Journal Citation Research Articles

Strong Coupling from Inclusive Semi-leptonic Decay of Charmed Mesons

Abstract Employing the heavy quark expansion model with the kinetic scheme, we evaluate αS(mc 2), the strong coupling constant at the charm quark mass mc with data on inclusive semileptonic decays of charmed mesons. Using the experimental values of semileptonic decay widths of the D0 and the D+, the value of αS(mc 2) is determined to be 0.445±0.009±0.114, where the first uncertainty is experimental and the second systematic. This reported αS(mc 2) is in good agreement with the value of αS(mc 2) calculated by running αS(mZ 2) at the Z0 boson mass mZ with the renormalization group evolution equation. In addition, values of αS(mc 2) obtained individually from each of the D0, D+, and D+ s mesons are found to be consistent being of the same origin.Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Impact of selective reporting bias on stroke trials: potential compromise in evidence synthesis - A cross-sectional study

BackgroundAccurate reporting of outcomes is crucial for interpreting the results of randomized controlled trials (RCTs). However, selectively reporting outcomes in publications to achieve researchers’ anticipated results still occurs frequently. This study aims to investigate the prevalence of selective reporting of outcomes in RCTs on treating acute ischemic stroke (AIS), identify factors contributing to this issue, and assess its potential impact on the degree and direction of intervention effect.MethodsA search was conducted in MEDLINE, Embase, and the Cochrane Library to collect interventional RCTs on AIS published from 2020 to 2022. Full texts of RCTs were reviewed, and only those reporting International Clinical Trials Registry Platform primary registry numbers were included. Registration information of the RCTs was extracted from the registry platforms and compared with the publications’ details to assess the selective reporting of outcomes. Bayesian multilevel logistic regression was used to analyze the reasons behind selective reporting.ResultsAmong the total of 159 AIS RCTs identified, 82 (51.6%) were ultimately included, as they reported registration numbers, which encompassed 819 outcomes. Among them, 72 RCTs (87.8%) and 497 outcomes (60.7%) exhibited selective reporting. Omission-type selective reporting (downgrading, omitting, or ambiguously reporting) accounted for 36.4%, while addition-type selective reporting (upgrading, adding, or altering the measurement scope of outcomes) comprised 63.6%. Omission-type selective reporting correlated with negative results (OR: 7.39; 95% CI: 4.08—13.44), whereas addition-type selective reporting correlated with positive results (OR: 2.07; 95% CI: 1.34—3.26) and publication in journals that are not in the top quartile of the Journal Citation Reports (OR: 2.48; 95% CI: 1.15—5.38).ConclusionsRegistered interventional AIS RCTs still face significant issues regarding selective reporting of outcomes. Therefore, it is necessary to further evaluate the influence of selective reporting bias on the positive results obtained from individual AIS RCTs and the systematic reviews based on these RCTs.

Polarization study of the P-wave charmonium radiative decay into a light vector meson at e+e- collider experiment

Abstract In this work, a formalism is presented for the helicity amplitude analysis of the decays ψ(2S) →γ1χcJ, χcJ→γ2V (V=ρ0, Φ, ω) (the subscript 1,2 is used to distinguish the two radiative photons), and the polarization expressions of the P-wave charmonia χcJ and the vector mesons ρ0, Φ, ω for experimental measurements at Electron-Positron Collider. In addition, we derive the formulae of the angular distributions of the χc1,2→γV to extract the degree of transverse polarization PT of e+e- pairs with symmetric beam energy as well as the ratios of two helicity amplitudes x (in χc1 decays) and x, y (in χc2 decays) representing the relative magnitudes of transverse to longitudinal polarization amplitude, and validate it by performing the Monte Carlo simulation. Finally, the statistical sensitivity of PT, x and y are estimated based on the large ψ(2S) data samples collected at the current and proposed future e+e- collider experiment.Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must main tain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Sciences and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd

