Cognitive Work Research Articles

Witnessing their mother’s acute and prolonged stress affects executive functioning in children

Stress can detrimentally affect physical and mental health, especially during childhood. During this critical period, parental bonds can foster resilience or amplify stress. This study explored whether mothers’ everyday stress can act as a source of childhood stress, affecting children’s executive functioning. 76 healthy mother-child dyads participated, with mothers assigned to a stress-inducing or stress-free condition. Children observed their mothers and were subsequently tested for cognitive flexibility and working memory. Subjective stress, heart rate, and cortisol were measured repeatedly in mothers and children, alongside everyday stress perceptions. Linear mixed models showed that children’s acute stress response was associated with impaired cognitive flexibility. Maternal stress, both acute and past-month, was a better predictor of children’s cognitive performance than children’s own stress. Quadratic relationships indicated the highest error rates at very low and high maternal stress. We found no evidence that children’s working memory was impaired by their own or their mothers’ stress. Although expected covariations of acute or prolonged stress between mothers and children were not observed, an interaction between maternal past-month stress and acute stress condition provided insights into adaptive mechanisms in children. These findings underscore the significant impact of maternal stress on children’s executive functioning, illustrating how parental experiences shape children’s everyday outcomes.

Effects of open-skill and closed-skill exercise on subthreshold depression in female adolescents: A randomized controlled trial

BackgroundSubthreshold depression (SD) affects a significant proportion of adolescent females, posing a risk of major depression in later life. This study examines the effects of open-skill exercise (OSE) and closed-skill exercise (CSE) on SD, executive function (EF), and emotional states in female adolescents. MethodsA double-blind randomized controlled trial involved 95 female adolescents (mean age = 16.73 ± 0.42 years) with SD symptoms. Participants were assigned to OSE, CSE, or control (CON) groups and underwent an 8-week exercise program. Primary outcomes were assessed using the Beck Depression Inventory (BDI-13) and the Center for Epidemiological Studies Depression Scale (CES-D), with secondary outcomes including EF tasks and emotional assessments. Differences were examined using generalized linear mixed models with intention-to-treat and multiple imputation. ResultsBoth OSE and CSE significantly reduced depressive symptoms, with CSE showing greater improvement. EF assessments showed enhanced cognitive flexibility and working memory in both exercise groups at 4 weeks, and superior inhibitory control and cognitive flexibility in the CSE group at 8 weeks. Emotional assessments indicated a notable reduction in negative emotions in the CSE group after 8 weeks. ConclusionsBoth OSE and CSE reduce SD symptoms in female adolescents, with CSE providing more sustained benefits for EF and emotional states. Further research on exercise interventions for mental health is warranted.Trial registration number: ChiCTR2400081139

Scaffolding patient agency: Conceptualising readers' cognitive work in the comic gutter.

A life-limiting illness can erode an individual's positive sense of self. Storytelling can help counteract this, through scaffolding patients' agency and supporting them in acting to change something which matters to them. This article explains how visual stories - comics - are used within the PATCHATT intervention to support the redevelopment of a person's agential self. Through the provision of a conceptual map, this article explores the gutter as a liminal space, arguing for the importance of the deep reader engagement which takes place there. It uses Bob's comic, a story used within PATCHATT, to explore how reflexivity and imagination work together within the liminal space of the gutter to stimulate and enhance palliative care patients' agential change leadership. It concludes by considering the implications of the argument put forward for palliative care practice.

Executive functions in older adults with generalised anxiety disorder and healthy controls: Associations with heart rate variability, brain-derived neurotrophic factor, and physical fitness

Executive functions (EF) decline with age and this decline in older adults with generalised anxiety disorder (GAD) may be influenced by heart rate variability (HRV), brain-derived neurotrophic factor (BDNF), and physical fitness. Understanding these relationships is important for tailored treatments in this population. In this study, 51 adults with GAD (M age = 66.46, SD = 4.08) and 51 healthy controls (M age = 67.67, SD = 4.04) were assessed on cognitive inhibition (Stroop task), shifting (Trails part 4), flexibility (Wisconsin Card Sorting Test – Perseverative errors), working memory (Digit Span Backwards), IQ (Wechsler Abbreviated Scale of Intelligence), high frequency HRV, serum mature BDNF levels, and VO2 max. Results indicated that participants with GAD exhibited better cognitive inhibition compared to controls, with no general reduction in EF. Cognitive inhibition was predicted by gender, HRV, and BDNF levels, while cognitive shifting was predicted by gender and IQ, and cognitive flexibility and working memory by IQ. The enhanced cognitive inhibition in GAD participants might stem from maladaptive use of this function, characteristic of GAD, or protection from EF decline due to normal HRV. Increased BDNF levels, possibly due to good fitness, or compensatory mechanisms related to the disorder, might also play a role. These findings highlight the complexity of EF and related mechanisms in GAD, highlighting the need for interventions that consider both cognitive and physiological factors for optimal outcomes.

Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events.

Decades of research into the function of the medial temporal lobe has driven curiosity around clinical outcomes associated with hippocampal dysfunction, including psychosis. Post-mortem analyses of brain tissue from human schizophrenia brain show decreased expression of the NMDAR subunit GluN1 confined to the dentate gyrus with evidence of downstream hippocampal hyperactivity in CA3 and CA1. Little is known about the mechanisms of the emergence of hippocampal hyperactivity as a putative psychosis biomarker. We have developed a reverse-translation mouse to study critical neural features. We had previously studied a dentate gyrus (DG)-specific GluN1 KO, which displays hippocampal hyperactivity and a psychosis-relevant behavioral phenotype. Here, we expressed an inhibitory DREADD (pAAV-CaMKIIa-hM4D(Gi)-mCherry) in granule cells of the mouse dentate gyrus, and continuously inhibited the region for 21 days in adolescent (6 weeks) and adult (10 weeks) C57BL/6 J mice with DREADD agonist Compound 21 (C21). Following this period, we quantified activity in the hippocampal subfields by assessing cFos expression, hippocampally mediated behaviors, and hippocampal local field potential with an intracerebral probe with continual monitoring over time. DG inhibition during adolescence generates an increase in hippocampal activity in CA3 and CA1, impairs social cognition and spatial working memory, as well as shows evidence of increased activity in local field potentials as spontaneous synchronous bursts of activity, which we term hyper-synchronous events (HSEs) in hippocampus. The same DG inhibition delivered during adulthood in the mouse lacks these outcomes. These results suggest a sensitive period in development in which the hippocampus is susceptible to DG inhibition resulting in hippocampal hyperactivity and psychosis-like behavioral outcomes.

Trends in South Korean Medical Device Development for Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder: Narrative Review.

Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are among the most prevalent mental disorders among school-aged youth in South Korea and may play a role in the increasing pressures on teachers and school-based special education programming. A lack of support for special education; tensions between teachers, students, and parents; and limited backup for teacher absences are common complaints among Korean educators. New innovations in technology to screen and treat ADHD and ASD may offer relief to students, parents, and teachers through earlier and efficient diagnosis; access to treatment options; and ultimately, better-managed care and expectations. This narrative literature review provides an account of medical device use and development in South Korea for the diagnosis and management of ADHD and ASD and highlights research gaps. A narrative review was conducted across 4 databases (PubMed, Korean National Assembly Library, Scopus, and PsycINFO). Journal articles, dissertations, and government research and development reports were included if they discussed medical devices for ADHD and ASD. Only Korean or English papers were included. Resources were excluded if they did not correspond to the research objective or did not discuss at least 1 topic about medical devices for ADHD and ASD. Journal articles were excluded if they were not peer reviewed. Resources were limited to publications between 2013 and July 22, 2024. A total of 1794 records about trends in Korean medical device development were categorized into 2 major groups: digital therapeutics and traditional therapy. Digital therapeutics resulted in 5 subgroups: virtual reality and artificial intelligence, machine learning and robot, gaming and visual contents, eye-feedback and movement intervention, and electroencephalography and neurofeedback. Traditional therapy resulted in 3 subgroups: cognitive behavioral therapy and working memory; diagnosis and rating scale; and musical, literary therapy, and mindfulness-based stress reduction. Digital therapeutics using artificial intelligence, machine learning, and electroencephalography technologies account for the biggest portions of development in South Korea, rather than traditional therapies. Most resources, 94.15% (1689/1794), were from the Korean National Assembly Library. Limitations include small sizes of populations to conclude findings in many articles, a lower number of articles discussing medical devices for ASD, and a majority of articles being dissertations. Emerging digital medical devices and those integrated with traditional therapies are important solutions to reducing the prevalence rates of ADHD and ASD in South Korea by promoting early diagnosis and intervention. Furthermore, their application will relieve pressures on teachers and school-based special education programming by providing direct supporting resources to students with ADHD or ASD. Future development of medical devices for ADHD and ASD is predicted to heavily rely on digital technologies, such as those that sense people's behaviors, eye movement, and brainwaves.

