Changes In Relative Amplitudes Research Articles

Observing an expert's action swapped with an observer's face increases corticospinal excitability during combined action observation and motor imagery.

This study aimed to examine whether observing an expert's action swapped with an observer's face increases corticospinal excitability during combined action observation and motor imagery (AOMI). Twelve young males performed motor imagery of motor tasks with different difficulties while observing the actions of an expert performer and an expert performer with a swapped face. Motor tasks included bilateral wrist dorsiflexion (EASY) and unilateral two-ball rotating motions (DIFF). During the AOMI of EASY and DIFF, single-pulse transcranial magnetic stimulation was delivered to the left primary motor cortex, and motor-evoked potentials (MEPs) were obtained from the extensor carpi ulnaris and first dorsal interosseous muscles of the right upper limb, respectively. Visual analogue scale (VAS) assessed the subjective similarity of the expert performer with the swapped face in the EASY and DIFF to the participants themselves. The MEP amplitude in DIFF was larger in the observation of the expert performer with the swapped face than that of the expert performer (P = 0.012); however, the corresponding difference was not observed in EASY (P = 1.000). The relative change in the MEP amplitude from observing the action of the expert performer to that of the expert performer with the swapped face was positively correlated with VAS only in DIFF (r = 0.644, P = 0.024). These results indicate that observing the action of an expert performer with the observer's face enhances corticospinal excitability during AOMI, depending on the task difficulty and subjective similarity between the expert performer being observed and the observer.

Chronological features of Heinrich Stadial 2 based on a high-resolution analysis of δ18O stalagmite records from China, and possible links to changes in Atlantic Meridional Overturning Circulation

The Heinrich Stadial 2 (HS2) event is poorly defined in the Greenland δ18O ice core record; however, it can be identified in stalagmite records from China. In this paper, we reconstruct an absolutely-dated and high-resolution calcite δ18O record from Shima Cave, central China, covering the interval from 26.0 to 23.9 ka BP, with a temporal resolution of ~16 years. By integrating our newly reported record with all available δ18O records of Marine Isotope Stage 2 from China, which are securely 230Th/U-dated, we calculate the timing of the onset, termination and duration of HS2. The statistical results show that the prominent HS2a phase started at ~24.4 ± 0.1 ka BP and ended at ~23.6 ± 0.1 ka BP, lasting approximately 0.8 ± 0.3 ka. If the onset of the Dansgaard-Oeschger 2 event in the Greenland δ18O record is synchronous with the termination of HS2a, then the GICC05 chronology should be adjusted by +230 years to align it with stalagmite results. Further investigation of HS2 shows that Chinese cave records exhibit a distinct two-fold structure, corresponding to HS2a and HS2b, as observed in marine sediment cores, particularly those recovered around the Atlantic Ocean. These records show comparable changes in relative amplitudes during the HS2a and HS2b phases, which could possibly be related to different weakening episodes in the Atlantic Meridional Overturning Circulation.

A rail defect detection system based on laser Doppler vibrometer measurements

This paper aims at introducing a non-contact rail damage detection system based on laser Doppler vibrometer (LDV) measurements. Specifically, the system consists of two LDVs mounted on a rail car, to record the waves induced on the rail head by random rail-wheel interaction forces.The developed damage detection framework associated with the system is based on a multivariate analysis that combines damage features which are based on the relative change in amplitude of the LDV signals that are caused by both reflected and transmitted waves. In this study, the damage detection system is introduced and validated through field tests which were carried out at the Transportation Technology Center (TTC) in Pueblo, CO. In these tests, a rail car installed with the damage detection system traveled over a track that consisted of a discontinuity in the rail (i.e., welded joint) at different speeds up to 48 km/h (30mph). Results show that the proposed system can identify the rail segment in which the propagating waves on the rail head are affected by the presence of the welded joint.

