The high-accuracy detection of multiple distinct human emotions is crucial for advancing affective computing, mental health diagnostics, and human–computer interaction. The integration of deep learning networks with entropy measures holds significant potential in neuroscience and medicine, especially for analyzing EEG-based emotion states. This study proposes a method combining ResNet18 with differential entropy to identify five types of human emotions (happiness, sadness, fear, disgust, and neutral) from EEG signals. Our approach first calculates the differential entropy of EEG signals to capture the complexity and variability of the emotional states. Then, the ResNet18 network is employed to learn feature representations from the differential entropy measures, which effectively captures the intricate spatiotemporal dynamics inherent in emotional EEG patterns using residual connections. To validate the efficacy of our method, we conducted experiments on the SEED-V dataset, achieving an average accuracy of 95.61%. Our findings demonstrate that the combination of ResNet18 with differential entropy is highly effective in classifying multiple distinct human emotions from EEG signals. This method shows robust generalization and broad applicability, indicating its potential for extension to various pattern recognition tasks across different domains.