Oil Chemistry Research Articles

Distribution and origin of higher diamondoids in the ultra-deep Paleozoic condensates of the Shunbei oilfield in the Tarim Basin, NW China

Higher diamondoids in the condensates of the Shunbei oilfield were analyzed using GC–MS. The findings indicate that the condensates in the Shunbei oilfield were subjected to a superimposed effect of secondary alterations, including biodegradation, hydrothermal alteration, evaporative fractionation, cracking, and TSR. High local concentrations of thiaadamantanes in oil may result from the interaction of H2S, derived from Cambrian TSR, with Ordovician hydrocarbons, influenced by hydrothermal activities. Comprehensive analysis shows that TSR is local and limited in Ordovician reservoirs in the Shunbei oilfield and has no significant impact on oil chemistry. Comparative studies indicate that the diamondoid concentrations in condensates from the Shunbei oilfield have not been significantly impacted by biodegradation and evaporative fractionation. Parameters related to diamantanes can effectively characterize their geochemical characteristics and secondary alteration. A multi-parameter correlation heat map suggests that higher diamondoids in the condensates of the Shunbei oilfield are not due to high thermal evolution but have been altered by hydrothermal activity. The hydrothermal activity promotes the formation of higher diamondoids in the condensate. The higher diamondoids that are formed by hydrothermal activity offer a new perspective for studying hydrothermal processes. Additionally, this aids in studying the organic-inorganic interactions of ultra-deep organic fluids with their mineralogical and aqueous environments.

Artemisia pallens Wall. ex. DC: A comprehensive review

Davana (Artemisia pallens Wall. ex DC) is a well-known and precious essential oil-bearing plant under the family Compositae (Asteraceae). It is an erectly grown herbaceous plant exclusively cultivated as a short-term crop in south India during winter. It is distributed in the northern hemisphere in subtropical Africa, South Africa, West America, and South America; however, it is indigenous to southern India. The yearly productivity of davana oil typically falls between 8 to 10 tones. Davana oil is mainly used to flavor pastries, cakes, tobacco, and some beverages. It consists of diverse phyto-molecules and is an important and unique commodity in the fragrance, flavor, and liquor industries. It has excellent biological potential and contains volatile and nonvolatile constituents such as terpenoids, flavonoids, and alkaloids, which have high pharmacological values. Several investigations have focused on validating the importance of chemical constituents and the biological efficacy of essential oils and various extracts in multiple industries. The review focuses on the complete agronomic practices, botany, breeding, biotechnology, and chemistry of davana essential oil (DEO), viz, volatile and nonvolatile constituents, phytomedicinal and pharmacological properties, which may help researchers achieve their future goals for approaching its industrial or commercial viability as a natural product ingredient.

Soy‐based polyester: Sustainable solutions for emerging materials

AbstractInnovative and renewable polymers and additives are the focus of increased research due to public and environmental pressure. There has been a recent uptick in interest from scientists in biobased “green” plasticizers that can be covalently bonded to replace harmful and migratory phthalate‐based plasticizers. Vegetable oils (VOs) are one of the biosources, as they are both plentiful and sustainable. This review aims to highlight the synthesis methods for soy‐based polyesters. Therefore, the chemistry of soybean oil as a polymeric material and its role in the synthesis of polyesters derived from soybeans are the primary topics of this review. This review covers the many ways in which soybean oil and its derivatives can be used to synthesize polyester, either directly or indirectly.Highlights The need for sustainable polymers is explored. Soybean oil‐based polyesters are covered. Modification and chemistry to convert soybean oil into polyester are described. Applications of soybean‐based polyesters are provided.

