Common Health Problem Research Articles

An evaluation of the knowledge, attitudes and treatment approaches of general dental practitioners in Ireland in the management of traumatic dental injuries.

Traumatic Dental Injuries (TDIs) are a common oral health problem worldwide. Prompt and accurate diagnosis and treatment maximises the chances of favourable outcomes. This study aimed to evaluate the knowledge and attitudes of Irish Dentists regarding the management of TDIs based on different trauma scenarios. Following ethical approval, a cross-sectional, 22-item self-administered questionnaire was distributed electronically to members of the Irish Dental Association between January and March 2024. A total of 245 complete responses were obtained, representing a 17% response rate. The results demonstrated a correlation between self-reported knowledge and number of correct answers. Overall 80% of respondents chose the correct storage medium for avulsed teeth. The majority of dentists aged > 46 years were unaware of the updated IADT guidelines. A large proportion of dentists showed inadequate knowledge with regard to the management of intruded permanent teeth (65%) and the endodontic management of an immature avulsed permanent tooth (50%). Management of intruded teeth and knowledge of root fractures was not as good as other injury types. The majority of respondents (85%) correctly answered that a tooth with negative sensibility tests following subluxation does not require endodontic treatment immediately. The survey had an acceptable response rate and demonstrated overall good knowledge in the management of TDIs. However, there was still confusion over management of certain scenarios which could have negative repercussions for patients entering an unnecessary restorative cycle. There is a need to improve practitioner confidence and experience in the management of certain TDIs and improve awareness of the IADT guideline as a resource, especially in dentists with more years of experience.

Bacterial Etiology of Lower Respiratory Tract Infection that Isolated from Tripoli University Hospital (TUH) Units in 2019

Introduction: Lower respiratory tract infection (LRTI) is one of the common major health problems, causing morbidity and mortality. Aims: The study was conducted to determine the current trends of bacterial etiology of LRTIs among patients who attended the University Teaching Hospital (UTH) and their antimicrobial susceptibility profile with special interest on drug resistance. Study Design: The study was a Cross sectional study. All patients’ files were selected as diagnosed with LRTIs and their demographic data, other illness, prescribed treatment /antibiotic used previously. Place and Duration of Study: This study is designed to collect data from files of lower respiratory tract infection patients following in units of university hospital in Tripoli. Methodology: The study was conducted between January to December 2019. at the unit in university hospital in Tripoli city in Libya. Sputum samples of 465 patients with suspected LRTIs were received, after obtaining patients' informed consent and ethical clearance from the UNTH. The samples were collected and processed according to standard laboratory procedures. Results: Of the total 465 sputum samples, 366 (78.7%) were positive for micro-organisms. Four main types of bacteria have been identified: acinetobacter spp. 25.6%, Klebsiellla pneumoniae 25.6%, P. saeroginosa (1.39%), Candida (9.03%). The distribution of lower respiratory tract infections within the hospital department indicated that the isolated strains revealed a higher infection rate of Gram-negative bacteria in the Pediatric Intensive Care Unit (PICU) and General Surgical Intensive Care Unit (GSICU) compared to other departments, with statistical significance. Notably, there was a significant difference in the infection rates of Pseudomonas in the Special Care Baby Unit (SCBU) with 7 cases, and in the Medical Intensive Care Unit (MICU) with 6 cases, as well as in the Neonatal Intensive Care Unit (NICU) with 2 cases. The infection rates for Candida and Streptococcus pneumoniae in the NICU were recorded at 2, 1, and 2, respectively, which were significantly different from those observed in other departments. The prevalence of antimicrobial resistance among Gram-negative and Gram-positive bacterial isolates indicated a very high resistance rate (98–100%) among Acinetobacter baumannii isolates to various antibiotics including AK, AMC, ATM, CAZ, CRO, CIP, GN, MEM, TOB, PRL, and CZ. However, for SXT, the isolate demonstrated the highest sensitivity, with a resistance rate of less than 53%. Conclusion: Understanding the variety of pathogens that cause lower respiratory tract infections (LRTIs) and their patterns of susceptibility to antibiotics, in addition to monitoring antibiotic resistance, is crucial for the effective management of LRTIs. This includes timely clinical and laboratory diagnoses, as well as the implementation of the appropriate treatment strategies.

