Ciba Foundation Symposium Research Articles

Book Reviews

Journal Article Book Reviews Get access Maternal Recognition of Pregnancy Ciba Foundation. Amsterdam: Excerpta Medica, 1979. (Ciba Foundation symposium, n.s. no. 64.) 432 pages; figures; tables. 25 × 17 cm. £28.08 R E D R E D Search for other works by this author on: Oxford Academic PubMed Google Scholar British Medical Bulletin, Volume 35, Issue 2, May 1979, Page 208, https://doi.org/10.1093/oxfordjournals.bmb.a071574 Published: 01 May 1979

Book Reviews

Book Reviews

Book Reviews

Journal Article Book Reviews Get access Chlorophyll Organisation and Energy Transfer in Photosynthesis. Excerpta Medica (1979) CIBA Foundation Symposium 61 (new series). Pp. 388, 104 figs. 22 tables, US$ 38.25 D 86.00. W. P. WILLIAMS W. P. WILLIAMS Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Experimental Botany, Volume 30, Issue 6, December 1979, Pages 1287–1288, https://doi.org/10.1093/jxb/30.6.1287 Published: 01 December 1979

BOOK REVIEWS

Book review in this article: The Freezing of Mammalian Embryos. Ciba Foundation Symposium 52 (new series). Edited by K. Elliott and J. Whelan. The IUD—A Practical Guide. Edited by R. Snowdon, M. Williams and D. Hawkins. Current Developments in Perinatology. The fetus, placenta, and newborn. Edited by Frederick P. Zuspan. Documenta Geigy. Leading Symptoms: Laboratory Values Selected Chapters on carbohydrate, nitrogen and metal metabolism. By C. Leitner and M. Eggstein.

Reply to Lister

C. Lister (EOS, 59(2), 66, 1978) has suggested that we solve literature dissemination problems by abstract publication keyed to microfiche documents. This idea sounds logical but rests upon a questionable assumption, namely, that the exclusive or main function of scientific literature is to inform. In fact, D. Price (Ciba Foundation Symposium on Communication in Science: Documentation and Automation, 1966) has suggested that information dissemination makes up only 20% of the function of publication. The other 80% may include services such as justifying the work of individuals and organizations, providing scientific credentials, serving as criteria for pay increases and advancement, boosting egos, and perhaps even fulfilling artistic aspirations (who is fulfilled by microfiche?).

Health Care in a Changing Setting: the UK Experience. Ciba Foundation Symposium 43 (new series). (Pp. 188; illustrated; $14.25.) Excerpta Medica: Amsterdam. 1976. - Health and Industrial Growth. Ciba Foundation Symposium 32 (new series). (Pp. 267; illustrated; $16.95.) Excerpta Medica: Amsterdam. 1975.

Health Care in a Changing Setting: the UK Experience. Ciba Foundation Symposium 43 (new series). (Pp. 188; illustrated; $14.25.) Excerpta Medica: Amsterdam. 1976. - Health and Industrial Growth. Ciba Foundation Symposium 32 (new series). (Pp. 267; illustrated; $16.95.) Excerpta Medica: Amsterdam. 1975.

Book Reviews

Journal of Paediatrics and Child HealthVolume 14, Issue 2 p. 131-135 Book Reviews First published: June 1978 https://doi.org/10.1111/j.1440-1754.1978.tb02962.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Book reviewed in this article: HEADACHE — ITS CAUSES AND TREATMENT. By James W. Lance; 1977 RECENT RESULTS IN CANCER RESEARCH — CANCER CHEMOTHERAPY. Edited by A. Clarysse, Y. Kenis and G. Mathe; 1976 PAEDIATRIC PSYCHOPHARMACOLOGY. By James H. White; 1977 CHILD DEVELOPMENT. Edited by Stewart Cohen and Thomas J. Comiskey; 1977 CURRENT PROBLEMS IN PEDIATRIC HEMATOLOGY. Edited by Frank A. Oski, Ernst R. Jaffe and Peter A. Miescher; 1975 PLAY. By Catherine Garvey; 1977 BORN TOO SOON OR BORN TOO SMALL. By G. A. Neligan, I. Kolvin, D. Mcl. Scott and R. F. Garside; 1976 DISTRESS AND COMFORT. By Judy Dunn; 1977 BREAST-FEEDING AND THE MOTHER. Edited by Ciba Foundation Symposium 45 (New Series); 1976 DEVELOPMENTAL PAEDIATRICS: PERSPECTIVES AND PRACTICE. By K. S. Holt; 1977 PEDIATRICS, 16th Edition. Edited by Abraham M. Rudolph; 1977 Volume14, Issue2June 1978Pages 131-135 RelatedInformation

BOOK REVIEWS

Book review in this ArticleA Colour Atlas of Histological Staining Techniques. By A. Smith and J. Bruton.Immunology of the Gut. Ciba Foundation Symposium 46 (New Series). Ed. By Ruth Porter and Julie Knight.Atlas of Cell Biology. By J. C. Roland, A. SzÖllÖsi and D. SzÖllÖsi.

