Cognitive Failures Research Articles

Long-term health outcomes of COVID-19 in ICU- and non-ICU-treated patients up to 2 years after hospitalization: a longitudinal cohort study (CO-FLOW)

BackgroundMany patients hospitalized for COVID-19 experience long-term health problems, but comprehensive longitudinal data up to 2 years remain limited. We aimed to (1) assess 2-year trajectories of health outcomes, including comparison between intensive care unit (ICU) treated and non-ICU-treated patients, and (2) identify risk factors for prominent health problems post-hospitalization for COVID-19.MethodsThe CO-FLOW multicenter prospective cohort study followed adults hospitalized for COVID-19 at 3, 6, 12, and 24 months post-discharge. Measurements included patient-reported outcomes (a.o., recovery, symptoms, fatigue, mental health, sleep quality, return to work, health-related quality of life [HRQoL]), and objective cognitive and physical tests. Additionally, routine follow-up data were collected.Results650 patients (median age 60.0 [IQR 53.0–67.0] years; 449/650 [69%] male) surviving hospitalization for COVID-19 were included, of whom 273/650 (42%) received ICU treatment. Overall, outcomes improved over time. Nonetheless, 73% (322/443) of patients had not completely recovered from COVID-19, with memory problems (274/443; 55%), concentration problems (259/443; 52%), and dyspnea (251/493; 51%) among most frequently reported symptoms at 2 years. Moreover, 61% (259/427) had poor sleep quality, 51% (222/433) fatigue, 23% (102/438) cognitive failures, and 30% (65/216) did not fully return to work. Objective outcome measures showed generally good physical recovery. Most outcomes were comparable between ICU- and non-ICU-treated patients at 2 years. However, ICU-treated patients tended to show slower recovery in neurocognitive symptoms, mental health outcomes, and resuming work than non-ICU-treated patients, while showing more improvements in physical outcomes. Particularly, female sex and/or pre-existing pulmonary disease were major risk factors for poorer outcomes.Conclusions73% (322/443) of patients had not completely recovered from COVID-19 by 2 years. Despite good physical recovery, long-term neurocognitive complaints, dyspnea, fatigue, and impaired sleep quality persisted. ICU-treated patients showed slower recovery in neurocognitive and mental health outcomes and resumption of work. Tailoring long-term COVID-19 aftercare to individual residual needs is essential. Follow-up is required to monitor further recovery.Trial registration: NL8710, registration date 12-06-2020.

The mediating role of sleep quality between pre-sleep portable media device use and nursing performance

The prevalence of portable media device (PMD) use has proliferated, potentially causing serious problems, particularly in critical situations. The main aim of the present study was to investigate the relationship between pre-sleep PMD use and cognitive performance, as well as the mediating effects of sleep quality among nurses. A cross-sectional study was designed, with 200 registered nurses voluntarily participating. The average time spent on PMDs was self-reported. The Pittsburgh Sleep Quality Index, the epworth sleepiness scale, the Occupational cognitive failures questionnaire, and the Nursing Errors Questionnaire were used to collect data. Correlation analyses and structural equation modeling were conducted. Significant relationships were found between pre-sleep PMD use and all variables of interest. Sleep quality was significantly related to daytime sleepiness and occupational cognitive failures, mediating the effect of pre-sleep PMD use on these two variables. Problematic use of PMDs at bedtime may be considered an unsafe act for healthcare workers. Healthcare providers should be aware of the potential risks induced by excessive PMD use. Creating a culture of proper smartphone use is crucial for overcoming these challenges.

Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation.