Comorbidity of problematic substance use and other addictive behaviors and anxiety, depression, and post-traumatic stress disorder: a network analysis.

Among those with common mental health disorders (e.g. mood, anxiety, and stress disorders), comorbidity of substance and other addictive disorders is prevalent. To simplify the seemingly complex relationships underlying such comorbidity, methods that include multiple measures to distill which specific addictions are uniquely associated with specific mental health disorders rather than due to the co-occurrence of other related addictions or mental health disorders can be used. In a general population sample of Jewish adults in Israel (N = 4002), network analysis methods were used to create partial correlation networks of continuous measures of problematic substance (non-medical use of alcohol, tobacco, cannabis, and prescription sedatives, stimulants, and opioid painkillers) and behavioral (gambling, electronic gaming, sexual behavior, pornography, internet, social media, and smartphone) addictions and common mental health problems (depression, anxiety, and post-traumatic stress disorder [PTSD]), adjusted for all variables in the model. Strongest associations were observed within these clusters: (1) PTSD, anxiety, and depression; (2) problematic substance use and gambling; (3) technology-based addictive behaviors; and (4) problematic sexual behavior and pornography. In terms of comorbidity, the strongest unique associations were observed for PTSD and problematic technology-based behaviors (social media, smartphone), and sedatives and stimulants use; depression and problematic technology-based behaviors (gaming, internet) and sedatives and cannabis use; and anxiety and problematic smartphone use. Network analysis isolated unique relationships underlying the observed comorbidity between common mental health problems and addictions, such as associations between mental health problems and technology-based behaviors, which is informative for more focused interventions.

Study of Prevalence of Premenstrual Dysphoric Disorder in Nursing Students

Background: Premenstrual dysphoric disorder (PMDD) is a common yet underdiagnosed mental health problem among women of reproductive age group with a significant potential to perturb social, academic, occupational, and interpersonal milieu of suffering women. The aim of this study is to see the Prevalence of PMDD in Nursing Students. Methods: A cross-sectional questionnaire-based study was conducted among the nursing students of the Acharya Shri Chander College of Medical Sciences Nursing School, Jammu and they were screened for the presence of PMDD using the Premenstrual Symptoms Screening Tool. Results: Prevalence of moderate to severe Premenstrual Syndrome (PMS) was 28.1% and PMDD was 6.1%. The commonest premenstrual symptom among the cases was fatigue or lack of energy. In the moderate to severe PMS category, it was anger, and in the PMDD category, it was anxiety. Impairment of college efficiency, or productivity was in 81.3% and 100.0% of students having moderate to severe PMS and PMDD, respectively. Conclusion: PMS and PMDD were prevalent among a substantial proportion of nursing students with significant negative influence on academic performance, emotional well-being and behavior. Strategies should be adopted in college health programs for the timely recognition and management of PMS and PMDD in nursing students.

The application of honey in treating wounds

Wounds such as burns, ulcers, and postoperative wounds always have a place on the list of common health problems in most countries. The inadequate treatment of these wounds seriously affects normal production, life, and economic development. Honey is not only a nutritious food, but also very useful in treating wounds. Honey has good antibacterial, anti-inflammatory, debridement, and anti-scab effects, and is also beneficial for tissue regeneration. These functions benefit from both its chemical composition and physical properties. This research mainly discusses the influence of honey varieties and honey usage methods on treatment effectiveness, the impact of honey treatment on different wounds, and the ability of honey to lighten scars. In terms of wound treatment, the main products related to honey include medical grade honey used directly, hydrogel added with honey, fiber membrane and ointment. Improved products such as hydrogel have improved the inconvenience of directly smearing honey to a certain extent. Honey has shown good effects in the treatment of burns, postoperative wounds, diabetes feet and other diseases, but there is still not enough research to clearly show how effective honey is in eliminating scars.

Boron-Doped Nano Hydroxyapatite Grafts for Bone Regeneration in Rat Mandibular Defects.

