Chest X-ray Image Classification Research Articles

COVID‑19 detection from chest X-ray images using transfer learning

COVID-19 is a kind of coronavirus that appeared in China in the Province of Wuhan in December 2019. The most significant influence of this virus is its very highly contagious characteristic which may lead to death. The standard diagnosis of COVID-19 is based on swabs from the throat and nose, their sensitivity is not high enough and so they are prone to errors. Early diagnosis of COVID-19 disease is important to provide the chance of quick isolation of the suspected cases and to decrease the opportunity of infection in healthy people. In this research, a framework for chest X-ray image classification tasks based on deep learning is proposed to help in early diagnosis of COVID-19. The proposed framework contains two phases which are the pre-processing phase and classification phase which uses pre-trained convolution neural network models based on transfer learning. In the pre-processing phase, different image enhancements have been applied to full and segmented X-ray images to improve the classification performance of the CNN models. Two CNN pre-trained models have been used for classification which are VGG19 and EfficientNetB0. From experimental results, the best model achieved a sensitivity of 0.96, specificity of 0.94, precision of 0.9412, F1 score of 0.9505 and accuracy of 0.95 using enhanced full X-ray images for binary classification of chest X-ray images into COVID-19 or normal with VGG19. The proposed framework is promising and achieved a classification accuracy of 0.935 for 4-class classification.

Texture-Based Classification to Overcome Uncertainty between COVID-19 and Viral Pneumonia Using Machine Learning and Deep Learning Techniques

The SARS-CoV-2 virus, responsible for COVID-19, often manifests symptoms akin to viral pneumonia, complicating early detection and potentially leading to severe COVID pneumonia and long-term effects. Particularly affecting young individuals, the elderly, and those with weakened immune systems, the accurate classification of COVID-19 poses challenges, especially with highly dimensional image data. Past studies have faced limitations due to simplistic algorithms and small, biased datasets, yielding inaccurate results. In response, our study introduces a novel classification model that integrates advanced texture feature extraction methods, including GLCM, GLDM, and wavelet transform, within a deep learning framework. This innovative approach enables the effective classification of chest X-ray images into normal, COVID-19, and viral pneumonia categories, overcoming the limitations encountered in previous studies. Leveraging the unique textures inherent to each dataset class, our model achieves superior classification performance, even amidst the complexity and diversity of the data. Moreover, we present comprehensive numerical findings demonstrating the superiority of our approach over traditional methods. The numerical results highlight the accuracy (random forest (RF): 0.85; SVM (support vector machine): 0.70; deep learning neural network (DLNN): 0.92), recall (RF: 0.85, SVM: 0.74, DLNN: 0.93), precision (RF: 0.86, SVM: 0.71, DLNN: 0.87), and F1-Score (RF: 0.86, SVM: 0.72, DLNN: 0.89) of our proposed model. Our study represents a significant advancement in AI-based diagnostic systems for COVID-19 and pneumonia, promising improved patient outcomes and healthcare management strategies.

Application of Ensemble Learning in CXR Classification for Improving COVID-19 Diagnosis

This study delves into the vital task of classifying chest X-ray (CXR) samples, particularly those related to respiratory ailments, using advanced clinical image analysis and computer-aided radiology techniques. Its primary focus is on developing a classifier to accurately identify COVID-19 cases. Through the application of machine learning and computer vision methodologies, the research aims to enhance the precision of COVID-19 detection. It investigates the effectiveness of Histogram of Oriented Gradients (HOG) feature extraction techniques in conjunction with various classifiers, such as Support Vector Machine (SVM), Decision Tree (DT), Naive Bayes (NB), K-nearest neighbor (KNN), and Tree Bagger (TB), alongside an innovative ensemble learning approach. Results indicate impressive accuracy rates, with KNN, SVM, DT, NB, and TB all surpassing the 90% mark. However, the ensemble learning method emerges as the standout performer. By leveraging HOG features extracted from CXR images, this approach presents a robust solution for COVID-19 diagnosis, offering a powerful tool to address the diagnostic challenges posed by the pandemic.

An effective ensemble approach for classification of chest X-ray images having symptoms of COVID: A precautionary measure for the COVID-19 subvariants

In recent years many people have died due to COVID-19 infection. The death rate increases due to the lack of proper diagnosis and treatment. It can be detected by RT-PCR test and from chest X-rays. Chest X-ray images can identify lung diseases such as COVID-19, viral pneumonia, and tuberculosis (TB). Because many illnesses share similar patterns and diagnoses, radiologists and clinicians find it challenging to distinguish between them. This study uses convolutional neural networks (CNN) and ensemble models (VGG-19, ResNet50, vision transformer) to analyze chest X-ray images from internet sources to identify lung illness. The present research proposed an ensemble model comprised of VGG-19, ResNet50, and a vision transformer for the detection of COVID-19 and normal images with an accuracy of 92.46 percent and 94.52 % for the detection of COVID-19, normal and viral pneumonia respectively. Also, a comparative study has been conducted between CNN and ensemble approach for detecting COVID-19 and pneumonia disease from chest x-ray images. The proposed approach may also help in the early detection of other variants of COVID-19 such as JN.1, and HV.1 in the future.