Modulation effect of mouse hippocampal neural oscillations by closed-loop transcranial ultrasound stimulation

Objective. Closed-loop transcranial ultrasound stimulation (TUS) can be applied at a specific time according to the state of neural activity to achieve timely and precise neuromodulation and improve the modulation effect. In a previous study, we found that closed-loop TUS at the peaks and troughs of the theta rhythm in the mouse hippocampus was able to increase the absolute power and decrease the relative power of the theta rhythm of local field potentials (LFPs) independent of the peaks and troughs of the stimulus. However, it remained unclear whether the modulation effect of this closed-loop TUS-induced mouse hippocampal neural oscillation depended on the peaks and troughs of the theta rhythm. Approach. In this study, we used ultrasound with different stimulation modes and durations to stimulate the peaks (peak stimulation) and troughs (trough stimulation) of the hippocampal theta rhythm. The LFPs in the area of ultrasound stimulation were recorded and the amplitudes and power spectra of the theta rhythm before and after ultrasound stimulation were analyzed. Main results. The results showed that (a) the relative change in amplitude of theta rhythm decreases as the number of stimulation trials under peak stimulation increases; (b) the relative change in the absolute power of the theta rhythm decreases as the number of stimulation trials under peak stimulation increases; (c) the relative change in amplitude of the theta rhythm increases nonlinearly with the stimulation duration (SD) under peak stimulation, and; (d) the relative change in absolute power exhibits a nonlinear increase with SD under peak stimulation. Significance. These results suggest that the modulation effect of closed-loop TUS on theta rhythm is dependent on the stimulation mode and duration under peak stimulation. TUS has the potential to precisely modulate theta rhythm-related neural activity.

Spatiotemporal characteristics of lower back muscle fatigue during a ten minutes endurance test at 50% upper body weight in healthy inactive, endurance, and strength trained subjects.

In modern developed societies, heavy physical demands are decreasing and getting replaced by longer periods of static, low-exertion activities such as sitting or standing. To counteract this lack of physical activity, more and more people are engaging in physical activity through exercise and training. Virtually opposite training modalities are endurance and strength. We asked if back muscle endurance capacity is influenced by training mode. 38 healthy male subjects (age range 19–31 years, mean age 22.6 years) were investigated: sedentary (Control, n = 12), endurance trained (ET, n = 13), and strength trained participants (ST, n = 13). They underwent a ten-minutes isometric extension task at 50% of their upper body weight. Surface EMG was measured in the low-back region utilizing quadratic 4*4 monopolar electrode montages per side. Relative amplitude and mean frequency changes were analysed with respect to electrode position and group during the endurance task. Eight ST subjects failed to complete the endurance task. Relative amplitude and frequency changes were largest in the ST group, followed by Control and ET groups (amplitude: F 6.389, p 0.004, frequency: F 11.741, p<0.001). Further, independent of group largest amplitude increase was observed for the most upper and laterally positioned electrodes. Mean frequency changes showed no systematic spatial distribution pattern. Although, in the light of an aging population, strength training has its merits our results question the functional suitability of frequent and isolated high-impact strength training for everyday endurance requirements like doing the dishes. Fatigue related amplitude elevations are systematically distributed in the back region, showing least fatigue signs for the most caudal and medial, i.e. the lumbar paravertebral region.

Feasibility evaluation of transtympanic laser stimulation of the cochlea from the outer ear.

Infrared laser stimulation has been studied as an alternative approach to auditory prostheses. This study evaluated the feasibility of infrared laser stimulation of the cochlea from the outer ear, bypassing the middle ear function. An optic fiber was inserted into the ear canal, and a laser was used to irradiate the cochlea through the tympanic membrane in Mongolian gerbils. A pulsed infrared laser (6.9 mJ/cm2) and clicking sound (70 peak-to-peak equivalent sound pressure level) were presented to the animals. The amplitude of the laser-evoked cochlear response was systematically decreased following insertion of a filter between the tympanic membrane and cochlea; however, the auditory-evoked cochlear response did not decrease. The filter was removed, and the laser-evoked response returned to around the original level. The amplitude ratio and the relative change in response amplitude before and during filter insertion significantly decreased as the absorbance of the infrared filter increased. These results indicate that laser irradiation could bypass the function of the middle ear and directly activate the cochlea. Therefore, laser irradiation from the outer ear is a possible alternative for stimulating the cochlea, circumventing the middle ear.

