Following a brief review of the early developments in the field, we discuss a few new advances in the distribution of bright galaxies which occured after the extensive review paper by Oort (1983) We show that the large scale structure, shells, filaments and/or sheets, may bias the determination of the velocity dispersion in clusters of galaxies and that the boundaries of the voids may often be biassed by the clusters and groups velocity dispersion.Of interest are the very large structures selected on catalogs of clusters of galaxies. The “Local Structure” claimed by Tully seems to be somewhat flattened and about parallel to the plane of the Local Supercluster. If the structure is real the alignement is relevant in relation to the physical mechanisms at work at the time of formation. Noticeable progress has been done in the measurement of the large scale velocity field. Large scale motions may somewhat bias the study of the topology of the Universe.Relevant work has be done on the shape of the boundaries of the voids and observational work is progressing to detect faint galaxies in voids and determine their charactestics. This is important also in relation to the theory of biassed galaxy formation. To better focus the observational problem and eventually related biasses, we give some statistics on dwarf galaxies in the Virgo cluster.