The Bilingual Dual-path model

Abstract Experimental research has yielded many important psycholinguistic findings in bi-/multilingualism. However, cognitive computational models of sentence processing were limited to the single-language case until recently. In this methodological review, we discuss cognitive modelling work that uses the Bilingual Dual-path model to simulate experimental research on bilingual sentence production, processing, and development. As a detailed example of such work, we then report on new simulations conducted with the model. Finally, we suggest directions for future cognitive modelling research using this model.

The Association of the Oral Microbiota with Cognitive Functioning in Adolescence.

Background: A growing body of research supports the role of the microbial communities residing in the digestive system in the host's cognitive functioning. Most of these studies have been focused on the gut microbiome and its association with clinical phenotypes in middle-aged and older adults. There is an insufficiency of population-based research exploring the association of normative cognitive functioning with the microbiome particularly with the oral microbiota. Methods: In this study, using metagenomics and metabolomics, we characterized the salivary microbiome diversity in a sample of 51 males of Hispanic and African American origin aged 12-18 years and explored the associations between the microbiome and the youths' cognitive performance captured with the Kaufman Assessment Battery for Children II (KABC-II). Results: Several bacterial species of the oral microbiota and related metabolic pathways were associated with cognitive function. In particular, we found negative associations between indicators of general intelligence and the relative abundance of Bacteroidetes and Lachnospiraceae and positive associations with Bifidobacteriaceae and Prevotella histicola sp. Among metabolic pathways, the super pathways related to bacterial cell division and GABA metabolism were linked to cognitive function. Conclusions: The results of our work are consistent with the literature reporting on the association between microbiota and cognitive function and support further population work to elucidate the potential for a healthy oral microbiome to improve cognitive health.

Flexible Work in the Public Sector: A Dual Perspective on Cognitive Benefits and Costs in Remote Work Environments

The COVID-19 pandemic has accelerated the adoption of flexible work arrangements within the Italian public administration. While much of the existing research has focused on the drawbacks of such arrangements, there has been less exploration of their benefits. Cognitive demands related to the structure of work activities, planning of working hours, planning of workplaces, and coordination with others, under flexible working conditions, might be considered as job resources that act as challenging demands within the Job Demand-Resource (JD-R) model. This study aimed to explore how the “cognitive challenge of flexible work” (CCFW) impact job satisfaction through home-based performance, taking into account the role of weekly working hours on home-based performance. Furthermore, the potential moderating role of cognitive and physical job demands between CCFW and home-based performance was explored. Using structural equation modeling on data from 484 public employees, the findings confirmed the positive impact of the structure of work tasks and planning of working times on both job satisfaction and home-based performance. In addition, cognitive demands (i.e., perception of cognitive work overload) played a moderating role in the mediated relationship between coordinating with others on job satisfaction and the structure of working tasks on job satisfaction through home-based performance.

Gesture size affects numerical estimates in quantifier comprehension.

People think and talk about numerical magnitude in terms of space, and co-speech gestures reflect this, with English speakers using expansive gestures when talking about greater quantities. Existing gestural research on the spatial conceptualization of number has largely looked at gesture production, but we do not know whether gestures can influence the interpretation of imprecise or underspecified numerical expressions such as quantifiers. Looking at the quantifier several as a test case, this study investigates the influence of manual inwards-directed (i.e., hands move closer the torso) and outwards-directed (i.e., hands move away from the torso) co-speech gestures on comprehenders' conceptualization of quantities associated with several through three preregistered experiments. Our results suggest that gesture modulates the interpretation of several such that speakers moving their hands outwards and thereby creating space between their hands lead to higher quantity estimates, compared to speakers not gesturing, or moving their hands inwards. We discuss the implications of our findings for future work in numerical cognition, multimodal communication, and pragmatics. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Individual Responses to Paradox: The Articulation Between Emotion and Cognition

This article examines how emotions and cognition work together to shape individual responses to paradox. While much-existing research focuses on organizational response or the effect that either emotions or cognitions have on individual responses, our work shows how emotion and cognition work together to create individual responses. Based on a qualitative study of a global organization with employees who regularly face paradoxes, we found two cognitive appraisals (perception regarding the difficulty of managing paradoxical tensions and self-perception of leadership role) that either generate emotion or regulate response. By examining the interlinking of appraisal – emotion – appraisal – response, we identify two mechanisms that demonstrate the articulation between emotion and cognition: the nonregulated response and the regulated response. We contribute to the existing literature by detailing each mechanism and explaining how emotions and cognition work together to shape individual responses.

