Complex Gastrointestinal Procedures Research Articles

Improving ERCP quality and decreasing risk to patients and providers

Endoscopic retrograde cholangiopancreatography (ERCP) continues to be one of the most complex gastrointestinal procedures and carries the highest risk of complications. Optimizing the outcome of ERCP requires a fine balance between the risk and the benefit of every maneuver performed. This fine balance has to include an analysis of the indication for the procedure, the optimal timing, the setting where the procedure is performed, the endoscopist and staff training and expertise, availability of surgical and interventional radiology support, the risk of every maneuver and ways to minimize this risk. As in any other procedure, it is very important to know one’s limitations and have a plan for failed procedures including consulting a colleague or referring the patient to a center with more expertise. In addition, a process of quality improvement is integral to every endoscopy center to address areas of underperformance, improve patient care and decrease liability.

Mo1464 Impact of Operative Duration on Postoperative Pulmonary Complications Among Patients Undergoing Complex Gastrointestinal Procedures

Cr>2.0 (aOR 1.99, 95% CI :1.33-2.93), WBC between 10-20 (aOR 1.44, 95% CI:1.131.81), moderate exertional dyspnea (aOR 1.94, 95% CI: 1.47-2.53), and ASA status greater than 3 (aOR 1.79, 95%CI:1.53-2.10). Colostomy reversal was also associated with higher odds of overall morbidity (aOR 1.28, 95% CI:1.08-1.50) and wound infections (aOR 1.70, 95%CI :1.39-2.07). Conclusion: Colostomy reversal is associated with increased overall morbidity, wound infections, and nearly twice the operative time compared to ileostomy reversal. These factors should be considered when deciding which type of diverting stoma to perform.

Early Tracking Would Improve the Operative Experience of General Surgery Residents

High surgical complexity and individual career goals has led most general surgery (GS) residents to pursue fellowship training, resulting in a shortage of surgeons who practice broad-based general surgery. We hypothesize that early tracking of residents would improve operative experience of residents planning to be general surgeons, and could foster greater interest and confidence in this career path. Surgical Operative Log data from GS and fellowship bound residents (FB) applying for the 2008 American Board of Surgery Qualifying Examination (QE) were used to construct a hypothetical training model with 6 months of early specialization (ESP) for FB residents in 4 specialties (cardiac, vascular, colorectal, pediatric); and presumed these cases would be available to GS residents within the same program. A total of 142 training programs had both FB residents (n = 237) and GS residents (n = 402), and represented 70% of all 2008 QE applicants. The mean numbers of operations by FB and GS residents were 1131 and 1091, respectively. There were a mean of 252 cases by FB residents in the chief year, theoretically making 126 cases available for each GS resident. In 9 defined categories, the hypothetical model would result in an increase in the 5-year operative experience of GS residents (mastectomy 6.5%; colectomy 22.8%; gastrectomy 23.4%; antireflux procedures 23.4%; pancreatic resection 37.4%; liver resection 29.3%; endocrine procedures 19.6%; trauma operations 13.3%; GI endoscopy 6.5%). The ESP model improves operative experience of GS residents, particularly for complex gastrointestinal procedures. The expansion of subspecialty ESP should be considered.

Relationship Between Hospital Volume, System Clinical Resources, and Mortality in Pancreatic Resection

The relationship between hospital volume and perioperative mortality in pancreaticoduodenectomy has been well established. We studied whether associations exist between hospital volume and hospital clinical resources and between both of these factors to mortality to help explain this relationship. This two-part study reviewed publicly available hospital information from the Leapfrog Group, HealthGrades, and hospital Web sites. Hospitals were evaluated for Leapfrog ICU staffing criteria and Safe Practice Score; HealthGrades five-star rating for complex gastrointestinal procedures and operations; and presence of a general surgery residency, gastroenterology fellowship, and interventional radiology. Evaluation used trend analysis and multiple logistic regression analysis. The second part determined the mortality rate for pancreaticoduodenectomy using inpatient mortality data from the National Inpatient Sample and Leapfrog. Hospitals were categorized by low volume (< or = 10/year), high volume (> or = 11/year), strong clinical support (presence of all support factors), and weak clinical support (absence of any factor). Data were correlated by number of pancreatic resections per hospital, hospital system clinical resources, and operative mortality. As hospital volume increased, statistically significant increases occurred in the frequency of hospitals meeting Leapfrog ICU staffing criteria (p < 0.0001), Leapfrog Safe Practice Score (p = 0.0004), HealthGrades 5-star rating (p < 0.00001), general surgery residency (p < 0.00001), gastroenterology fellowship (p < 0.00001), and interventional radiology services (p < 0.00001). No significant relationships were found between resection volume and any one of the clinical support factors and perioperative death. Presence of strong clinical support was associated with lower mortality (odds ratio = 0.32; p = 0.001). System clinical resources were more influential in operative mortality for pancreatic resection. This might help explain why high-volume hospitals, low-volume surgeons in high-volume institutions, and some lower-volume hospitals with excellent clinical resources have lower perioperative mortality rates for pancreatic resection.

Laparoscopic Colectomy for Colon Cancer: Comparable to Conventional Oncologic Surgery?

As a result of the obvious benefits of laparoscopic cholecystectomy, minimally invasive techniques have been applied to more complex gastrointestinal procedures, including colorectal resections. The goal in adapting laparoscopic techniques for colorectal surgery is to offer an operation that results in less pain, shorter hospital stay, more rapid return to normal activities, and improved cosmesis compared with conventional operation. The challenge has been to show that this can be done safely and efficiently and that for cancer patients there is no detrimental oncologic effect. The major issues that have been and continue to be addressed are (1) whether an adequate resection can be performed laparoscopically, (2) whether there is a high rate of wound or port site recurrence following these operations, and (3) whether, by using these techniques, we are trading short-term benefits for a poor long-term oncologic outcome. To answer these fundamental questions, several prospective randomized trials have been conducted and several more are under way. The results of these trials indicate that, in terms of cancer outcome, there is no difference in overall survival, disease-free survival, and wound recurrences in patients treated using laparoscopic techniques compared with conventional operation. In addition, there are short-term benefits associated with the use of these techniques. It can now be said that from an oncologic standpoint, in experienced hands, laparoscopic colectomy for curable colon cancer is equivalent to conventional therapy, and it is superior to conventional operation regarding short-term outcomes. Laparoscopic colectomy for colon cancer should be offered to appropriately selected patients.