A Study on One-Time Inspection for Aging Management of Operating Nuclear Power Plants

One-time inspection is used to confirm the effectiveness of nuclear power plant aging management programs such as water chemistry, fuel oil chemistry, and selective leaching program that is designed to prevent or minimize aging degradation during the plant operation. This paper represents one-time inspection experience of selected components and susceptible locations within the scope of water chemistry and fuel oil chemistry aging management programs. Prior to performing one-time inspection, sample sizes of components to be inspected were determined based on combination of materials, environment and aging effect. Examination techniques and relevant operating experience were analysed to obtain technical basis for further implementation of one-time inspection aging management programs. Existing correlation curves between sample size and total population number were reviewed to prepare further inspections for entire operating plants and ensure safety level of components subject to one-time inspection program.

Registration of FloRun ‘T61’ peanut

AbstractFloRun ‘T61’ (Reg. no. CV‐159, PI 700039) is a high‐oleic, runner market‐type peanut (Arachis hypogaea L. subsp. hypogaea var. hypogaea) cultivar developed by the University of Florida Agricultural Experiment Station, North Florida Research and Education Center, near Marianna, FL. It resulted from a cross between ‘Georiga‐06G’ and a University of Florida Agricultural Experiment Station experimental line ‘UF12302’ and was tested under the experimental designation UF11 × 41‐HO1‐4‐1‐1 and was approved for release in 2021. FloRun ‘T61’ has a semi‐prostrate growth habit, with moderate vine size and a prominent center stem. The seed is smaller than seed of Georgia‐06G but larger than FloRun ‘331’ (67.3 g vs. 64.6 g; P < 0.0001). It yielded similarly to FloRun ‘331’ over the 4‐year period of 2017–2020 in three Florida locations (7862 kg ha−1 vs. 8068 kg ha−1), and its pod yield was slightly greater than Georgia‐06G during the 5‐year period of 2016–2020 (7680 kg ha−1 vs. 7273 kg ha−1; P = 0.0137). The total sound mature kernel grade of FloRun ‘T61’ was slightly greater than that of FloRun ‘331’ (78.6% vs. 77.7%, P < 0.025) but was similar to the total sound mature kernel grade of Georgia‐06G. FloRun ‘T61’ has high oleic oil chemistry composed of 77.1% oleic fatty acid versus 58.7% for Georgia‐06G in 2020 (P < 0.001) and 79.2% in 2021 compared with 65.7% for Georgia‐06G (P < 0.001). Over 5 years, the spotted wilt ratings of FloRun ‘T61’ (2.5) were less than for FloRun ‘331’ (4.8; P < 0.01). In summary, FloRun ‘T61’ combines excellent yield, grade, disease, and oil chemistry traits and should be beneficial to farmers and manufacturers of peanut foods.

Exploring the Volatile Composition and Antibacterial Activity of Edible Flower Hydrosols with Insights into Their Spontaneous Emissions and Essential Oil Chemistry.

In the circular economy framework, hydrosols, by-products of the essential oil industry, are gaining attention for their potential in waste reduction and resource reuse. This study analyzed hydrosols from six edible flowers, investigating their chemical composition (VOC-Hyd) and antibacterial properties alongside volatile organic compounds of fresh flowers (VOC-Fs) and essential oils (EOs). Antirrhinum majus exhibited ketones as major VOC-Fs (62.6%) and VOC-Hyd (41.4%), while apocarotenoids dominated its EOs (68.0%). Begonia cucullata showed alkanes (33.7%) and aldehydes (25.7%) as primary VOC-Fs, while alkanes were prevalent in both extracts (65.6% and 91.7% in VOC-Hyd and in EOs, respectively). Calandula officinalis had monoterpenoids in VOC-Fs and VOC-Hyd (89.3% and 49.7%, respectively), while its EOs were rich in sesquiterpenoids (59.7%). Dahlia hortensis displayed monoterpenoid richness in both VOC-Fs and extracts. Monocots species' VOC-Fs (Polianthes tuberosa, Tulbaghia cominsii) were esters-rich, replaced by monoterpenoids in VOC-Hyd. P. tuberosa EO maintained ester richness, while T. cominsii EOs contained a significant percentage of sulfur compounds (38.1%). Antibacterial assays indicated comparable minimum inhibitory concentration profiles across VOC-Hyd: B. calcullata and P. tuberosa against Staphylococcus aureus and Salmonella enterica ser. typhimurium, T. cominsii against Escherichia coli and S. enterica, A. majus and C. officinalis against S. aureus, and D. hortensis against S. enterica.