Mitochondrial disease is a group of rare conditions, with no approved treatment to date, except for Leber hereditary optic neuropathy. Therapeutic options to alleviate the symptoms of mitochondrial disease are urgently needed. Sonlicromanol is a promising candidate, as it positively alters the key metabolic and inflammatory pathways associated with mitochondrial disease. Sonlicromanol is a reductive and oxidative distress modulator, selectively inhibiting microsomal prostaglandin E1 synthase activity. This Phase 2b program, aiming at evaluating sonlicromanol in adults with m.3243A>G mutation and primary mitochondrial disease, consisted of a randomized controlled (RCT) study (dose-selection) followed by a 52-week open-label extension study (EXT, long-term tolerability, safety, and efficacy of sonlicromanol). Patients were randomized (1:1:1) to receive 100- or 50-mg sonlicromanol, or placebo twice daily (bid) for 28 days with ≥2-week wash-out period between treatments. Patients who completed the RCT study entered the EXT study wherein they received 100-mg sonlicromanol bid. Overall, 27 patients were randomized (24 RCT patients completed all periods). 15 patients entered the EXT, and 12 patients were included in the EXT analysis set. All patients reported good tolerability and favourable safety, with pharmacokinetic results comparable to the earlier Phase 2a study. The RCT primary endpoint (change from placebo in the attentional domain of cognition score [IDN: visual identification, Cogstate]) did not reach statistical significance. Using a categorisation of the subject's period baseline a treatment effect over placebo was observed if their baseline was more affected (p=0.0338). Using this approach, there were signals of improvements over placebo in at least one dose in the Beck Depression Inventory (BDI, p=0.0143), Cognitive Failure Questionnaire (CFQ, p=0.0113), and the Depression subscale of the Hospital Anxiety and Depression Scale (p=0.0256). Statistically and/or clinically meaningful improvements were observed in the patient- and clinician-reported outcome measures at the end of the EXT study (Test of attentional performance [TAP] with alarm, p=0.0102; TAP without alarm, p=0.0047; BDI somatic, p=0.0261; BDI Total, p=0.0563; SF12 physical component score, p=0.0008). Seven of nine domains of RAND-Short form-36 like SF-36 pain improved (p=0.0105). Other promising results were observed in Neuro QoL-Fatigue-SF (p=0.0036), MiniBESTest (p=0.0009), McGill Pain Questionnaire (p=0.0105), EQ-5D-5L-VAS (p=0.0213) and EQ-5D-5L-index (p=0.0173). Most patients showed improvement in the 5× sit-to-stand test. Sonlicromanol was well-tolerated and demonstrated a favourable benefit/risk ratio for up to one year. Sonlicromanol was efficacious in patients when affected at baseline, as seen across a variety of clinically relevant domains. Long-term treatment showed more pronounced changes from baseline.

Increased dementia risk in patients with Parkinson's disease attributed to metabolic syndrome.

Metabolic syndrome (MetS) manifests resembling pathophysiological mechanisms with Parkinson's disease (PD). Current research on the overall population has emphasized MetS as a freestanding risk factor for cognition. This research aims to explore the impact of MetS on cognition in Parkinson's patients. We involved subjects identified as having early-stage PD patients. The MetS was diagnosed dependent on parameters overviewed in the National Cholesterol Education Program's Adult Treatment Panel III. The clinical severity and stages in patients with PD were dependent on the disease rating scales. The cognition was evaluated by the Turkısh version of the Montreal Cognitive Assessment Scale (MoCA-TR). The cases were categorized according to cognitive failure: mild cognitive impairment in PD (PD-MCI), and PD dementia (PDD). Metabolic syndrome was present in 39.6% of the participants. 22.0% of patients were in the normal cognition, 29.1% in the PD-MCI group, and 48.9% in the PD-D group. The cognitive scores in patients with MetS is considerably lower than MetS negative group. A statistically notable inverse association was detected between fasting blood glucose levels and the visual-spatial/executive functions, naming, language, and orientation scores. The multivariate logistic regression analysis showed individuals with MetS were found to have an 11.308 times higher risk of PD-D (odds ratio [OR]: 11,3, 95% confidence interval [CI]: 1.61-79.2 ). We discerned the occurrence of MetS in PD raises the possibility of advancing dementia. This suggests that considering MetS in this patient group could contribute to the effective management of dementia.