Synthetic immunoregulating molecules: A potential bridge between cytostatic chemotherapy and immunotherapy of cancer

The concept of immunomodulation as an adjunct to cancer therapy is based on ample evidence that a variety of agents augment the immune reaction to unrelated antigens in experimental animals and increase their resistance to tumors. The ever-growing list of such agents includes viruses, bacteria, fungi, and their products (Ciba Foundation Symposium, 1973). Following the pioneering work of Math6 with BCG (Math~, 1971), investigators have been very active in this field in recent years (Chedid et al., 1973; Lamensans et al., 1975; Lamoureux et al., 1976; Laucius et al., 1974; Leclerc et al., 1976; Mastrangelo et al., 1976; Old et al., 1959; Weiss et al., 1961; Zbar et al., 1970). Most, if not all of these studies, have been done with viable or killed microorganisms (Hersch et al., 1976; Israel, 1976; Pouillart et al., 1976), cell walls (Chedid et al., 1973; Gray et al., 1975; Yamamura et al., 1976a; Zbar et al., 1972), or very complex fractions such as raethanol extract residue (MER) (Perloff et al., 1977; Yron et al., 1973) or interphase material (IPM) (Lamensans et al., 1975). Some organisms such as BCG and Corynebacterium parvum have been shown to be dramatically effective in certain experimental models, but investigators are well aware of the fact that they contain a great variety of heterogenous antigens, some of which might cross-react with host tissues (Borsos and Rapp, 1973; Bucana and Hanna, 1974; Vandenbark et al., 1975). They are also endowed with undesirable pharmacologic side effects (Werner et al., 1977). Consequently, current attempts at isolating chemically well-defined fractions from whole bacteria have been given a high priority, with the justification that they may lead to preparations that retain important therapeutic effects but with diminished or no toxicity.

BOOK REVIEWS

Book reviews in this article: Clinics in Obstetrics and Gynaecology. Edited by C. R. Whitfield. Current Trends in the Management of Breast Cancer. Edited by R. Robinson Baker. Sex and Infertility. Edited by R. G. Harrison and C. H. de Boer. The Fetus and Birth. Ciba Foundation Symposium 47 (new series). Female Urinary Incontinence. By S. L. Stanton. Therapeutic Problems in Pregnancy. Edited by P. J. Lewis. Atlas of Colposcopy. By Per Kolstad and Adolf Stafl. Perinatal Intensive Care. Edited by Silvio Aladjem and Audrey K. Brown.

Book Review: Outcome of Severe Damage to the Central Nervous System (Ciba Foundation Symposium No. 34)

Book Review: Outcome of Severe Damage to the Central Nervous System (Ciba Foundation Symposium No. 34)

Medical Research Systems in Europe. Ciba Foundation Symposium 21 (new series). (Pp. 335; illustrated; $16.50.) Excerpta Medica: Amsterdam, 1973. - Research and Medical Practice: their Interaction. Ciba Foundation Symposium 44 (new series). (Pp. 220; illustrated; $16.25.) Excerpta Medica: Amsterdam. 1976.

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The Frank—Starling Curve

A basic property of the normal heart is that if its volume is increased, there is an increase in the strength of the contraction. The phenomenon is known as Starling's Law, and as the FrankStarling mechanism. This phenomenon is of great importance. If the heart were unable to increase its output when distended, the distension would become progressively severe. The underlying important relation in the ventri: cular muscle is that between systolic contractile force and muscle (or sarcomere) length: the lengthtension curve (Ciba Foundation Symposium, 1974). An example is shown in Fig. 1. A length of heart muscle is stimulated to contract but is not allowed to shorten. It therefore develops force isometrically. This is repeated for a range of different muscle lengths. Systolic contractile force (nor­ malized for the cross-sectional area of muscle giving stress) is plotted against length as a