The aim of this study was to evaluate the potential effects of boron-doped nano hydroxyapatite grafts on craniofacial bone regeneration in critical bone defects in the mandibular corpus of rats, in terms of scintigraphic and histopathological aspects. Forty Wistar albino rats, with an average weight of 200-220g, aged 16-18weeks, and all male, were used in the study. The rats were randomly assigned to five groups, each containing 8 rats, as follows: group C1 (no procedure applied to the mandible), group C2 (surgical defect created in the mandible but no treatment applied), group nHA (nano hydroxyapatite applied to the surgical defect area), group nHA + B1 (nano hydroxyapatite + 1% boron applied to the surgical defect area), and group nHA + B2 (nano hydroxyapatite + 2% boron applied to the surgical defect area). A standard 4 × 4mm full-thickness transosseous bone defect was created in the mandibular corpus of all rats, except for those in group C1. The bone defect in the rats in group C2 was left to heal naturally. Nano hydroxyapatite (nHA), nano hydroxyapatite + 1% boron, and nano hydroxyapatite + 2% boron were applied to the surgical defect areas of the other three groups, respectively. Bone scintigraphy was performed on all rats on days 0 (following the surgical procedure) and 28 of the experimental period. At the end of the 28th day, the animals were sacrificed, and tissue samples were collected for histological examination. A standard grading system was used to evaluate fracture healing. When the groups were compared in terms of bone healing histopathological scores, a statistically significant difference was observed between group C1 and the other groups (p < 0.005). In the statistical evaluation made according to the histopathological mean scores, the least improvement was observed in group C2. No statistically significant difference was observed between group nHA and group nHA + B1 and group C2 and between group nHA and group nHA + B1 in terms of bone healing scores (p > 0.005). A statistically significant difference was found between group nHA + B2 and group C2 (p = 0.026). Although there was no statistically significant difference in histopathological scores, the mean score closest to group C1 was observed in group nHA + B2. A statistically significant difference was observed between the groups in the scintigraphic evaluation performed on the 28th day of the experimental procedure, and the difference was between group C1 and group nHA + B1 and between group nHA and group nHA + B1 (p = 0.004; p = 0.028, p < 0.005). In the comparison of the values obtained on days 0 and 28 within the group, a statistically significant change was observed in group nHA + B1 and group nHA + B2 (p < 0.005). When the results of the present study were evaluated, it was thought that the boron-doped nHA graft biomaterials may have positive effects on bone healing. Providing a different perspective for the development of an alternative new treatment modality that can be locally applied in the treatment of fractures a serious and common health problem can be interpreted as an important outcome of the present study. We believe that this study will serve as a preliminary study for more comprehensive future studies on this subject.

Health problems among disaster responders to the 2023 Turkey-Syria earthquake: a cross-sectional study

ObjectiveThe aim of this study was to describe perceived health problems among disaster responders after the earthquake in eastern Turkey/Syria in February 2023.MethodsA non-probability cross-sectional study was conducted using an online survey.ResultsA total of 525 local (18%) and international disaster responders (81%) participated in the study. Of these responders, 46% reported physical or mental health problems during or after their deployment, 15% required medical care during the mission, and 7% required medical evacuation. The most common health problems during the field mission were feeling scared or unsafe, sleeping problems, and headache. After the mission, fatigue, sleeping problems, and feeling depressed were the most frequently reported health problems. The local responders perceived significantly more health problems than did the international responders. Approximately 11% of the participants could not return to their ordinary work after deployment because of infections or mental health issues.ConclusionsPhysical and mental health problems are commonly perceived by disaster responders and may reduce the effectiveness of disaster response. Raising awareness of health risks among disaster response workers and employers is essential to ensure proper duty of care and should include reparations and medical support during and after disaster response operations.

The Mental Health of Sexual Minority Individuals: Five Explanatory Theories and Their Implications for Intervention and Future Research

Research on the disparity in common mental health problems borne by sexual minority individuals has entered a stage of increasing theoretical complexity. Indeed, such a substantial disparity is likely not determined by a singular cause and therefore warrants diverse etiological perspectives tested with increasingly rigorous methodologies. The research landscape is made even more complex by the constant and rapid shift in the ways in which sexual minority people understand and characterize their own identities and experiences. This review introduces readers to this complexity by summarizing the historical legacy of research on the sexual orientation disparity in mental health, describing five contemporary theoretical explanations for this disparity and their supporting evidence, and suggesting theoretically informed interventions for reducing this disparity. Last, we offer an agenda for future research to accurately model the complexity of the pathways and solutions to the disproportionately poorer mental health of sexual minority populations.