Application of Ensemble Learning in CXR Classification for Enhancing COVID-19 Diagnosis

This study delves into the vital task of classifying chest X-ray (CXR) samples, particularly those related to respiratory ailments, using advanced clinical image analysis and computer-aided radiology techniques. Its primary focus is on developing a classifier to accurately identify COVID-19 cases. Through the application of machine learning and computer vision methodologies, the research aims to enhance the precision of COVID-19 detection. It investigates the effectiveness of Histogram of Oriented Gradients (HOG) feature extraction techniques in conjunction with various classifiers, such as Support Vector Machine (SVM), Decision Tree (DT), Naive Bayes (NB), K-nearest neighbor (KNN), and Tree Bagger (TB), alongside an innovative ensemble learning approach. Results indicate impressive accuracy rates, with KNN, SVM, DT, NB, and TB all surpassing the 90% mark. However, the ensemble learning method emerges as the standout performer. By leveraging HOG features extracted from CXR images, this approach presents a robust solution for COVID-19 diagnosis, offering a powerful tool to address the diagnostic challenges posed by the pandemic.

Multitask Adversarial Networks Based on Extensive Nonlinear Spiking Neuron Models.

Deep learning technology has been successfully used in Chest X-ray (CXR) images of COVID-19 patients. However, due to the characteristics of COVID-19 pneumonia and X-ray imaging, the deep learning methods still face many challenges, such as lower imaging quality, fewer training samples, complex radiological features and irregular shapes. To address these challenges, this study first introduces an extensive NSNP-like neuron model, and then proposes a multitask adversarial network architecture based on ENSNP-like neurons for chest X-ray images of COVID-19, called MAE-Net. The MAE-Net serves two tasks: (i) converting low-quality CXR images to high-quality images; (ii) classifying CXR images of COVID-19. The adversarial architecture of MAE-Net uses two generators and two discriminators, and two new loss functions have been introduced to guide the optimization of the network. The MAE-Net is tested on four benchmark COVID-19 CXR image datasets and compared them with eight deep learning models. The experimental results show that the proposed MAE-Net can enhance the conversion quality and the accuracy of image classification results.

Automated Classification of COVID-19 Chest X-ray Images Using Ensemble Machine Learning Methods

This study delves into the efficacy of ensemble machine learning techniques for classifying chest X-ray images into three distinct categories: Normal, COVID-19, and Lung Opacity. Employing the Random Forest Classifier and a rigorous k-5 cross-validation framework, we aimed to enhance diagnostic accuracy for one of the most urgent medical challenges today—rapid and reliable COVID-19 detection. The analysis revealed an average accuracy of 51%, with varying precision and recall across different folds. The F1-score remained consistently around 35%, indicating a need for improved balance between precision and recall. Visualizations such as performance metric trends and a confusion matrix provided further insight into the classifier's performance, highlighting a notable degree of misclassification. Despite moderate success in the automated classification of the images, our research illustrates the complexity of applying machine learning to medical imaging, especially in differentiating between diseases with overlapping radiographic features. The study’s findings emphasize the potential of machine learning models to support diagnostic processes and suggest the necessity of advanced pre-processing techniques and extended datasets for enhanced model training. The research contributes to the growing body of knowledge in computational diagnostics and underscores the importance of developing robust, accurate machine learning tools to aid in the global healthcare crisis precipitated by the pandemic.

Developing New Fully Connected Layers for Convolutional Neural Networks with Hyperparameter Optimization for Improved Multi-Label Image Classification

Chest X-ray evaluation is challenging due to its high demand and the complexity of diagnoses. In this study, we propose an optimized deep learning model for the multi-label classification of chest X-ray images. We leverage pretrained convolutional neural networks (CNNs) such as VGG16, ResNet 50, and DenseNet 121, modifying their output layers and fine-tuning the models. We employ a novel optimization strategy using the Hyperband algorithm to efficiently search the hyperparameter space while adjusting the fully connected layers of the CNNs. The effectiveness of our approach is evaluated on the basis of the Area Under the Receiver Operating Characteristic Curve (AUC-ROC) metric. Our proposed methodology could assist in automated chest radiograph interpretation, offering a valuable tool that can be used by clinicians in the future.

