Common Femoral Artery Doppler Research Articles

Common femoral artery doppler findings pre and post hyperbaric oxygen therapy for leg ulceration

Hyperbaric Oxygen Therapy (HBOT) assumes that high pressure hyperoxygenation causes faster tissue recovery and wound healing. Lower extremity flow rates are affected by leg ulcers that change vasodilation, microcirculation resistance, and local tissue demands; how blood hyper oxygenation influences these factors is still unclear. Peripheral arterial occlusive disease (PAOD) has been mostly associated with HBOT results in the femoral artery than in other arteries. Common femoral artery (CFA) peak systolic velocities (PSV), measured pre and post HBOT, were analyzed to research HBOT hemodynamics. Sixteen patients with leg ulcers who were 65 ± 11 (SD) (38-87) years-old, had HBOT of 90 minutes at 2.6 ATA. Bilateral CFA Doppler velocity waveforms were recorded immediately pre and post HBOT. Ulcerated vs non-ulcerated peak systolic velocity (PSV) data were compared using paired t-test. CFA PSV were significantly equal in the ulcerated and non-ulcerated extremities before HBOT: 114 ± 35 (SD) cm/s vs 116 ± 41 cm/s (p = 0.87 by paired t-test). CFA PSV in the ulcerated extremity increased to 122 ± 35 cm/s after HBOT but were statistically insignificant (p =.19 by one-tailed paired t-test). On the other hand, CFA PSV decreased to 103 ± 28 cm/s (p =.049 by one-tailed paired t-test) in the non-ulcerated extremity and were significantly lower after HBOT, with 103 ± 28 cm/s vs 122 ± 35 cm/s for the ulcerated limb (p =.02 by paired t-test). Blood velocity responses post HBOT showed differences between ulcerated vs non-ulcerated extremities. The non-ulcerated extremity apparently responded to oxygenation more than the ulcerated extremity. Such observation suggests further research on hemodynamic reactions caused by HBOT.

Accuracy of Common Femoral Artery Doppler Waveform Analysis in Predicting Haemodynamically Significant Aortoiliac Lesions.

Doppler ultrasound is cost-effective and accurate noninvasive method for evaluation of peripheral arterial disease. However, there is difficulty in detection of aortoiliac lesions due to inadequate visualization of aortoiliac arteries in many patients. The Doppler waveform changes occurring distal to significant stenosis or occlusion are well documented. Accordingly, common femoral artery (CFA) Doppler waveform analysis may be used to predict haemodynamically significant proximal aortoiliac lesions. To evaluate the accuracy of Doppler waveform analysis at the CFA for diagnosing haemodynamically significant aortoiliac stenosis or occlusion in patients of peripheral arterial disease. A total of 67 patients (114 aortoiliac segments) with suspected peripheral arterial disease were retrospectively evaluated and labeled as normal or abnormal by analysing the Doppler waveform of CFA. The triphasic waveform with normal reversal pattern was categorized as normal, while low velocity biphasic or monophasic waveform were labeled as abnormal and indirect diagnosis of normal or diseased (>50% stenosis or occlusion) aortoiliac segment was made. The results were compared to intra-arterial angiography, considered as the gold standard. The Doppler waveform analysis of CFA was abnormal in 41 out of 114 common femoral arteries, while intra-arterial angiography showed significant stenosis (21 arteries) or occlusion (26 arteries) in 47 (41%) of 114 aortoiliac segments in 67 patients. Out of 67 normal aortoiliac segments seen on angiography, the CFA waveform analysis was interpreted as normal in 62 segments. An abnormal CFA waveform could diagnose significant aortoiliac lesion with 87% sensitivity, 92% specificity, 89% Positive Predictive Value (PPV), 91% Negative Predictive Value (NPV) and 90% accuracy using angiography as the gold standard. The low velocity monophasic waveform which was seen in 38 (33%) of 114 segments was reliable predictor of significant aortoiliac disease with 93% positive predictive value. CFA Doppler waveform pattern analysis is a sensitive and accurate technique for the prediction of haemodynamically significant aortoiliac stenosis or occlusion.