Unveiling the impact of siren noise exposure on cognitive function and mental health among firefighters

Firefighters reside in inherently noisy environments with sirens and emergency alarms. This noise can negatively affect the performance of firefighters and further pose a safety risk. This study investigates the relationship between siren noise exposure and its mental health disorders. In doing so, the study focuses on cognitive function among firefighters, using a Bayesian network model for the first time. This case-control study involved 92 firefighters and was conducted in 2023. Participants were categorized into case and control groups based on their exposure levels to siren noise. Noise exposures were initially measured according to ISO 9612 standards. The questionnaires covered demographic information, scales of their depression, anxiety, and stress, the Buss-Perry aggression questionnaire, and the cognitive failure questionnaire. GeNIe academic software version 2.3 was employed for Bayesian network analysis. The study results indicated a strong association that heightened siren noise exposure with a 100% probability increases depression (10%), stress (14%), anxiety (13%), and aggression (16%). In addition, each variable–noise exposure, depression, stress, anxiety, and aggression was linked to cognitive failure by 8%, 28%, 8%, and 13%, respectively. The combination of variables including noise exposure, depression, anxiety, and other mental health disorders had a 57% increase in cognitive failure. The most influence values were observed between depression and cognitive failures (0.564). The results of this study demonstrated the effect of siren noise exposure and its mental health disorders on cognitive function among firefighters. The results further highlight proper implementation of measures to mitigate these effects, and further required investigation on their effectiveness.

Analyzing Protection Motivation Theory and Cognitive Failures in Texting While Driving Behavior Among Young Drivers

ABSTRACTTexting while driving (TWD) poses a significant hazard, particularly among young adults, as it requires simultaneous engagement in competing tasks. Despite widespread awareness of its dangers, drivers continue to engage in TWD. This study investigates the psychological and cognitive factors that influence TWD, employing the protection motivation theory (PMT). Structural equation modeling was conducted on a sample of 674 survey respondents aged 18–25. Factors influencing TWD behavior were revealed, including response cost, threat vulnerability, cognitive failure, self‐efficacy, and threat severity. Response cost was the primary barrier. Notably, not all subdimensions of threat appraisal and coping appraisal have a direct impact on TWD; cognitive failures serve as a mediator solely between threat vulnerability and response cost. An understanding of TWD provides insights into the TWD behavior of young drivers. By integrating the PMT with cognitive failure, this approach informs the development of interventions and regulations aimed at discouraging TWD and improving road safety.

Associations between taxi drivers' aggressive driving behavior and sleep, cognition, and psychological factors in Korea: negative binomial regression analysis.

Aggressive driving behavior is a significant predictor of traffic accidents. In particular, the driving behavior of taxi drivers is a critical issue that can impact the safety of both drivers and passengers. This study explored the sleep, cognitive, and psychological factors associated with taxi drivers' aggressive driving behavior. In this descriptive study, a self-report questionnaire was distributed to taxi drivers in Seoul and Gyeonggi Province from August 22, 2022 to December 30, 2022. In all, 992 respondents were analyzed using negative binomial regression. The mean score for aggressive driving behavior among taxi drivers was 13.76±11.47, with sub-scores of 3.46±3.48 for lapse, 3.31±3.16 for error, and 6.99±5.76 for violation. Contributing factors included sleep disorders, cognitive decline, and psychological factors. A higher score for aggressive driving behavior was associated with an increased severity of insomnia and daytime sleepiness, higher rates of cognitive failure, and elevated levels of depression and stress. Our findings highlight the importance of addressing the sleep, cognitive, and psychological factors associated with aggressive driving behaviors among taxi drivers. Further study is needed to evaluate the causal relationship. In addition, it is imperative to develop educational programs and interventions to manage these issues effectively.

Relationship between subjective cognitive functioning and fluid and crystallized cognitive abilities in bipolar disorder.