Chest X-ray image classification using transfer learning and hyperparameter customization for lung disease diagnosis

ABSTRACT Lung diseases often result in severe damage to the respiratory tract, and lead to a high risk of mortality within a short period of time. DL models based on ViT are considered to have promising advantages over CNN architectures in terms of computational efficiency, and accuracy when trained on large ImageNet datasets. In this study, we present a new DL approach based on the combination of CNN with ViT to improve the efficiency of pneumonia diagnosis using medical images. In the first stage, raw images are passed through a local filter to capture local relations on the inputs. The local filter block includes two convolutional layers with kernel 3 × 3. This local filtering method aims to enhance rich features before being fed into the patching layer of the ViT block. The proposed method is experimented on the benchmark chest X-ray dataset. The proposed method is evaluated and compared to some well-known models, which include ViT, VGG19, Resnet50, Densnet201. Experimental results demonstrated that the proposed approach based on CNN and ViT reaches higher efficiency with about 1% accuracy to the standard ViT model, and about 2% higher with VGG19, Resnet50, Densnet201 and smaller in model architecture.

Pneumonia Detection In Chest X-Rays Using Neural Networks

Deep learning techniques are widely used to design robust classification models in several areas such as medical diagnosis tasks in which it achieves good performance. In this paper, we have proposed the CNN model (Convolutional Neural Network) for the classification of Chest X-ray images for Radiological Society of North America Pneumonia (RSNA) datasets. The study also tries to achieve the same RSNA benchmark results using the limited computational resources by trying out various approaches to the methodologies that have been implemented in recent years. The proposed method is based on a noncomplex CNN and the use of transfer learning algorithms like Xception, InceptionV3/V4, EfficientNetB7. Along with this, the study also tries to achieve the same RSNA benchmark results using the limited computational resources by trying out various approaches to the methodologies that have been implemented in recent years. The RSNA benchmark MAP score is 0.25 but using the Mask RCNN model (Region Convolutional Neural Network) on a stratified sample of 3017 along with image augmentation gave a MAP (Mean Average Precision) score of 0.15. Meanwhile, the YoloV3 without any hyperparameter tuning gave the MAP score of 0.32 but still, the loss keeps decreasing. Running the model for a greater number of iterations can give better results. Pneumonia is one of the major causes of cancer-related deaths due to its aggressive nature and delayed detections at advanced stages. Early detection of Pneumonia is very important for the survival of an individual, and is a significant challenging problem. Generally, chest radiographs (Xray) and computed tomography (CT) scans are used initially for the diagnosis of the malignant nodules; however, the possible existence of benign nodules leads to erroneous decisions. At early stages, the benign and the malignant nodules show very close resemblance to each other. In this paper, a novel deep learning-based model with multiple strategies is proposed for the precise diagnosis of the malignant nodules. Due to the recent achievements of deep convolutional neural networks (CNN) in image analysis, we have used two deep three-dimensional (3D) customized mixed link network (CMixNet) architectures for lung nodule detection and classification, respectively. Keywords: X-Rays, Deep learning techniques, CNN model, RSNA.

Domain adaptation via Wasserstein distance and discrepancy metric for chest X-ray image classification

Deep learning technology can effectively assist physicians in diagnosing chest radiographs. Conventional domain adaptation methods suffer from inaccurate lesion region localization, large errors in feature extraction, and a large number of model parameters. To address these problems, we propose a novel domain-adaptive method WDDM to achieve abnormal identification of chest radiographic images by combining Wasserstein distance and difference measures. Specifically, our method uses BiFormer as a multi-scale feature extractor to extract deep feature representations of data samples, which focuses more on discriminant features than convolutional neural networks and Swin Transformer. In addition, based on the loss minimization of Wasserstein distance and contrast domain differences, the source domain samples closest to the target domain are selected to achieve similarity and dissimilarity across domains. Experimental results show that compared with the non-transfer method that directly uses the network trained in the source domain to classify the target domain, our method has an average AUC increase of 14.8% and above. In short, our method achieves higher classification accuracy and better generalization performance.