Early mental health intervention and supported self-care for LGBTQ+ young people in the UK: a mixed-methods study.

Lesbian, gay, bisexual, trans, queer/questioning, plus young people have a higher risk of poor mental health in comparison to cisgendered heterosexual young people, and they underutilise mental health services and support. In addition, there is a paucity of research conducted in United Kingdom examining mental health early intervention provision for lesbian, gay, bisexual, trans, queer/questioning, plus young people. To produce a model of what works for early intervention mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus young people and increase understanding of lesbian, gay, bisexual, trans, queer/questioning, plus young people's access to, navigation of, and engagement with mental health support. This was a multi-methods theory-led case study evaluation with three distinct stages: (1) a meta-narrative review of existing literature to develop a theoretical framework to explain effective mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus young people; (2) an online and offline service mapping exercise to locate current mental health early intervention support for lesbian, gay, bisexual, trans, queer/questioning, plus young people in the United Kingdom in order to produce a service typology; and (3) a theory-led case study evaluation of 12 case study sites selected from the service typology produced in stage 2, to establish the components of appropriate quality, early intervention mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus young people. Stage 1 produced an interdisciplinary theoretical framework indicating that early intervention mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus youth must prioritise addressing normative environments that marginalise youth, lesbian, gay, bisexual, trans, queer/questioning, plus identities and mental health problems. Stage 2 mapping found 111 services, the majority in urban settings in England. There was an absence of mainstream National Health Service support that specifically addressed the needs of lesbian, gay, bisexual, trans, queer/questioning, plus young people. The majority of lesbian, gay, bisexual, trans, queer/questioning, plus youth mental health support was provided by voluntary/community organisations. Stage 3 case study evaluation found that an intersectional, youth-rights approach is the most appropriate way to deliver early intervention mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus young people. Youth rights should underpin mental health support to address the multiple marginalisation, isolation and stigmatisation that lesbian, gay, bisexual, trans, queer/questioning, plus young people may experience and to enable them to make informed independent decisions about their own bodies and lives, and for the right to freedom of safe self-expression to be upheld. The model that we have produced contains 13 principles that are necessary to the provision of mental health support, and to improve access to, engagement with, and navigation of mental health services. In the United Kingdom, a rights-based approach to mental health service provision is not prominent. In addition, at the time of writing, lesbian, gay, bisexual, trans, queer/questioning, plus young people are facing active legislative and policy attacks on their human rights. This study provides the first large-scale theory-led evaluation of early intervention mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus young people with common mental health problems. The resulting intersectional, youth-rights approach provides evidence on ways of improving lesbian, gay, bisexual, trans, queer/questioning, plus young people's mental health. Further research on the implementation of an intersectional, youth-rights approach to early intervention mental health support for lesbian, gay, bisexual, trans, queer/questioning, plus young people with mental health problems is required. This study is registered as PROSPERO CRD42019135722. This award was funded by the National Institute for Health and Care Research (NIHR) Health and Social Care Delivery Research programme (NIHR award ref: 17/09/04) and is published in full in Health and Social Care Delivery Research; Vol. 12, No. 47. See the NIHR Funding and Awards website for further award information.

ASUHAN KEPERAWATAN JIWA GANGGUAN PERSEPSI SENSORI PENDENGARAN DENGAN PERILAKU CARING PERAWAT BERDASARKAN TEORI JEAN WATSON

Hallucinations are one of the most common mental health problems experienced by those with mentaldisorders. The purpose of this case study is to describe the implementation of mental health nursing care for sensory perception disorders of hearing with nurse caring behavior based on Jean Watson's theory. The number of clients used is 3 people, namely clients who experience sensory perception disorders in Srigonjo village. The design of this case study is descriptive qualitative using interview techniques, observation, direct observation, and data collection using patient assessments. The nursing problem raised is sensory perception disorders of hearing. and the nursing actions given are hallucination management. Before being given the action, it was found that the three patients often heard whispering voices inviting them to talk, liked to talk to themselves, daydreamed, liked to smile to themselves, mumbled, often looked at the outside environment or did not concentrate, were uncooperative and the patients looked dirty. After the intervention was given, the patient experienced changes where eye contact was already there when spoken to, was able to concentrate, and was able to apply the rebuke techniques taught. Thus, it can be said that hallucination management with Jean Watson's theoretical approach has a good impact.