Probing axion-like particles in leptonic decays of heavy mesons

Abstract We study the possibility to find the axion-like particles (ALPs) through the leptonic decays of heavy mesons. The Standard Model (SM) predictions of the branching ratios of the leptonic decays of heavy mesons are less than corresponding experimental upper limits. This provides some space for the existence of decay channels where the ALP is one of the products. Three scenarios are considered: first, the ALP is only coupled to one single charged fermion, namely, the quark, the antiquark, or the charged lepton; second, the ALP is only coupled to quark and antiquark with the same strength; third, the ALP is coupled to all the charged fermions with the same strength. The constraints of the coupling strength in different scenarios are obtained by comparing the experimental data of the branching ratios of leptonic decays of $B^-$, $D^+$, and $D_s^+$ mesons with the theoretical predictions which are achieved by using the Bethe-Salpeter (BS) method. These constraints are further applied to predict the upper limits of the leptonic decay processes of the $B_c^-$ meson in which the ALP participates.Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Gabapentin for Seizures

What Is the Issue? Gabapentin is 1 of many antiseizure medications available for the treatment of epilepsy in adults; however, there are potential risks associated with its use. Therefore, it is important to determine the place of therapy of gabapentin in the treatment of epilepsy. What Did We Do? To help determine the potential place in therapy for gabapentin in the treatment of epilepsy in adults, we sought to identify and summarize studies of the clinical- and cost-effectiveness of gabapentin as well as recommendations from evidence-based guidelines. We searched key resources, including journal citation databases, and conducted a focused internet search for relevant evidence published since 2014. One reviewer screened articles for inclusion based on predefined criteria, critically appraised the included publications, and narratively summarized the findings. What Did We Find? We identified 1 systematic review and 1 randomized controlled trial (RCT) that evaluated the efficacy of gabapentin in adults with epilepsy. We identified 5 evidence-based guidelines that included recommendations on the use of gabapentin for epilepsy. We did not identify any studies that evaluated its cost-effectiveness. Seizure-free retention at 3 months may be better in adults with epilepsy who were treated with lamotrigine than gabapentin or carbamazepine. There were no differences in other seizure outcomes (such as time to seizure, seizure freedom, or seizure-free retention) for adults with epilepsy treated with gabapentin versus lamotrigine or carbamazepine. Adults with epilepsy treated with gabapentin were more likely to experience fair or poor health perception than those treated with oxcarbazepine. There were no differences in other quality of life outcomes (such as anxiety, depression, or worry about seizures) between those treated with gabapentin versus lamotrigine, carbamazepine, oxcarbazepine, or topiramate. Withdrawals because of adverse events were similar between adults with epilepsy treated with gabapentin and lamotrigine. There were more systemic toxicities in adults treated with gabapentin than carbamazepine or lamotrigine but there were no differences in neurotoxicities between groups. One guideline recommends against the use of gabapentin in people with myoclonic seizures or people with epilepsy with myoclonic-atonic seizures. One guideline states that there is insufficient evidence to consider gabapentin instead of carbamazepine in patients with new-onset focal epilepsy or unclassified generalized tonic-clonic seizures. Three guidelines recommend the use of gabapentin in older adults with epilepsy. One guideline recommends the use of gabapentin in people with intellectual disability and epilepsy, if the benefits outweigh the risks or as a second-line option. What Does It Mean? There were few differences in outcomes between adults with epilepsy treated with gabapentin versus other active comparators in the studies we identified. The included guidelines recommended for or against the use of gabapentin depending on patient factors such as age and type of epilepsy or seizures. Decision-makers may wish to consider individual patient factors such as age and type of epilepsy or seizures as well as the availability of other treatment options when making decisions on the use of gabapentin for the treatment of epilepsy.

