Compatible Hypotheses Research Articles

Determinants of microbiome composition: Insights from free-ranging hybrid zebras (Equus quagga × grevyi).

The composition of mammalian gut microbiomes is highly conserved within species, yet the mechanisms by which microbiome composition is transmitted and maintained within lineages of wild animals remain unclear. Mutually compatible hypotheses exist, including that microbiome fidelity results from inherited dietary habits, shared environmental exposure, morphophysiological filtering and/or maternal effects. Interspecific hybrids are a promising system in which to interrogate the determinants of microbiome composition because hybrids can decouple traits and processes that are otherwise co-inherited in their parent species. We used a population of free-living hybrid zebras (Equus quagga × grevyi) in Kenya to evaluate the roles of these four mechanisms in regulating microbiome composition. We analysed faecal DNA for both the trnL-P6 and the 16S rRNA V4 region to characterize the diets and microbiomes of the hybrid zebra and of their parent species, plains zebra (E. quagga) and Grevy's zebra (E. grevyi). We found that both diet and microbiome composition clustered by species, and that hybrid diets and microbiomes were largely nested within those of the maternal species, plains zebra. Hybrid microbiomes were less variable than those of either parent species where they co-occurred. Diet and microbiome composition were strongly correlated, although the strength of this correlation varied between species. These patterns are most consistent with the maternal-effects hypothesis, somewhat consistent with the diet hypothesis, and largely inconsistent with the environmental-sourcing and morphophysiological-filtering hypotheses. Maternal transmittance likely operates in conjunction with inherited feeding habits to conserve microbiome composition within species.

The Induction of Religious Experiences and Temporal Lobe Activation: Neuronal Source Localization Using EEG Inverse Solutions

Knowledge about brain source localizations for religious states of mind is still limited. Previous studies have usually not set a direct emphasis on experience. The present study investigated the phenomenon of religious experience using inverse solution calculations, and it is one of the first to measure the dimension of experience directly. A total of 60 evangelical Christians participated in an experiment where they were asked to engage in worship and try to connect with God. Using a bar slider, the participants continuously rated how strongly they sensed God’s presence at any given moment. A selection of songs helped to induce the desired experience. Measurements were made using EEG with 64 electrodes and inverse solutions were calculated with sLORETA. We appropriated two mutually compatible hypotheses from the literature pertaining to religious experiences: the executive inhibition hypothesis (reformulated as the frontal relaxation hypothesis) and the temporal involvement hypothesis. Our results did not yield any information about the frontal areas; however, they indicated that the right temporal cortex appeared to be involved during the experience.

Sherlock Holmes and the Case of Resist/Refuse Dynamics: Confirmatory Bias and Abductive Inference in Child Custody Evaluations

Had Sir Arthur Conan Doyle's fictional detective, the great Sherlock Holmes, actually engaged in deductive reasoning, he would have solved many fewer crimes. In fact, Holmes' logical progression from astute observation to hypotheses is a model of a type of inductive reasoning. This paper argues that mental health professionals tasked to evaluate why a child is resisting/refusing contact with one parent must approach each family the way that Holmes approached each case, without a presumed suspect, moving systematically from detail to hypothesis, well‐versed in the full range of dynamics that may be at play, and erring in favor of parsimony rather than pathology. By contrast, the custody evaluator who approaches these matters through a deductive process, seeking data that support an a priori theory, is vulnerable to confirmatory bias and doing harm to the child whose interests are paramount. The literature concerned with resist/refuse dynamics is reviewed, yielding 13 non‐mutually exclusive variables that evaluators must consider so as to more fully identify why a particular child is resisting or refusing contact with one parent. On this basis, the hybrid model is expanded to include the full spectrum of contributing dynamics. Specific recommendations are made for judicial officers in the interest of writing orders for custody evaluations that minimize the risk of confirmatory bias.Key Points for the Family Court Community Deductive reasoning seeks to confirm or refute an a priori hypothesis Deductive reasoning is highly vulnerable to confirmational bias Confirmational bias can corrupt and invalidate forensic evaluation to the detriment of all involved Resist/refuse dynamics must be understood through an inductive process that is open to all possible hypotheses A survey of the literature identifies at least thirteen mutually compatible hypotheses, all of which must be evaluated Courts must take care to word orders for forensic family evaluations in a manner that minimizes confirmatory bias and invites inductive investigation

