Chronic Polyarthritis Research Articles

A comparison of plasma 17-hydroxycorticosteroid levels with the urinary excretion of 17-ketogenic steroids and 17-ketosteroids.

ABSTRACT Plasma 17-OHCS and urinary excretion of 17-KGS and 17-KS have been compared in 24 patients with chronic polyarthritis, who had been treated for years with corticosteroids. All medication was discontinued 3 days before this investigation. To test the adrenal cortical response the patients were given intramuscular injections of 40 IU of a long-acting ACTH preparation twice daily on 6 consecutive days. Plasma 17-OHCS were determined at 8 a. m. before the first ACTH injection and 3 hours after the injection on the first and sixth treatment days. The urinary concentration of 17-KGS and 17-KS were measured in 24 hour samples on the control day, and on the first and sixth days of treatment. The results show a greater variation in the 17-KS groups than in the 17-KGS and 17-OHCS groups, the smallest variation being in the 17-OHCS groups. There is a significant increase in all values after the first ACTH injection and a further significant increase after the sixth injection, but the t-values are much larger in the 17-OHCS groups than in the 17-KS groups, while the 17-KGS groups occupy an intermediate position. The plasma 17-OHCS values correlate better with the urinary 17-KGS than with the 17-KS. The correlation between 17-OHCS and 17-KGS is not very good (P > 0.05). There is a negative correlation between 17-OHCS and 17-KS control values, and the correlation after ACTH is very poor. 17-KGS correlate well with 17-KS (P < 0.01).

The Sicca Syndrome (Sjögren's Syndrome)

The symptoms associated with the abnormal physiology in patients with hypofunction of the lachrymal, nasal, and salivary glands have been termed variously as the sicca syndrome or complex, Sjogren's syndrome, keratoconjunctivitis sicca, or filamentary keratitis. In 1933, Henrik Sjogren, an ophthalmologist, described 19 such patients, some with an associated polyarthritis and parotid swelling, as well as the microscopic changes in the conjunctivae, cornea, lachrymal, and salivary glands. 1 The main manifestations of the disorder were the dryness of the eyes and mouth with a chronic polyarthritis plus certain general symptoms, not all present in all cases, such as acrodermatitis, scleroderma, achylia, pernicious anemia, Raynaud's phenomenon, purpura, and alopecia. 2 Other recent reports have dealt with the historic aspects and clinical characteristics of the disorder 3,4 ; the microscopic features of biopsy and autopsy material, 5-7 and therapeutic regimens. 8-11 The protean nature of this condition reflects a multisystemic involvement including features seen in the more

ACTIVE IMMOBILIZATION FOR RECURRENT OR CHRONIC POLYARTHRITIS

Medical Journal of AustraliaVolume 1, Issue 8 p. 287-290 Original Article ACTIVE IMMOBILIZATION FOR RECURRENT OR CHRONIC POLYARTHRITIS† Michael Kelly M.D., Michael Kelly M.D. MelbourneSearch for more papers by this author Michael Kelly M.D., Michael Kelly M.D. MelbourneSearch for more papers by this author First published: 01 February 1960 https://doi.org/10.5694/j.1326-5377.1960.tb105365.xCitations: 1 †A lecture, illustrated by a 30 mm. film, delivered on November 7, 1958, at Williamstown Hospital. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume1, Issue8February 1960Pages 287-290 RelatedInformation

Latex fixation test and lupus erythematosus cell test; studies on their diagnostic and etiological significance in primary chronic polyarthritis

Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study

Grundriss der inneren Medizin.

This is the twenty-second edition of a manual written primarily for the use of medical students. The large number of editions since its first publication by Domarus, in 1923, seems to indicate its popularity in Germany. To the American reader this book has a number of confirming aspects, a few of which should be pointed out. The German Die (p. 574), under the general heading of diseases of the joints, has nothing to do with our concept of rheumatoid arthritis. Rheumatoide are, rather, afflictions of the joints secondary to scarlet fever and other infectious diseases. Also, joint involvements after serum injections are taken into this group. Strumpell-Pierre-Marie's disease is viewed as caused by infection. Consequently, it is torn out of the American concept of rheumatoid arthritis, which, by the way, is named chronic polyarthritis and not considered a collagen disease. The collagen diseases as an entity are given short-shrift

Observations of multiple infections in chronic polyarthritis and the conception of a complex etiology.

Acta Medica ScandinavicaVolume 154, Issue S312 p. 417-418 Observations of Multiple Infections in Chronic Polyarthritis and the Conception of a Complex Etiology Alf Westergren, Alf Westergren St. Göran's Sjukhus, Stockholm, SwedenSearch for more papers by this author Alf Westergren, Alf Westergren St. Göran's Sjukhus, Stockholm, SwedenSearch for more papers by this author First published: January/December 1956 https://doi.org/10.1111/j.0954-6820.1956.tb17023.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume154, IssueS312January/December 1956Pages 417-418 RelatedInformation

Gold-testing in gold treatment of chronic polyarthritis; results of continued experiments.