Butylated Hydroxytoluene (BHT) Protects SH-SY5Y Neuroblastoma Cells from Ferroptotic Cell Death: Insights from In Vitro and In Vivo Studies.

Ferroptosis is a special kind of programmed cell death that has been implicated in the pathogenesis of a large number of human diseases. It involves dysregulated intracellular iron metabolism and uncontrolled lipid peroxidation, which together initiate intracellular ferroptotic signalling pathways leading to cellular suicide. Pharmacological interference with ferroptotic signal transduction may prevent cell death, and thus patients suffering from ferroptosis-related diseases may benefit from such treatment. Butylated hydroxytoluene (BHT) is an effective anti-oxidant that is frequently used in oil chemistry and in cosmetics to prevent free-radical-mediated lipid peroxidation. Since it functions as a radical scavenger, it has previously been reported to interfere with ferroptotic signalling. Here, we show that BHT prevents RSL3- and ML162-induced ferroptotic cell death in cultured human neuroblastoma cells (SH-SY5Y) in a dose-dependent manner. It prevents the RSL3-induced oxidation of membrane lipids and normalises the RSL3-induced inhibition of the intracellular catalytic activity of glutathione peroxidase 4. The systemic application of BHT in a rat Alzheimer's disease model prevented the upregulation of the expression of ferroptosis-related genes. Taken together, these data indicate that BHT interferes with ferroptotic signalling in cultured neuroblastoma cells and may prevent ferroptotic cell death in an animal Alzheimer's disease model.

STUDIES OF OILCONTAMINATED SOILS AND FORWARDLOOKING APPROACHES TO THEIR REMEDIATION

Milestones in the study of oilcontaminated soils at the Faculty of Soil Science for 50 years of its foundation are discussed from the prospects for the development of environmental regulation and new technologies of soil reclamation. The development of a methodological framework for the determination of oil and petroleum hydrocarbons in soils, studies of soil properties, the chemistry of oil and its components in soil and adjacent media are shown. The development of legislation on the rationing of petroleum hydrocarbons in soils is given, including the important role of the staff of Faculty of Soil Science of Moscow State University in the work out of a number of regional standards for the permissible residual content of petroleum hydrocarbons in soils is noted. The approaches to ecological rationing of oil and petroleum hydrocarbons in soils are proposed, in the aspects of natural climatic zones and the type of landuse. The importance of improving the regulatory and methodological framework and continuing work in this direction is emphasized. The necessity of research at developing technologies for reclamation of oilcontaminated lands and special use of oilcontaminated waste is indicated.

Gas chromatography/mass spectrometry analysis and uv absorptivity of bio-oils extracted from some locally grown plant seeds in nothern Nigeria

