Chronic Disease Questionnaire Research Articles

Clinical and individual factors of quality of life of chronic liver disease patients at University of Gondar comprehensive specialized hospital, Northwest Ethiopia 2022.

Chronic liver disease (CLD) may be a major cause of morbidity and mortality worldwide, as well as a reduction in health-related quality of life. In Ethiopia, however, little is known about the effect of CLD on quality of life. The purpose of this study was to evaluate CLD patients' health-related quality of life and associated factors. A cross-sectional study was carried out on 227 CLD patients who were being followed up on at the University of Gondar specialized hospital between January 2022 and February 2022. To assess health-related quality of life, the chronic disease Questionnaire was used. Epi-Data version 4.6 was used to enter data, and SPSS version 25 was used for all statistical analysis. To identify factors associated with the outcome variable, a linear regression model was used. Patients with CLD had significantly lower mean scores in all domains of health-related quality of life. Hepatitis B virus treatments and a college education or higher have a positive effect on all domains of health-related quality of life. Upper gastrointestinal bleeding, spontaneous bacterial peritonitis (SBP), hepatic encephalopathy (HE), and ascites were a clinical related factors significantly associated with poor health-related quality of life in simple linear regression. In this study setting, all dimensions of health-related quality of life of patients with CLD were compromised. Antiviral treatment for HBV infection, beta-blocker treatment, and the presence of complications such as ascites were all found to be significantly related to health-related quality of life. This necessitates going above and beyond standard treatments to improve patients' quality of life with CLD.

Double Stigma in Portuguese Lesbian, Gay, and Bisexual Older Adults: A Study of Health Status

The double stigma—sexual stigma and ageism—can affect the health status of lesbian, gay, and bisexual (LGB) older adults, but little is known about this topic in Portugal and internationally. The aim of this study was to assess the health status and the prevalence of chronic diseases of Portuguese LGB older adults, as well as to assess the relationship between double stigma and health status. A sample of 280 Portuguese LGB older adults completed a chronic disease questionnaire, the Homosexuality-Related Stigma Scale, the Ambivalent Ageism Scale, and the SF-12 Short Form Health Survey. A structural equation model was performed using the double stigma variables as independent variables and health status as outcome. The mental health status of Portuguese LGB older adults was lower when compared to people from studies from more than 10 countries. Higher sexual self-stigma, sexual enacted stigma related to health care, and benevolent ageism significantly explained the worse general health status. The double stigma significantly affects the health status of these older adults in a profile of internalization of sexual stigma and benevolent age discrimination, and not necessarily by a hostile/aggressive profile. More research is needed on the double stigma.

Knowledge, attitude, behaviour, and influencing factors of home-based medication safety among community-dwelling older adults with chronic diseases: a cross-sectional study

BackgroundOlder adults with chronic diseases require long-term medication. However, due to lack of drug knowledge and hypomnesia, older adults with chronic diseases are prone to adverse drug events and increased medical costs. This study aimed to explore the status and influencing factors of home-based medication safety among community-dwelling older adults with chronic diseases in China to provide a basis for follow-up to conduct targeted health education.MethodsOverall, 427 community-dwelling older adults with chronic diseases participated in this study. The Knowledge, Attitude, and Behaviour of Medication Safety among Older Adults with Chronic Diseases Questionnaire was used to assess their home-based medication safety. Multivariate linear regression was used to identify the factors influencing knowledge, attitude, and behaviour regarding medication safety.ResultsThe average score of home-based medication safety among older adults with chronic diseases was 68.26 ± 8.96, indicating that they had a moderate grasp of medication safety. The scoring rate of each subscale was ranked from high to low as follows: behaviour (84.51%), knowledge (63.33%), and attitude (47.39%). Stepwise linear regression analysis showed that medication safety knowledge, attitudes, and behaviours were significantly associated with higher monthly income, adverse drug events, and taking medicine several times a day (p < 0.05). Additional influencing factors included having fewer chronic diseases, being female, higher educational attainment, taking medicines multiple kinds a day, better self-care ability, and non-hospitalisation for chronic illnesses (p < 0.05).ConclusionMedical staff and community workers should pay attention to the drug safety of older adults with different characteristics and mobilise their enthusiasm for participation to improve their medication self-management ability.Trial registrationChinese Clinical Trial Register: ChiCTR2200060987; reg. date: 15/06/2022.

Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD).

Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD).

Cardiovascular Health in a Single Community in Rural Haiti: A Cross-sectional Study

IntroductionThere is a growing burden of cardiovascular disease in low- and middle-income countries and assessment of cardiovascular health (CVH) may identify populations at risk for poor CVH.MethodsBetween July 2014 and August 2014, we performed a household survey from a convenience sample among adult community members in rural northern Haiti. We used a modified World Health Organization STEPwise approach to chronic disease questionnaire to capture self-reported data on tobacco, diet, physical activity, and diabetes, and measured blood pressure and body mass index. We used an adapted American Heart Association definition and thresholds for determining ideal, intermediate, and poor cardiovascular health. We used linear and logistic regression to examine associations between socio-demographic characteristics with CVH score and ideal CVH.ResultsAmong 540 participants (mean [SD] age = 40.3 [17.1] years, 67% women), there was a high prevalence of poor CVH (n=476, 88.1%) compared with intermediate (n=56, 10.4%) and ideal (n=41, 7.6%) CVH. Ideal metrics for blood pressure (47%) and diet (26%) were least often met, while body weight (84%), physical activity (83%), and smoking (90%) were most often met. Men were associated with better CVH score (0.31, [0.04–0.59]; P=0.03), and being a farmer was associated with ideal CVH (P=0.006).ConclusionIn this community-based sample of a farming community in rural Haiti, very few adults had ideal CVH. Higher CVH score was associated with male sex, and farming as a primary occupation. Women and non-farmers may represent at-risk subgroups within this population. Blood pressure and diet may represent possible areas for improvement.

Self-Efficacy and Social Support are Associated with Disability for Ambulatory Prosthesis Users After Lower-Limb Amputation.

Interventions targeting psychosocial factors may improve rehabilitation outcomes for prosthesis users after lower-limb amputation (LLA), but there is a need to identify targeted factors for minimizing disability. To identify psychosocial factors related to disability for prosthesis users after LLA in middle age or later. Cross-sectional study. General community. Participants with LLA (N = 122) were included in this cross-sectional study if their most recent LLA was at least 1 year prior, they were ambulating independently with a prosthesis, and they were between 45 and 88 years old. Not applicable. Disability, the primary outcome, was measured using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS). Candidate psychosocial variables included self-efficacy, social support, and motivation, measured using the Self-Efficacy of Managing Chronic Disease questionnaire (SEMCD), Multidimensional Scale of Perceived Social Support questionnaire (MSPSS), and modified contemplation ladder (mCL), respectively. The hypothesis was that greater self-efficacy, social support, and motivation would be associated with lower disability when controlling for covariates. The covariate model, including etiology, age, sex, U.S. military veteran status, LLA characteristics, time since LLA, medical complexity, and perceived functional capacity, explained 66.1% of disability variability (WHODAS 2.0). Backward elimination of candidate psychosocial variables stopped after removal of motivation (P = .10), with self-efficacy (P < .001) and social support (P = .002) variables remaining in the final model. The final model fit was statistically improved (P < .001) and explained an additional 6.1% of disability variability when compared to the covariate model. Greater self-efficacy and social support are related to lower disability after LLA. Findings suggest there may be a role for interventions targeting increased physical function, self-efficacy, and social support for ambulatory prosthesis users after LLA in middle age or later, especially when complicated by multiple chronic conditions.

Epidemic of chronic diseases and the related healthy lifestyle interventions in rural areas of Shandong Province, China

