Wildlife has the potential to support people’s livelihoods and economic development in many African countries. The objective of the review was to evaluate the potential contribution of wildlife to people’s livelihoods and economic development in Africa. Several databases were searched to identify articles that have explored the contributions of wildlife to people’s livelihoods and economic development. The results indicate that wildlife contributes both consumptive and non-consumptive resources towards people’s livelihoods, with bush meat being the greatest consumptive contribution and employment the greatest non-consumptive contribution. Revenue collected from tourists, trophy hunting, and game viewing have been used for infrastructure and rural development. However, wildlife has declined in many African countries due to land redistribution, drought, habitat fragmentation, human population growth, and illegal hunting. Setting up law enforcement agents and creating community-based wildlife management could restore the benefits of wildlife.