Rethinking with Demons: The Campaign against Superstition in Late Medieval and Early Modern Europe from a Cognitive Perspective

ABSTRACT Popular religion in late medieval and early modern Europe posited an invisible world densely populated with both personal spirits and impersonal forces that interacted constantly with the natural and social realms in ambiguous and unpredictable ways. This represented a stark contrast to elite theological discourse, which insisted on dividing the spirit world into a strict moral dichotomy of good and evil spirits, operating within a rigid causal taxonomy of natural, preternatural, and supernatural. During this period, deviations from this elite theological consensus were increasingly labeled “superstitious.” The cognitive science of religion postulates that beliefs about demons and spirits are constrained by the evolved cognitive architecture of our species, and in this article I show that the patterns of religious belief and practice targeted by the critics of superstition are compatible wth key hypotheses in the cognitive science of religion.

Genes and Group Membership Predict Gidgee Skink (Egernia stokesii) Reproductive Pairs.

Due to their role in mate choice, disease resistance and kin recognition, genes of the major histocompatibility complex (MHC) are good candidates for investigating genetic-based mate choice. MHC-based mate choice is context dependent and influenced by many factors including social structure. Social structure diversity makes the Egernia group of lizards suitable for comparative studies of MHC-based mate choice. We investigated mate choice in the gidgee skink (Egernia stokesii), a lizard that exhibits high levels of social group and spatial stability. Group membership was incorporated into tests of the good genes as heterozygosity and compatible genes hypotheses for adaptive (MHC) and neutral (microsatellite) genetic diversity (n = 47 individuals genotyped). Females were more likely to pair with a male with higher MHC diversity and with whom they had a lower degree of microsatellite relatedness. Males were more likely to pair with a female with higher microsatellite heterozygosity and with whom they shared a lower proportion of MHC alleles. Lizards were more likely to mate with an individual from within, rather than outside, their social group, which confirmed earlier findings for this species and indicated mate choice had already largely occurred prior to either social group formation or acceptance of an individual into an existing group. Thus, a combination of genes and group membership, rather than group membership alone, predicted mate choice in this species. This work will contribute to an enhanced understanding of squamate group formation and a deeper understanding of the evolution of sociality within all vertebrates.

Biogeochemical drivers of Neotropical ant activity and diversity

AbstractHuman activities are rapidly changing biogeochemistry across the globe, yet little is known about biogeochemical impacts on higher‐level consumers. In a Panamanian rainforest, we measured the effects of chronic nitrogen, phosphorus, and potassium fertilization on ants: hyper‐abundant terrestrial arthropods and ecosystem engineers. We tested two compatible hypotheses: the nutrient limitation hypothesis—where adding a limiting nutrient increases ant activity and abundance; and the community homogenization hypothesis—where adding a limiting nutrient decreases ant diversity. Lowland tropical rainforests are expected to be phosphorus‐limited, so we predicted higher ant activity but lower diversity on phosphorus plots. In each fertilization plot, we baited trees and lianas to attract both canopy and ground nesting ants. After controlling for temperature, which accounted for roughly 20% of the variation in ant foraging activity, ant activity remained higher on phosphorus addition plots than on any other fertilization treatment. Genus level diversity was 16% lower on plots receiving phosphorus than the control, consistent with the paradox of enrichment frequently observed in plant communities. This pattern, however, did not hold for species level diversity. The community‐level response was largely driven by the most abundant genus, Azteca, which increased foraging activity and abundance across phosphorus plots. The high activity and low diversity of ants on experimental phosphorus plots point to the potentially strong influence of biogeochemistry on these ubiquitous insects with potential ramifications for the forest food web. This is, to our knowledge, the first study relating biogeochemistry of macronutrients to foraging activity, diversity, and abundance of consumers, implicating strong bottom‐up structuring of the ant community in one of the world's most diverse ecosystems.

The Effect of Incidental Semantic Activation on Hypothesis Generation: Exclusive vs Compatible Hypotheses

The Effect of Incidental Semantic Activation on Hypothesis Generation: Exclusive vs Compatible Hypotheses

Size, seasonality, or salinity: What drives the protistan species maximum in the horohalinicum?