BackgroundThere were amounts of previous studies on chronic diseases, but few studies on the prevalence of chronic disease and the healthy lifestyle intervention in recent years, China. This study aimed to investigate the prevalence of chronic disease and the implementation of healthy lifestyle intervention in rural areas of China, so as to put forward health promotion measures to control the chronic diseases effectively.MethodA large cross-sectional study (N = 2168) on community diagnosis and chronic disease was carried out in Shandong province, China. The chronic disease questionnaire and the healthy lifestyle intervention questionnaires were recruited to survey the chronic diseases and the implementation of healthy lifestyle intervention. Physical examination and biochemical indicators examination were carried out by the medical staffs and clinical laboratory.ResultsThe current diagnosed prevalence of hypertension, diabetes, hyperlipidemia for total sample, female, male were 24.97, 24.6, 25.5, 7.60, 8.9, 6.0 and 40.27%, 45.9, 33.3% respectively in rural China. The one-year prevalence of myocardial infarction (MI) and stroke of the total sample, female, male were 1.06, 1.0, 1.1 and 2.09%, 2.2, 2.0% respectively.Healthy lifestyles interventions were not effective in rural China. The current active smoking rate and passive smoking rate were 25.68 and 42.65%. 27.86% of the population drunk alcohol within a month and 47.01% of them participated in the actions to control salt daily intake. Only 1.07 and 7.89% of the population participated in medium to high intensity physical exercises.ConclusionsThe prevalence of common chronic diseases were still high and the implementation of healthy lifestyle intervention were not optimal in rural area, China. Challenges to prevent chronic diseases were still severe, so medical institutes, government and individuals would put forward effective strategies to reduce the prevalence and public health promotion project should be effectively strengthened.

Childhood vitiligo impacts emotional health of parents: a prospective, cross-sectional study of quality of life for primary caregivers

Background/objectivesIndividuals with vitiligo have an increased risk of depression, anxiety, social isolation and detrimental effects on body image/self-esteem. However, assessments of quality of life (QoL) impact have not focused on caregivers of children with vitiligo. To address this, we determined the QoL impact in parents of children with vitiligo to assess the relationship between QoL parameters and disease duration, location, and severity.MethodsWe performed a cross-sectional study involving 123 parents of children diagnosed with vitiligo for at least 3 months, and who presented to the pediatric dermatology clinic of a major United States children’s hospital. Parents completed a demographics survey, Quality of Life in a Child’s Chronic Disease Questionnaire (QLCCDQ) and Family Dermatology Life Quality Index (FDLQI) to assess QoL measures. The lower the QLCCDQ score and higher the FLDQI score, the more quality of life is impaired.ResultsSubject age ranged from 20 to 57, and 13.9% received mental health intervention. QLCCDQ emotional domain scores were most impaired, and severity and location of disease impacted these scores. FDLQI scores decreased as children age, indicating overall parent wellbeing increased as children age.ConclusionsChildhood vitiligo has great emotional impact on the quality of life of caregivers. Recognizing this will enable dermatologist who primarily care for these patients to incorporate care giver specific interventions during clinical visits. Emotional domain scores for parents of children with vitiligo were the most impaired as much or more than of those seen in parents of children with chronic stable medical disease such as type 1 diabetes and asthma.

Effect of motivational interviewing on health literacy and quality of life of patients on maintenance hemodialysis

Objective To investigate the effect of motivational interviewing on literacy and quality of life of patients on maintenance hemodialysis. Methods Using convenience sampling method, 100 patients on maintenance hemodialysis were selected from March 2016 to March 2018 in a blood purification center of a Class Ⅲ Grade A hospital. According to dialysis time, the patients were divided into the intervention group (n=50) and control group (n=50) . Motivational interviews were conducted in the intervention group. Traditional education methods were used in the control group. The two groups' scores in literacy and quality of life from Health Literacy of Patients with Chronic Diseases Questionnaire and Kidney Disease Questionnaire (KDQ) before and after intervention were compared. Results After 6 months of intervention, the total score of literacy in the intervention group increased from (87.34±2.85) to (97.34±3.02) . The scores of three dimensions of information acquisition ability , communication and interaction ability and willingness to improve health were higher than those before intervention, and the total score of literacy and above three dimensions in the intervention group were higher than those in the control group with statistical differences (P<0.05) . The total score of quality of life in the intervention group increased from (100.64±17.62) to (115.60±16.15) , among which the scores of somatic symptoms , fatigue and relationship with others in the intervention group were higher than those before intervention, and the total score of quality of life and the above three dimensions in the intervention group were higher than those in the control group, the differences were statistically significant (P<0.05) . Conclusions Motivational interviews can improve the literacy level of maintenance hemodialysis patients, enhance their awareness of improving health, change their bad behaviors, and improve their quality of life. Key words: Dialysis; Quality of life; Health literacy; Motivational interviewing