Oils play vital roles in various ramifications including health, and food industries. Oils which are components of plant seeds can be extracted using various extraction techniques. This research is an exposition into the chemistry of oils with possible repositioning for purposeful use in the cosmetic, pharmaceutical, and food industries especially as sunscreen. In this work, oils were extracted from nine different seeds and subjected to gas chromatography coupled to mass spectrometry, and Ultraviolet analysis. The extraction method adopted in this work shows that 5 out of the 9 seeds have a relatively high percentage yield ranging from 20.9 to 36.8 % which indicates their potential for use in commercial quantity. The GC- MS analysis shows that (Z, Z)- 9, 12-Octadecadienoic acid is the most abundant components of all the oil samples. n-Hexadecanoic acid and cis-Vaccenic acid are the major constituents of Swietenia macrophylla (mahogany) seed oil. The lead components in the oil samples are usually responsible for their physico-chemical and Ultraviolet interactivities. All the samples were found to have adequate absorbance for Ultraviolet radiation ranging from Ultraviolet C to Ultraviolet A region. Citrullus lanatus, Hyptis spicigera, and Swietenia macrophylla (mahogany) have the highest absorbance ranges of 1.394–1.718, 1.449 to 1.70,2 and 1.402 to 1.711 respectively at Ultraviolet A region. The finding shows that all the samples have the ability to protect the skin from Ultraviolet radiation when expose to the sun, whereas only Citrullus lanatus, Hyptis spicigera and Swietenia macrophylla (mahogany) have the potentials for use as sunscreen with high sun protection factor. Further studies on the antimicrobial activities, cosmeceutical and nutraceutical potentials of the various components of these samples are encouraged.

Antimicrobial Activity of Frankincense (Boswellia sacra) Oil and Smoke against Pathogenic and Airborne Microbes.

As they continuously evolve, plants will remain a renewable source for antimicrobial compounds. Omani frankincense is produced by B. sacra trees and is graded into Hojari, Nejdi, Shazri or Sha'bi. Air can be a source for pathogenic or food spoilage microbes; thus, inactivating airborne microbes is necessary in environments such as food and animal production areas. This study investigated the antimicrobial activity and the chemistry of steam-distilled oils of Hojari and Sha'bi grades. It also analyzed the antimicrobial activity of frankincense smoke and the size of its solid particles. Chemical analysis was performed using gas chromatography mass spectrometry (GC-MS). The antimicrobial activity of the oils against Staphylococcus aureus (NCTC 6571), Bacillus spp., Escherichia coli (NCTC 10418), Pseudomonas aeruginosa (NCTC 10662), Saccharomyces cerevisiae, Candida albicans, Aspergillus flavus, Aspergillus ochraceus, Aspergillus niger, Penicillium citrinum, Alternaria alternata and Fusarium solani was determined using well diffusion and micro-well dilution methods. A microscopic technique was used to determine the size of frankincense smoke solid particles. Microbes were exposed to frankincense smoke to test their susceptibility to the smoke. Hojari and Sha'bi oils were similar in composition and contained monoterpenes and sesquiterpenes. The Hojari and the Sha'bi oils possessed broad spectrum antimicrobial activity. The largest growth inhibition zones were obtained with S. cerevisiae and F. solani. An MIC of 1.56% (v/v) was found with E. coli, S. cerevisiae and F. solani. Frankincense smoke contained fine irregular solid particles with a diameter range of 0.8-2287.4 µm, and thus may pose a health risk to susceptible individuals. The smoke had potent antimicrobial activity against S. aureus, E. coli, and airborne bacteria, yeast and mold, with a maximum inhibition of 100%. It was concluded that Hojari and Sha'bi frankincense oils and smoke had significant antimicrobial activity that can be exploited in controlling human, animal and plant pathogenic microbes.

Quantifying Ozone-Dependent Emissions of Volatile Organic Compounds from the Human Body.

Ozone reactions on human body surfaces produce volatile organic compounds (VOCs) that influence indoor air quality. However, the dependence of VOC emissions on the ozone concentration has received limited attention. In this study, we conducted 36 sets of single-person chamber experiments with three volunteers exposed to ozone concentrations ranging from 0 to 32 ppb. Emission fluxes from human body surfaces were measured for 11 targeted skin-oil oxidation products. For the majority of these products, the emission fluxes linearly correlated with ozone concentration, indicating a constant surface yield (moles of VOC emitted per mole of ozone deposited). However, for the second-generation oxidation product 4-oxopentanal, a higher surface yield was observed at higher ozone concentrations. Furthermore, many VOCs have substantial emissions in the absence of ozone. Overall, these results suggest that the complex surface reactions and mass transfer processes involved in ozone-dependent VOC emissions from the human body can be represented using a simplified parametrization based on surface yield and baseline emission flux. Values of these two parameters were quantified for targeted products and estimated for other semiquantified VOC signals, facilitating the inclusion of ozone/skin oil chemistry in indoor air quality models and providing new insights on skin oil chemistry.

