In this study, we analyze the vacuum stability of the economical 331 model at the one-loop level using the renormalization group equations and a single-scale renormalization method. By integrating these equations, we determine stability conditions up to the Planck scale, incorporating constraints from recent experimental data on new Higgs-like bosons, charged scalars, and charged and neutral gauge bosons. Our analysis uncovers intriguing relations between the mass of the heaviest scalar and the masses of exotic quarks, in order to ensure stability of the model up to the Planck scale. For the 331 energy scale used in this work, 18 TeV, we find an upper bound on the heaviest quark mass of the model, which is not so distant from future LHC runs, serving as bounds to be searched. Additionally, we explore relations between the scalar couplings coming stability and perturbativity conditions. These impose unprecedented constraints on the economical 331 model.
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