Severity of disease and quality of life in parents of children with alopecia areata, totalis, and universalis: A prospective, cross-sectional study

Caregiver-oriented quality of life (QoL) research in alopecia areata is limited. No study has used a parent-tailored survey to examine the relationship between QoL and severity of alopecia as measured by Severity of Alopecia Tool (SALT) scores. This is a prospective study that describes QoL in parents of pediatric patients with all subtypes of alopecia areata and investigates the relationship between QoL and severity of disease, duration of disease, and age of patients. Pediatric patients and their parents were invited to participate during clinic visits. Participating parents completed the Quality of Life in a Child's Chronic Disease Questionnaire (QLCCDQ) and the Family Dermatology Life Quality Index (FDLQI). A subset of children completed the Children's Dermatologic Life Quality Index (CDLQI). SALT scores at time of survey completion were recorded. In total, 153 patients were included. Significant mild-to-moderate negative correlations were found between SALT scores and FDLQI scores, QLCCDQ scores, and QLCCDQ emotional domain scores. Age of child correlated negatively with QLCCDQ scores but not FDLQI scores. No significant correlation was found between duration of disease and FDLQI scores, QLCCDQ scores, or QLCCDQ emotional domain scores. This study is limited by its small sample size and cross-sectional design. Impaired parent QoL might be associated with increasing severity of disease and age ofaffected child but not duration of disease. Providers should tailor counseling accordingly and help parents set realistic expectations for long-term experience with the disease.

Relationships Among Perceived Functional Capacity, Self-Efficacy, and Disability After Dysvascular Amputation

BackgroundProsthesis rehabilitation after dysvascular transtibial amputation (TTA) is focused on optimizing functional capacity with limited emphasis on promoting health self-efficacy. Self-efficacy interventions decrease disability for people living with chronic disease, but the influence of self-efficacy on disability is unknown for people with dysvascular TTA. ObjectivesTo identify if self-efficacy mediates the relationship between self-reported functional capacity and disability after dysvascular TTA. DesignCross-sectional, secondary data analysis. SettingOutpatient rehabilitation facilities. ParticipantsThirty-eight men (63.6 ± 9.1 years old) with dysvascular TTA. MethodsParticipants had been living with an amputation for less than 6 months and using walking as their primary form of locomotion using a prosthesis. The independent variable, functional capacity, was measured using the Prosthesis Evaluation Questionnaire–Mobility Scale (PEQ-MS). The proposed mediator, self-efficacy, was measured with the Self-Efficacy of Managing Chronic Disease questionnaire (SEMCD). Main Outcome MeasureDisability was measured using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) questionnaire. ResultsThe relationship between self-reported functional capacity and disability is partially mediated by self-efficacy. Relationships between WHODAS 2.0 and PEQ-MS (r = –0.61), WHODAS 2.0 and SEMCD (r = –0.51), and PEQ-MS and SEMCD (r = 0.44) were significant (P < .01). Controlling for SEMCD (P = .04), the relationship between PEQ-MS and WHODAS 2.0 remained significant (P < .01). Statistically significant mediation was determined by a bootstrap method for the product of coefficients (95% confidence interval: –2.23, –7.39). ConclusionsThis study provides initial evidence that the relationship between self-reported functional capacity and disability is partially mediated by self-efficacy after dysvascular TTA. The longitudinal effect of self-efficacy should be further examined to identify causal pathways of disability after dysvascular amputation. Furthermore, additional factors contributing to the relationship between self-reported functional capacity and disability need to be identified. Level of EvidenceIII

Correlation between cognition of depression and anxiety and recognition of physical and mental illness in hospitalized elderly patients with chronic diseases