$\mathcal{R}^2$ curvature-squared corrections on Langevin diffusion coefficients

Abstract The effect of finite coupling corrections to the Langevin diffusion coefficients on a moving heavy quark in the Super Yang-Mills plasma is investigated. 
These corrections are related to curvature squared corrections in the corresponding gravity sector. 
We compare the results of both longitudinal and perpendicular Langevin diffusion coefficients with those in $\mathcal{N}$=4 Super Yang-Mills plasma. It is observed that the curvature-squared corrections influence the Langevin diffusion coefficients, and the corrections for both Langevin diffusion coefficients demonstrate the dependence on the velocity of the moving heavy quark and the specifics of the higher derivative correction.
In addition, we conduct calculations for the Langevin diffusion coefficients of a moving heavy quark within the Gauss-Bonnet background. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Study of the semileptonic decays Υ(1S) →B(c)lν

Abstract We study the exclusive semileptonic decays $\Upsilon(1S)\to B_{(c)}\ell\bar{\nu}_\ell$, where $\ell = e,\mu,\tau$. The relevant hadronic form factors are calculated using the Covariant Confined Quark Model developed previously by our group. We predict the branching fractions $\mathcal{B}(\Upsilon(1S)\to B_{(c)}\ell\bar{\nu}_\ell)$ to be of the order of $10^{-13}$ and $10^{-10}$ for the case of $B$ and $B_c$, respectively. Our predictions agree well with other theoretical calculations. We also consider the effects of possible New Physics in the case of $\Upsilon(1S)\to B_c\tau\bar{\nu}_\tau$. We show that the branching fraction of this decay can be enhanced by an order of magnitude using constraints from the $B\to D^{(*)}\ell\bar{\nu}_\ell$ and $B_c\to J/\psi\ell \bar{\nu}_\ell$ experimental data.Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Prediction of Energy Resolution in the JUNO Experiment

Abstract This paper presents the energy resolution study in the JUNO experiment, incorporating the latest knowledge acquired during the detector construction phase. The determination of neutrino mass ordering in JUNO requires an exceptional energy resolution better than 3% at 1 MeV. To achieve this ambitious goal, significant efforts have been undertaken in the design and production of the key components of the JUNO detector. Various factors affecting the detection of inverse beta decay signals have an impact on the energy resolution, extending beyond the statistical fluctuations of the detected number of photons, such as the properties of liquid scintillator, performance of photomultiplier tubes, and the energy reconstruction algorithm. To account for these effects, a full JUNO simulation and reconstruction approach is employed. This enables the modeling of all relevant effects and the evaluation of associated inputs to accurately estimate the energy resolution. The study reveals an energy resolution of 2.95% at 1 MeV. Furthermore, the study assesses the contribution of major effects to the overall energy resolution budget. This analysis serves as a reference for interpreting future measurements of energy resolution during JUNO data taking. Moreover, it provides a guideline in comprehending the energy resolution characteristics of liquid scintillator-based detectors. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Bibliometric Analysis of Studies on the Artificial Intelligence in Science Education with VOSviewer

Understanding the trends and developments in artificial intelligence research in science education, which has rapidly advanced in recent years, is crucial for technological innovations and applications in education. Therefore, this study examines research on artificial intelligence in science education conducted between 2019 and 2023 (the last five years) through bibliometric analysis, utilizing the Web of Science database. VOSviewer was used for the analysis. As a result of scanning the Web of Science database under these criteria, 867 studies were identified. Analyzing the distribution of these 867 publications by year reveals a concentration in 2023 and 2022. In terms of publication distribution by country, the leading contributors were the USA, China and Australia. The most prolific authors were identified as D. Gasevic, Z. Xiaoming and S. S. Oyelere. Regarding the number of documents and citations in journals, "Computers & Education" ranked first. The most cited used keywords were "Machine Learning" and "Artificial Intelligence", followed by "Learning Analytics", "Data Science" and "Higher Education". The findings illuminate recent research on artificial intelligence in science education. This study is expected to assist researchers in identifying trends within the field and to provide guidance for future studies.

The Impact of Social Media on Otolaryngology Literature: Analyzing the Correlation Between Altmetrics and Citation Count.

