precise virtual apertures much smaller and more variable in shape than those used in conventional dark field imaging such that even buried interfaces marginally twisted from other layers can be targeted. With a coarse-grained form of dark field ptychography, BI uses simple physically derived fitting functions to extract the average structure within the illumination region and is, therefore, viable over large fields of view. BI has shown a particular advantage for selectively investigating the interlayer stacking and associated moiré reconstruction of bilayer interfaces within complex multi-layered structures. This has enabled investigation of reconstruction and substrate effects in bilayers through encapsulating hexagonal boron nitride and of select bilayer interfaces within trilayer stacks. However, the technique can be improved to provide a greater spatial resolution and probe a wider range of twisted structures, for which current limitations on acquisition parameters can lead to large illumination regions and the computationally involved post-processing can fail. Here, we analyze these limitations and the computational processing in greater depth, presenting a few methods for improvement over previous works, discussing potential areas for further expansion, and illustrating the current capabilities of this approach for extracting moiré-scale strain.

N-level complex helical structure modeling method

This paper primarily explores the modeling method of n-level complex helical structures with coal mining machine cables as the research object. The paper first elaborately introduces the modeling method of n-level helix curves based on parametric equations and coordinate transformations, and compensates for the n-level helix curves with corrected pitch, which can obtain more accurate n-level helix curves and improve the accuracy of n-level helix curves modeling. Subsequently, based on this high-precision n-level helix curves modeling method, the paper elaborates on the method of solving pitch and twisting radius of multi-layer helical structure. Calculation scripts were written based on the above methods, which can be used to batch calculate the twisting radius and pitch of each layer structure in multi-layer structures when satisfying the conditions of in-layer tangency, inter-layer tangency, and extrusion deformation, and retain the actual results through logical judgment. Then, based on the above two methods, the paper developed a modeling method for braided structures based on piecewise functions containing fifth-order polynomials, which can effectively avoid the problem of insufficiently dense arrangement of braided lines and easy interference in traditional methods. Finally, a set of modeling tools was developed using C# and Python in Grasshopper to implement the modeling algorithm. Taking the MCPT-1.9/3.3 3120 + 170 + 4 * 10 coal mining machine cable as an example. The cable was modeled using both the method proposed in this paper and the traditional method. Comparative data shows that the method proposed in this paper can reduce errors by 3.31E6 times in the second-level and above helical structures. In addition this paper compares the standard line length, measured line length, and the line length established by the proposed model, showing that the relative errors are both less than 0.1941%. This paper provides a new, systematic, high-precision, and full-process cable modeling method, in which all parameters except the process parameters are accurately solved by equations. It lays a theoretical foundation for the high-precision simulation and intelligent sensing cables, which is of great significance for improving the safety, stability, and efficient development of the coal mining industry. The research results of the paper can not only be applied to the modeling of coal mining machine cables but also can be extended to the modeling of other complex multi-layer helical structures.

Numerical modeling of fiber orientation in multi-layer, isothermal material-extrusion big area additive manufacturing

Fiber orientation is a critical factor in determining the mechanical, electrical, and thermal properties of 3D-printed short-fiber polymer composites. However, the current numerical studies on predicting fiber orientation are limited to straight single-strand configurations, while the actual printed parts are often composed of complex multi-layer structures. To address this issue, we conducted numerical simulations of material extrusion in multi-layer big-area additive manufacturing without any post-deposition strand morphology modification mechanism. By examining the effects of material properties and printing conditions when extruding and depositing strands on a fixed substrate as well as previously deposited layers, it was possible to observe the complex interplay between multiple layers and its impact on fiber orientation. The work and methodology presented in this paper can be used to identify optimal extrusion-to-nozzle speed ratios, material rheology, fiber content, and fiber aspect ratio to achieve the desired performance and thermo/mechanical properties of additively manufactured parts. This work is an important contribution towards the manufacture of high-performance, short-fiber polymer composites as the presented methodology can enable engineers to precisely predict and tailor the fiber orientation in 3D printed parts.

