In this paper, a novel fractional non-Fourier model is employed to simulate the laser drilling process, addressing limitations inherent in classical heat conduction equations, including the well-known heat equation paradox associated with infinite heat propagation velocity. This model approach combines spatial approximation via the Meshless Local Petrov-Galerkin method with temporal approximation using the Grünwald-Letnikov finite difference scheme. The study assesses the impact of employing fractional orders, both constant and variable over time, on numerical results, and validates the model using experimental data.