Cluster Of Manifestations Research Articles

A RETROSPECITVE ANALYSIS ON VARIOUS CLINICAL OUTCOMES OF DENGUE FEVER IN A TERITIARY CARE HOSPITAL

Dengue is a vector borne illness caused via dengue virus infected female Aedes mosquitoes. The main viral strains are DEN1, DEN2, DEN3 and DEN4. A various cluster of manifestations are included in dengue as the disease progresses. This observational study was conducted at tertiary care hospitals in and around Mangalore from 2015 to 2019, on confirmed cases of Dengue via immunological studies. Various clinical, laboratory and radiological parameters were recorded and assessed statistically later. Dengue was more common in young males (58.9%). Common presentations were fever with headache (94%), hypotension and abdominal pain (15%). Thrombocytopenia (88.4) and leucopenia (48.3%) were the commonest cytological findings. Deranged LFT (39.1%)with Hyponatremina (35.3%) and low bicarbonate (78.3%)were also seen. Cavitatory effusion was seen in 67% of patients with complications. Myocarditis was seen in 2%. Dengue despite being an easily preventable and usually self-limiting illness, the complications however can fatal. Especially in endemic areas, early diagnosis of the disease using clinical, laboratory and radiological assessment is necessary to avoid it being confused with other infections due to its overlapping of symptoms; and for preventing complications.

Chronic and high risk asthma in children.

High risk asthma signifies probable harm to the patient either because of periods of prolonged ventilatory defect, a clustering of manifestations indicating a poor prognosis, or severe life-threatening attacks. Ninety-five children referred to a university diagnostic center were classified as high risk and were selected from others with chronic asthma. These were observed at monthly intervals for at least two years. Ongoing disability usually resulted from failure to establish and eliminate causes and excessive dependence on adrenergic aerosols or corticosteroids. Case reports include patients with aspirin intolerance, allergic aspergillosis, α 1 -antitrypsin disease, misuse of adrenergic aerosols, and the effect of newer therapeutic agents in care of formerly unresponsive patients.