An elegant and fruitful way to bring harmonic analysis into the theory of orthogonal polynomials and special functions, or to associate certain Banach algebras with orthogonal polynomials satisfying a specific but frequently satisfied nonnegative linearization property, is the concept of a polynomial hypergroup. Polynomial hypergroups (or the underlying polynomials, respectively) are accompanied by L1-algebras and a rich, well-developed and unified harmonic analysis. However, the individual behavior strongly depends on the underlying polynomials. We study the associated symmetric Pollaczek polynomials, which are a two-parameter generalization of the ultraspherical polynomials. Considering the associated L1-algebras, we will provide complete characterizations of weak amenability and point amenability by specifying the corresponding parameter regions. In particular, we shall see that there is a large parameter region for which none of these amenability properties hold (which is very different to L1-algebras of locally compact groups). Moreover, we will rule out right character amenability. The crucial underlying nonnegative linearization property will be established, too, which particularly establishes a conjecture of R. Lasser (1994). Furthermore, we shall prove Turán’s inequality for associated symmetric Pollaczek polynomials. Our strategy relies on chain sequences, asymptotic behavior, further Turán type inequalities and transformations into more convenient orthogonal polynomial systems.