Objective To investigate the cognition of depression and anxiety and recognition of physical and mental illness, and analyze their correlation in hospitalized elderly patients with chronic diseases. Methods A cross-sectional study was performed. A total of 206 hospitalized elderly patients with chronic diseases from a hospital were investigated using mini mental state examination (MMSE), Hamilton depression rating scale (HAMD), self rating anxiety scale (SAS) and elderly patients with chronic diseases questionnaire. Results The total scores in cognition of depression and anxiety were (5.95±3.05) and (4.92±3.20). The correct recognition rate of chronic disease was (97±8)%, and the correct recognition rate of mental illness was (47±29)%. The recognition of mental illness was positively correlated with the total cognition score of depression and three dimensions of thinking, spirit and mood (P 0.05). There was no significant correlation between recognition of mental illness and physical dimension of anxiety (P>0.05). Conclusions The cognitive level and cognition of depression and anxiety are low in elderly patients with chronic diseases. They tend to recognize the mental illness as chronic physical disease. Therefore, nurses should make depression and anxiety evaluation as routine assessment for the elderly patients with chronic diseases. Early identification of mental illness can avoid the delay of psychological intervention and acquire the best time of treatment. Key words: Chronic diseases; Depression; Anxiety; Cognition; Correlation

Determinants of Quality of Life After Lung Transplantation

Background: The purpose of this study was to examine clinical and non- clinical determinants of quality of life (QoL) in lung transplant recipients (LTR). Methods: QoL was measured cross-sectional in 152 LTR (4.5±3.2 years after lung transplantation (LTx); 95 (63%) double LTx; 80 (53%) female; age 50±11.9 years; 28 (18%) bronchiolitis obliterans syndrome (BOS) stage ≥ 1) using the SF-36, the Quality of Life Profile for Chronic Diseases Questionnaire as well as the St. GeorgesRespiratory Questionnaire. Gender, age, body mass index (BMI), time after LTx, procedure type, underlying disease, marital- and professional status and exercise capacity (6-minute walk test, 6MWT) were tested for their predictive value by non-parametric significance tests and ANOVA and ANCOVA. Results: There was a significant correlation with higher physical QoL scores for age < 48 years (p<0.05), a BMI of 21.0 - 25.2 kg/m 2 (p<0.05), a 6MWT≥ 430m (p<0.001), for cystic fibrosis patients (p<0.05) without BOS (p<0.05) and who go to work (p=0.018). Females boasted a superior social health (p=0.04) and less respiratory symptoms (p=0.023). Double LTx was a significant predictor for both, mental and physical health (p<0.05). Subsequent analysis of covariance revealed only BMI (p=0.024), BOS stage (p<0.001), underlying disease (p=0.01) and exercise capacity according to 6MWT (p<0.001) as significant predictors for QoL independent of age. Conclusion: The study results suggest that returning to normal BMI and improving exercise capacity seem to be important therapeutic approaches to enhance QoL after LTx. Future investigations should focus on prophylaxis and therapy of BOS to further optimize QoL after LTx.

An occupation-based strategy training approach to managing age-related executive changes: a pilot randomized controlled trial

Objective: To determine the feasibility of recruitment and retention of healthy older adults and the effectiveness of an intervention designed to manage age-related executive changes. Design: A pilot randomized controlled trial. Setting: Research centre and participants’ homes. Participants: Nineteen healthy, community dwelling older adults with complaints of cognitive difficulties and everyday problems, but no evidence of mild cognitive impairment, dementia or depression on objective testing. Interventions: Seventeen hours of group and individual training. Participants in the experimental arm received education about self-management, successful aging and an occupation-based meta-cognitive strategy-training program. Participants in the control arm received education about brain health and participated in cognitively stimulating exercises. Main measures: Changes on untrained, everyday life goals were identified using the Canadian Occupational Performance Measure. Generalization of benefits was measured using the Stanford Chronic Disease Questionnaire, general self-efficacy and changes in executive function (Delis-Kaplan Executive Function System Tower Test, Word Fluency and Trail-Making Test). Results: 20% (19/96) of healthy older adults approached were eligible, consented and were enrolled in the study, 90% (17/19) were retained to three-month follow-up. Participants in the experimental arm reported significantly more improvement on untrained goals (11/22 compared with 9/46, χ2=4.92, p<0.05), maintenance of physical activity (p<0.05) and better preparation for doctors’ visits (p<0.05) relative to the control group. There were no significant between group differences on objective measures of executive function. Conclusions: These data support the feasibility of a larger trial where a sample of 72 (36 participants in each arm) would be required to confirm or refute these findings.