Gold-testing in gold treatment of chronic polyarthritis; results of continued experiments.

IV. Peripheral Ischaemia as the Basis of Joint Disease (serial angiography of the Periarticular blood vessels)

The radiographic visualisation of periarticular vessels offers an extension of the scope of arthrography. The diagnostic field is widened beyond the limits of the joint space to include the periarticular vascular and connective tissues. Peripheral vascular damage affects the texture of all tissues concerned with joint function—bones, muscles, nerves, and ligaments. The articular cartilage is particularly sensitive to any restriction of the peripheral circulation. The connection between circulatory damage and the development of joint changes will be illustrated by the example of the primary chronic polyarthritis of the hand, a very frequent and important joint lesion. Evidence will be presented on the effects of ischaemia due to lesions of the vessels in causing joint changes. Morbid anatomists and clinicians such as Brogsitter, Klinge, Lewis, Pemberton, Ratschow, and others have previously drawn attention to vascular changes in rheumatoid joint disease. We can now perform a direct visualisation of these v...

Serum antistreptolysin level; observation of 104 cases

Summary1. 180 determinations of antistreptolysin level in serum were performed in 104 patients with various diseases. This research attempted to assess the diagnostic value of the test.2. In most cases of rheumatic fever, the antistreptolysin level is increased; it is usually normal in chronic polyarthritis.3. In the other joints diseases (tuberculous, gonococcal arthritis, …), there is usually no increase in the antistreptolysin level.4. Antistreptolysin level is increased in acute nephritis following streptococcal infection ; it is normal in chronic nephritis.5. It is high after angina and erythema nodosum of streptococcal origin.6. The rise of antistreptolysin above normal may be considered as characteristic of an hemolytic streptococcal infection.

CHRONIC POLYARTHRITIS AND MONARTICULAR TRAUMA

Medical Journal of AustraliaVolume 2, Issue 6 p. 197-198 Original Article CHRONIC POLYARTHRITIS AND MONARTICULAR TRAUMA Michael Kelly, Michael Kelly MelbourneSearch for more papers by this author Michael Kelly, Michael Kelly MelbourneSearch for more papers by this author First published: 01 August 1951 https://doi.org/10.5694/j.1326-5377.1951.tb68211.xRead the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume2, Issue6August 1951Pages 197-198 RelatedInformation

Therapeutic results in primary chronic polyarthritis with sanocrysin according to K. Secher

Die Sanocrysintherapie der Polyarthritis chronica primaria, so wie sie von K. Secher begrundet und durchgefuhrt wurde, wird besprochen. Dabei wird die Frage einer evtl. gemeinsamen Atiologie mit der Tuberkulose angedeutet. Die Bedeutung der neben der Sanocrysinbehandlung herlaufenden physikalischen Anwendungen wird kurz umrissen. Die gunstigere Prognose der mit Sanocrysin behandelten Kranken zeigt sich in der wesentlich geringeren Progression des Leidens, indem die Erkrankung im I. Stadium bei Sanocrysinbehandlung nach 5 Jahren in 12%, nach 10 Jahren in 32% der Falle in das II. Stadium fortgeschritten ist. Bei dem Kontrollmaterial (rein physikalische Behandlung) handelt es sich um 65% und 92% der Falle. Im II. Stadium sind es unter Sanocrysinbehandlung 22% und 55%, im Kontrollmaterial 60% und 86% der Falle, die in das III. Stadium ubergegangen waren.

A Method for the Quantitative Roentgenological Determination of the Amount of Calcium Salts in Bone Tissue: Its Use in the Study of Calcium Reduction in the Phalanges of the Fingers in Chronic Polyarthritis

A Method for the Quantitative Roentgenological Determination of the Amount of Calcium Salts in Bone Tissue: Its Use in the Study of Calcium Reduction in the Phalanges of the Fingers in Chronic Polyarthritis

A Method for the Quantitative Roentgenological Determination of the Amount of Calcium Salts in Bone Tissue:Its Use in the Study of Calcium Reduction in the Phalanges of the Fingers in Chronic Polyarthritis

A Method for the Quantitative Roentgenological Determination of the Amount of Calcium Salts in Bone Tissue:Its Use in the Study of Calcium Reduction in the Phalanges of the Fingers in Chronic Polyarthritis

Haemolytic stryptococcii antigene agglutination tests in patients suffering from chronic polyarthritis