Metabolic syndrome in association with novel dietary index, metabolic parameters, nesfatin-1 and omentin-1

BackgroundMetabolic syndrome is a prevalent and common health problem and numerous studies have revealed the role of diet and lifestyle change in prevention of metabolic syndrome. However, the novel dietary index, cardioprotective index (CPI) and its association with metabolic syndrome is not investigated yet. In the current study, we evaluated the association between metabolic syndrome and its components, CPI, Nesfatin-1 and Omentin-1in a cross-sectional study.MethodsThree hundred forty eight overweight and obese individuals with metabolic syndrome were recruited. Subjects underwent anthropometric and laboratory assays including metabolic markers, Nesfatin-1 and Omentin-1 with commercial kits.ResultsThose at the first tertile of CPI had lower high density lipoprotein concentrations (HDL) and higher low density lipoprotein concentrations (LDL), triglyceride (TG), systolic and diastolic blood pressures (SBP, DBP) levels compared with those at the highest tertiles (P < 0.05). After adjustment for the confounding effects of age, sex, body mass index, physical activity and total calorie intake, LDL lost its significance across CPI tertiles. Moreover, serum total cholesterol, insulin and insulin resistance were not significant across CPI tertiles neither in crude nor in adjusted models (P > 0.05). Additionally, being at the third tertile of CPI was accompanied with significantly higher Nesfatin-1 and Omentin-1 levels compared with lowest tertiels (P < 0.05) in crude and confounder – adjusted models. Conclusions: To our findings, CPI was in positive relationship with metabolic parameters, blood pressure, Nesfatin-1 and Omentin-1 levels in metabolic syndrome. Further future studies will help to elaborate the causality.Clinical trial numberNot applicable.

Associations between body mass index and physical fitness indicators among Chinese university students: a multicenter cross-sectional study

BackgroundIncreasing body mass index (BMI) has many negative effects on the physical and mental health of university students and has become a common public health problem in all countries. However, there are few studies on the association between BMI and physical fitness indicators among Chinese university students in developing countries, and the findings are inconsistent. The present study aims to analyze the association between BMI and physical fitness indicators among Chinese university students, to assist in university students’ health development and intervention.MethodsIn this study, we conducted a cross-sectional assessment of BMI of 29,371 university students and a cross-sectional assessment of physical fitness indicators of vital capacity, sit and reach, pull-up(boys), sit-up(girls), standing long jump, 50 m dash, 1000 m run(boys ), 800 m run(girls). One-way analysis of variance (ANOVA), Pearson’s correlation analysis, and nonlinear regression modeling were used to analyze the associations that existed between BMI and various physical fitness indicators.ResultsThe percentages of Chinese university students in emaciated, normal, overweight, and obese were 17.8%, 65.3%, 14.9%, and 2.0%, respectively. Comparing between different BMI groups (emaciated, normal, overweight, and obesity), for boys, the effect values ranged from 1.0 to 2.0% for the items of vital capacity, sit and reach, pull-up/situp, standing long jump, 50 m dash, and 1000/800 m-run. For run events, the range of effect sizes ranged from 0.2 to 0.9; the range of effect sizes for girls also ranged from 0.2 to 0.9.ConclusionsThe physical fitness level of emaciated and obese Chinese university students is generally lower than that of normal-weight students, and the relationship between BMI and physical fitness indicators shows a “U-shape” or “inverted U-shape” curve. The effect of BMI on physical fitness is more significant in boys than in university girls. In the future, targeted physical exercise and health education should be provided to emaciated and obese university students to maintain a reasonable body weight and promote the healthy development of physical fitness.