Theoretical Interpretation of pH and Salinity Effect on Oil-in-Water Emulsion Stability Based on Interfacial Chemistry and Implications for Produced Water Demulsification

The petroleum industry produces thousands of barrels of oilfield waters from the initial stage driven by primary production mechanisms to the tertiary stage. These produced waters contain measurable amounts of oil-in-water emulsions, the exact amounts being determined by the chemistry of the crude oil. To meet strict environmental regulations governing the disposal of such produced waters, demulsification to regulatory permissible levels is required. Within the electric double layer theory, coupled with the analytical solutions to the Poisson–Boltzmann Equation, continuum electrostatics approaches can be used to describe the stability and electrokinetic properties of emulsions. In the literature, much of the surface charge density and zeta potential relationship to emulsion stability has been confined to systems with less salinity. In this paper, we have exploited the theoretical foundations of the electric double layer theory to carry out theoretical evaluations of emulsion salinity based on zeta potential and surface charge density calculations. Most importantly, our approaches have enabled us to extend such theoretical calculations to systems of the higher salinity characteristic of oil-in-water emulsions found in oilfield-produced waters, based on crude oil samples from the literature with varying surface chemistry. Moreover, based on the definition of acid crude oils, our choice of samples represents two distinct classes of crude oils. This approach enabled us to evaluate the stability of emulsions associated with these produced oilfield waters in addition to predicting the potential of demulsification using demulsifiers. Given that the salinity range of this study is that encountered with the vast majority of produced oilfield waters, the findings from our theoretical predictions are perfect guides as far as emulsion stability is concerned.

Essential Oils: Chemistry and Pharmacological Activities.

In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical aspects with the bioactivity of these products. Next, the antioxidant, anti-inflammatory, antitumor, and antimicrobial activities are discussed. The mechanisms of action against various types of viruses are also addressed. The data show that the multiplicity of pharmacological properties of essential oils occurs due to the chemical diversity in their composition and their ability to interfere with biological processes at cellular and multicellular levels via interaction with various biological targets. Therefore, these natural products can be a promising source for the development of new drugs.

HYDROGENATION TECHNOLOGY AND CHEMISTRY OF COTTONSEED OIL AND FATS

The presented research describes the hydrogenation technology and the chemistry of vegetable oils and fats using powder and stationary catalysts. The hydrogenation technology process includes various equipment and materials, i.e., equipment for hydrogenation, laboratory flow reactor, autoclave for hydrogenation on powder nickel-copper catalyst, hydrogenation catalysts, and selection of alloy stationary catalysts and their structure. The hydrogenation process includes selecting alloy nickelaluminum catalyst promoters, measuring the viscosity of hydrogenated fat, using static catalysts as forcontacts, kinetic regularities of cotton oil hydrogenation with new modifications of nickel-copperaluminum alloy promoted catalysts, and reception of food hydrogenated fat by consecutive hydrogenation of cotton oil on powder and stationary catalysts. Modifying immobile nickel-copperaluminum alloy catalysts also evolved with the addition of vanadium, rhodium, and palladium in the hydrogenation process. The cotton oil pre-contact hydrogenation on stationary and powder nickelcopper catalysts is a novel development. It ensures an increase in the physiological and nutritional value of margarine products based on hydrogenated food fat. Studying the influence of technological regimes of cotton oil hydrogenation on new modifications of stationary nickel-copper-aluminum promoted catalysts commenced. The obtained results established the technological parameters for acquiring food and confectionery salons by combining stationary and suspended catalysts. Likewise, a combination of stationary and suspended catalysts has instituted the industrial parameters for the production of food and confectionery salons based on the effects of technological regimes (temperature, pressure, oil, and hydrogen supply rates) of cottonseed oil hydrogenation on new modifications of stationary nickel-copper-aluminum promoted catalysts.

