ObjectiveAcademic investigation of thousands of children who claim past-life memories has been developed worldwide for five decades. However, despite the scientific and clinical significance of this substantial body of research, most clinicians and scientists are not aware of it. This study aims to report a case of a child who claimed memories that match his deceased granduncle's life and to perform a literature review of the main characteristics and implications of children's past-life claims. MethodWe investigated the case through interviews with the child and first-hand witnesses, and conducted a documental analysis to verify possible associations between the child's statements and facts from the deceased's life. We also performed a CT scan of the child's skull to verify possible associations between anatomical features and a fatal wound from the alleged previous life. ResultsThe child presented most key features typical of such cases of claimed past-life memories. He made 13 statements about the previous life; nine were correct (e.g., the mode of death and a toy the granduncle had) and four were undetermined. The child demonstrated eight unusual behaviors that matched the previous personality´s habits, interests, and manners. The child has a birth defect (a rare occipital concavity) that is compatible with the firearm injury that caused the death of his uncle. ConclusionsThe characteristics of the reported case fit the cross-cultural patterns of children who claim past-life memories, and it has scientific and clinical implications that need to be better known and investigated.