The protistan species maximum concept for the challenging zone of critical salinity 5–8 (the horohalinicum) where the large benthic organisms experience the destructive osmotic stress has developed smoothly into the understanding that in the environment with sharp salinity fluctuations community regulations and life strategies of small unicellular planktonic organisms differ substantially from those of large multicellular bottom-dwellers. This inductive supposition has initiated efforts to define the major organismal traits and environmental factors that might be responsible for the new biodiversity pattern. There also emerged a need to better relate the novel conceptual assertions with the ‘field/pooled data paradox’ – a controversy when the pooled long-term large-scale datasets provide results which seem to contradict the field observations. This paper uses a long-term (1972–2006) phytoplankton dataset from the Baltic Sea for testing three new compatible research hypotheses by means of correlation analysis, non-metric multi-dimensional scaling using a Bray–Curtis dissimilarity matrix, and the rarefaction analysis. Hypothesis 1 argues that the smaller and therefore the faster evolving unicellular organisms are taxonomically more diverse in the horohalinicum than in the other sectors of the salinity gradient. Hypothesis 2 suggests that the recently discovered biodiversity pattern may be caused by a pronounced seasonality within the horohalinicum which might promote the shift in plankton community composition towards dominance of small-sized species in the critical salinity regions. Hypothesis 3 proposes that the protistan species maximum in the horohalinicum is largely backed up by the significant between-sample variation in highly changeable brackish-water environment rather than by within-sample species richness. Our results provided statistical proof that algal cell size minimum underpins the protistan species maximum in the horohalinicum, and supported all three research hypotheses.

Memory activation of multiple hypotheses in sequential diagnostic reasoning

In sequential diagnostic reasoning, observed evidence activates hypotheses about possible causes in memory. These memory activations have been previously examined with a probe reaction task for problems with a single correct diagnosis. We applied this process tracing method to ambiguous problems with multiple compatible hypotheses. When participants reasoned about the causes of ambiguous symptom sequences, they were prompted to respond to probes representing hypotheses. The response time to a probe was shorter if the current support for the respective hypothesis was stronger indicating that the processing of compatible hypotheses can be traced. For sequences with two equally supported hypotheses, the initial hypothesis was more often chosen as the final diagnosis (a primacy effect). Probe reaction times suggest that the initial hypothesis has been activated more strongly already early, when it was finally chosen as the diagnosis. Nevertheless, substantial variance in response times limits the task's applicability for process tracing.

The meaning of 'life' and other abstract words: Insights from neuropsychology.

There are a number of long‐standing theories on how the cognitive processing of abstract words, like ‘life’, differs from that of concrete words, like ‘knife’. This review considers current perspectives on this debate, focusing particularly on insights obtained from patients with language disorders and integrating these with evidence from functional neuroimaging studies. The evidence supports three distinct and mutually compatible hypotheses. (1) Concrete and abstract words differ in their representational substrates, with concrete words depending particularly on sensory experiences and abstract words on linguistic, emotional, and magnitude‐based information. Differential dependence on visual versus verbal experience is supported by the evidence for graded specialization in the anterior temporal lobes for concrete versus abstract words. In addition, concrete words have richer representations, in line with better processing of these words in most aphasic patients and, in particular, patients with semantic dementia. (2) words place greater demands on executive regulation processes because they have variable meanings that change with context. This theory explains abstract word impairments in patients with semantic‐executive deficits and is supported by neuroimaging studies showing greater response to abstract words in inferior prefrontal cortex. (3) The relationships between concrete words are governed primarily by conceptual similarity, while those of abstract words depend on association to a greater degree. This theory, based primarily on interference and priming effects in aphasic patients, is the most recent to emerge and the least well understood. I present analyses indicating that patterns of lexical co‐occurrence may be important in understanding these effects.

Ammonium metabolism enzymes aid Helicobacter pylori acid resistance.