People with bipolar disorder (BD) often show inaccurate subjective ratings of their objective cognitive function. However, it is unclear what information individuals use to formulate their subjective ratings. This study evaluated whether people with BD are likely using information about their crystallized cognitive abilities (which involve an accumulated store of verbal knowledge and skills and are typically preserved in BD) or their fluid cognitive abilities (which involve the capacity for new learning and information processing in novel situations and are typically impaired in BD) to formulate their subjective cognitive ratings. Eighty participants diagnosed with BD and 55 control volunteers were administered cognitive tests assessing crystallized and fluid cognitive abilities. Subjective cognitive functioning was assessed with the Cognitive Failures Questionnaire (CFQ), daily functioning was rated using the Multidimensional Scale of Independent Functioning (MSIF) and the Global Assessment of Functioning Scale (GAF), and quality of life was assessed with the Quality of Life in Bipolar Disorder scale (QoL.BD). The BD group exhibited considerably elevated subjective cognitive complaints relative to controls. Among participants with BD, CFQ scores were associated with fluid cognitive abilities including measures of memory and executive function, but not to crystallized abilities. After controlling for objective cognition and depression, higher cognitive complaints predicted poorer psychosocial outcomes. Cognitive self-reports in BD may represent a metacognitive difficulty whereby cognitive self-appraisals are distorted by a person's focus on their cognitive weaknesses rather than strengths. Moreover, negative cognitive self-assessments are associated with poorer daily functioning and diminished quality of life.

Relationship of subjective and objective cognition with post-stroke mood differs between early and long-term stroke

Objective: Depression and anxiety affects approximately 1 in 3 stroke survivors. Performance on standardized objective cognitive tests and self-reported subjective cognitive symptoms are associated with concurrent depression and anxiety, but longitudinal data on whether and how objective and subjective cognition relate to emotional outcomes are lacking. Method: N = 99 stroke survivors (M age = 68.9, SD = 13.1; Median NIH Stroke Severity = 5) completed measures of depression and anxiety (Hospital Anxiety and Depression Scale; HADS), objective cognition (Oxford Cognitive Screen) and subjective cognitive symptoms (Cognitive Failures Questionnaire) at 6-months, 4.5, and 5.5 years post-stroke. The contribution of objective and subjective cognition to depression and anxiety was determined via mixed-effects models. Results: We found no evidence that age, stroke severity, years of education, and participant sex related to changes in HADS-Depression or HADS-Anxiety scores (Marginal R 2=0.03 and 0.05, respectively). Objective cognitive impairments at 6-months and increases in subjective cognitive symptoms at 5.5 years significantly related to increased HADS-Depression scores (Marginal R 2=0.22). Only increases in subjective cognitive symptoms at 5.5 years significantly related to increased HADS-Anxiety scores (Marginal R 2=0.20). When conducting models in reverse, HADS-Depression and HADS-Anxiety scores did not reciprocally explain changes in subjective cognitive symptoms. Conclusions: Objective cognitive abilities are more strongly associated with depression at 6-months post-stroke, while subjective cognitive symptoms are more relevant to both long-term post-stroke depression and anxiety. There may be a unique unidirectional influence of subjective cognitive symptoms to post-stroke depression and anxiety.

Understanding delusions to improve our mutual interactions: A précis of <i>"Why Delusions Matter"</i>

Why Delusions Matter is a reflection on the importance of the study of delusions for better understanding and reshaping our mutual interactions. The study of delusions has transformed the philosophy of mind and psychology in the last thirty years, helping redefine the relationship between rationality and intentionality. It has still a lot to offer to emerging areas at the intersection of ethics and epistemology. These are areas where the focus of the investigation of beliefs is moving from a painstaking assessment of the individual’s cognitive achievements and failures to a broader examination of the environmental and social pressures on the adoption, revisions, and maintenance of beliefs at individual and collective levels. In the book, there is an exploration of the notion of delusionality across clinical and non-clinical contexts which shows how delusions are meaningful beliefs that matter to the speaker's identity but are received by the interpreter as implausible and unshakeable. Delusions are not pathological by default, but they can bring epistemic and psychological costs as well as temporary benefits. Although a speaker's delusions can make collaboration difficult, this should not discourage interpreters from attempts at genuine engagement. Delusions are not a sign of a breakdown in the speaker's capacity for agency and thus understanding them can help interpreters appreciate the speaker's perspective.

