Chronic mental illness, especially schizophrenia, can lead to long-term disability, largely consequent upon the negative symptoms that persist. More than half of all patients with schizophrenia will suffer from residual disability. Depressing though this is, it is encouraging to note that in half of all patients, the mental symptoms decrease over time, and the patients are able to achieve some semblance of a normal life sometimes even a complete cure. A variety of factors seem to be implicated in the extent to which patients remain with deficits. Although genetics may play a part, it is recognized that social factors and periods of institutionalization may cause negative symptoms. This has important implications for rehabilitation and the prevention of relapse. It is especially important that community support programs and long-term rehabilitation efforts help to remedy or compensate for deficits in social skills. Even where institutionalization is uncommon, there are other psychosocial factors that produce the same effects. In many developing countries, a person is ostracized and stigmatized following an episode of ' 'madness, ' ' even if all symptoms have disappeared and the patient' s behavior has returned to normal. Expectations with regard to the person's role in society, a lack of trust in his judgment, and a generally negative attitude by others in the community can cause the former