The north and central coast of Chile is influenced by El Niño-Southern Oscillation (ENSO) through oceanic and atmospheric teleconnections. However, it also experiences episodic oceanic warmings off central Chile (30°S) lasting a few months that are not necessarily associated with ENSO. These episodes, called “Chile Niño” events, besides their ecological and socio-economical impacts, have also the potential to influence tropical Pacific variability. Here, we investigate how realistically the models in the Coupled Model Intercomparison Project (CMIP, Phases 5 and 6) simulate Chile Niño/Niña (CN) events, and quantify their changes under anthropogenic forcing. Despite limitations of the global models in simulating realistically coastal upwelling dynamics, we show that they simulate reasonably well the observed spatial pattern, amplitude and seasonal evolution of CN events. They however fail to properly represent the positive skewness from observations. The analysis of a sub-group of models (36) that simulate ENSO realistically reveals that CN events increase in amplitude and variance in the future climate with no changes in their frequency of occurence. This is interpreted as resulting from compensating effects amongst changes in remote drivers and local feedbacks. In particular, ENSO variance increases while that of the South Pacific Oscillation decreases. Conversely, we found that while the Wind-Evaporation-SST feedback tends to increase and the coupling between mixed-layer depth and SST weakens, favoring the development of CN events, the thermocline and wind-SST feedbacks decrease. However, only the change in the thermocline feedback is correlated to changes in CN variance amongst the models, suggesting a dominant role of local oceanic stratification changes in constraining the sensitivity of CN to global warming.