The altmetric attention score (AAS) is an alternative metric that tracks article sharing via online platforms, reflecting an article's online attention trend. The objective of this study was to analyze the impact of social media on Otolaryngology-Head and Neck Surgery (OHNS) literature and analyze the correlation between AAS and citation count. A retrospective review of otolaryngology journal article citation data and Altmetric attention score. The top 10 OHNS journals with highest impact factors were identified using the Journal Citation Reports (JCR). The number of citations in 2018 and 2019 were extracted from JCR and AAS was extracted from the altmetrics website. The primary outcome of this study was to establish whether a correlation between AAS and citation count exists, and whether AAS could serve as a valid alternative metric to assess the quality of individual articles. By analyzing data from 3729 articles, a weak statistically significant positive correlation was identified between AAS and citation count (r = 0.18, P < .001), and between number of citations and Twitter activity (r = 0.18, P < .001). In addition, a statistically significant strong correlation was seen between Twitter activity and AAS (r = 0.79, P < .001). The current results clearly illustrate a weak correlation between AAS and citations and between Twitter activity and citations. Due to various limitations, the use of AAS should be limited to serve as a complementary metric to the current gold standard rather than an alternative metric.

Lenvatinib for the Treatment of Hepatocellular Carcinoma After Liver Transplant

What Is the Issue? Liver transplant is 1 of the main curative therapies for liver cancer; however, hepatocellular carcinoma (HCC) recurrence presents in 10% to 20% of patients after liver transplant. Lenvatinib, an oral multikinase inhibitor drug, was approved for use in Canada as a first-line standard therapy for unresectable HCC, based on a pivotal trial that excluded patients who underwent a prior liver transplant. Data were scarce on the efficacy and safety of lenvatinib for treatment of HCC recurrence in patients who received a liver transplant, and were limited to a few case series and case reports. What Did We Do? We identified and summarized the literature on the evidence of the clinical effectiveness and safety of lenvatinib for the first-line treatment of patients with unresectable HCC recurrence after liver transplant. We searched key resources, including journal citation databases and conducted a focused internet search for relevant evidence published since 2019. One reviewer screened citations for inclusion based on predefined criteria, critically appraised the included studies, and narratively summarized the findings. What Did We Find? We identified a multinational, multicentre, retrospective, single-arm chart review study evaluating the efficacy and safety of lenvatinib in patients with HCC recurrence after liver transplant. Lenvatinib was primarily used as a first-line treatment for most patients (n = 42; 93.3%) and as a second-line treatment for 3 patients (6.7%). The single-arm chart review study showed lenvatinib treatment had an overall response rate (ORR) of 20.0%, a median overall survival of 14.5 months, and a median progression-free survival (PFS) of 7.6 months. These findings were similar to those randomized to lenvatinib in the pivotal phase III REFLECT trial, which excluded patients who had a prior liver transplant. What Does This Mean? The findings of this report suggest that lenvatinib has a potential role as a first-line treatment of patients with HCC recurrence after liver transplant. As the current evidence is limited to a retrospective single-arm chart review study, which had several limitations (e.g., lack of sample size calculation, noncomparative, and retrospective design), further investigations are needed to establish the clinical efficacy and safety of lenvatinib as a first-line treatment for unresectable HCC recurrence after liver transplant.

Jet Tagging with More-Interaction Particle Transformer

Abstract In this study, we introduce the More-Interaction Particle Transformer (MIParT), a novel deep learning neural network designed for jet tagging. This framework incorporates our own design, the More-Interaction Attention (MIA) mechanism, which increases the dimensionality of particle interaction embeddings. We tested MIParT using the top tagging and quark-gluon datasets. Our results show that MIParT not only matches the accuracy and AUC of LorentzNet and a series of Lorentz-equivariant methods, but also significantly outperforms the ParT model in background rejection. Specifically, it improves background rejection by approximately 25\% at a 30\% signal efficiency on the top tagging dataset and by 3\% on the quark-gluon dataset. Additionally, MIParT requires only 30\% of the parameters and 53\% of the computational complexity needed by ParT, proving that high performance can be achieved with reduced model complexity. For very large datasets, we double the dimension of particle embeddings, referring to this variant as MIParT-Large (MIParT-L). We find that MIParT-L can further capitalize on the knowledge from large datasets. From a model pre-trained on the 100M JetClass dataset, the background rejection performance of the fine-tuned MIParT-L improved by 39\% on the top tagging dataset and by 6\% on the quark-gluon dataset, surpassing that of the fine-tuned ParT. Specifically, the background rejection of fine-tuned MIParT-L improved by an additional 2\% compared to the fine-tuned ParT. The results suggest that MIParT has the potential to advance efficiency benchmarks for jet tagging and event identification in particle physics.Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd

Potential to Identify the Neutrino Mass Ordering with Reactor Antineutrinos in JUNO

Abstract The Jiangmen Underground Neutrino Observatory (JUNO) is a multi-purpose neutrino experiment under construction in South of China. This paper presents an updated estimate of JUNO's sensitivity to the neutrino mass ordering using the reactor antineutrinos emitted from eight nuclear reactor cores in the Taishan and Yangjiang nuclear power plants. This measurement is planned by studying the fine interference pattern caused by quasi-vacuum oscillations in the oscillated antineutrino spectrum at a baseline of 52.5~km and is completely independent of the CP violating phase and the neutrino mixing angle θ23. The sensitivity is obtained through a joint analysis of JUNO and TAO detectors utilizing the best available knowledge to date about the location and overburden of the JUNO experimental site, the local and global nuclear reactors, the JUNO and TAO detectors responses, the expected event rates and spectra of signal and backgrounds, and the systematic uncertainties of the analysis inputs. It is found that a 3σ median sensitivity to reject the wrong mass ordering hypothesis can be reached with an exposure of about 6.5 years × 26.6~GW thermal power.Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd.

Short-Cycle Autoclave Sterilization of Instruments in Same-Day Ophthalmic Surgeries

What Is the Issue? The volume of ophthalmic surgeries is increasingly high, with cataract surgery being 1 of the most performed surgeries in Canada. Infections following ophthalmic surgeries, while rare, can cause severe complications that may lead to irreversible vision loss. Reducing postsurgery infections is a high priority in clinical practice. Running a full wrapped, terminal steam sterilization cycle for ophthalmic instruments in autoclaves may be inefficient for ophthalmic surgeries and may cause unnecessary heavy economic and environmental burdens due to high surgical volumes. Using instruments sterilized on a short cycle between sequential same-day ophthalmic surgeries may help improve efficiency and reduce resources used. These instruments are generally processed using autoclaves (i.e., steam sterilizers); the effectiveness of a shorter-cycle method of sterilization is unclear. What Did We Do? To inform decisions regarding the use of autoclaves for short-cycle sterilization for sequential same-day instrument use in ophthalmic surgery, we sought to identify and summarize evidence comparing this method to full-cycle sterilization of wrapped instruments and identify any relevant recommendations. We searched key resources, including journal citation databases, and conducted a focused internet search for relevant evidence published since 2012. One reviewer screened articles for inclusion based on predefined criteria. What Did We Find? In a laboratory setting to simulate sequential same-day procedures, short-cycle sterilization with interrupted dry time for unwrapped ophthalmic instruments is feasibly as effective as full-cycle sterilization for wrapped instruments using the STATIM autoclave. Similarly, short-cycle sterilization with interrupted dry time for contained ophthalmic instruments is feasibly as effective as full-cycle sterilization for contained instruments using the AMSCO autoclave. For sequential same-day ophthalmic procedures, wet instruments sterilized by a short-cycle process with an interrupted dry time can remain sterile for at least 3 minutes if kept in a covered sterilizer containment device. One guideline recommends that wrapped or unwrapped ophthalmic instruments sterilized by a short-cycle process without full drying should be stored in a covered containment device until retrieved by staff wearing sterile gloves and gowns in the operating room for the subsequent surgery after a short delay. Phaco handpieces should be immediately primed with a balanced salt solution and remain wet as they sit on the sterile instrument table. We did not identify any clinical setting evidence from studies or autoclave manufacturers. It is unclear if clinical outcomes differ between patients undergoing sequential same-day ophthalmic surgeries using short-cycle sterilized instruments and those undergoing surgery using full-cycle sterilized instruments. What Does This Mean? Preliminary laboratory evidence and guideline recommendations supporting the use of autoclaves for short-cycle sterilization of instruments for sequential same-day ophthalmic surgeries are available. However, there is no clinical effectiveness evidence available on this process in patient settings. Future research is necessary to understand the clinical safety of using instruments sterilized by short cycles for sequential same-day use for patients undergoing ophthalmic surgeries. In addition to the evidence and recommendations identified, other factors, such as environmental influence, may be useful considerations when making decisions about short-cycle sterilization for sequential same-day instrument use for ophthalmic surgery.