Echocardiographic evaluation of aorto-iliac occlusive disease

Several studies demonstrated feasibility of visual assessment of the common femoral artery Doppler waveform, in an indirect evaluation of aorto-iliac segment stenosis. Patients with cardiac diseases referred for echocardiography often have coexistent arterial pathology. Since many of them are potential candidates for endovascular procedures, we decided to study, whether echocardiography can be useful for detection of aorto-iliac occlusive disease. We evaluated 92 patients with abdominal aortic aneurysm or peripheral artery occlusive disease, referred from the vascular surgery department for cardiac evaluation before surgery. At the end of an echocardiographic examination, evaluation of flow in the distal external iliac arteries with an echocardiographic probe was performed. The Doppler waveform was classified into normal—with early diastolic flow reversal or abnormal—without early diastolic flow reversal. Echocardiographic results were compared in a blinded fashion with reports from computed tomography angiography. Overall there were 58 iliac segments with significant (≥70%) area stenosis or occlusion and 126 iliac segments without significant disease on computed tomography angiography. Abnormal Doppler waveform was found in 56 out of 58 abnormal iliac segments—sensitivity 97%, and normal waveform was found in 106 out of 126 normal iliac segments—specificity 84%. Positive predictive value of abnormal Doppler waveform for significant iliac disease was 74%, and negative predicting value was 98%. Detection of significant stenoses in aorto-iliac segments is feasible with echocardiography. Further studies are necessary to evaluate its potential utility in a population of patients with cardiac disease referred for echocardiographic study.

1546: Abdominal Aortic Aneurysm Detection by Common Femoral Artery Doppler Ultrasound Waveform Analysis

1546: Abdominal Aortic Aneurysm Detection by Common Femoral Artery Doppler Ultrasound Waveform Analysis

Duplex Arteriography Prior to Femoral-Popliteal Reconstruction in Claudicants: A Proposal for a New Shortened Protocol

The standard preoperative duplex arteriography (DA) from the aorta to the pedal vessels is time consuming and may be unnecessary in patients presenting with calf claudication alone. The feasibility of a shortened protocol was evaluated. Of 286 femoral-popliteal reconstruction based on DA during the last 4A years, 79 (28%) were primary operations for calf claudication. Eliminating the aortoiliac portion of the test except for the distal external iliac artery and limiting the scanning of the infrapopliteal vessels to one or two arteries in the leg would significantly shorten the exam. To confirm the adequacy of the inflow tract, we relied on the common femoral artery Doppler waveform analysis and the intraoperative graft pressure upon completion of the bypass. Of the 79 primary femoral-popliteal bypasses, 53 (67%) had triphasic common femoral artery waveform and the remaining 26 had monophasic or biphasic waveforms. Three (6%) of the 53 femoral-popliteal bypasses in the former group had significant pressure gradients measured intraoperatively and were treated with iliac angioplasties and stents for unsuspected stenoses in 2 cases and a covered stent for a common iliac aneurysm in 1 case. Three, two, and one infrapopliteal vessel runoff was observed in 24 (45%), 16 (30%), and 9 (17%) extremities, respectively. Four patients (8%) had significant stenoses (>50%) or occlusion of all three infrapopliteal arteries. Eighty-one percent of the patients would have completed the short protocol had we scanned the peroneal artery initially. An additional 8% would have required scanning of a second vessel (anterior tibial) and only 11%, scanning of all three infrapopliteal vessels. The time interval for completion of short-protocol DA was significantly less than the time for the standard DA (16.2 A+/- 5.2A min vs. 35.1 A+/- 10.6 min) ( p < 0.01). We believe that the proposed short DA protocol combined with intraoperative graft pressure measurements can be used in 94% of the patients who have a patent popliteal artery (>/= 7 cm). It is a totally noninvasive approach that is particularly suitable for vascular technologists and surgeons who wish to start utilizing DA instead of contrast arteriography prior to infrainguinal reconstructions. However, the short protocol does not avert the need for completion arteriography of the inflow arteries and readiness to perform endovascular procedures to correct lesions not suspected by common femoral artery waveform analysis.