The Relationship Between “Large” Early/Fast VLF Events and Modal Propagation Nulls

Early/fast very low frequency (VLF) events evidence the direct impulsive coupling of lightning energy to the overlying mesosphere and lower ionosphere, and they are readily detected as rapid (<20 msec) changes to the amplitude and phase of VLF transmitter signals propagating within the Earth-ionosphere waveguide. Typical early/fast VLF events exhibit 0.1-1.0 dB amplitude changes, but can be smaller (<0.1 dB) or significantly larger (>10 dB). Large (>6 dB) early/fast events have not yet been satisfactorily simulated, and past work has suggested that large amplitude early/fast VLF events may only be detected when the receiver is located in a VLF propagation “null.” VLF propagation “nulls” result from the destructive interference of propagating waveguide modes, and they would result in deceptively large relative changes in field amplitude by reducing the magnitude of the ambient field, rather than by increasing the magnitude of the scattered field. In this paper, we present a new method to quantify the degree of destructive modal interference at the location of the VLF receiver, and we apply this method to analyze the impact of modal interference on the detected amplitude changes associated with 235 early/fast VLF events occurring over the Midwestern United States on 21 September 2016. No meaningful dependence on destructive modal interference is detected. We conclude that contemporary models of lightning-ionosphere interactions and/or VLF scattering require modification in order to accurately reproduce observations of large early/fast VLF events.

The Influence of Noise in the Neurofeedback Training Sessions in Student Athletes.

Considering that athletes constantly practice and compete in noisy environments, the aim was to investigate if performing neurofeedback training in these conditions would yield better results in performance than in silent ones. A total of forty-five student athletes aged from 18 to 35 years old and divided equally into three groups participated in the experiment (mean ± SD for age: 22.02 ± 3.05 years). The total neurofeedback session time for each subject was 300 min and were performed twice a week. The environment in which the neurofeedback sessions were conducted did not seem to have a significant impact on the training’s success in terms of alpha relative amplitude changes (0.04 ± 0.08 for silent room versus 0.07 ± 0.28 for noisy room, p = 0.740). However, the group exposed to intermittent noise appears to have favourable results in all performance assessments (p = 0.005 for working memory and p = 0.003 for reaction time). The results of the study suggested that performing neurofeedback training in an environment with intermittent noise can be interesting to athletes. Nevertheless, it is imperative to perform a replicated crossover design.

CRYPTOCHROMES promote daily protein homeostasis.

The daily organisation of most mammalian cellular functions is attributed to circadian regulation of clock‐controlled protein expression, driven by daily cycles of CRYPTOCHROME‐dependent transcriptional feedback repression. To test this, we used quantitative mass spectrometry to compare wild‐type and CRY‐deficient fibroblasts under constant conditions. In CRY‐deficient cells, we found that temporal variation in protein, phosphopeptide, and K+ abundance was at least as great as wild‐type controls. Most strikingly, the extent of temporal variation within either genotype was much smaller than overall differences in proteome composition between WT and CRY‐deficient cells. This proteome imbalance in CRY‐deficient cells and tissues was associated with increased susceptibility to proteotoxic stress, which impairs circadian robustness, and may contribute to the wide‐ranging phenotypes of CRY‐deficient mice. Rather than generating large‐scale daily variation in proteome composition, we suggest it is plausible that the various transcriptional and post‐translational functions of CRY proteins ultimately act to maintain protein and osmotic homeostasis against daily perturbation.

Perioperative parenteral fish oil supplementation improves postoperative coagulation function and outcomes in patients undergoing colectomy for ulcerative colitis.

