Journal of Integrative NeuroscienceVol. 09, No. 01, pp. 1-10 (2010) Short CommunicationNo AccessTHE PREDICTIVE VALUE OF PAIN EVENT-RELATED POTENTIALS FOR THE CLINICAL EXPERIENCE OF PAINHELEN VOSSEN, JIM VAN OS, HERMIE HERMENS, and RICHEL LOUSBERGHELEN VOSSENDepartment of Psychiatry and Psychology, Maastricht University, P.O. Box 5800, 6202 Az Maastricht, The Netherlands Search for more papers by this author , JIM VAN OSDepartment of Psychiatry and Psychology, Maastricht University, P.O. Box 5800, 6202 Az Maastricht, The Netherlands Search for more papers by this author , HERMIE HERMENSRoessigh Research and Development, Roessinghsbleekweg 33b, 7522 AH Enschede, The Netherlands Search for more papers by this author , and RICHEL LOUSBERGDepartment of Psychiatry and Psychology, Maastricht University, P.O. Box 5800, 6202 Az Maastricht, The Netherlands Search for more papers by this author https://doi.org/10.1142/S0219635210002354Cited by:1 Next AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail AbstractEvent-related potentials (ERPs) have been found to be related to subjective experience of experimental pain. But how are they related to the subjective experience of clinical pain? The current study investigated the predictive value of the pain ERP for the subjective experience of clinical pain. Event-related potentials in response to experimental pain were measured in 75 chronic low back pain sufferers. In addition, a two-week registration to note the amount of pain they experienced in daily life was done. The results demonstrate that the N2-component at Cz and C4 of the pain ERP (contralateral to the side of the stimulation) were significant predictors of clinical pain, and even stronger predictors than the accompanying subjective ratings of experimental pain. Thus, it seems promising to use event-related potentials as a more objective measure to make predictions about a person's likely pain experience in daily life.Keywords:Event-related potentialschronic painpredictive value References P. M. Aslaksen and M. A. Flaten, Psychosom. Med. 70, 811 (2008), DOI: 10.1097/PSY.0b013e31818105ed. Crossref, Medline, ISI, Google ScholarB. Bromm and W. Meier, Meth. Find in Exp. Clin. Pharmacol. 6, 405 (1984). Medline, ISI, Google ScholarB. Bromm, Pain Measurement in Man: Neurophysiological Correlates of Pain, ed. B. Bromm (Elsevier, Amsterdam, 1984) pp. 257–290. Google ScholarD. E. Beckeret al., Pain 84, 37 (2000), DOI: 10.1016/S0304-3959(99)00182-7. Crossref, Medline, ISI, Google ScholarJ. Benvenutoet al., Exp. Neurol. 176, 269 (2002), DOI: 10.1006/exnr.2002.7930. Crossref, Medline, ISI, Google ScholarJ. Daltrozzoet al., Clin. Neurophysiol. 118, 606 (2007), DOI: 10.1016/j.clinph.2006.11.019. Crossref, Medline, ISI, Google ScholarA. Farmanet al., Neuropsychiatr. Dis. Treat. 4, 959 (2008). Medline, Google Scholar Hoekstra HA, Ormel J, de Fruyt F, NEO-PI-R – NEO FFI, Big five persoonlijkheidsvragenlijsten, Handleiding, Lisse, Swets & Zeitlinger, 1996 . Google ScholarE. C. Huskisson, Lancet 9, 1127 (1974). Medline, ISI, Google ScholarH. H. Jasper, J. Electroenceph. Clin. Neurophysiol. 20, 371 (1958). Google ScholarM. Kandaet al., Clin. Neurophysiol. 113, 1013 (2002), DOI: 10.1016/S1388-2457(02)00125-6. Crossref, Medline, ISI, Google ScholarA. H. Kempet al., J. Integr. Neurosci. 5, 89 (2006), DOI: 10.1142/S0219635206001069. Link, Google ScholarF. M. Kovacset al., BMC. Musculoskelet. Disord. 9, 9 (2008). Medline, ISI, Google ScholarE. E. Labbé, L. Murphy and C. O'Brien, Headache 37, 1 (1997). Crossref, Medline, ISI, Google ScholarR. Lousberg, A. J. Schmidt and N. H. Groenman, Pain 51, 75 (1992), DOI: 10.1016/0304-3959(92)90011-Y. Crossref, Medline, ISI, Google ScholarI. Myin-Germeyset al., Psycholog. Med. 12, 1 (2009). Medline, ISI, Google ScholarT. V. Perneger, BMJ 316, 1236 (1998). Crossref, Medline, ISI, Google ScholarL. Schwartz and G. H. Kraft, Am. J. Phys. Med. Rehabil. 78, 525 (1999), DOI: 10.1097/00002060-199911000-00006. Crossref, Medline, ISI, Google ScholarH. Stowell, Brain. Res. Bull. 2, 23 (1977), DOI: 10.1016/0361-9230(77)90021-1. Crossref, Medline, ISI, Google ScholarP. D. Wall, J. Psychophysiol. 188, 403 (1964). Google ScholarR. Zaslanskyet al., Pain 66, 39 (1996), DOI: 10.1016/0304-3959(96)03020-5. Crossref, Medline, ISI, Google Scholar FiguresReferencesRelatedDetailsCited By 1Parameter pattern discovery in nonlinear dynamic model for EEGs analysisSun-Hee Kim, Christos Faloutsos, Hyung-Jeong Yang, and Seong-Whan Lee18 November 2016 | Journal of Integrative Neuroscience, Vol. 15, No. 03 Recommended Vol. 09, No. 01 Metrics History Received 28 October 2009 Accepted 12 January 2010 KeywordsEvent-related potentialschronic painpredictive valuePDF download
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