Utilizing Generative Adversarial Network for Synthetic Image Generation to Address Imbalance Challenges in Chest X-Ray Image Classification

Deep learning-based classifiers need lots of image data to train. Unfortunately, not all real-world cases are supported by a huge amount of image data. One of the cases are images for classification of pneumonia infections with chest X-rays images. This study proposes a way of synthesizing chest X-rays with abnormal conditions in order to use the synthesized images for classification purposes. A GAN-based technique can generate synthetic images with greater quality that resemble original images thus can provide a more balanced data distribution than other approaches. To indirectly evaluate the quality of our GAN-based synthetic images, we used CNN-based classification architectures on diverse datasets. Three scenarios examined the effects of synthetic picture categorization. Scenario-1: adding 90% of synthesized images to the original images into the training dataset. Scenario-2: adding 50% of synthesized images to the original images. Scenario-3: adding 10% of synthesized image to the original images. The classification test revealed significantly increased F1 scores in all scenarios. Our study also emphasizes the significance of addressing the problem of imbalanced collections of chest X-ray images and the capability of GANs to alleviate this issue.

Application of Lung Diseases Detection based on CSLNet

Lung diseases caused by fungal or bacterial infections can lead to inflammation in lung and even death when not detected early. A standard method for diagnosing lung diseases is the use of chest X-ray, which require careful examination of X-ray images by a radiology expert. Therefore, this study proposes several new architecture models, namely CSLNet, to classify chest X-ray images for diagnosing whether patients suffer from COVID-19, viral pneumonia, bacterial pneumonia, tuberculosis, and normal. The experimental results show that the model has an 0.99 average Accuracy, 0.98 Precision, 0.98 Recall, and 0.98 f1-score. Meanwhile, the Receiver Operating Characteristic (ROC) for bacterial pneumonia, COVID-19, normal, tuberculosis, and viral pneumonia are 0.97, 0.99, 0.99, 0.94, and 0.97 respectively. This study is based on a deep learning with a new model, CSLNet, which can work well on the dataset of chest X-ray images used for diagnosing lung diseases.

MobileNet Classifier for Detecting Chest X-Ray Images of COVID-19 based on Convolutional Neural Network

Since the COVID-19 pandemic occurred all over the world, numerous studies were carried out to overcome this problem, including COVID-19 image analysis. An expert analysis based on the Chest X-ray images of COVID-19 determines the progression of the lung condition. Eye visualization and expertise of a radiologist have limitations in handling big cases. This study aims to implement the Convolutional Neural Network (CNN) and MobileNet models as deep learning models to classify chest X-ray images into multiclassification, three categories: COVID-19, normal, and virus. The processes were pre-processing and processing. The pre-processing stage was preparing data, and the processing stage was the implementation model and investigating the best model performance in both convolution and classification in depth-wise convolution and batch normalization. The metrics were accuracy, precision, f1-score, and recall. The CNN results of accuracy, precision, recall, and f1-score respectively were 0.94; 0.99; 0.95; and 0.96. The MobileNet results of the metrics were 0.97; 0.98; 0.99, and 0.99. The MobileNet outperforms the CNN results due to depth-wise convolution and batch normalization. Both models contribute to the faster epoch of the best hyperparameter to achieve loss and accuracy convergence. The models are worth recommending to deployment front-end.

Retracted: Multiclass Classification of Chest X-Ray Images for the Prediction of COVID-19 Using Capsule Network.

[This retracts the article DOI: 10.1155/2022/6185013.].

Expert System for Diagnosis of Lung Disease from X-Ray Using CNN and SVM

The lung disease diagnosis expert system utilizes human knowledge to diagnose various conditions affecting the lung. Diseases caused by fungal or bacterial infection in the organ can cause inflammation as well as death when it is not detected on time. A standard method to diagnose these conditions is the use of a chest X-ray (CXR), which requires careful examination of the image by an expert. In this study, several CNN and SVM architectural models were proposed to classify CXR images to diagnose whether a person has COVID-19, Viral Pneumonia, Bacterial Pneumonia, Tuberculosis (TB), and Normal. The experiment showed that InceptionV3 had the best results compared to other CNN architectures and SVM. Classification accuracy, precision, recall, and f1-score of CXR images for COVID-19, Viral Pneumonia, Bacterial Pneumonia, TB, and Normal were 0.86, 0.91, 0.91, and 0.91, respectively. This study was based on a deep learning system with different CNN and SVM architectures that can work well on the CXR images dataset for diagnosing lung disease.

Parallel CNN-ELM: A multiclass classification of chest X-ray images to identify seventeen lung diseases including COVID-19.