Effects of surface and subsurface water/ice on spatial distributions of impact crater ejecta on Mars

Ejecta blankets around craters on a km-scale show stark differences in the ejecta mobility (maximal extent of ejecta divided by the crater radius) with latitude and types of plains on Mars, which has been known for a long time (Barlow and Pollak, 2002; Li et al., 2015) but is not well-understood. Our main goal is to explore the idea that the subsurface rheology drives ejecta dynamics and leaves characteristic, observable imprints in the spatial distributions of ejecta. We conduct numerical simulations of impact cratering into a variety of subsurface models and study the impact of varied subsurface material (porous basalt, water ice, water), as well as structure and layering on impact sites and properties of impact ejecta. Our models consider variations in the depth of water or ice covering basalt; the thickness of buried ice; and the depth of burial of ice. We find that ejection angles and velocities depend on these quantities and configurations, e.g. velocities decrease and angles of ejection increase with increasing water layer thickness, buried ice thickness, or thickness of basaltic debris over an ice sheet. As a result, several ejecta characteristics derived from ejecta thickness profiles carry information about the underlying rheology. Specifically, the ejecta mobility, as well as the radial position of the maximum and the slope of the ejecta thickness profiles are diagnostic. The power-law function of the thickness profile of the ejecta blanket right after formation is a good indicator of ejecta from water- or ice-covered targets but not from more complex multi-layered structures, hence we caution against using scaling relations to describe ejecta from such targets. As any surface water/ice volatile mass is unstable on Mars, we also consider the geomorphology of craters and ejecta after the loss of volatiles. Our main findings include the observation that after the loss of surface volatiles, craters which formed in water-covered targets would appear shallower than those formed in basalt. The ejecta mobilities observed today would also be smaller if craters formed in volatile-covered targets than in basalt. Our findings can aid the interpretation of data returned from cameras onboard multiple spacecraft orbiting Mars such as HiRISE, CaSSIS, or CTX, and constitute a proof of concept of the hypothesis that information on the subsurface, including where ice is or was present, is encoded in the ejecta profile and spatial distribution.

Wide-incident-angle, polarization-independent broadband-absorption metastructure without external resistive elements by using a trapezoidal structure

The absorption of electromagnetic waves in a broadband frequency range with polarization insensitivity and incidence-angle independence is greatly needed in modern technology applications. Many structures based on metamaterials have been suggested for addressing these requirements; these structures were complex multilayer structures or used special materials or external electric components, such as resistive ones. In this paper, we present a metasurface structure that was fabricated simply by employing the standard printed-circuit-board technique but provides a high absorption above 90% in a broadband frequency range from 12.35 to 14.65 GHz. The metasurface consisted of structural unit cells of 4 symmetric substructures assembled with a metallic bar pattern, which induced broadband absorption by using a planar resistive interaction in the pattern without a real resistive component. The analysis, simulation, and measurement results showed that the metasurface was also polarization insensitive and still maintained an absorption above 90% at incident angles up to 45°. The suggested metasurface plays a role in the fundamental design and can also be used to design absorbers at different frequency ranges. Furthermore, further enhancement of the absorption performance is achieved by improved design and fabrication.

AI-driven design of customized 3D-printed multi-layer capsules with controlled drug release profiles for personalized medicine

Personalized medicine aims to effectively and efficiently provide customized drugs that cater to diverse populations, which is a significant yet challenging task. Recently, the integration of artificial intelligence (AI) and three-dimensional (3D) printing technology has transformed the medical field, and was expected to facilitate the efficient design and development of customized drugs through the synergy of their respective advantages. In this study, we present an innovative method that combines AI and 3D printing technology to design and fabricate customized capsules. Initially, we discretized and encoded the geometry of the capsule, simulated the dissolution process of the capsule with classical drug dissolution model, and verified it by experiments. Subsequently, we employed a genetic algorithm to explore the capsule geometric structure space and generate a complex multi-layer structure that satisfies the target drug release profiles, including stepwise release and zero-order release. Finally, Two model drugs, isoniazid and acetaminophen, were selected and fused deposition modeling (FDM) 3D printing technology was utilized to precisely print the AI-designed capsule. The reliability of the method was verified by comparing the in vitro release curve of the printed capsules with the target curve, and the f2 value was more than 50. Notably, accurate and autonomous design of the drug release curve was achieved mainly by changing the geometry of the capsule. This approach is expected to be applied to different drug needs and facilitate the development of customized oral dosage forms.