Essential Reads in Rhinology: A Bibliometric Analysis

Abstract Aims Rhinology is a progressive subspecialty within otolaryngology. Bibliometric analysis is a powerful method to survey the landscape of literature on a specific topic and identify publication trends. We aimed to analyze the 50 most impactful English-language rhinology manuscripts of all time to create a targeted reading list for otolaryngologists. Material and Methods The Journal Citation Report within the Web of Science database was utilized to identify articles relating to rhinology. Web of Science Research categories were restricted to otolaryngology. The articles were then ranked by number of citations. The top 50 articles of all time ranked by number of citations were analyzed. The articles were analyzed for publication year, journal impact factor, citation density, first author (FA), and senior author (SA) name, country, and institution. Statistical analyses were performed. Results Most articles were published in the 2000s (N = 22, 44%) and 1990s (N = 11, 22%). Male FA (N = 37, 74%) and SA (N = 43, 86%) published most articles. Most articles were clinical studies (N = 36, 72%) followed by clinical guidelines/expert opinions. Most articles were published in the United States (N = 28, 56%) and England (N = 9, 18%). There were more female FAs of guidelines/position papers than basic lab, reviews, and clinical studies. England had more female FAs than other countries, and the United States had more female SA. There was an average of 585.2 citations per study. Conclusion This investigation highlights the most influential literature within rhinology. The most impactful studies are consensus statements, large multicenter studies, and technique studies. Significant gender disparities in authorship exist.

Endometriosis and Infertility: A Bibliometric Analysis of the 100 Most-Cited Articles from 2000 to 2023

Objectives: This study aimed to conduct a bibliometric analysis of research on endometriosis and infertility, focusing on the 100 most-cited (TOP100) articles in the literature. Design: The design of this study is a bibliometric analysis. Participants/Materials, Setting, Methods: The SCOPUS database was searched using the terms “endometriosis” and “infertility.” The productivity and impact of research publications by authors, countries, and journals were assessed using the following indicators: total number of publications, total number of citations (TNC), journal impact factor, and journal citation indicator. The bibliometric analysis was conducted from January 1, 2000, to December 31, 2023, using IBM SPSS™ for Windows and VOSviewer 1.6.20. VOSviewer was used to evaluate the TNC, total number of authors/coauthors, and collaboration network between countries of the TOP100 articles. VOSviewer was also used to create keyword co-occurrence networks. Results: Of the TOP100 articles, 69 were literature review articles, with a mean of 448.97 ± 513.5 citations (range: 191–2,705). The TOP100 articles were published by 479 authors (mean 5.8 ± 7.3 per study) from 40 countries in 39 high-impact journals. The keyword co-occurrence network revealed a grouping of four clusters, with terms related to pathophysiology, clinical management, assisted reproductive technology, and hormonal treatment of endometriosis. Limitations: The main limitation of our study is the use of only one database and TNC as the main bibliometric indicator. Studies need at least 2–3 years after publication to accumulate sufficient citations for bibliometric indicators to be reliable. This means that large number of recent studies were not included in this bibliometric analysis. Conclusions: This study revealed trends in endometriosis and infertility research, especially in the fields of immunology and genetics. It also highlights the importance of global collaboration to improve diagnostics, treatments, and outcomes.

