Background: Hirschsprung disease (HD) is a rare congenital anomaly (1 in 5000 live births) characterized by varying levels of aganglionosis. The evolution of surgical options and outcomes for the successful management of HD has been driven by the aspiration of pediatric surgeons. Hirschsprung's disease postoperative results of pull-through procedure could be influenced by surgical and pathological proficiency and the quality of perioperative care. Controversies persist as to which technique offers the best outcome. The absence of incontinence and constipation remains the most important marker of a good outcome. Methods: Medical records of HD children who underwent temporary colostomy procedures were analyzed retrospectively from July 2017 to June 2021. Risk factors were evaluated to determine the outcome of HD procedures. Results: Ninety-two HD patients were included. Based on the univariate analysis, most patients in the study (58.7%) were between the ages of 2 and 12 months. The study population predominantly consisted of males (68.5%) who had low vegetable intake (65.2%) and occasionally exhibited stool stains (66.3%), but their stool consistency was mainly normal (47.8%). Further examination through bivariate analysis revealed a significant negative correlation between stool stains and SOAVE (name of the condition). Similar findings were observed for stool consistency, indicating a significant correlation. Consequently, both variables were subjected to multivariate analysis. The multivariate analysis demonstrated a significant association between stool consistency and SOAVE among patients aged 2-12 months (p=0.000, OR =2.044E-7) and those aged 1-5 years (p=0.000, OR =2.044E-7). An odds ratio (OR) value of less than 1 implies that individuals with normal stool consistency have a lower likelihood of experiencing SOAVE at a young age. Conclusions: This study showed that children with HD correlated with low daily vegetable intake. Normal feces were associated with higher SOAVE ages and a lower possibility of experiencing SOAVE at a young age.
Read full abstract