Health Related Quality of Life Following Single- Versus Double Lung Transplantation

Background: The purpose of this study was to investigate differences in health-related quality of life (HRQoL) in lung transplant recipients (LTR) undergoing single- vs. double lung transplantation. Methods: 95 double LTR and 57 single LTR of our lung transplantation (LTx) follow-up program (80 [53%] female, 4.5±3.2 years after LTx, age 50±11.9 years, 28 [18%] BOS stage≥1) were evaluated using the standardized global SF-36 questionnaire, the “Quality of Life Profile for Chronic Diseases Questionnaire” (PLC) as well as the specific “St. Georges' Respiratory Questionnaire” (SGRQ). Results: Both groups were statistically indistinguishable in terms of clinical data including BOS stage and follow-up time. Compared to single LTR, double LTR demonstrated a significantly higher quality of life regarding SF-36 “physical functioning” (p≤0.01), “general medical heath” (p=0.02), “mental health” (p=0.03) along with PLC “exercise capacity” (p=0.007), “ability to enjoy and relax” (p=0.003), “positive mood” (p=0.031) and “sociability” (p=0.007). Furthermore, HRQoL self-ratings of double LTR were significantly better in all SGRQ subscales (p≤0.01), indicating a superior disease specific HRQoL. Conclusion: Our data suggest that there are relevant HRQoL differences concerning type of transplant procedure. In our study double LTR had a significantly better generic and disease-specific quality of life following LTx. These findings need to be considered for future studies assessing outcome of LTx by HRQoL questionnaires.

130 Meeting established canadian benchmarks for access to heart failure (HF) care following emergency department visit and association with outcome

130 Meeting established canadian benchmarks for access to heart failure (HF) care following emergency department visit and association with outcome

131 Endothelial progenitor cells and functional capacity in heart failure patients

BACKGROUND: Prompt access to care that optimizes outcomes is crucial in the management of heart failure (HF). The Canadian Cardiology Society (CCS) recommends that patients should be seen within two weeks following an emergency department (ED) visit for HF. However, it is unknown whether lack of adherence to this benchmark translates into worse clinical outcomes. OBJECTIVE: The objective was to examine whether delay in consultation following an ED visit for HF was related to adverse outcomes/events (death, hospitalization or repeat ED visit). METHODS: Patients with a confirmed diagnosis of HF were recruited by nurses at 8 hospital EDs in Quebec, Canada. They were interviewed by telephone within 6 weeks of ED discharge and subsequently at 3 months and 6 months. They responded to questions related to use of health services, sociodemographic information, the Minnesota Living with Heart Failure Questionnaire, and the Stanford Self-Efficacy in Chronic Disease Questionnaire. Pertinent clinical variables were extracted from medical charts by trained nurses. We used Cox regression to analyze whether delayed medical follow-up following ED visit was associated with increased risk of adverse events independently of other clinical covariates. RESULTS: We recruited a total of 551 patients. The mean age was 75.5 11.0 years and 51% were males. Only 30% consulted with a physician for their HF within 2 weeks post ED visit. By 4 weeks, 51% consulted a physician. Over the 6 month follow-up, 25% returned to the ED, 23% were hospitalized, and 13.6% died. Patients who consulted a physician within 2 weeks of ED discharge had a non-significantly lower risk of adverse events (HR: 0.69, 95% CI 0.40-1.2). However, by 4 weeks, this relationship became statistically significant: patients who consulted a physician for their HF within 4 weeks were less likely to sustain an adverse event (HR: 0.59, 95% CI 0.36-0.97). In addition to late clinical follow up, factors associated with a higher risk of adverse event included worse Minnesota Score, HF with systolic dysfunction and previous myocardial infarction. CONCLUSION: Prompt follow-up post ED visit for HF is associated with lower risk for major adverse event. Adherence to current CCS benchmarks is crucial. There is an urgent need to improve the rate of medical consultation within 2 to 4 weeks following ED visit for patients with HF. Canadian Institutes of Health Research (CIHR)