Breast size, thoracic kyphosis, and thoracic spine pain: a correlational survey of Nigerian postpartum mothers.

Thoracic spine postural dysfunctions are common postpartum-related health problems, compromising breastfeeding efficacy and quality of life among women. Previous studies have particularly associated these conditions with increased breast sizes in several populations. However, such empirical evidence is scarce in the Nigerian population. To investigate the relationship among breast size, thoracic-kyphosis, and -spine pain among postpartum Nigerian women. This correlational survey involved 400 consenting postpartum mothers (between 0 and 24 months of postpartum period). Their breast size, thoracic spine posture, and pain were measured using a measuring tape (cm), inclinometer, and Revised Oswestry thoracic spine pain disability questionnaire, respectively. Data were analyzed using descriptive and relevant inferential statistics at p < 0.05. The majority of the participants fall under the category of breast cup size B (61.75%), have no history of thoracic spine pain (87.4%), and about half of them (50.2%) have normal thoracic spine posture (low category with values ranging between 20⁰ and 35⁰. Breast size was significantly (r = 0.162, p = 0.001) correlated with thoracic spine posture but showed no significant correlation (r = 0.066, p = 0.622) with thoracic spine pain. Increasing breast size is weakly associated with a tendency towards a kyphotic posture of the thoracic spine. Postural education and care around adequate support of the breast with suitable fitting brassieres may help prevent kyphotic deformities. Future research with a randomized control trial and long-term follow-up is recommended to further confirm the causal relationship of these variables.

Artificial intelligence with counseling on the treatment outcomes and quality of life in periodontitis patients.

To evaluate the effects of artificial intelligence (AI)-assisted dental monitoring (DM) with and without health counseling on the treatment outcomes and oral health-related quality of life (OHRQoL) of patients with periodontitis. Patients with periodontitis were randomly assigned to either an AI group (AI group, n=28), an AI and health counseling group (AIHC group, n=27), or a control group (n=27). All patients underwent nonsurgical periodontal treatment. Patients in the AI and AIHC groups underwent additional AI-assisted DM and AI-assisted DM with oral health counseling, respectively, for 6 months. Data on OHRQoL and periodontal measures were collected at baseline and follow-ups. At 3 months of follow-up, the AI and AIHC groups exhibited a significantly greater reduction in probing pocket depth (mean diff: -0.5 and -0.7) and clinical attachment level (mean diff: -0.5 and -0.6) compared with the control group. At 6 months of follow-up, the AI and AIHC groups exhibited a significantly greater improvement in OHRQoL (mean diff: -4.5 and -4.7) compared with the control group. At 3-month follow-up, the AIHC group exhibited a greater improvement in plaque index (mean diff: -0.2) and OHRQoL (mean diff: -4.3) compared with the AI group. AI-assisted DM can be used to remind patients with periodontitis of their oral hygiene at home and effectively improve their periodontal measures and long-term OHRQoL. Gum disease is a common problem, but new technology could help. In this study, researchers looked at how AI affects gum health and quality of life (QoL). The researchers divided participants into 3 groups. One group used an AI system to monitor their gums at home. Another used AI plus got health advice. The third did not use any special technology. After 3 and 6 months, the AI groups had healthier gums, with less deep pockets and better gum attachment, compared to the group without AI. The group that also got health advice saw even greater improvements, like cleaner teeth and a bigger boost to their QoL. This is exciting because gum disease is tricky to manage alone. The AI system seems to help by reminding people to care for their teeth and gums. With expert guidance, the AI becomes an even more powerful tool for improving long-term oral health and well-being. This study shows how new technologies like AI could transform how we approach common health problems. By providing personalized support, AI can empower people to better manage their own health, leading to better outcomes.

