This research looks into the association between fishing and microplastic contamination across countries, with a particular focus on how the growth of microplastic levels can impact fishery production. Through the use of a mixed-effect model we were able to look through data from 100 nations during the period 1990-2021, where fishery yield data was extracted from The World Bank and microplastic concentration data was obtained from the National Centers for Environmental Information; population data served as a control variable in our analysis. We found that there is indeed a significant negative correlation between levels of microplastics and fishing yield: an increase by 1 piece of microplastic per cubic meter leads to decrease in fishing yield by anything between 65 and 100 metric tonnes (95% confidence interval). This relationship held true for about 93% of all coastal countries studied. To accommodate for differences amongst nations, we introduced random intercepts and slopes in our mixed-effect model which helped capture variations specific to each country while still identifying an overarching pattern. The research we are doing is on the connection between fish catches and microplastic pollution which takes place in the different countries of the world, where we focus more on how high microplastic levels influence fishery production. Having made use of a mixed-effect model, we have been able to look at data that represents 100 nations within the period of time between 1990 and 2021; The World Bank provided us with fishery yield data while microplastic concentration data came from the National Centers for Environmental Information. In addition to these variables, population data was used as a control variable. The summary of our analysis points towards a significant inverse relationship noted between microplastic levels and fishing yield: an increase by one piece of plastic results in a decline by somewhere between 65 to 100 metric tonnes (95% confidence interval). This generalization held true for about 93% coastal countries considered under this study. To capture specific variations among nations but also identify an overall trend line while dealing with inter-country variability, random intercepts and slope components were included as part of our mixed-effect model methodology.