Acta Medica ScandinavicaVolume 130, Issue S206 p. 454-455 Haemolytic stryptococcii antigene agglutination tests in patients suffering from chronic polyarthritis K. Kalbak, K. Kalbak CopenhagenSearch for more papers by this author K. Kalbak, K. Kalbak CopenhagenSearch for more papers by this author First published: January/December 1948 https://doi.org/10.1111/j.0954-6820.1948.tb12081.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume130, IssueS206January/December 1948Pages 454-455 RelatedInformation

Chronic Polyarthritis in Denmark

Acta Medica ScandinavicaVolume 130, Issue S206 p. 437-442 Chronic Polyarthritis in Denmark A. Norgaard, Search for more papers by this author A. Norgaard, Search for more papers by this author First published: January/December 1948 https://doi.org/10.1111/j.0954-6820.1948.tb12078.xCitations: 2AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinked InRedditWechat Citing Literature Volume130, IssueS206January/December 1948Pages 437-442 RelatedInformation

Felty's Syndrome: Splenomegalia, Leucopenia and Chronic Polyarthritis. — Familial Occurrence.

Acta Medica ScandinavicaVolume 120, Issue 6 p. 543-567 Felty's Syndrome: Splenomegalia, Leucopenia and Chronic Polyarthritis. — Familial Occurrence. JOHANNES ZIMMER, JOHANNES ZIMMER St. Joseph's Hospital, Porsgrunn, Norway. Physician-in-Chief August Schrumpf.Search for more papers by this author JOHANNES ZIMMER, JOHANNES ZIMMER St. Joseph's Hospital, Porsgrunn, Norway. Physician-in-Chief August Schrumpf.Search for more papers by this author First published: January/December 1945 https://doi.org/10.1111/j.0954-6820.1945.tb11943.xCitations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume120, Issue6January/December 1945Pages 543-567 RelatedInformation

AMYLOIDOSIS IN CHRONIC ATROPHIC ARTHRITIS

Case Reports1 May 1943AMYLOIDOSIS IN CHRONIC ATROPHIC ARTHRITISWALTER M. SOLOMON, M.D.WALTER M. SOLOMON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-5-846 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince amyloid infiltration was first brought to the attention of the medical profession by Rokitansky and the Viennese school only a few cases of amyloidosis associated with chronic arthritis have been reported. This relative sparsity of reports prompts the discussion of the following case.Amyloidosis most frequently complicates tuberculosis and other diseases in which chronic suppuration occurs, such as osteomyelitis, pulmonary abscess, pyelonephritis and others. Certain chronic diseases which lack obvious suppurative processes but have occasionally shown amyloid deposits are Hodgkin's disease, cirrhosis of the liver, leukemia and myeloma. Amyloidosis has been found also in nonsuppurative infectious diseases such as...Bibliography1. SCHNEIDERBAUER A: Amyloid and lipoid nephrosis in chronic polyarthritis, Ztschr. f. klin. Med., 1938, cxxxiii, 643-647. Google Scholar2. HARDGROVE MA: Retention of Congo red in amyloid disease, Arch. Path., 1933, xv, 238-243. Google Scholar3. REIMANNEKLUND HACM: Long continued vaccine therapy as a cause of amyloidosis, Am. Jr. Med. Sci., 1935, cxc, 88. CrossrefGoogle Scholar4. MOSCHCOWITZ E: Clinical aspects of amyloidosis, ANN. INT. MED., 1936, x, 73-78. Google Scholar5. LENGH F: Case of amyloid deposits in joints, Zentralbl. f. allg. Path. u. path. Anat., 1937, lxix, 1-5. Google Scholar6. IMRIEAITKENHEAD AHAC: Amyloidosis complicating Still's disease, Lancet, 1939, ii, 421. CrossrefGoogle Scholar7. PORTIS RB: Pathology of chronic arthritis of children (Still's disease), Am. Jr. Dis. Child., 1938, lv, 1000-1017. Google Scholar8. KOLETSKYSTECHER SRM: Primary systemic amyloidosis, Arch. Path., 1939, xxvii, 267-288. Google Scholar9. FELLER F: Case of amyloid, Zentralbl. f. allg. Path. u. path. Anat., 1935, lxiii, 123. Google Scholar10. MICHELSONLYNCH HEFW: Systematized amyloidosis of skin and muscles, Arch. Dermat. and Syph., 1935, xxxii, 363-369. CrossrefGoogle Scholar11. PERLAGROSS DH: Atypical amyloid disease, Am. Jr. Path., 1935, xi, 93-112. Google Scholar12. DICKLEITER GFL: Amyloidosis and hyperglobulinemia, Trans. Assoc. Am. Phys., 1937, lii, 246-249. Google Scholar13. ARNDTDOERKEN HJE: Amyloidosis in horses used in preparations of serums, Arch. f. wissensch. u. prakt. Tierh., 1931, lxiii, 1-11. Google Scholar14. SIPOS J: Abstr. in Hajrest. Veter. Med., 1930, l, 795. Google Scholar15. LETTERER E: Studies concerning the formation of amyloid, Beitr. z. path. Anat. u. z. allg. Path., 1926, lxxv, 486-588. Google Scholar16. GRAYZELJACOBIWARSHALLBOGINBOLKER HGMHBMH: Amyloidosis, Arch. Path., 1933, xvii, 50-75. Google Scholar17. Cabot Case Record—Case 19142, Chronic arthritis with recent edema of the feet, New England Jr. Med., 1933, ccviii, 757-759. Google Scholar18. EKLUNDREIMANN CMHA: The etiology of amyloid disease, Arch. Path., 1936, xxi, 1-9. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication January 30, 1941.From the Department of Medicine of the St. Alex Hospital and the School of Medicine of Western Reserve University. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAmyloidoseThe kidney in rheumatoid arthritis: Studies by renal biopsyHepatic Manifestations in Secondary Amyloidosis 1 May 1943Volume 18, Issue 5Page: 846-850KeywordsAmyloidosisArthritisHodgkin lymphomaHospital medicineInfectious diseasesLiverMyelomaOsteomyelitisPulmonary diseasesPyelonephritis ePublished: 1 December 2008 Issue Published: 1 May 1943 PDF downloadLoading ...

