Abstract Submersible axial flow pump is capable of generating large flow rate at high efficiency and is widely used in agriculture, irrigation, water supply and drainage in factories, urban areas, etc. Pumps are always designed to operate at the designed conditions of flowrate and head, but in certain practical applications, their off- design operation seems to be more important, like if there is waterflooding due to heavy rainfall or in case of variable flowrate, variable head operations or long-distance water supply. These situations arise for limited operation (time) and hence it is not economical to change the existing pumping system. The present work deals with the analysis of submersible axial flow pump at design as well as off-design conditions. This off-design operation was controlled by the variable inlet guide vane (VIGV) with the task of making it energy efficient for all conditions. The scope of this work was to investigate the performance of selected pump at designed rotational speed, at designed flowrate (Q/Qd =1) as well as Q/Qd =0.8 and Q/Qd =1.2, using Computational Fluid Dynamics (CFD) and at various VIGV angles in the range of ±25°. The fluid flow analysis was performed using commercial CFD tool ANSYS CFX v17.0. From the numerical study, it was concluded that the performance of the considered AFP significantly increased due to the presence of VIGV at positive rotation angles. The best performance was observed for IGV angle of +25° for all flowrates. As compared to the reference case of 0° IGV rotation, the performance of the AFP increased by 28.42% in terms of head ratio and 0.235% in terms of hydraulic efficiency, for +25° IGV angle, at the designed flowrate. Also, an increment of 69.05% in terms of head ratio and 14.49% in terms of hydraulic efficiency was observed at overload condition of Q/Qd =1.2.