Ulcerative colitis (UC) is an independent risk factor for thromboembolism, especially during the perioperative period. This study aimed to determine the effects of perioperative parenteral nutrition (PN) supplemented with fish oil (FO) on coagulation function and postoperative outcomes in patients with UC. This retrospective cohort included 92 consecutive patients who underwent colectomy for UC. Postoperative coagulation indices and outcomes, including thromboelastography (TEG) findings and comprehensive complication index (CCI), were compared. The relative change in serum D-dimer (ΔD-dimer) levels and maximal amplitude (ΔMA) on TEG were also determined. Patients receiving PN supplemented with FO (n = 48) had lower D-dimer (P = .036) levels on postoperative day (POD) 5 and a higher MA (P < 0.001) on POD 1 than those who did not receive it (n = 44). A lower ΔD-dimer level (P = .048) and ΔMA (P < 0.001) were also observed in patients receiving FO. The incidence of major postoperative complications (6.3 vs 22.7%; P = .017) and CCI (20.9 vs 23.4%; P = .044) were significantly lower in patients receiving FO. In multivariate analysis, FO (odds ratio, 0.231; 95% confidence interval, 0.055-0.971; P = .046) was a positive protector of major postoperative complications. Perioperative PN supplemented with FO improved coagulation function and reduced major postoperative complications in patients with UC requiring colectomy. These results may provide cues in formulating management strategies for preventing thromboembolisms and postoperative complications in patients with UC.

Piezoelectric-sensored sustainable pads for smart railway traffic and track state monitoring: Full-scale laboratory tests

The present paper focuses on an initial assessment into the applicability of sensored sustainable pads, made from recycled polymers and embedded with commonly-accessible piezoelectrics. These sensing devices were used as smart rail pads and inside bituminous sub-ballast to monitor traffic and track state by measuring the stress variations in the components. A series of full-scale laboratory tests were carried out simulating train passage under diverse traffic scenarios and varying track section conditions in a testing box. Results indicated that the smart sustainable pads in both components showed the capacity to detect traffic load variations by measuring relative changes in signal amplitude of the sensor. Nonetheless, the smart rail pads presented higher accuracy to monitor axle loads, while the signals from the sub-ballast were influenced by the position of the sensor and so a higher potential to monitor track performance, rail-sleeper load distribution and detecting phenomena like hanging sleepers.

Different effects of metformin and phenformin on hypoxia-induced Ca2+ fluxes in cultured primary neurons

Recent evidence suggests that metformin and phenformin may exert beneficial effects against neuronal injury in the ischemic brain, however, the difference of action between these two drugs and the molecular mechanism of such protection is not clear. In this study, we investigated whether mild hypoxia-affected neurons exhibit changes in cytosolic calcium handling and whether metformin and phenformin exert any effect on calcium homeostasis in hypoxia-affected neurons. Cultured primary rat cortical cells were stained with calcium sensitive dye Oregon Green 488 BAPTA-1 AM and spontaneous calcium dependent changes of fluorescence were recorded. Using obtained fluorescence traces we estimated changes in relative amplitude of recorded spontaneous signals, changes in frequency of spontaneous activity, and changes in decay of fluorescence traces. We found that hypoxia caused reduction of the relative signal amplitude, increased the spontaneous activity, and slowed the decay of calcium concentration. After pre-treatment of cells with 0.1–0.5 mM metformin, the relative signal amplitude increased and the frequency of spontaneous signals decreased in hypoxia-affected neurons. However, pre-treatment with 1–25 µM phenformin neither increased the relative signal amplitude nor reduced the frequency of spontaneous signals. The decay of fluorescence traces became faster after application of metformin or phenformin comparing to neurons under hypoxic conditions. These results suggest different action of metformin and phenformin in improvement of Ca2+ homeostasis in hypoxia-affected neurons, which may have different effects on neuronal survival and functions after hypoxia/ischemia.