Perceived cognitive loss, symptomology, and psychological well-being with bipolar disorder

BackgroundAdults with bipolar disorder (BD) commonly present with cognitive deficits. Many also report subjective or perceived cognitive failures. For this study, we identified four distinct clusters of adults with BD on the basis of both BD symptoms (depression and hypo/mania) and perceived cognitive errors (i.e., forgetfulness, distractibility, false triggering). We hypothesized that participants reporting more BD symptoms and cognitive errors would report lower psychological well-being (i.e., self-efficacy, life scheme, life satisfaction). A second objective was to determine if and how clusters differed in terms of BD related factors (e.g., subtypes, sleep, medications) and sociodemographic differences such as age of participants. From the BADAS (Bipolar Affective Disorder and older Adults) Study, we identified 281adults with BD (M = 44.27 years of age, range 19–81), recruited via social media. ResultsAll clusters significantly differed across all grouping variables except symptoms of hypo/mania due to low frequency. Across clusters, perceived cognitive failures and BD symptoms increased in lockstep; that is, those reporting more cognitive errors also reported significantly higher symptoms of both depression and hypo/mania. As hypothesized, they also reported significantly lower psychological well-being.ConclusionsAge did not significantly differ across clusters in contrast to existing research in which cognitive loss is objectively measured. That is, perceived cognitive errors are significantly associated with lower psychological well-being for both young and older adults with BD.

Network Analysis of Association Between Problematic Social Network Use and Alexithymia in Freshmen.

Exploring the core and bridge nodes in problematic social network use and alexithymia among freshmen to provide a basis for understanding the relationship and interventions. A total of 4057 first-year students from four universities in Shandong Province were chosen and surveyed with the Problematic Mobile Social Media Use Assessment Questionnaire and the Toronto Alexithymia Scale (TAS). Network analysis was performed using R to estimate the connections between nodes. Centrality and predictability indicators were used to identify key nodes, with accuracy and stability validation techniques applied. Gender and residence differences in the network structure were also examined. In the problematic social network use network, the nodes with the highest expected influence were P16 (excessive swiping) and P14 (lack of control over phone usage). In the problematic social network use-alexithymia network, cognitive failure had the highest strength (strength = 1.155) and centrality. Difficulty identifying feelings (bridgestrength = 0.32), externally oriented thoughts (bridgestrength = 0.24), and cognitive failure (bridgestrength = 0.19) were key bridge nodes. No significant differences were found in the network structure across gender and residence, though the network was tightly connected. Cognitive failure plays a central role in problematic social network use among freshmen. Difficulty identifying feelings, externally oriented thoughts, and cognitive failure are critical in linking problematic social network use with alexithymia.

Mental Health and Medical Error among Nursing Staffs at Korean Medicine Clinics: a first survey in South Korea.

Nurses face mental health issues like emotional labor, stress, and depression, increasing the risk of medical errors. This study assesses the mental health and medical errors among nurses in Korean medicine clinics in South Korea. The cross-sectional analysis involved 83 nurses, examining relationships between emotional labor, stress, depression, cognitive failure, Hwa-byung (HB) (a syndrome of suppressed anger in Korean culture), and medical errors. It identified factors associated with HB and medical errors using multiple regression analysis, presenting their odds ratios (ORs) with 95% confidence intervals (CIs). The findings revealed a current HB prevalence of 19.28% and a 6-month medical error prevalence of 16.87% among participants. The regression analysis showed that higher levels of depression (OR = 1.368, 95% CI = 1.098 to 1.703, p = 0.005), cognitive failure (OR = 1.072, 95% CI = 1.011 to 1.136, p = 0.020), and HB trait (OR = 1.136, 95% CI = 1.005 to 1.284, p = 0.041) significantly correlated with HB presence. This groundbreaking study on this previously under-researched nurse workforce highlights the critical need for comprehensive mental health care, with the objective of significantly enhancing their mental well-being and improving their overall work environment.