Iron Deficiency Anemia: Etiology, Pathophysiology, Diagnosis, and Treatment Approaches

Iron deficiency anemia (IDA) is a common health problem that affects about 1.24 billion people around the world, mostly children and women of childbearing age. IDA happens when the body doesn't get enough iron, loses too much iron, or can't absorb it properly. This makes erythropoiesis, cellular metabolism, and immune function worse. The World Health Organization says that 40% of women who are pregnant and 32.5% of women who are not pregnant have anemia. People with IDA often feel tired, weak, pale, and have trouble thinking clearly. Lab tests, such as hemoglobin, blood ferritin, and transferrin saturation, are used to make the diagnosis. You can treat the condition in two ways: by taking iron supplements by mouth, such as ferrous sulfate, ferrous gluconate, and ferrous fumarate; or, for serious cases, by giving iron through an IV. Strategies for prevention depend on increasing the amount of iron you get from food, making it more bioavailable, and keeping infections under control. Food addition and fortification programs have been shown to help lower the number of people with IDA. However, problems still exist, especially in areas with poor economies. Recent advance in acknowledging how iron is used and controlled has implications for creating targeted therapeutic approaches. A key regulator of iron balance, hepcidin, is a key player in the pathophysiology of IDA. This review shows how complicated IDA is and how important it is to have treatment plans that consider underlying causes, dietary factors, and socioeconomic factors. Keywords: Iron Deficiency Anemia (IDA), Erythropoiesis, Hemoglobin, Nutritional Deficiencies, Neurological Disorders, Iron Supplements.

A Review on Psychological Factors of Eating Disorders

Abstract: Eating disorders (ED) are a common mental health problem that affect people all over the world and can have serious repercussions. It is essential to comprehend the psychological components of these disorders to effectively prevent and treat them. Finding the important factors can help develop individualised treatment plans, which will eventually lead to better mental health outcomes and the promotion of healthier eating habits. This study examines the psychological factors (PF) that influence ED and their effects on individual eating behavior and mental health. The article begins with an introduction to key psychological variables, including self-esteem (SE), perfectionism, anxiety, depression, and body image, emphasizing their importance in the development of ED. These psychological variables are categorized into emotional factors, cognitive factors, and behavioral factors, and the article analyzes how these elements affect individual eating habits and attitudes. Further empirical studies indicate that low SE and perfectionism are significantly correlated with ED, illustrating that women with low SE are more likely to develop unhealthy eating patterns. Additionally, anxiety and depression have notable effects on eating behavior, potentially leading to the onset of ED. Finally, the article outlines several treatment approaches for ED, including cognitive behavioral therapy, family therapy, and medication, discussing their effectiveness and limitations across different individual cases. Overall, a deeper understanding of these psychological variables will help develop more effective intervention strategies to support individuals with ED, promoting improved mental health and healthier eating behaviors.

Study of rotavirus genotypes G and P in one Egyptian center-cross-sectional study

BackgroundRotavirus-associated gastroenteritis is a common health problem in children, different variations of rotavirus genotypes differ according to geographic locations and the practice of wide-scale vaccination. Therefore, the present study aimed to detect both the G and P genotypes of rotavirus in children ≤ 5 years old in one center in Egypt as a cross-sectional study, to correlate the genotypes with various demographic and clinical data in infected children and to evaluate the common mixed genotypes G and P in infected children.MethodThe cross-sectional study included children with acute gastroenteritis ≤ 5 years old from January 2023 till March 2024 recruited from Mansoura University Children’s Hospital, Egypt based upon laboratory diagnosis by exclusion of bacterial and protozoa pathogens. The stool samples were obtained from each child and subjected to detection of rotavirus antigen by enzyme-linked immunosorbent assay (ELISA) followed by genotypes identification of G and P genotypes by nested polymerase chain reaction (PCR).ResultA nested PCR study for rotavirus genotypes revealed that G1 was the most common genotype (24.7%) followed by G2 (21.1%), G3 (20%), G9 (20%), and G4 (14.1%). The genotyping of the P genotype revealed that P9 was the commonest genotype (24.7%), followed by P4 (21.2%), P10 (20%), P8 (17.6%) and P6 (16.5%). The commonest combined genotypes of G and P were G1P4 (85.7%), G3P8(88.2%), followed by G2P6 (77.8%) and G9P9(76.5%) and G4P9 (66.7%) followed by G4P10 (33.3%), G9P10(23.5%), G2P10(22.2%), G1P10 (14.3%), G3P10(11.8%). The distribution was significant (P = 0.001). The positive rotavirus antigen was more frequently detected in females (55.3%) than males (44.7%, Odd ratio 0.2, 95% CI 0.22–0.71, P = 0.001). There was a significant association between the summer season and positive rotavirus antigen (P = 0.001) and rural residence of the patients (Odd ratio 6,9 95%CI 3,5-13.5, P = 0.001). The significant associated clinical sign with positive rotavirus antigen was fever (Odd ratio 3,3, 95%CI 1,8-6.05, P = 0.001). The genotypes G and P were significantly associated with positive rotavirus antigen as all cases positive by antigen had been detected by nested PCR with the commonest genotypes G4 (24.7%, P = 0.001) and genotype P9 (24.7%, P = 0.001).ConclusionThe present study highlights the common genotypes of rotavirus at one center in Egypt, G1, G2, and G3 were the commonest G genotypes. As regard genotype P the commonest genotypes were P9, P4, and P10. The commonest combined genotypes were G1P4, G3P8, G2P6. There was no effect of the practice of rotavirus vaccination at limited rates at private health sections as the rotavirus is still a major pathogen of acute gastroenteritis in children. There is a need for the inclusion of rotavirus vaccination in the national program of children vaccination in Egypt.