NECROSCLERITIS NODOSA ASSOCIATED WITH CHRONIC RHEUMATOID POLYARTHRITIS

In 1934 van der Hoeve 1 reported 4 cases of a new disease which he had named scleromalacia perforans. Two of the cases were his own and the other 2 belonged to Rochat, who had independently named the condition scleritis necroticans. Scleromalacia perforans was described as a degenerative disease, accompanied by little or no inflammation and characterized by the appearance of multiple holes in the sclera. Some of the holes were covered by conjunctiva. Others exposed bare uvea to the outside. Adjacent holes often coalesced. The patients in all 4 cases were elderly. Three had advanced chronic rheumatic polyarthritis. One never had had any symptoms of arthritis. Van der Hoeve also mentioned that he had heard of the existence of 2 more cases of this disease, although he had not seen either of the patients. Both were reported as being elderly, and 1 suffered from chronic arthritis. Apparently all 4

LYMPHOGRANULOMA INGUINALE

It is generally assumed that the lesions of lymphogranuloma inguinale are limited to those of primary infection and local bubo.1There are many observations on record,2however, of fever, rigors, malaise, weakness, loss of weight and such rheumatoid manifestations as erythema nodosum, episcleritis, periarticular pains and polyarthritis, and some authors have therefore suggested that the disease may at times spread beyond the local lymphatic barrier. Frauchiger3recently described two cases of anorectal syndrome with a positive Frei reaction, which exhibited chronic polyarthritis affecting the elbows, knees and wrists. The arthritic manifestations of one patient improved on resection of the rectum. In the other a para-articular abscess was discovered, which proved to be sterile by ordinary methods of bacteriologic examination. Whether these phenomena are produced by the virus or are merely expressions of sensitization to a foreign protein is yet uncertain. The fact that the virus of

Diagnostic and therapeutic injections of the sympathetic nerves

The most satisfactory diagnostic procedure for conditions affected by the sympathetic nervous system is the direct injection of procaine at the sympathetic nerves. By means of these diagnostic injections it is possible to determine accurately whether or not therapeutic measures should be directed toward the sympathetic nervous system. The two factors most frequently involved are pain and diminished blood supply. Diagnostic injection gives definite information as to relief of pain and what quantitative increase in vascularity may be obtained by therapeutic measures. Alcohol injection of the sympathetic nerves is an established therapeutic measure. We have used it successfully in arteriosclerotic conditions, Buerger's disease, Raynaud's disease, chronic polyarthritis, trifacial neuralgia, atypical facial pains, angina pectoris, trophic ulcers, neurotrophic skin lesions, diabetic neuritis, and other conditions. Tables are presented including 64 diagnostic injections, 48 of which were followed by alcohol injection with uniformly good results. Alcohol injection may be used as a substitute for surgical removal of sympathetic ganglia where the latter is not indicated. Alcohol injection does not have the permanency of the operation and is therefore not indicated where permanent maximum blood supply is essential except where operation is definitely contraindicated. Alcohol injection can be used more successfully than the LeRiche operation in all of the conditions for which this operation has been advocated. Surgery or alcohol injection on the sympathetic nervous system should be preceded by diagnostic procaine injection. This diagnostic injection has taken guess work entirely out of the realm of sympathetic therapeutic measures.