Band-Limited Chirp-Evoked Compound Action Potential in Guinea Pig: Comprehensive Neural Measure for Cochlear Implantation Monitoring.

Patients with severely impaired high-frequency hearing and sufficient residual low-frequency hearing can be provided with a cochlear implant (CI), thereby facilitating ipsilateral electric and acoustic stimulation with established advantages over electric stimulation alone. However, partial or complete hearing loss often occurred after implantation due to, inter alia, acute mechanical trauma to cochlear structures during electrode insertion. Possibilities of intraoperative monitoring using electrocochleography (ECochG) have recently been studied in CI patients, primarily using the ongoing response to low-frequency tone bursts consisting of the cochlear microphonic (CM) and the auditory nerve neurophonic. By contrast, the transient neural response to tone bursts, that is, compound action potential (CAP), was generally less detectable or less sensitive as a monitoring measure, thus falling short of providing useful contribution to electrocochleography analysis. In this study, we investigate using chirps to evoke more robust CAP responses in a limited frequency band by synchronizing neural firing, and thereby improving CAP sensitivity to mechanical trauma in a guinea pig model of cochlear implantation. Stimuli were band-limited between 100 Hz and 10 kHz to investigate their frequency range selectivity as a preliminary model for low-frequency hearing. They were constructed by adding a harmonic series either with zero phase delay (click) or by adjusting the phase delay at a rate that is inversely related to a traveling wave delay model (chirp), with three different parameters to examine level-dependent delay compression. The amplitude spectrum was thus identical between stimuli with differences only in phase. In Experiment 1, we compared input-output functions recorded at the round window in normal-hearing guinea pigs and implemented a high-pass noise masking paradigm to infer neural contribution to the CAP. In Experiment 2, guinea pigs were implanted with a custom-built CI electrode using a motorized micromanipulator. Acute mechanical trauma was simulated during the electrode insertion. At each insertion step, CAP and CM responses were measured at the round window for the following stimuli: broad-band click, band-limited click, and band-limited chirps (3 parameters), and tone bursts at frequencies 1, 2, 4, and 8 kHz. Chirps compared with the equal-band click showed significantly lower thresholds and steeper slopes of sigmoid-fitted input-output functions. The shorter chirp evoked significantly larger amplitudes than click when compared at equal sensation level. However, the click evoked larger amplitudes than chirps at higher levels and correspondingly achieved larger saturation amplitudes. The results of the high-pass noise masking paradigm suggest that chirps could efficiently synchronize neural firing in their targeted frequency band, while the click recruited more basal fibers outside its limited band. Finally, monitoring sensitivity during electrode insertion, defined as relative amplitude change per unit distance, was higher for chirp-evoked CAP and tone burst-evoked CM, but smaller for CAP responses evoked by clicks or tone bursts. The chirp was shown to be an efficient stimulus in synchronizing neural firing for a limited frequency band in the guinea pig model. This study provides a proof of principle for using chirp-evoked CAP as a comprehensive neural measure in CI patients with residual hearing.

EEG based assessment of stress in horses: a pilot study.

As has been hypothesized more than 20 years ago, data derived from Electroencephalography (EEG) measurements can be used to distinguish between behavioral states associated with animal welfare. In our current study we found a high degree of correlation between the modulation index of phase related amplitude changes in the EEG of horses (n = 6 measurements with three different horses, mare and gelding) and their facial expression, measured by the use of the horse grimace scale. Furthermore, the pattern of phase amplitude coupling (PAC) was significantly different between a rest condition and a stress condition in horses. This pilot study paves the way for a possible use of EEG derived PAC as an objective tool for the assessment of animal welfare. Beyond that, the method might be useful to assess welfare aspects in the clinical setting for human patients, as for example in the neonatal intensive care unit.