Optimizing the management, control, and computation of skin depth in laminated structures considering reflection effects

This study introduces an alternative method for calculating multilayered skin depth in laminated structures. It concentrates on locating the layer where the skin effect occurs and developing a novel formula for skin depth. This method involves attenuating the electric field as it traverses the layers of the structure until it reaches the 1/e point. The equation's resolution considers the reflection that occurs when electromagnetic wave transitions between layers. To execute computations with precision and efficiency, a numerical algorithm is implemented. An in-depth examination will be conducted to identify materials in the first, second, and third positions within the multilayer structure, where the skin effect may manifest in specific frequency ranges, including those defined by the IEEE. The approach provides a reliable mean to precisely control the skin effect's location in complex multilayered structures and select materials to minimize or maximize its impact as needed.

Future Thread: Printing Electronics on Fibers.

This article introduces a methodology to increase the integration density of functional electronic features on fibers/threads/wires through additive deposition of functional materials via printed electronics. It opens the possibility to create a multifunctional intelligent system on a single fiber/thread/wire while combining the advantages of existing approaches, i.e., the scalability of coating techniques and the microfeatures of semiconductor-based fabrication. By directly printing on threads (of diameters ranging from 90 to 1000 μm), micropatterned electronic devices and multifunctional electronic systems could be formed. Contact and noncontact printing methods were utilized to create various shapes from serpentines and meanders to planar coils and interdigitated electrodes, as well as complex multilayer structures for thermal and light actuators, humidity, and temperature sensors. We demonstrate the practicality of the method by integrating a multifunctional thread into a FFP mask for breath monitoring. Printing technologies provide virtually unrestricted choices for the types of threads, materials, and devices used. They are scalable via roll-to-roll processes and offer a resource-efficient way to democratize electronics across textile products.

Potential monitoring during Ge electrochemical etching: Towards tunable double porosity layers

Porous Germanium (PGe) has emerged as a promising material for applications such as substrate engineering, sensing, and energy storage, thanks to its uniquely versatile and tunable properties. The bipolar electrochemical etching (BEE) method is widely regarded as the go-to approach for producing high-quality PGe layers. However, the lack of profound understanding of BEE process limits its use to a few well-studied morphological structures, hindering the development of more complex multi-layered structures with variable morphologies. In this work, we introduce potentiometric measures of the system as a means of monitoring the BEE process. We establish a correlation between the potential response and the reactions occurring during the BEE process, as well as their evolution over time. This approach enables elucidating the importance of the passivation, and how to shape the double-layered PGe structures. These findings bring new opportunities for controllable BEE with process monitoring and fabrication of tunable PGe multilayers for advanced applications.

Micro-/nanohoneycomb-like porous silicon loaded with Ag particles leads to synergistic enhancement of photothermal and thermoelectric conversions for MEMS thermopile chip application

Infrared detection technology has extensive and important applications in both military and civilian fields. Due to the advantages including no refrigeration, wide spectral response range, no chopping, low cost, and simple output circuit, MEMS thermopile chip has become one of the research hotspots in the field of infrared detection. The working mode of the thermopile chip is based on the photothermal and thermoelectric conversions, which are achieved by the infrared absorber and thermocouples, respectively. Actually, the resulting complex multi-layer structure brings about the shortcomings of thermopile chips, such as large heat capacity, large loss of heat transfer, low stacking efficiency and long response time, which has become the bottleneck of performance improvement. This work proposes a new concept for achieving high-efficiency photothermal and thermoelectric conversions of the thermopile chip simultaneously by a monolayer of multi-functional material. Herein, a micro-/nanohoneycomb-like porous Si loaded with Ag particles was constructed by metal-assisted chemical etching. The etched Si/Ag was endowed with high-efficiency light absorption in a wide spectral range (2–20 µm) and thermoelectric conversion, with the help of synergistic effect of light trapping, phonon scattering, energy filtering, and plasmon resonance. Replacing the infrared absorption layer, thermocouple layer, and insulation layer of the thermopile chip by the as-constructed porous Si/Ag composite can significantly reduce the heat capacity and energy transfer loss of the chip. It is expected to acquire a leap in the performance of the thermopile infrared detectors, providing a new technical approach for breaking through the bottleneck of small-scale and high-performance thermopile chips.