Supersymmetric Hybrid Inflation in Light of CMB Experiments and Swampland Conjectures

Abstract In this study, we revisited supersymmetric (SUSY) hybrid inflation considering the latest observations from CMB experiments and the swampland conjectures. We demonstrated that when incorporating radiative, soft mass, and SUGRA corrections to the scalar potential, SUSY hybrid inflation remains consistent with Planck 2018 data. It is commonly perceived that SUSY hybrid inflation with a minimal K"ahler potential results in a gauge symmetry breaking scale $M$ of ${\cal O}(10^{15})$ GeV, leading to issues with the proton decay rate. Our analysis introduces a new parameter space where the proton decay problem is mitigated by achieving $M \sim 10^{16}$ GeV with $M_{S}^{2}&lt;0$ and $am_{3/2}&gt;0$. This scenario necessitates a soft SUSY breaking scale $|M_{S}| \gtrsim 10^{6}$ GeV. Furthermore, we found that the tensor-to-scalar ratio $r$ spans from $10^{-16}$ to $10^{-6}$, indicating a very small value. This small ratio allows the modified swampland criteria to hold, although satisfying the trans-Planckian censorship conjecture remains challenging. To address this, we also explored non-minimal K"ahler potentials. By fixing the spectral index at $n_{S}=0.9665$, consistent with the central value of Planck 2018 data, and setting $M=2\times 10^{16}$ GeV, we presented our calculations. We showed that the canonical measure of primordial gravitational waves, $r$, for $M_{S}=$ 1 TeV, $m_{3/2}=$ 1 TeV, $\kappa_{S}&lt;0$ for $\cal{N}=$1 and $\cal{N}=$2, ranges from $10^{-5}$ to $0.01$, making it detectable by Planck and upcoming experiments such as LiteBIRD, Simons Observatory, PRISM, PIXIE, CORE, CMB-S4, and CMB-HD. Additionally, we outlined the parametric space and provided benchmark points for the non-minimal case, ensuring compatibility with both the modified swampland and trans-Planckian censorship conjectures. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Article funded by SCOAP3 and published under licence by Chinese Physical Society and the Institute of High Energy Physics of the Chinese Academy of Science and the Institute of Modern Physics of the Chinese Academy of Sciences and IOP Publishing Ltd

Continuous Diffused Oxygen Therapy for Wound Healing

What Is the Issue? Wounds are prevalent across health care settings, costing Canada an estimated $12 billion per year in wound care. Chronic wounds (wounds that do not heal in the typical amount of time, which can depend on the size and type of wound) can have a significant impact on a patient’s quality of life and health. Healing tissue has a high need for oxygen. Oxygen can be delivered in several ways, including topical oxygen therapy, which delivers oxygen directly to the wound. One type of topical oxygen therapy is continuously diffused oxygen (CDO) therapy, which uses a device that takes oxygen from the air and then delivers pure, humidified oxygen to the wound. We previously completed a Rapid Review on CDO therapy for wounds in 2020. This review aimed to determine if new evidence has since been published on this topic. What Did We Do? To inform decisions about CDO therapy for wound healing, we sought to identify and summarize literature comparing the clinical effectiveness and cost-effectiveness of CDO therapy versus conventional wound care. We also attempted to identify evidence-based recommendations for the use of CDO therapy. We searched key resources, including journal citation databases, and conducted a focused internet search for relevant evidence published since 2019. One reviewer screened articles for inclusion based on predefined criteria, critically appraised the included studies, and narratively summarized the findings. What Did We Find? CDO therapy appears to be clinically effective for treating patients with diabetic foot ulcers, particularly chronic or hard-to-heal ulcers that have not responded to standard care. Rates of adverse events were comparable between patients receiving CDO and patients receiving standard care. Two cost-effectiveness studies reported that CDO is likely to be cost-effective compared to standard care for patients with chronic, hard-to-heal diabetic foot ulcers. We identified fewer studies for other types of wounds. Preliminary evidence suggests that CDO therapy may be helpful for patients with other types of wounds that are chronic or have not responded to standard care. Reporting on adverse events was limited. Limited evidence suggests that patients receiving CDO therapy had better outcomes if their wound was debrided more frequently as well as if they received CDO therapy for a longer time. The evidence-based guidelines recommend the use of topical oxygen therapy (of which CDO is a subtype) for treating diabetic foot ulcers that have failed to heal with standard care. One guideline suggested that topical oxygen therapy may be considered for other types of non-neoplastic, hard-to-heal wounds. We did not find cost-effectiveness evidence for wounds other than diabetic foot ulcers that met the inclusion criteria for our report. We also did not identify any clinical effectiveness or cost-effectiveness evidence, or any guidelines regarding the use of CDO to treat First Nations, Inuit, and Métis patients, that met the inclusion criteria for our report. What Does This Mean? CDO therapy may be beneficial and more cost-effective than standard care for patients with hard-to-heal, chronic diabetic foot ulcers that have not responded to standard care. Evidence-based guidelines also recommend the use of CDO therapy for this patient population. The clinical effectiveness and cost-effectiveness of CDO therapy for other types of wounds is still unclear. It is also unclear if there is an optimal way to provide CDO (e.g., oxygen flow rate, debridement, length of treatment). We identified limited evidence that reported on patient ethnicity. Considering that some groups, including First Nations, Inuit, and Métis Peoples, have higher rates of diabetes than the overall population in Canada — which may lead to higher rates of diabetic foot ulcers — decision-makers involved in implementing CDO therapy should consider ways to ensure equitable access for all patients who may need this treatment.