Feature-Based Evaluation of a Wearable Surface EMG Sensor Against Laboratory Standard EMG During Force-Varying and Fatiguing Contractions

Recent advances in wearable sensors enable recording of electromyography (EMG) outside the laboratory for extended periods of time. However, the properties of wearable EMG systems designed for long-term recording may differ from those of laboratory-standard systems, potentially impacting data. This study evaluated EMG features derived from signals recorded using a wearable system (BioStampRC, MC10 Inc.) against a reference laboratory system (Bagnoli, Delsys Inc.). Surface EMG data from the biceps brachii were recorded simultaneously using both systems during isometric elbow flexion, between 10% and 80% of maximum voluntary contraction (MVC), and during sustained submaximal fatiguing contraction, in twelve subjects. Linear and nonlinear EMG temporal and spectral features were then compared across both systems. No effect of recording system was detected on EMG onset/offset times, or on the relationship between force and EMG root mean squared amplitude. However, the relationships between force and median frequency, percentage determinism and multiscale entropy differed between systems. Baseline noise was also greater for the BioStampRC. Lower median frequencies were observed for the wearable system, likely due to the larger interelectrode distance, however, the relative change in EMG amplitude and median frequency during the fatiguing contraction was similar for both. Percentage determinism increased and multiscale entropy decreased during the fatiguing contraction for both systems, with higher and lower values respectively for the wearable system. Results indicate that the BiostampRC is appropriate for EMG onset/offset and amplitude estimation. However, caution is advised when comparing across systems as spectral and nonlinear features may differ due to electrode design differences.

Quantitative Photoacoustic Method for the Measurement of Absorption Coefficients of Highly Absorbing Samples.

In this study, we present a quantitative photoacoustic (PA) method for performing absorption measurements on highly absorbing samples. Based on the thermoelastic mechanism, the relative changes in PA signal amplitude allowed the determination of absorption coefficients of materials in the 0.19-2500-cm-1 range, with no prior knowledge of the material's optoacoustic properties required. We have tested our new methodology by performing absorption measurements on a series of planar liquid samples as well as gelatinized spherical samples. In this approach, laser-induced ultrasound waves were detected in transmission mode. With the model presented herein and a measurement of the relative change in amplitude of the PA signal at two different known concentrations, the absorption coefficient of the sample can be straightforwardly extracted. Three important advantages are highlighted by this analytical approach. First, no previous knowledge of the optical or acoustic properties of the sample is necessary. Second, only a small quantity of sample is required. Finally, our methodology includes both short- and long-pulse regimes, validating its use for any laser pulse duration so long as the requirement for thermal confinement is fulfilled. Remarkably, this new methodology performs best for thick, highly absorbing samples where traditional spectrophotometry is most challenging and unreliable, offering a promising alternative for quantification of the absorption properties of a range of diverse liquid, and gelatinous-state materials not amenable to conventional methods.

Catalyst State Diagnosis of Three-Way Catalytic Converters Using Different Resonance Parameters—A Microwave Cavity Perturbation Study

Recently, radio frequency (RF) technology was introduced as a tool to determine the oxygen storage level of a three-way catalyst (TWC) for gasoline vehicles. Previous studies on the investigation of commercial catalysts mostly use only the resonant frequency to describe the correlation of oxygen storage level and RF signal. For the first time this study presents a comparison under defined laboratory conditions considering both, resonance frequency and also the quality factor as measurands. Furthermore, various advantages over the sole use of the resonant frequency in the technical application are discussed. Experiments with Ø4.66’’ catalysts and Ø1.66’’ catalyst cores with alternating (rich/lean) gas compositions showed that the relative change in signal amplitude due to a change in oxygen storage is about 100 times higher for the inverse quality factor compared to the resonant frequency. In addition, the quality factor reacts more sensitively to the onset of the oxygen-storage ability, and delivers precise information about the necessary temperature, which is not possible when evaluating the resonant frequency due to the low signal amplitude. As investigations on aged catalysts confirm, the quality factor also provides a new approach to determine operando the ageing state of a TWC.

Using Multiscale Entropy to Assess the Efficacy of Local Cooling on Reactive Hyperemia in People with a Spinal Cord Injury.