Exploring the role of galectin-9 and artemin as biomarkers in long COVID with chronic fatigue syndrome: links to inflammation and cognitive function.

This study aimed to assess plasma galectin-9 (Gal-9) and artemin (ARTN) concentrations as potential biomarkers to differentiate individuals with Long COVID (LC) patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) from SARS-CoV-2 recovered (R) and healthy controls (HCs). Receiver operating characteristic (ROC) curve analysis determined a cut-off value of plasma Gal-9 and ARTN to differentiate LC patients from the R group and HCs in two independent cohorts. Positive correlations were observed between elevated plasma Gal-9 levels and inflammatory markers (e.g. SAA and IP-10), as well as sCD14 and I-FABP in LC patients. Gal-9 also exhibited a positive correlation with cognitive failure scores, suggesting its potential role in cognitive impairment in LC patients with ME/CFS. This study highlights plasma Gal-9 and/or ARTN as sensitive screening biomarkers for discriminating LC patients from controls. Notably, the elevation of LPS-binding protein in LC patients, as has been observed in HIV infected individuals, suggests microbial translocation. However, despite elevated Gal-9, we found a significant decline in ARTN levels in the plasma of people living with HIV (PLWH). Our study provides a novel and important role for Gal-9/ARTN in LC pathogenesis.

Internet gaming disorder and cognitive failures in daily life among university students: the mediating role of sleep quality and the moderating role of mindfulness

Internet gaming disorder and cognitive failures in daily life among university students: the mediating role of sleep quality and the moderating role of mindfulness

A meta-analysis on the relationship between subjective cognitive failures as measured by thecognitive failures questionnaire (CFQ) and objective performance on executive function tasks.

The Cognitive Failures Questionnaire (CFQ) has been widely used as a measure of subjective cognitive function in everyday life for decades. However, the evidence on how it relates to objective performance on executive function tasks is mixed. One possible reason for these mixed results is that the CFQ has selective relationships with some aspects of executive function and not others. Here, therefore, we classified tasks according to an influential framework of executive functions-switching, updating, inhibition, and we also considered the Sustained Attention to Response Task (SART) as a category because it was custom designed to gauge cognitive failures. We synthesized a large body of available evidence and performed four Bayesian meta-analyses on the relationship between CFQ scores and objective performance on executive function tasks in these four categories. Results suggested that CFQ scores were associated with objective performance on SART (18 effect sizes, μ = -.19, BF10 = 18.03, i.e., 18.03 times more evidence of a relationship versus no relationship), updating working memory (49 effect sizes, μ = -.06, BF10 = 17.80), and inhibition tasks (41 effect sizes, μ = -.07, BF10 = 15.40), whereas there was not definitive evidence regarding switching (34 effect sizes, μ = -.06, BF10 = .50, i.e., two times greater evidence for no relationship). This suggests that subjective cognitive function can predict objective performance on at least some executive function tasks. We discuss methodological and theoretical factors that constrain the maximum observable correlation and consider the relative insights that subjective measures versus task performance provide.

Fading Focus: Addressing the Association Between Challenge Stressors, Role Blurring, Insomnia, Fatigue, and Workplace Cognitive Failure.

The primary goal of the present study is to inspect the plausible job-related (i.e., challenge stressors and role blurring) and individual factors (i.e., fatigue and insomnia) that potentially lead to work-related cognitive failures among healthcare staff. Through the judgmental sampling technique, data was collected from healthcare personnel in Iran. The results revealed that challenge stressors in the form of time pressure, job responsibility, and work overload are significantly related to role blurring. Moreover, role blurring increases fatigue and insomnia among medical staff, and both insomnia and fatigue cause workplace cognitive failure. The results also confirm the mediation effect of role blurring in the association between challenge stressors, insomnia, and fatigue. According to the results, insomnia and fatigue similarly mediate the role blurring on workplace cognitive failure association. Theoretical implications, useful suggestions for practitioners, and prospective research avenues are debated in the study.

Self-reported immune status and COVID-19 associated subjective cognitive functioning in post-COVID-19 syndrome: Examination of an Irish cohort.