The gastric pathogen Helicobacter pylori possesses a highly active urease to support acid tolerance. Urea hydrolysis occurs inside the cytoplasm, resulting in the production of NH3 that is immediately protonated to form NH4 (+). This ammonium must be metabolized or effluxed because its presence within the cell is counterproductive to the goal of raising pH while maintaining a viable proton motive force (PMF). Two compatible hypotheses for mitigating intracellular ammonium toxicity include (i) the exit of protonated ammonium outward via the UreI permease, which was shown to facilitate diffusion of both urea and ammonium, and/or (ii) the assimilation of this ammonium, which is supported by evidence that H. pylori assimilates urea nitrogen into its amino acid pools. We investigated the second hypothesis by constructing strains with altered expression of the ammonium-assimilating enzymes glutamine synthetase (GS) and glutamate dehydrogenase (GDH) and the ammonium-evolving periplasmic enzymes glutaminase (Ggt) and asparaginase (AsnB). H. pylori strains expressing elevated levels of either GS or GDH are more acid tolerant than the wild type, exhibit enhanced ammonium production, and are able to alkalize the medium faster than the wild type. Strains lacking the genes for either Ggt or AsnB are acid sensitive, have 8-fold-lower urea-dependent ammonium production, and are more acid sensitive than the parent. Additionally, we found that purified H. pylori GS produces glutamine in the presence of Mg(2+) at a rate similar to that of unadenylated Escherichia coli GS. These data reveal that all four enzymes contribute to whole-cell acid resistance in H. pylori and are likely important for assimilation and/or efflux of urea-derived ammonium.

The Sphex story: How the cognitive sciences kept repeating an old and questionable anecdote

The Sphex story is an anecdote about a female digger wasp that at first sight seems to act quite intelligently, but subsequently is shown to be a mere automaton that can be made to repeat herself endlessly. Dennett and Hofstadter made this story well known and widely influential within the cognitive sciences, where it is regularly used as evidence that insect behavior is highly rigid. The present paper discusses the origin and subsequent empirical investigation of the repetition reported in the Sphex story. The repetition was first observed by Henri Fabre in 1879, and the last empirical study I found was published in 1985. In contrast to the story's clear message, the actual results have always been equivocal: the endless repetition is not standard. In addition, this repetition itself has become a minor aside in the literature on digger wasps when put in the perspective of many other examples of adaptiveness and flexibility. Nevertheless, the story and its message have to this day persevered within the cognitive sciences. For some reason, the counterevidence has been neglected time and again. The paper closes by presenting two different but compatible hypotheses that could explain why humans keep repeating this particular anecdote.

New validation algorithm for data association in SLAM

In this work, a novel data validation algorithm for a single-camera SLAM system is introduced. A 6-degree-of-freedom monocular SLAM method based on the delayed inverse-depth (DI-D) feature initialization is used as a benchmark. This SLAM methodology has been improved with the introduction of the proposed data association batch validation technique, the highest order hypothesis compatibility test, HOHCT. This new algorithm is based on the evaluation of statistically compatible hypotheses, and a search algorithm designed to exploit the characteristics of delayed inverse-depth technique. In order to show the capabilities of the proposed technique, experimental tests have been compared with classical methods. The results of the proposed technique outperformed the results of the classical approaches.

Batch Gating for Data Association in Monocular SLAM

This work describes the development and implementation of a single-camera SLAM system, introducing a novel data validation algorithm. A 6-DOF monocular SLAM method developed is based on the Delayed Inverse-Depth (DI-D) Feature Initialization, with the addition of a new data association batch validation technique, the Highest Order Hypothesis Compatibility Test, HOHCT. The DI-D initializes new features in the system defining single hypothesis for the initial depth of features by stochastic triangulation. The HOHCT is based on evaluation of statistically compatible hypotheses, and search algorithm designed to exploit the Delayed Inverse-Depth technique characteristics. Experiments with real data are presented in order to validate the performance of the system.

Scientific Concepts and Their Policy Affordances: How a Focus on Compatibility Can Improve Science-Policy Interaction and Outcomes

We develop a twofold approach to the development and utilization of policy-relevant knowledge. First, we propose that moving beyond competition to focus on compatibility may promote more effective interdisciplinary collaborations in the context of complex social-ecological problems. Second, we propose that attention to the policy affordances of a set of compatible hypotheses may inform the development of a more holistic and robust set of policy options. This twofold approach is modeled in our methodological approach, in which we have sought to discover how the concepts each of us have been developing are compatible with each other, and what affordances they might offer for improving translation across the science-policy boundary. We illustrate and apply our approach to the complex milieu surrounding the issue of lead paint toxicity. In addition, we draw on findings from focus groups with researchers involved in collaborations at the science-policy boundary to develop recommendations for productive and policy-relevant interdisciplinary collaboration.