Mixed-Mode Magic-Ts and Their Applications on the Designs of Dual-Band Balanced Out-of-Phase Filtering Power Dividers

In this article, two types of mixed-mode magic-Ts are proposed, which can realize out-of-/in-phase equal power divisions of multiple mixed modes ports with high isolation, common-mode (CM) rejection, and compact size. The first one, which has five ports, consists of a microstrip T-junction as a single-ended-to-single-ended (SETSE) in-phase power division network, and a microstrip/slotline transition as a balanced-to-single-ended (BTSE) out-of-phase power division network. Through the analysis of scattering matrix, a high isolation is obtained in the mixed-mode magic-T. The second one, which consists of a single-ended-to-balanced (SETB) in-phase power division network based on a microstrip T-junction, and a balanced-to-balanced (BTB) out-of-phase power division network based on a slotline T-junction. Taking advantage of the two types of mixed-mode magic-Ts, a BTSE filtering power divider (FPD) and a BTB FPD are investigated, respectively. The characteristics of the mixed-mode magic-Ts make the proposed configurations unique, since most published balanced FPDs based on complex multi-layer structures to achieve miniaturization. The proposed FPDs are integrated with a pair of asymmetric shorted-stub-loaded resonators (ASSLRs). The expected frequencies and bandwidths of the two differential-mode (DM) passbands can be obtained by turning the parameters of ASSLRs. Meanwhile, multiple transmission zeros (TZs) can be generated to improve the passbands selectivity by employing multiple coupling paths. Besides, a high and broadband CM rejection can be generated by introducing U-type balanced port, which simplifies the design process considerably.

Flash joining of metal-ceramic multi-layered sandwich structure

The present study uses Flash joining technique to join sandwiched Titanium (Ti) metal with two pre-sintered Titanium dioxide (TiO2) pellets. This method employs Direct Current (DC) to enable rapid diffusion across stacked layers, due to Joule heating, resulting in reliable and continuous interface of the sandwich structure. Joining was found to be more uniform and continuous at lower current density, with respect to that at higher current densities. However, current direction has a detrimental effect on the anodic interface in comparison to the cathodic interface, resulting in superior mechanical properties at cathodic interface. This differential joining behaviour can be attributed to concentration of oxygen vacancies at the anodic interface. X-ray Photoelectron Spectroscopy and Raman, indicating higher concentration of oxygen vacancies at anodic interface, support this notion. The study reveals the directional effect of the current on joining ceramics to metals to attain superior structural integrity for complex multi-layered sandwich structures.

Pharmaceutical blister waste recycling using biogenic sulfuric acid: Effect of sulfur source and blister material on bioleaching efficiency

Several thousand tons of plastic are produced globally for pharmaceutical blister packages every year, leading to an expected consumption of over 2.8 million tons by 2026. Comprising a complex multilayer structure, blisters cannot be recycled in conventional recycling processes, leading to a loss of aluminium and valuable polymers during incineration and landfilling. As a promising secondary source of aluminium, new recycling strategies need to be developed to selectively separate the different layers. In this study, three types of blister packaging materials consisting of 13–68% (w/w) aluminium were investigated regarding aluminium and polymer recovery by using biogenic sulfuric acid for bioleaching. Waste elemental sulfur from biogas desulfurisation was assessed for biogenic sulfuric acid production by the two sulfur-oxidizing bacteria Acidithiobacillus thiooxidans and Acidithiobacillus caldus and compared to commercial elemental sulfur. For biogenic sulfur, higher sulfate production yield (320 mM), lower pH-value (pH = 0.56) and complete sulfur oxidation within 14 days was observed when compared to commercial sulfur. Application of a more concentrated biogenic acid (pH = 0.22) led to more effective and complete (∼100%) aluminium bioleaching up to 7.5% (w/v) blister waste within 7–9 days of incubation compared to 83% and 63% chemical leaching efficiency of transparent and white blisters using commercial sulfuric acid at the same pH, respectively. In addition, the plastic fraction after bioleaching was characterized and tested regarding re-processability. Results showed that sulfur from a biological origin can be oxidized faster by bacteria and biogenic acid is more effective in aluminium bioleaching compared to commercial sulfuric acid. Furthermore, results indicated that the plastic material is suitable for re-processing making this process an economically and environmentally friendly treatment option.