What Super Productive People Do Differently

This article explores seven habits shown through research to distinguish highly productive individuals from average performers. Each habit is grounded in academic literature and illustrated with real-world industry examples. The habits include planning the next day's schedule in advance to be proactive rather than reactive. Minimizing distractions like notifications to focus deeply on priorities. Batching similar tasks together to maintain cognitive momentum. Automating repetitive tasks to streamline workflow. Enforcing strict boundaries between work and personal time to prevent burnout. Dedicating time to continuous self-improvement through skills development. And scheduling regular "deep work" sessions for uninterrupted focus on complex cognitive work. The article argues that organizational leaders who foster a culture supporting these evidence-based productivity strategies can cultivate high-performing teams consistently delivering quality outcomes despite demanding workloads. adopting some principles could significantly increase organizational output.

Structural labour market change, cognitive work, and entry to parenthood in Germany

Technological change and globalization have caused unprecedented transformations of labour markets, resulting in a growing division between workers who perform cognitive vs non-cognitive tasks. To date, only few studies have addressed the fertility effects of these long-term structural changes. This study fills that gap. We measure the cognitive task content of occupations using data from the Employment Survey of the German Federal Institute for Vocational Education and Training, which we link to individual histories from the German Socio-Economic Panel 1984–2018. We find that women and men with non-cognitive jobs are increasingly less likely to enter parenthood; this is reflected in lower first-birth intensities but also in higher probabilities of childlessness compared with workers in highly cognitive jobs. These findings imply that structural shifts in the labour market are exacerbating disparities between low-skilled and highly skilled individuals, not only within the labour market but also in the realm of family formation.

Complexity in Systemic Cognition: Theoretical Explorations with Agent-Based Modeling

This paper presents a systemic view of human cognition that suggests complexityis an essential feature of such a system. It draws on the embodied, distributed, and extended cognition paradigms to outline the elements and the mechanisms that define cognition. In doing so, it uses an agent-based computational model (the TS 1.0.5Model) with a focus on learning mechanisms as they reflect on individual competence to gain insights on how cognition works. Results indicate that cognitive dynamics do not depend solely on macro structural elements, nor do they depend uniquely on individual characteristics. Instead, more insights and understanding are available through the consideration of all elements together as they co-evolve and interact over time. This perspective illustrates the essential role of how we define the meso domain and constitutes a clear indication that cognitive systems are indeed complex.

A therapeutic small molecule enhances γ-oscillations and improves cognition/memory in Alzheimer’s disease model mice

Brain rhythms provide the timing for recruitment of brain activity required for linking together neuronal ensembles engaged in specific tasks. The γ-oscillations (30 to 120 Hz) orchestrate neuronal circuits underlying cognitive processes and working memory. These oscillations are reduced in numerous neurological and psychiatric disorders, including early cognitive decline in Alzheimer's disease (AD). Here, we report on a potent brain-permeable small molecule, DDL-920 that increases γ-oscillations and improves cognition/memory in a mouse model of AD, thus showing promise as a class of therapeutics for AD. We employed anatomical, in vitro and in vivo electrophysiological, and behavioral methods to examine the effects of our lead therapeutic candidate small molecule. As a novel in central nervous system pharmacotherapy, our lead molecule acts as a potent, efficacious, and selective negative allosteric modulator of the γ-aminobutyric acid type A receptors most likely assembled from α1β2δ subunits. These receptors, identified through anatomical and pharmacological means, underlie the tonic inhibition of parvalbumin (PV) expressing interneurons (PV+INs) critically involved in the generation of γ-oscillations. When orally administered twice daily for 2 wk, DDL-920 restored the cognitive/memory impairments of 3- to 4-mo-old AD model mice as measured by their performance in the Barnes maze. Our approach is unique as it is meant to enhance cognitive performance and working memory in a state-dependent manner by engaging and amplifying the brain's endogenous γ-oscillations through enhancing the function of PV+INs.

Individual differences in attention and working memory modulate the process of tone merging: evidence from Macau Cantonese

Cognitive functions, including attention and working memory, have been recognized to be associated with tone processing. However, it remains unclear how these cognitive functions might modulate the process of tone merging. In Macau Cantonese, three pairs of tones are currently undergoing or have completed merging, exhibiting different rates and ranges of merging within the speech community, providing a valuable opportunity to investigate this issue. Through a perception task, a production task, and a series of cognitive function tasks, we examined differences in cognitive performances among individuals distinguishing different tone pairs and explored the correlations between various indices of tone processing and cognitive functions. The results revealed that the completed merging of the T2–T5 pair showed no significant correlation with cognitive functions in perception and production. The T3–T6 pair, with an intermediate merging speed, exhibited a significant positive correlation between cognitive functions and both their perception and production. In contrast, the T4–T6 pair, characterized by a slower merging speed, showed a correlation only in the perception modality. Our findings suggested that cognitive functions affect tones at different stages of the merging process, influencing their perception and production in distinct ways. The results provide a novel perspective on the origin of tonal variation and the relationship between perception and production.

