Preface Introduction Part I. Background Material: 1. Concepts from physical chemistry 2. Conventions and calculations for biochemical systems 3. Chemical kinetics and transport processes Part II. Analysis and Modeling of Biochemical Systems: 4. Enzyme-catalyzed reactions 5. Biochemical signaling modules 6. Biochemical reaction networks 7. Coupled biochemical systems and membrane transport Part III. Special Topics: 8. Spatially distributed systems and reaction-diffusion modeling 9. Constraint-based analysis of biochemical systems 10. Biomacromolecular structure and molecular association 11. Stochastic biochemical systems and the chemical master equation 12. Appendix: the statistical basis of thermodynamics Bibliography Index.