Chemistry and Insecticidal Activity of Essential Oils against Trogoderma granarium Larvae

Chemistry and Insecticidal Activity of Essential Oils against Trogoderma granarium Larvae

Emerging Chemical Methods for Petroleum and Petroleum-Derived Dissolved Organic Matter Following the Deepwater Horizon Oil Spill.

Despite the fact that oil chemistry and oils spills have been studied for many years, there are still emerging techniques and unknown processes to be explored. The 2010 Deepwater Horizon oil spill in the Gulf of Mexico resulted in a revival of oil spill research across a wide range of fields. These studies provided many new insights, but unanswered questions remain. Over 1,000 journal articles related to the Deepwater Horizon spill are indexed by the Chemical Abstract Service. Numerous ecological, human health, and organismal studies were published. Analytical tools applied to the spill include mass spectrometry, chromatography, and optical spectroscopy. Owing to the large scale of studies, this review focuses on three emerging areas that have been explored but remain underutilized in oil spill characterization: excitation-emission matrix spectroscopy, black carbon analysis, and trace metal analysis using inductively coupled plasma mass spectrometry.

Evaluating the Potential of Boswellia rivae to Provide Sustainable Livelihood Benefits in Eastern Ethiopia.

Frankincense is an oleo-gum-resin collected from wild Boswellia spp. trees, and widely used in perfumery, cosmetics, aromatherapy, incense, and other industries. Boswellia rivae, growing in Ethiopia, Somalia, and Kenya, is one source of frankincense, but is little-commercialized compared to species such as B. sacra, B. frereana, and B. papyrifera. In this study, we examine the resin essential oil chemistry and harvesting systems of B. rivae in order to evaluate its potential for increased trade and potential positive livelihood benefits. Boswellia rivae produces an essential oil rich in α-thujene (0.1-12.4%), α-pinene (5.5-56.4%), β-pinene (0.3-13.0%), δ-3-carene (0.1-31.5%), p-cymene (1.4-31.2%), limonene (1.8-37.3%), β-phellandrene (tr-5.6%), trans-pinocarveol (0.1-5.0%), trans-verbenol (0.1-11.2%), and trans-β-elemene (0-5.7%), similar to major commercial species, although it is difficult to detect mixing of B. rivae and Commiphora africana resins from chemistry alone. The B. rivae trees are not actively tapped, so resin collection has a neutral impact on the health of the trees, and resin production is unaffected by drought. Consequently, collecting resins acts as a key income supplementing livestock herding, as well as a safety net protecting pastoral communities from the severe negative effects of climate change-exacerbated drought on livestock. Therefore, Boswellia rivae is well positioned chemically, ecologically, and socially to support expanded trade.

Microbial responses to increased salinity in oiled upper tidal shorelines

The microbial degradation of crude oil stranded on seashores is usually much slower than that of dispersed oil at sea. This is usually attributed to nutrient limitation and higher oil concentrations on beaches than in dispersed plumes, in addition to the low moisture content and transient hypersaline conditions of the upper intertidal and supratidal zones. Here, we investigated the effect of hypersaline conditions, oil concentration, and nutrient limitation on the hydrocarbonoclastic activity. Beach sand, with oil concentrations of 1 and 10 mL/kg, was infiltrated with seawater at salinities of 30, 90, and 160 g/L to 20% saturation, with and without the addition of nutrients. Oil chemistry, 16 S rRNA gene amplicon, and metagenomic sequencing analyses were conducted every 30 days for 180 days. The biodegradation of aromatic hydrocarbons was much slower at higher salinities, while that of alkanes was not noticeably affected, and the addition of nutrients only marginally enhanced the biodegradation of hydrocarbons. The relative abundance and diversity of genera varied substantially with the increase in pore water salinity, whereby halophilic hydrocarbon-degrading microorganisms, particularly in the Marinobacter genus, were significantly abundant only under hypersaline conditions. The enzymes were considerably less abundant at high salinities, mainly for those associated to aromatic hydrocarbon degradation pathways. Consequently, occasional inundation of the upper parts of oiled sandy beaches with seawater to decrease the pore water salinity and reseed the contaminated region with indigenous hydrocarbon degraders, along with the concomitant addition of fertilizers, could be a suitable, non-destructive, and inexpensive response tool for enhancing the biodegradation of beached crude oil, particularly that of the aromatic fraction.