Numerous epidemic lung diseases such as COVID-19, tuberculosis (TB), and pneumonia have spread over the world, killing millions of people. Medical specialists have experienced challenges in correctly identifying these diseases due to their subtle differences in Chest X-ray images (CXR). To assist the medical experts, this study proposed a computer-aided lung illness identification method based on the CXR images. For the first time, 17 different forms of lung disorders were considered and the study was divided into six trials with each containing two, two, three, four, fourteen, and seventeen different forms of lung disorders. The proposed framework combined robust feature extraction capabilities of a lightweight parallel convolutional neural network (CNN) with the classification abilities of the extreme learning machine algorithm named CNN-ELM. An optimistic accuracy of 90.92% and an area under the curve (AUC) of 96.93% was achieved when 17 classes were classified side by side. It also accurately identified COVID-19 and TB with 99.37% and 99.98% accuracy, respectively, in 0.996 microseconds for a single image. Additionally, the current results also demonstrated that the framework could outperform the existing state-of-the-art (SOTA) models. On top of that, a secondary conclusion drawn from this study was that the prospective framework retained its effectiveness over a range of real-world environments, including balanced-unbalanced or large-small datasets, large multiclass or simple binary class, and high- or low-resolution images. A prototype Android App was also developed to establish the potential of the framework in real-life implementation.

COVID-19 Diagnosis Based on Multi Deep Neural Networks of Chest Lung X-Ray Images

In this paper, increased attempts are carried out to develop the deep neural networks to diagnose COVID-19 based on Chest X-Ray (CXR). This work introduces a new diagnostic system, utilizing different deep neural networks, InceptionV3, DenseNet121, ResNet50, VGG16 and MobileNetV2 models, to classify CXR images into healthy normal, pneumonia bacterial and COVID-19. Additionally, transfer learning and data augmentation techniques are utilized to solve the problem of scarcity of CXR images; hence the over-fitting of deep models will be avoided. The proposed end-to-end deep system is applied on the dataset sourced from COVID-19 lung CXR images from Kaggle and the IEEE8020 COVID-19 CXR dataset which is introduced by John Hopkins Hospital. The classification results reveal that diagnostic of CXR lung images by InceptionV3 provides the best results, with 98.87% accuracy, 98.88% area under the curve (AUC), 98.98% sensitivity, 98.79% precision, 97.99% F1- score and 1.4574 s computational time. Finally, the ensemble classifier with a voting strategy is proposed to boost the diagnosis performance using the multiple convolutional neural networks (CNNs) instead of one. The classification results are aggregated of each image using the voting technique. It is observed that the performance of the proposed ensemble classifiers with voting strategy reaches the state-of-art performance.

AI-based COVID-19 disease detection in medical images: Advancements and implications in healthcare

<p class="Keywords">Medical image analysis and categorization have seen success using artificial intelligence (AI) approaches and convolutional neural networks (CNNs). The diagnosis of COVID-19 based on the classification of chest X-ray images has been proposed in this research using a deep CNN architecture. Since there was no dataset of chest X-ray pictures that was sufficiently large and of high quality, it was difficult to execute a reliable and accurate CNN classification. The dataset is preprocessed utilizing several stages and procedures to build an acceptable training set for suggested CNN model to reach its optimal performance. This was carried out to address these complications, including the accessibility of a tiny, unbalanced dataset with poor photo quality. The datasets employed in this study included preprocessing processes such as medical image analysis, dataset balance, and data augmentation (DA). The simulation outcomes showed an accuracy of 99.80%, highlighting the strength of presented scheme in the specified application field. The comparative study used in the paper is conducted with a few ML algorithms that demonstrates the outperformance of the suggested scheme in comparison with other schemes in terms of various performance parameters. Additionally, two diagnostic tools, i.e., receiver operating characteristic (ROC) curve and precision-recall curve, that aid in the understanding of probabilistic forecast for binary (two-class) classification predictive modelling issues are also displayed in this article.</p>

Complex network-based classification of radiographic images for COVID-19 diagnosis.

In this work, we present a network-based technique for chest X-ray image classification to help the diagnosis and prognosis of patients with COVID-19. From visual inspection, we perceive that healthy and COVID-19 chest radiographic images present different levels of geometric complexity. Therefore, we apply fractal dimension and quadtree as feature extractors to characterize such differences. Moreover, real-world datasets often present complex patterns, which are hardly handled by only the physical features of the data (such as similarity, distance, or distribution). This issue is addressed by complex networks, which are suitable tools for characterizing data patterns and capturing spatial, topological, and functional relationships in data. Specifically, we propose a new approach combining complexity measures and complex networks to provide a modified high-level classification technique to be applied to COVID-19 chest radiographic image classification. The computational results on the Kaggle COVID-19 Radiography Database show that the proposed method can obtain high classification accuracy on X-ray images, being competitive with state-of-the-art classification techniques. Lastly, a set of network measures is evaluated according to their potential in distinguishing the network classes, which resulted in the choice of communicability measure. We expect that the present work will make significant contributions to machine learning at the semantic level and to combat COVID-19.