Trends and insights in animal and biomedical research: A 5-year scientometric analysis of orthodontic peer-reviewed journals

Biomedical research plays a critical role in advancing orthodontic innovations by identifying new targets for therapeutic interventions and developing more effective, personalized orthodontic treatment. This study evaluates the major contributors and trends in animal-related orthodontic research over the past 5 years (2017-2023). All animal-related studies published in the eight orthodontic journals listed in the 2022 Journal Citation Reports between January 2017 and June 2023 were retrieved from the Web of Science Core Collection. After examination, the following bibliometric data were extracted from each article: title, authors, affiliations, geographic origin, year of publication, journal name, and keywords. Multiple bibliometric software packages including Biblioshiny R-package software, Datawrapper, and Datasmith were used to analyze different bibliometric outcomes. A total of 3669 articles were screened from which 266 were selected and included in the analysis. The annual growth rate of production exhibited a decline of 11.18%. Most of the included studies focused on orthodontic tooth movement (32.3%), mainly utilizing rat models (50%). Although the United States accounted for the highest number of publications (n = 236), the trend in funded research showed a decreasing trajectory over time, with notably limited funding from the National Institutes of Health. This study reveals a declining trend in overall animal-related orthodontic research, highlighted by a significant decrease in National Institutes of Health funding over time. To address this gap, academic institutions and professional organizations should support initiatives fostering biomedical orthodontic research.

Journal Metrics of the Journal of Craniofacial Surgery: An Analysis Based on the Journal Citation Report 2024.

This study aims the analysis of the journal metrics of Journal of Craniofacial Surgery based on 2024 Journal Citation Reports (JCR) data. In the Journal Citation Reports 2024, shared by Clarivate Analytics on June 20, 2024, the journal metrics of the Journal of Craniofacial Surgery were examined in detail. According to the reports published by Clarivate Analytics in 2024, the journal's impact factor in 2023 was determined as 1.0 and the impact factor excluding self-citations was calculated as 0.8. These values show that the impact factor of the journal has increased in recent years. Also, it is seen that the Journal of Craniofacial Surgery, which has been in the fourth quartile (Q4) among the journals in the "Surgery" category for the last 10 years, has risen to the third quartile (Q3) this year. The increase in the impact factor and ranking of the Journal of Craniofacial Surgery shows that the journal has strengthened its position in the scientific field and is moving toward higher levels. However, it is suggested that other metrics should be taken into consideration in addition to the impact factor.