Book Reviews

Book reviewed in this article:G. F. Fraser: The causes of profound deafness in childhood. A study of 3 535 individuals with severe hearing loss present at birth or of childhood onsetK. Elliott & J. Knight (eds.): Acute diarrhoea in childhood, Ciba Foundation Symposium 42. Elsevier Excerpta Medica North‐Holland, Amsterdam 1976D. S. McLaren (ed.): Nutrition in the communityZ. Laron (ed.): The adipose child, vol. 1, 227 pp., illus. In Z. Laron & Z. Dickerman (eds.): Pediatric and adolescent endocrinology.F. H. Stone: Psychiatry and the paediatrician

Ciba Foundation Symposium No. 48 (New Series): Purine and Pyrimidine Metabolism

Ciba Foundation Symposium No. 48 (New Series): Purine and Pyrimidine Metabolism

Regional variation of lamb blood vessel responsiveness to vasoactive agents during fetal development.

HomeCirculation ResearchVol. 41, No. 6Regional variation of lamb blood vessel responsiveness to vasoactive agents during fetal development. Free AccessAbstractPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessAbstractPDF/EPUBRegional variation of lamb blood vessel responsiveness to vasoactive agents during fetal development. C Su, J A Bevan, N S Assali and C R Brinkman3rd C SuC Su Search for more papers by this author , J A BevanJ A Bevan Search for more papers by this author , N S AssaliN S Assali Search for more papers by this author and C R Brinkman3rdC R Brinkman3rd Search for more papers by this author Originally published1 Dec 1977https://doi.org/10.1161/01.RES.41.6.844Circulation Research. 1977;41:844–848 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Müller J, Schwab M, Rosenfeld C, Antonow-Schlorke I, Nathanielsz P, Rakers F, Schubert H, Witte O and Rupprecht S (2017) Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation, Journal of Vascular Research, 10.1159/000477629, 54:5, (259-271), . Eiby Y, Shrimpton N, Wright I, Lumbers E, Colditz P, Duncombe G and Lingwood B (2016) Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets, Pediatric Research, 10.1038/pr.2016.156, 80:6, (870-879), Online publication date: 1-Dec-2016. Pearce W (2014) The Fetal Cerebral Circulation: Three Decades of Exploration by the LLU Center for Perinatal Biology Advances in Fetal and Neonatal Physiology, 10.1007/978-1-4939-1031-1_16, (177-191), . Eiby Y, Lumbers E, Staunton M, Wright L, Colditz P, Wright I and Lingwood B (2014) Endogenous angiotensins and catecholamines do not reduce skin blood flow or prevent hypotension in preterm piglets, Physiological Reports, 10.14814/phy2.12245, 2:12, (e12245), Online publication date: 1-Dec-2014. Tzao C, Nickerson P, Russell J, Noble B and Steinhorn R (2003) Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study, Histochemistry and Cell Biology, 10.1007/s00418-002-0494-z, 119:2, (125-130), Online publication date: 1-Feb-2003. Harris A, Robinson R, Koehler R, Traystman R and Gleason C (2001) Blood-brain barrier permeability during dopamine-induced hypertension in fetal sheep, Journal of Applied Physiology, 10.1152/jappl.2001.91.1.123, 91:1, (123-129), Online publication date: 1-Jul-2001. Au-Fliegner M, Salami S and Gosche J (1998) Pulmonary arterioles from rats with congenital diaphragmatic hernias are hypoplastic but not hyperresponsive, Journal of Pediatric Surgery, 10.1016/S0022-3468(98)90009-4, 33:9, (1366-1370), Online publication date: 1-Sep-1998. Harris A, Helou S, Traystman R, Jones M and Koehler R (1998) Efficacy of the Cushing Response in Maintaining Cerebral Blood Flow in Premature and Near-Term Fetal Sheep, Pediatric Research, 10.1203/00006450-199801000-00008, 43:1, (50-56), Online publication date: 1-Jan-1998. Liu S, Hislop A, Haworth S and Barnes P (2012) Developmental changes in endothelium-dependent pulmonary vasodilatation in pigs, British Journal of Pharmacology, 10.1111/j.1476-5381.1992.tb14335.x, 106:2, (324-330), Online publication date: 1-Jun-1992. Shaul P, Magness R, Muntz K, DeBeltz D and Buja L (1990) Alpha 1-adrenergic receptors in pulmonary and systemic vascular smooth muscle. Alterations with development and pregnancy., Circulation Research, 67:5, (1193-1200), Online publication date: 1-Nov-1990.Harris A, Koehler R, Gleason C, Jones M and Traystman R (1989) Cerebral and peripheral circulatory responses to intracranial hypertension in fetal sheep., Circulation Research, 64:5, (991-1000), Online publication date: 1-May-1989. Buckley N (1986) Maturation of circulatory system in three mammalian models of human development, Comparative Biochemistry and Physiology Part A: Physiology, 10.1016/0300-9629(86)90080-0, 83:1, (1-7), Online publication date: 1-Jan-1986. Tibboel D, Gaillard J and Molennar J (1986) The importance of mesenteric vascular insufficiency in meconium peritonitis, Human Pathology, 10.1016/S0046-8177(86)80466-X, 17:4, (411-416), Online publication date: 1-Apr-1986. Walker A (1984) Physiological Control of the Fetal Cardiovascular System Fetal Physiology and Medicine, 10.1016/B978-0-407-00366-8.50015-0, (287-316), . Mott J and Walker D (1983) Neural and Endocrine Regulation of Circulation in the Fetus and Newborn Comprehensive Physiology, 10.1002/cphy.cp020323, (837-883), Online publication date: 1-Dec-1983. Yokoyama M, Akita H, Mizutani T, Fukuzaki H and Watanabe Y (1983) Hyperreactivity of coronary arterial smooth muscles in response to ergonovine from rabbits with hereditary hyperlipidemia., Circulation Research, 53:1, (63-71), Online publication date: 1-Jul-1983.Robillard J, Gomez R, Meernik J, Kuehl W and VanOrden D (1982) Role of angiotensin II on the adrenal and vascular responses to hemorrhage during development in fetal lambs., Circulation Research, 50:5, (645-650), Online publication date: 1-May-1982. Bevan J and Bevan R (2008) Developmental Influences on Vascular Structure and Function Ciba Foundation Symposium 83 - Development of the Autonomic Nervous System, 10.1002/9780470720653.ch5, (94-107) Fleisch J (1980) Age-related changes in the sensitivity of blood vessels to drugs, Pharmacology & Therapeutics, 10.1016/0163-7258(80)90055-8, 8:2, (477-487), Online publication date: 1-Jan-1980. December 1, 1977Vol 41, Issue 6 Advertisement Article InformationMetrics Copyright © 1977 by American Heart Associationhttps://doi.org/10.1161/01.RES.41.6.844 Originally publishedDecember 1, 1977 PDF download Advertisement

