In this article, full-scale experiments with a dynamic obstacle intention-aware Collision Avoidance System (CAS) are presented. The CAS consists of the Probabilistic Scenario-Based Model Predictive Control (PSB-MPC) for trajectory planning, dynamic obstacle avoidance, and antigrounding, with a Dynamic Bayesian Network (DBN) used for inferring obstacle intentions online. The novelty of this article lies in the utilization of intention information in deliberate collision-free planning. By inferring multiple different intention states on how and if nearby obstacles adhere to the COLREGS, the PSB-MPC can plan COLREGS-compliant avoidance maneuvers when possible, taking into account its awareness of the situation. The experiments put emphasis on hazardous situations where this intention information is both useful and necessary in order to avoid high collision risk. To the authors’ knowledge, the work is the first field experimental validation of such a probabilistic intention-aware CAS with consideration of multiple intention states. The experimental results demonstrate the validity of the proposed CAS scheme, with adherence to the traffic rules (COLREGS) 7, 8 and 13–17 in a diverse set of situations. The strengths and weaknesses of the proposed CAS are also discussed, giving insights that can be useful for researchers and practitioners in the field. Here, challenges related to detecting obstacle maneuvers and making the intention inference more robust to noise should be addressed as future work to make the scheme better suited for general usage on ships engaged in real traffic.