This paper provides a comprehensive study and detailed description of the state-of-the-art of the issue of postoperative adhesions, methods to prevent this complication, and factors that contribute to reducing the risk of adhesions. Adhesions are one of the most common complications of surgical interventions. Abdominal and pelvic surgery can provoke chronic pain, infertility, intestinal obstruction, and other complications. Despite the availability and active use of high-tech medical equipment, adhesions can complicate every surgical procedure. Extensive research has now led to a better understanding of the process of adhesion formation; cellular hypoxia is hypothesized to play a crucial role. A deeper understanding of the factors that provoke adhesions will improve technologies and the development of novel methods of prevention and treatment of adhesions This will result in a clinically relevant improvement of current approaches employed to prevent postoperative adhesions The gold standard for the prevention of adhesions is a qualified surgical technique and care to minimize tissue trauma, particularly to the peritoneum. In the future, drugs for the prevention of adhesions and measures to reduce their severity will become increasingly important KEYWORDS: adhesions, anti-adhesion barriers, laparoscopy, gynecology, prevention, postoperative adhesions. FOR CITATION: Gudz' O.V., Sulima A.N., Glazkov I.S., Rumyantseva Z.S., Miklin O.P., Ermachkova P.A. Anti-adhesion barriers in operative gynecology. Russian Journal of Woman and Child Health. 2024;7(2):144–149 (in Russ.). DOI: 10.32364/2618-8430-2024-7-2-9.