Pathogenesis of comorbidity between pulmonary tuberculosis and lung cancer

Pulmonary tuberculosis and lung cancer are both common clinical diseases and serious public health problems. These two diseases can form a comorbidity by promoting each other under the influence of multiple factors during their occurrence and development. In recent years, some progress has been made in understanding the mechanism and exploring the diagnosis and treatment of comorbidity. However, there are still some unclear mechanisms that require further investigation. This paper briefly introduces the epidemiological characteristics of the comorbidity between pulmonary tuberculosis and lung cancer, and focuses on the potential pathogenesis of the comorbidity. It highlights the current challenges and looks ahead to potential future research directions, including suggestions for the development of new diagnostic and therapeutic strategies for the comorbidity.

Family therapy and systemic interventions for child‐focussed problems: The evidence base

AbstractThis 25th anniversary review updates previous similar papers published in JFT in 2000, 2009, 2014 and 2019. It presents evidence from meta‐analyses and systematic reviews for the effectiveness of systemic interventions for families of young people with common mental and physical health problems and other difficulties where children are the primary focus of concern. In this context, systemic interventions include both family therapy and other family‐based approaches such as parent training, or parent‐implemented interventions. There is now a substantial evidence base supporting the effectiveness of systemic interventions either alone or as part of multimodal programmes for infant mental health and sleep and feeding problems in infancy; recovery from child abuse and neglect; externalising and internalising problems; eating disorders; somatic problems; and psychosis.

EVALUATION OF CUTANEOUS ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL IN SOUTHERN INDIA: A RETROSPECTIVE ANALYSIS

Objective: This study was undertaken to understand the demographic profile, common causative drugs, and the presentations of cutaneous adverse drug reactions (CADR) among the patients of our hospital. Methods: This is a retrospective analytical study. All CADR reported to our adverse drug reaction monitoring center from dermatology outpatient department (OPD), other OPDs, intensive care units, and inpatient wards of our hospital from September 2022 to March 2024 was collected from VIGIFLOW (software used by the pharmacovigilance program of India). The data was then analyzed. Results: A total of 272 CADR were reported over the study period. The median age of presentation was 41 years (Interquartile range=23). Overall 44 (16.18%) serious and 228 (83.82%) non-serious CADR were reported. Erythematous maculopapular rash was the most common clinical presentation (63%). Bullous exfoliative drug eruptions and Stevens Johnson’s syndrome were some of the serious CADR. The most common suspected medications were antibiotics (42.15%) followed by non-steroidal anti-inflammatory drugs (8.92%). In 76% of the cases, the suspected medication was withdrawn. The outcome was reported as “Recovering” in 52% of the cases. On causality assessment, 251 (92%) CADR were classified as “Possible.” Conclusion: A CADR is a common yet preventable health problem. As seen from our study, most of the suspected medications were withdrawn and subsequently the patients were recovering from the CADR. Hence, early diagnosis, identification, and withdrawal of the implicating drugs help in timely recovery and prevention of complications, which in turn help in decreasing the burden on our healthcare system.