Conventional vs. Microwave-Assisted Hydrodistillation: Influence on the Chemistry of Sea Fennel Essential Oil and Its By-Products.

The main objectives of this study were to investigate the effects of the applied essential oil (EO) isolation method, conventional hydro-distillation (HD), and microwave-assisted hydro-distillation (MHD) on the chemical profile of sea fennel (Crithmum maritimum L.) essential oil and to investigate the main constituents present in the liquid by-products of EOs isolation (hydrolate and residual wastewater). Headspace-solid phase microextraction (HS-SPME) was used to isolate hydrolate components, while gas chromatography coupled with mass spectrometry (GC-MS) was used to detect and analyse the chemical constituents of the essential oils and hydrolates. The phenolic composition of the wastewater extracts was analysed by high performance liquid chromatography (HPLC). The EO obtained by MHD had a higher yield of limonene and sabinene. The chemical composition of the hydrolates differed from the EO compositions. The content of terpinen-4-ol in the MHD hydrolate was higher, while several compounds were detected in relatively high proportions only in the HD hydrolate. MHD also resulted in a higher phenolic content of the wastewater, where an increase in the concentration of chlorogenic acid was also observed. It can be concluded that the isolation method had a great influence on the profile of sea fennel EOs, especially on their corresponding hydrolates and residual wastewater extracts. Due to their valuable chemical composition, these by-products can be a cost-effective source of bioactive compounds that have great potential for use in various industries.

Chemistry and Bioactivity of Croton Essential Oils: Literature Survey and Croton hirtus from Vietnam.

Using essential oils to control vectors, intermediate hosts, and disease-causing microorganisms is a promising approach. The genus Croton in the family Euphorbiaceae is a large genus, with many species containing large amounts of essential oils, however, essential oil studies are limited in terms of the number of Croton species investigated. In this work, the aerial parts of C. hirtus growing wild in Vietnam were collected and analyzed by gas chromatography/mass spectrometry (GC/MS). A total of 141 compounds were identified in C. hirtus essential oil, in which sesquiterpenoids dominated, comprising 95.4%, including the main components β-caryophyllene (32.8%), germacrene D (11.6%), β-elemene (9.1%), α-humulene (8.5%), and caryophyllene oxide (5.0%). The essential oil of C. hirtus showed very strong biological activities against the larvae of four mosquito species with 24 h LC50 values in the range of 15.38-78.27 μg/mL, against Physella acuta adults with a 48 h LC50 value of 10.09 μg/mL, and against ATCC microorganisms with MIC values in the range of 8-16 μg/mL. In order to provide a comparison with previous works, a literature survey on the chemical composition, mosquito larvicidal, molluscicidal, antiparasitic, and antimicrobial activities of essential oils of Croton species was conducted. Seventy-two references (seventy articles and one book) out of a total of two hundred and forty-four references related to the chemical composition and bioactivity of essential oils of Croton species were used for this paper. The essential oils of some Croton species were characterized by their phenylpropanoid compounds. The experimental results of this research and the survey of the literature showed that Croton essential oils have the potential to be used to control mosquito-borne and mollusk-borne diseases, as well as microbial infections. Research on unstudied Croton species is needed to search for species with high essential oil contents and excellent biological activities.