Pressure ulcers are one of the most common complications of a spinal cord injury (SCI). Prolonged unrelieved pressure is thought to be the primary causative factor resulting in tissue ischemia and eventually pressure ulcers. Previous studies suggested that local cooling reduces skin ischemia of the compressed soft tissues based on smaller hyperemic responses. However, the effect of local cooling on nonlinear properties of skin blood flow (SBF) during hyperemia is unknown. In this study, 10 wheelchair users with SCI and 10 able-bodied (AB) controls underwent three experimental protocols, each of which included a 10-min period as baseline, a 20-min intervention period, and a 20-min period for recovering SBF. SBF was measured using a laser Doppler flowmetry. During the intervention period, a pressure of 60 mmHg was applied to the sacral skin, while three skin temperature settings were tested, including no temperature change, a decrease by 10 °C, and an increase by 10 °C, respectively. A multiscale entropy (MSE) method was employed to quantify the degree of regularity of blood flow oscillations (BFO) associated with the SBF control mechanisms during baseline and reactive hyperemia. The results showed that under pressure with cooling, skin BFO both in people with SCI and AB controls were more regular at multiple time scales during hyperemia compared to baseline, whereas under pressure with no temperature change and particularly pressure with heating, BFO were more irregular during hyperemia compared to baseline. Moreover, the results of surrogate tests indicated that changes in the degree of regularity of BFO from baseline to hyperemia were only partially attributed to changes in relative amplitudes of endothelial, neurogenic, and myogenic components of BFO. These findings support the use of MSE to assess the efficacy of local cooling on reactive hyperemia and assess the degree of skin ischemia in people with SCI.

Mass Sensing in a Liquid Environment Using Nonlinear Self-Excited Coupled-Microcantilevers

Development of an ultrasensitive mass sensor that can detect the single cell level with high accuracy in the viscous regime has attracted attention because it promotes the development of new drugs and the identification of disease biomarkers. Ultrasensitive mass detection in the viscous regime is investigated on the basis of the relative amplitude change in self-excited coupled microcantilevers. We have previously proposed self-excitation theoretically to directly detect the relative amplitude change, even in high viscosity environments, for which conventional methods based on external or forced excitation are inapplicable. The experimental results confirm quantitative mass sensing on the order of nanograms in water without any influence of spurious resonance peaks. [2018-0053]

Using EMG Amplitude and Frequency to Calculate a Multimuscle Fatigue Score and Evaluate Global Shoulder Fatigue.

The authors developed a function to quantify fatigue in multiple shoulder muscles by generating a single score using relative changes in EMG amplitude and frequency over time. Evaluating both frequency and amplitude components of the electromyographic signal provides a more complete evaluation of muscle fatigue than either variable alone; however, little effort has been made to combine time and frequency domains for the evaluation of myoelectric fatigue. Surface EMG was measured from 14 shoulder muscles while participants performed simulated, repetitive work tasks until exhaustion. Each 60-s work cycle consisted of four tasks (dynamic push, dynamic pull, static drill, static force target matching task) scaled to participants' anthropometrics and strength. The function was generated to calculate a multimuscle fatigue score (MMFS) based on changes in EMG frequency, amplitude, and the number of muscles showing signs of myoelectric fatigue (increase in EMG amplitude; decrease in EMG frequency). The function was evaluated through changes in MMFS over time: first (31.8 ± 14.6), middle (47.6 ± 25.3), last (58.6 ± 35.5) reference exertions ( p < .05). The evaluation of the relationships between MMFS and changes in strength ( r = -0.510) and MMFS and perceived fatigue (RPF) ( r = 0.298) showed significant relationships over time ( p < .05). MMFS scores increased over time ( p < .05) with significant relationships between MMFS and strength changes and RPF ( p < .05). The MMFS allows for comparisons between workplace tasks, which can aid in workplace design to mitigate the development of fatigue.