The feasibility and effectiveness of remote cognitive training on cognitive function and work performance in workers.

We aimed to determine whether remote cognitive training (CT) is feasible and has the potential to improve cognitive function and work performance in Japanese workers. From June to September 2020, this intervention time series study enrolled workers aged 18-65 years from 10 companies located in a metropolitan area of Japan. Cognitive function tests and self-administered questionnaires were completed by the participants three times: at baseline, after 12 weeks of CT, and after a further 12 weeks following cessation. We measured work performance with the question: "How would you rate your performance (compared with your optimum performance) over the past 4 weeks?" Responses were made via a visual analog scale (0-100). Cognitive function was assessed using the THINC-integrated tool, which is a brief, objective computerized cognitive assessment battery. For our computerized remote CT intervention, BrainHQ was used on the basis of our scientific rationale and the empirical literature. We recommended three 20-min sessions of BrainHQ per week and sent participants three reminders. In total, 119 participants were recruited to this study. Only 22.7% of the subjects achieved the recommended training time of 720 min over 12 weeks. The median training time was used to divide participants into long and short- training groups. The long-training group showed a greater improvement in attention and executive function than the short-training group but there was no significant improvement in work performance after CT compared to baseline. Our results suggest that although remote CT was not feasible enough, the effects on cognitive function can be expected by increasing training time and motivation.

Brain Responses Difference between Sexes for Strong Desire to Void: A Functional Magnetic Resonance Imaging Study in Adults Based on Graph Theory.

Background: The alternations of brain responses to a strong desire to void were unclear, and the gender differences under the strong desire to void remain controversial. The present study aims to identify the functional brain network's topologic property changes evoked by a strong desire to void in healthy male and female adults with synchronous urodynamics using a graph theory analysis. Methods: The bladders of eleven healthy males and eleven females were filled via a catheter using a specific infusion and withdrawal pattern. A resting-state functional magnetic resonance imaging (fMRI) was performed on the enrolled subjects, scanning under both the empty bladder and strong desire to void states. An automated anatomical labeling (AAL) atlas was used to identify the ninety cortical and subcortical regions. Pearson's correlation calculations were performed to establish a brain connection matrix. A paired t-test (p < 0.05) and Bonferroni correction were applied to identify the significant statistical differences in topological properties between the two states, including small-world network property parameters [gamma (γ) and lambda (λ)], characteristic path length (Lp), clustering coefficient (Cp), global efficiency (Eglob), local efficiency (Eloc), and regional nodal efficiency (Enodal). Results: The final data suggested that females and males had different brain response patterns to a strong desire to void, compared with an empty bladder state. Conclusions: More brain regions involving emotion, cognition, and social work were active in females, and males might obtain a better urinary continence via a compensatory mechanism.

The Role of Family Physicians in Children's Sleep.

Sleep holds significant importance for maintaining health and aiding in illness recovery. Its deprivation impacts all human organ systems, from cognitive function, social interaction, and work capacity to cellular regeneration and immune function. Therefore, sleep plays a crucial role in our body and maintaining health and well-being. Given its importance and close relationship with the neurodevelopment and growth of children and adolescents, this topic is highly significant in pediatric and adolescent health consultations. Family physicians, due to their proximity and understanding of the individual within their family, have the prerogative to contribute to family literacy, empower them, and significantly enhance the quality of life and overall health.

Self-Regulation in Eating Behaviors: The Role of Executive Function in Response to Food Stimuli.

Human nutrition is characterized by both automatic and self-regulated processes. One of the dimensions that may be employed in monitoring eating behaviors is the cognitive control played by the executive functions (EFs). The role of EFs in affecting eating behaviors has been assessed in empirical studies, but further analyses are needed in a current society characterized by a food-abundant environment. Accordingly, this study attempted to evaluate the association between weight status and executive functions in response to food-related stimuli. One hundred and forty-four young adults took part in the study (25.7% in overweight condition). The participants completed a set of computerized cognitive tasks to assess cognitive and motor inhibition and working memory in two different conditions: (i) classic versions of the tasks and (ii) modified versions with food cues. The results indicate that food stimuli may influence executive performance and that there is an association between food cue-related executive functioning, particularly in the domain of motor inhibition, and working memory. These results suggest that self-regulation in nutrition may involve executive control. Although further studies are needed, this work suggests the importance of a multidimensional perspective in the analysis of eating behaviors and the relevance of EFs in monitoring our approach to food stimuli in an environmental context.