A Highest Order Hypothesis Compatibility Test for Monocular SLAM

Simultaneous Location and Mapping (SLAM) is a key problem to solve in order to build truly autonomous mobile robots. SLAM with a unique camera, or monocular SLAM, is probably one of the most complex SLAM variants, based entirely on a bearing-only sensor working over six DOF. The monocular SLAM method developed in this work is based on the Delayed Inverse-Depth (DI-D) Feature Initialization, with the contribution of a new data association batch validation technique, the Highest Order Hypothesis Compatibility Test, HOHCT. The Delayed Inverse-Depth technique is used to initialize new features in the system and defines a single hypothesis for the initial depth of features with the use of a stochastic technique of triangulation. The introduced HOHCT method is based on the evaluation of statistically compatible hypotheses and a search algorithm designed to exploit the strengths of the Delayed Inverse-Depth technique to achieve good performance results. This work presents the HOHCT with a detailed formulation of the monocular DI-D SLAM problem. The performance of the proposed HOHCT is validated with experimental results, in both indoor and outdoor environments, while its costs are compared with other popular approaches.

The framing of games and the psychology of play

Psychological game theory can provide rational-choice-based framing effects; frames influence beliefs, beliefs influence motivations. We explain this theoretically and explore empirical relevance experimentally. In a 2 × 2 design of one-shot public good games we show that frames affect subjectʼs first- and second-order beliefs and contributions. From a psychological game-theoretic framework we derive two mutually compatible hypotheses about guilt aversion and reciprocity under which contributions are related to second- and first-order beliefs, respectively. Our results are consistent with either.

Celebrities: From Teachers to Friends : A Test of Two Hypotheses on the Adaptiveness of Celebrity Gossip.

In this paper we present two compatible hypotheses to explain interest in celebrity gossip. The Learning Hypothesis explains interest in celebrity gossip as a by-product of an evolved mechanism useful for acquiring fitness-relevant survival information. The Parasocial Hypothesis sees celebrity gossip as a diversion of this mechanism, which leads individuals to misperceive celebrities as people who are part of their social network. Using two preliminary studies, we tested our predictions. In a survey with 838 respondents and in-depth interviews with 103 individuals, we investigated how interest in celebrity gossip was related to several dimensions of the participants' social lives. In support of the Learning Hypothesis, age proved to be a strong predictor of interest in celebrities. In partial support of the Parasocial Hypothesis, media exposure, but not social isolation, was a strong predictor of interest in celebrities. The preliminary results support both theories, indicate that across our life span celebrities move from being teachers to being friends, and open up a list of future research opportunities.

On the uninterpretability of dual-task performance

In this commentary, we argue that dual-task performance is currently not interpretable. The argument is based on the assumption that a number of plausible and compatible hypotheses have been offered to account for dual-task interference. Our present state of theoretical development does not permit us to discriminate among the alternative hypotheses. We demonstrate this by constructing a simple linear model which includes only limited resources and response competition. In order to fit this model, a minimum of eight groups must be run and single- and dual-tasks must be scaled on the same dimension.

Polyhedra Recognition by Hypothesis Accumulation

A new method is presented for the recognition of polyhedra in range data. The method is based on a hypothesis accumulation scheme which allows parallel implementations. The different objects to be recognized are modeled by a set of local geometrical patterns. Local patterns of the same nature are extracted from the scene. For the recognition of an object, local scene and model patterns having the same geometrical characteristics are matched. For each of the possible matches, the geometric transformations (i.e., rotations and translations) are computed, which allows the overlapping of the model elements with those from the scene. This transformation permits the establishment of a hypothesis on the location of the object in the scene and the determination of a point in the transformation space. The presence of an object similar to a model involves the generation of several compatible hypotheses and creates a compact cluster in the transformation space. The recognition of the object is based on the detection of this cluster. The cluster coordinates give the values of the rotations and the translations to be applied to the model such that it corresponds to the object in the scene. The exact location of this object is given by the transformed model.