Comparison Of Histopathological Findings Research Articles

Comparison of Histopathologic Findings with Patterns of Immunofluorescence Staining in Native Kidney Biopsies Diagnostic for IgA Nephropathy

Comparison of Histopathologic Findings with Patterns of Immunofluorescence Staining in Native Kidney Biopsies Diagnostic for IgA Nephropathy

Comparison of Histopathological Findings in Psoriasis According to the Lesion Location From Biopsy.

The aim of this study was to investigate whether the histopathological findings of psoriasis varied by the biopsied lesion location. Age, gender, age at disease onset, lesion locations, presence or absence of a preliminary diagnosis of psoriasis, and histopathological findings of 307 patients were recorded. The sections prepared from the patients' paraffin blocks were reexamined microscopically, the severity of the observed findings was graded, and various histopathological features were recorded. The female-to-male ratio was 1.2 to 1. Family history for psoriasis was positive in 30% of patients. A clinically preliminary diagnosis of psoriasis was present in 232 patients. The most common histopathological features included hyperkeratosis, parakeratosis, Munro/Kogoj microabscesses, suprapapillary thinning-hypogranulosis, and vascular dilation-capillary proliferation. Hyperkeratosis was least common in the trunk. A linear and moderately strong correlation was found between the histopathological findings of inflammation, capillary proliferation, and suprapapillary thinning. For the first time, the clinical and demographic features of psoriasis are evaluated and the severity of the histopathological findings is compared by the biopsied lesion location in a large number of patients.

Comparison of Histopathological Findings with Clinical Response among Patients Undergoing Consecutive Renal Biopsy for Lupus Nephritis in 2008-2021

Comparison of Histopathological Findings with Clinical Response among Patients Undergoing Consecutive Renal Biopsy for Lupus Nephritis in 2008-2021

Comparison of Histopathologic Findings with BIRADS Score in Trucut Biopsies of Breast Lesions

Comparison of Histopathologic Findings with BIRADS Score in Trucut Biopsies of Breast Lesions

Endometrial health and disease in the mare – Comparison of histopathological findings and microbiological results of two different culture methods: uterine swab and endometrial tissue

Endometrial health and disease in the mare – Comparison of histopathological findings and microbiological results of two different culture methods: uterine swab and endometrial tissue

Comparison of Histopathologic Findings in Duodenal and Ileal Endoscopic Biopsies in Dogs with Chronic Small Intestinal Enteropathies

The current tendency when investigating dogs with chronic upper gastrointestinal signs is to perform endoscopy and biopsy only the duodenum. This approach could lead to overlooking important ileal lesions and affect the clinical management. To compare concurrent duodenal and ileal endoscopic biopsies in dogs with chronic enteropathies and evaluate their correlation with clinicopathologic findings. Thirty-eight dogs with chronic enteropathies. Duodenal and ileal biopsies were retrospectively reviewed. Nine histologic variables, 5 structural (villous stunting, epithelial injury, crypt distension, lacteal dilatation, and mucosal fibrosis) and 4 inflammatory (intraepithelial lymphocytes, lamina propria lymphocytes and plasma cells, eosinophils, and neutrophils) were scored. Clinical severity scores and relevant clinicopathologic variables were evaluated. There was only slight agreement between duodenal and ileal histologic scores (κ=0.003). There was slight agreement between the presence of any of the morphological and inflammatory variables, with the exception of mucosal fibrosis (κ=0.44). Statistically significant correlation was found between clinical severity and duodenal crypt distension (P=.031), ileal lacteal dilatation (P=.038), and ileal mucosal lymphoplasmacytic inflammation (P=.035). A significant correlation was found between hypoalbuminemia and ileal lacteal dilatation (P=.033) and number of ileal intraepithelial lymphocytes (P=.019). A statistically significant correlation was found between hypocobalaminemia and number of ileal intraepithelial lymphocytes (P=.012). When investigating dogs with chronic upper gastrointestinal signs, the collection of concurrent duodenal and ileal endoscopic biopsies is recommended.

Comparison of Histopathological Findings with Duplex Sonography of the Temporal Arteries in Suspected Giant Cell Arteritis

In clinical practice the temporal artery biopsy (TAB) in suspected giant cell arteritis (GCA) is still believed to be the "gold standard". The purpose of this study was to compare the histopathological findings of the TAB with duplex sonography of the temporal artery. In our retrospective study we analysed 85 consecutive patients (52 female, mean age 71.5, range 55 - 91 years; 33 male, mean age 71.6, range 44 - 91 years) with suspected GCA who underwent TAB in our clinic between January 1999 - February 2011. All patients received a preoperative duplex sonography, 57 patients including description of the temporal arteries. 38 of 85 (44.7 %) of the artery biopsies were proven positive for GCA by histopathology. Interpretation of the duplex sonography was congruent of histopathological interpretation of the biopsy in 39 patients (68.4 %) and incongruent in 18 patients (31.6 %). Sensitivity of duplex-sonography was 44.4 %, specificity 90 %, positive predictive value 80 %. Duplex sonography is a non-invasive and very helpful diagnostic tool to guide the clinician in cases of suspected GCA but needs considerable skills. It shows a good specificity and relatively high positive predictive value as there are only few false positive results. A negative report however does not rule out GCA, so that in our opinion the TAB - at least in those cases - should still be performed.

Comparison of Histopathologic Findings in Biopsies from the Duodenum and Ileum of Dogs with Enteropathy

In the investigations of dogs with chronic small intestinal diarrhea collection of ileal biopsies lengthens procedural time and has been of uncertain value. To evaluate whether there was agreement between histologic changes present in samples of duodenal and ileal mucosa, and hence to provide initial information in the process of determining whether collection of ileal biopsies is clinically justified. 40 dogs with chronic small and large intestinal diarrhea from which endoscopic (in 30 cases) or surgical (in 10 cases) duodenal and ileal biopsies had been collected. Samples were reviewed concurrently by two observers (MJD and MDW) using the scoring system developed by the World Small Animal Veterinary Association (WSAVA) Gastrointestinal Standardization Group. Comparisons were made by kappa analysis. Microscopic pathology was observed in 30 cases. Only eight out of this 30 (27%) had the same histopathologic diagnosis in both the duodenum and the ileum. This dropped to 3 out of 30 (10%) if different disease severity was also considered as disagreement. Microscopic pathology would have been found in 60% and 80% of the 30 cases, if only duodenal or ileal biopsies respectively, had been available. There was poor agreement between histopathological findings from duodenal versus ileal biopsies with abnormalities sometimes being more readily detected in the ileum. Routine collection of ileal plus duodenal samples appears warranted when concurrent small and large intestinal diarrhea is present.