Breast Feeding and the Mother. CIBA Foundation Symposium 45. Pp. 300. (Associated Scientific Publishers, Amsterdam, 1977.)

Breast Feeding and the Mother. CIBA Foundation Symposium 45. Pp. 300. (Associated Scientific Publishers, Amsterdam, 1977.)

Lung Liquids. Ciba Foundation Symposium 38 (new series).

Lung Liquids. Ciba Foundation Symposium 38 (new series).

Book Reviews

Book reviewed in this article:BIRTH WITHOUT VIOLENCE. By Frederick LeboyerPARENT‐INFANT INTERACTION. Ciba Foundation Symposium 33PEDIATRIC CLINICAL GASTROENTEROLOGY. By C. C. Roy, A. Silverman and F. J. CozzettoEVALUATION OF FAMILY PLANNING IN HEALTH SERVICES. Report of a WHO expert committeePEDIATRIC OPHTHALMOLOGY. Edited by Robinson D. Harley, M.D., Ph.D., F.A.C.S.NEUROLOGIC INFECTIONS IN CHILDREN. (Volume XII in the series Major Problems in Paediatrics.) By W. E. Bell and W. F. McCormickPEDIATRIC SCREENING TESTS. Edited by William K. Frankenburg and Bonnie W. CampTHE TRADITIONAL BIRTH ATTENDANT IN MATERNAL AND CHILD HEALTH AND FAMILY PLANNING. A guide to her training and utilization. World Health Organization; 1975. Maria De Lourdes Verderese and Lily M. Turnbull

Ciba Foundation Symposium no. 29 Cell Patterning

FEBS LettersVolume 70, Issue 1-2 p. 282-283 Book reviewFree Access Ciba Foundation Symposium no. 29 Cell Patterning Edited by Ruth Porter and J. Rivers Elsevier/Excerpta Medica/North-Holland; Amsterdam, Oxford, New York, 1975 viii + 356 pages. Dfl. 62.50, $26.95 P.M. Clissold, P.M. ClissoldSearch for more papers by this author P.M. Clissold, P.M. ClissoldSearch for more papers by this author First published: November 01, 1976 https://doi.org/10.1016/0014-5793(76)80777-6AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume70, Issue1-2November 01, 1976Pages 282-283 RelatedInformation