Cognitive changes are very frequently reported by people with post-COVID-19 syndrome (PCS), but there is limited understanding of the underpinning mechanisms leading to these difficulties. It is possible that cognitive difficulties are related to immune status and/or low mood. The aim of the present study was to examine the relationship between immune status and cognitive functioning in PCS, while considering whether depression symptoms also influence this association. Participants were recruited in an online study of cognitive and psychological consequences of PCS, involving individuals attending a post-COVID clinic in an acute general hospital in Ireland, and a comparison sample of age- and sex-matched community controls who had also been infected with COVID-19 but had not experienced PCS. Participants with PCS (n=71) and community controls (n=50) completed the immune status questionnaire, Cognitive Failures Questionnaire (CFQ), Hospital Anxiety and Depression Scale (HADS), and the Functional Assessment of Chronic Illness Therapy-Fatigue Scale (FACIT-F). Significant differences were observed between groups in terms of perceived immune status, perceived cognitive function, depression scores, and fatigue, with the "PCS" group reporting lower immune status, more cognitive difficulties, and higher levels of depression and fatigue. Regression analysis in the PCS group indicated that immune status and depression significantly contributed to variance in subjective cognitive functioning, with immune status remaining a significant predictor of cognitive functioning scores even when accounting for depression, fatigue, and other covariates related to PCS, such as Body Mass Index(BMI). Our findings suggest that subjective cognitive functioning is influenced by self-reported immune status in PCS, emphasising the importance of immune status, cognitive, and mood screening as part of routine clinical care in PCS.

Examining factors associated with self-reported cognitive functioning in elite military settings: considerations of combat experiences and post-traumatic stress symptomology

Exposure to traumatic events is associated with post-traumatic stress symptomology (PTSS) in a variety of populations. PTSS is also associated with self-reported everyday cognitive failures, which are acknowledged attentional lapses experienced in one’s naturalistic everyday environment. While a growing literature suggests that PTSS is associated with both traumatic events and attentional functions, little is known regarding similar associations in elite military cohorts, such as Special Operations Forces (SOF) personnel. Herein, we investigate if prior combat experience is associated with everyday cognitive failures, while considering the possible mediating role of PTSS. SOF personnel (N = 119) completed self-report questionnaires assessing prior combat experience, PTSS, and everyday cognitive failures. Direct and indirect associations between these metrics were examined using structural equation modeling. Mediation analyses revealed that the correspondence between combat experiences and everyday cognitive failures is mediated by the severity of subclinical levels of PTSS. Such findings suggest that greater attention to subclinical PTSS is warranted due to its significant association with everyday cognitive failures that may contribute to deleterious mission-related failures in high-demand tactical professionals, such as SOF.

Roles of Family Functioning and Cognitive Failure in Predicting High-risk Behaviors Among Students with a History of Learning Disability

Background: Students with learning disabilities may face challenges associated with their condition, which could contribute to engaging in risky behaviors. Objectives: This study aimed to investigate the effects of family functioning and cognitive failure in predicting high-risk behaviors among students with a history of learning disabilities. Methods: The statistical population of this descriptive-correlational study included all high school students with a history of learning disabilities in Ahvaz, Iran, in 2023. Convenience sampling with informed consent was employed to select 158 high school students with a history of learning disabilities as the research sample. Data were collected using the High-Risk Behavior Scale, Family Functioning Questionnaire, and Cognitive Failure Questionnaire. Pearson’s correlation coefficient and stepwise regression were used for data analysis. Results: The results indicated a significant negative relationship between family functioning and high-risk behaviors (r = -0.41, P < 0.001). Conversely, there was a significant positive relationship between cognitive failure and high-risk behaviors (r = 0.49, P < 0.001). Family functioning and cognitive failure together predicted 29.4% of the variance in students' high-risk behaviors. Conclusions: These findings suggest that family functioning and cognitive abilities are important factors to consider in understanding high-risk behaviors. Further research using longitudinal or experimental designs is needed to explore the causal relationships between these variables.