Deterministic Current‐Induced Perpendicular Switching in Epitaxial Co/Pt Layers without an External Field

AbstractCurrent‐induced spin‐orbit torques (SOTs) have emerged as a powerful tool to control magnetic elements and non‐uniform magnetic textures such as domain walls and skyrmions. SOT‐induced switching of perpendicular magnetization generally requires an external field to break the rotational symmetry of the spin‐orbit effective fields responsible for the deterministic reversal. The proposed mechanisms to eliminate this requirement often rely on complex multilayer structures that necessitate laborious optimization in the material and spin transport properties, making them less attractive for applications. Herein, current‐induced, external field‐free switching of an epitaxial MgO/Pt/Co trilayer with an extremely large perpendicular anisotropy in excess of 3 Tesla is reported. It is found that switching occurs due to the interplay of strong SOTs, local anisotropy fluctuations, and the Dzyaloshinkii‐Moriya interaction inherent to this epitaxial system. Given that these layers constitute the base stack of a magnetic tunnel junction, this switching mechanism offers the most technologically viable path toward devices such as field‐free SOT‐based magnetic random‐access memories.

WATER PRODUCTION ISOLATION TECHNIQUES FOR OIL-WELLS WITH HIGH RESERVOIR TEMPERATURE

Advanced drilling technology makes it possible to penetrate oil and gas sites with deep bedding of oil reservoir, a complex multi-layer structure and a high reservoir temperature at the well bottom, reaching 150°C. The difficult geology of oil strata leads to the fact that the productive layers of a well are flooded unevenly. In this work the causes for water cut in reservoirs are given, repair and insulation work and technologies for isolation of water-bearing intervals in the oil-producing wells considered. Grouting composites for water inflow limitation in reservoirs with low temperature (up to 100°C) and high-temperature reservoirs are studied. For water flood control in the oil and gas wells with high temperature viscoelastic composites with extended gel-time and high stable strength and adhesive properties has been proposed. The advantage of polymer-based composites is their kinetic behavior in dynamic mode, when filtering in a porous medium, which makes it possible to isolate effectively intake formations with different channel openings with a small flow rate of the mixture.

3D bioprinting of complex tissue scaffolds with in situ homogeneously mixed alginate-chitosan-kaolin bioink using advanced portable biopen

Control of in situ 3D bioprinting of hydrogel without toxic crosslinker is ideal for tissue regeneration by reinforcing and homogeneously distributing biocompatible reinforcing agent during fabrication of large area and complex tissue engineering scaffolds. In this study, homogeneous mixing, and simultaneous 3D bioprinting of a multicomponent bioink based on alginate (AL)-chitosan (CH), and kaolin was obtained by an advanced pen-type extruder to ensure structural and biological homogeneity during the large area tissue reconstruction. The static, dynamic and cyclic mechanical properties as well as in situ self-standing printability significantly improved with the kaolin concentration for AL-CH bioink-printed samples due to polymer-kaolin nanoclay hydrogen bonding and cross-linking with less amount of calcium ions. The Biowork pen ensures better mixing effectiveness for the kaolin-dispersed AL-CH hydrogels (evident from computational fluid dynamics study, aluminosilicate nanoclay mapping and 3D printing of complex multilayered structures) than the conventional mixing process. Two different cell lines (osteoblast and fibroblast) introduced during large area multilayered 3D bioprinting have confirmed the suitability of such multicomponent bioinks for in vitro even tissue regeneration. The effect of kaolin to promote uniform growth and proliferation of the cells throughout the bioprinted gel matrix is more significant for this advanced pen-type extruder processed samples.