Quality of life protocol in the early asthma diagnosis in children

Asthma is considered an important problem in children and influences on their everyday functioning. This study was concerned with the impact of asthma on the health-related quality of life (HRQOL) of newly recognized pediatric asthma patients and their parents. Patients were identified by a general respiratory survey. HRQOL was assessed by self-report measures: disease-specific questionnaire for children, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) and generic for parents-the Quality of Life in Child's Chronic Disease Questionnaire (QLCCDQ). Twenty-nine newly diagnosed asthmatic children aged 7-11 years (mean age = 8.6; SD = 1.4) were identified from a population-based respiratory health survey. The most impaired HRQOL domains differed in parents and children. In children, activity limitation was the most impaired; however in parents, emotional functioning and symptom perception domains were most impaired. There were no statistically significant differences in patient and parental HRQOL observed in either the group where symptoms were present or in the group were symptoms were not present. Baseline spirometry showed correlation for FEV(1)%FVC and PAQLQ symptom domain (r = 0.42). Exercise test showed correlations between FEV(1)%FVC and QLCCDQ emotional domain (r = 0.7); MEF 25-75% and family roles (r = 0.81), as well as social functioning (r = 0.81). Activity limitation on the PAQLQ correlated with the MEF 25-75% (r = 0.44) and PEF (r = 0.55). HRQOL newly recognized children with asthma and their parents does not correlate closely with clinical status. Patient and parental HRQOL should be considered as independent dimensions.

P03-168 - Quality of life and stress coping regarding people with psychiatric disorders in a one-year training

ObjectivesEvaluation of QOL, stress and coping strategies of people with psychiatric disorders after a one-year training course for social and occupational reintegration.MethodsThe main elements of the study focused on the SVF 120 (Stress Processing Questionnaire) and PLC (Quality of Life with Chronic Disease questionnaire).ResultsIn total a number of 20 people were enrolled in the study. Mean age of the participants was 33.4 years. The reintegration programme showed a retention rate of 100%. The PLC questionnaire showed no statistically significant results (p&gt;0.050). The SVF 120 showed a slightly better score after one year regarding social encapsulating (p= 0.056) and trivializing (p = 0.021). After the one-year training course 60% of the participants could be reintegrated in an occupational activity and 40% could achieve a better social status.ConclusionsOur results showed that participant of the programme used stress coping strategies morte than before the course. Reintegration data make clear that training courses of people with psychiatric disorders can achieve valuable results.

Development, evaluation and validation of a new instrument for measurement quality of life in the parents of children with chronic disease

BackgroundChildhood chronic disease may affect patients' and their family's functioning. Particularly parents, who play an important role in cooperation between patient and health care professionals, report impaired health - related quality of life (HRQOL). The aim of this study was development, evaluation and validation of a new instrument: Quality of Life in a Child's Chronic Disease Questionnaire (QLCCDQ). The questionnaire is addressed to parents of children with a chronic disease.MethodsStudy design included semi structured interview and qualitative study, which allowed to identify most troublesome problems. Following the results the questionnaire was developed, which consists of 15 questions and covers domains - emotions, patients -perceived symptoms, roles limitations. An observational study involving parents of asthma and diabetes children was conducted to assess the psychometric characteristics of the measure. Psychometric testing was based on the reliability of defined subscales, construct validity, reproducibility assessment, as well as comparison between stable/unstable disease stages and parents of healthy children.ResultsMost troublesome concerns for parents of child with chronic disease included emotional distress and feeling depressed due to child's disease, avoiding social interactions due to child's disease or symptoms. 98 parents of children with asthma or insulin - depended diabetes participated in the psychometric testing of QLCCDQ. Internal consistency reliability for the defined subscales ranged between 0.77 and 0.93. Reproducibility based on the weighted kappa coefficients showed expected level of agreement and was almost perfect in case of 8 questions, substantial for 5 questions and moderate for 2 questions. QLCCDQ demonstrated very good construct validity - all subscales showed statistically significant correlations ranging from 0.4 to 0.9. QLCCDQ scores differed significantly by clinical status - parents of children qualified as stable presented higher scores in most subscales in comparison to parents of children with unstable disease.ConclusionsThe QLCCDQ shows good internal consistency, test-retest reliability, and construct validity. The questionnaire may be useful in helping to understand the impact of chronic child's disease on parental perception of health outcomes.