Screening for aortoiliac lesions by visual interpretation of the common femoral Doppler waveform.

to study the accuracy of simple visual interpretation of the common femoral artery Doppler waveform for screening the aorto-iliac segment for significant occlusive disease. prospective and semi-blinded study. Material ninety-four consecutive and elective patients having arteriography due to chronic lower limb ischaemia, presenting symptoms of severe claudication (23%), ischaemic rest pain (34%) or ischaemic skin lesions (43%). one day prior to conventional arteriography a Doppler waveform was obtained in the common femoral artery. Based on visual interpretation, the waveforms were immediately categorised as normal or abnormal. Comparison with single plane arteriography with respect to significant aorto-iliac occlusive disease was undertaken. visual Doppler waveform interpretation had a sensitivity of 98% (95% CI: 90-100%), a specificity of 81% (CI: 67-90%), a positive predictive value of 86% (CI: 75-93%) and a negative predictive value of 97% (CI: 86-100%) for prediction of significant aorto-iliac occlusive disease using conventional arteriography as the gold standard. The kappa value for the agreement between Doppler waveform interpretation and arteriography was 0.81 (0.68-0.93), representing very good agreement. a normal common femoral Doppler waveform can safely exclude significant upstream aorto-iliac lesions and is a useful timesaving screening tool in the busy vascular laboratory. The method is well tolerated, easy to perform and requires no additional equipment.

Artificial neural network analysis of common femoral artery Doppler shift signals: classification of proximal disease

The aim of this study was to apply artificial neural networks (ANNs) to the problem of the diagnosis of aorto-iliac arterial disease on the basis of the profile of the common femoral artery (CFA) Doppler flow velocity waveform. The maximum frequency envelopes obtained from the CFA of 180 subjects were used to create sets of training and testing vectors for a back-propagation ANN. The ANN had three outputs: one representing the absence of significant aorto-iliac disease ( i.e., < 50% diameter stenosis), one representing the presence of a hemodynamically significant aorto-iliac stenosis ( i.e., 50–99% stenosis), and the other representing the presence of an aorto-iliac occlusion. After training, the ANN correctly classified 80% of “no significant disease” testing data, 45% of “significant stenosis” data and 85% of “occlusion” data. This work, thus, demonstrated the ability of an ANN to identify the severity of aorto-iliac disease from the CFA waveform. Although the ANN outperformed standard univariate methods and visual classification of the data, it would appear that further work is needed to increase the accuracy of the ANN to a clinically acceptable standard.

Analysis of femoral artery Doppler signals by LaPlace transform damping method.

The LaPlace transform damping (LTD) method of common femoral artery Doppler waveform analysis is a new method for assessing aortoiliac stenosis. A microcomputer was used to analyze the waveform to determine the value of the damping parameter, which is related to inflow stenosis. The study included 60 limbs with arterial disease and 20 limbs in normal control subjects. With a damping value of 0.60 used as the cutoff point between nonocclusive lesions and iliac stenoses of greater than 50% diameter reduction, we found a sensitivity of 100% and a specificity of 93% (overall accuracy 95%). Unlike Doppler waveform analysis by the pulsatility index method, the accuracy of the LTD method is not affected by occlusion of the superficial femoral artery. The Doppler signal processor and the computer currently used for the LTD analysis are simple to operate and fully suitable for routine use in a clinical vascular laboratory. Our experience indicates that the LTD method of waveform analysis provides the best noninvasive method for detection of significant inflow disease.

Analysis of femoral artery Doppler signals by LaPlace transform damping method

The LaPlace transform damping (LTD) method of common femoral artery Doppler waveform analysis is a new method for assessing aortoiliac stenosis. A microcomputer was used to analyze the waveform to determine the value of the damping parameter, which is related to inflow stenosis. The study included 60 limbs with arterial disease and 20 limbs in normal control subjects. With a damping value of 0.60 used as the cutoff point between nonocclusive lesions and iliac stenoses of greater than 50% diameter reduction, we found a sensitivity of 100% and a specificity of 93% (overall accuracy 95%). Unlike Doppler waveform analysis by the pulsatility index method, the accuracy of the LTD method is not affected by occlusion of the superficial femoral artery. The Doppler signal processor and the computer currently used for the LTD analysis are simple to operate and fully suitable for routine use in a clinical vascular laboratory. Our experience indicates that the LTD method of waveform analysis provides the best noninvasive method for detection of significant inflow disease.