Changes In Luminance Contrast Research Articles

Effective connectivity in subcortical visual structures in de novo Patients with Parkinson’s Disease

BackgroundParkinson’s disease (PD) manifests with the appearance of non-motor symptoms before motor symptoms onset. Among these, dysfunctioning visual structures have recently been reported to occur at early disease stages. ObjectiveThis study addresses effective connectivity in the visual network of PD patients. MethodsUsing functional MRI and dynamic causal modeling analysis, we evaluated the connectivity between the superior colliculus, the lateral geniculate nucleus and the primary visual area V1 in de novo untreated PD patients (n = 22). A subset of the PD patients (n = 8) was longitudinally assessed two times at two months and at six months after starting dopaminergic treatment. Results were compared to those of age-matched healthy controls (n = 22). ResultsOur results indicate that the superior colliculus drives cerebral activity for luminance contrast processing both in healthy controls and untreated PD patients. The same effective connectivity was observed with neuromodulatory differences in terms of neuronal dynamic interactions. Our main findings were that the modulation induced by luminance contrast changes of the superior colliculus connectivity (self-connectivity and connectivity to the lateral geniculate nucleus) was inhibited in PD patients (effect of contrast: p = 0.79 and p = 0.77 respectively). The introduction of dopaminergic medication in a subset (n = 8) of the PD patients failed to restore the effective connectivity modulation observed in the healthy controls. InterpretationThe deficits in luminance contrast processing in PD was associated with a deficiency in connectivity adjustment from the superior colliculus to the lateral geniculate nucleus and to V1. No differences in cerebral blood flow were observed between controls and PD patients suggesting that the deficiency was at the neuronal level. Administration of a dopaminergic treatment over six months was not able to normalize the observed alterations in inter-regional coupling. These findings highlight the presence of early dysfunctions in primary visual areas, which might be used as early markers of the disease.

Undetectable Changes in Image Resolution of Luminance-Contrast Gradients Affect Depth Perception.

A great number of studies have suggested a variety of ways to get depth information from two dimensional images such as binocular disparity, shape-from-shading, size gradient/foreshortening, aerial perspective, and so on. Are there any other new factors affecting depth perception? A recent psychophysical study has investigated the correlation between image resolution and depth sensation of Cylinder images (A rectangle contains gradual luminance-contrast changes.). It was reported that higher resolution images facilitate depth perception. However, it is still not clear whether or not the finding generalizes to other kinds of visual stimuli, because there are more appropriate visual stimuli for exploration of depth perception of luminance-contrast changes, such as Gabor patch. Here, we further examined the relationship between image resolution and depth perception by conducting a series of psychophysical experiments with not only Cylinders but also Gabor patches having smoother luminance-contrast gradients. As a result, higher resolution images produced stronger depth sensation with both images. This finding suggests that image resolution affects depth perception of simple luminance-contrast differences (Gabor patch) as well as shape-from-shading (Cylinder). In addition, this phenomenon was found even when the resolution difference was undetectable. This indicates the existence of consciously available and unavailable information in our visual system. These findings further support the view that image resolution is a cue for depth perception that was previously ignored. It partially explains the unparalleled viewing experience of novel high resolution displays.

Blue Light Protects Against Temporal Frequency Sensitive Refractive Changes.

Time spent outdoors is protective against myopia. The outdoors allows exposure to short-wavelength (blue light) rich sunlight, while indoor illuminants can be deficient at short-wavelengths. In the current experiment, we investigate the role of blue light, and temporal sensitivity, in the emmetropization response. Five-day-old chicks were exposed to sinusoidal luminance modulation of white light (with blue; N = 82) or yellow light (without blue; N = 83) at 80% contrast, at one of six temporal frequencies: 0, 0.2, 1, 2, 5, 10 Hz daily for 3 days. Mean illumination was 680 lux. Changes in ocular components and corneal curvature were measured. Refraction, eye length, and choroidal changes were dependent on the presence of blue light (P < 0.03, all) and on temporal frequency (P < 0.03, all). In the presence of blue light, refraction did not change across frequencies (mean change -0.24 [diopters] D), while in the absence of blue light, we observed a hyperopic shift (>1 D) at high frequencies, and a myopic shift (>-0.6 D) at low frequencies. With blue light there was little difference in eye growth across frequencies (77 μm), while in the absence of blue light, eyes grew more at low temporal frequencies and less at high temporal frequencies (10 vs. 0.2 Hz: 145 μm; P < 0.003). Overall, neonatal astigmatism was reduced with blue light. Illuminants rich in blue light can protect against myopic eye growth when the eye is exposed to slow changes in luminance contrast as might occur with near work.

The role of luminance and chromatic cues in emmetropisation

At birth most, but not all eyes, are hyperopic. Over the course of the first few years of life the refraction gradually becomes close to zero through a process called emmetropisation. This process is not thought to require accommodation, though a lag of accommodation has been implicated in myopia development, suggesting that the accuracy of accommodation is an important factor. This review will cover research on accommodation and emmetropisation that relates to the ability of the eye to use colour and luminance cues to guide the responses. There are three ways in which changes in luminance and colour contrast could provide cues: (1) The eye could maximize luminance contrast. Monochromatic light experiments have shown that the human eye can accommodate and animal eyes can emmetropise using changes in luminance contrast alone. However, by reducing the effectiveness of luminance cues in monochromatic and white light by introducing astigmatism, or by reducing light intensity, investigators have revealed that the eye also uses colour cues in emmetropisation. (2) The eye could compare relative cone contrast to derive the sign of defocus information from colour cues. Experiments involving simulations of the retinal image with defocus have shown that relative cone contrast can provide colour cues for defocus in accommodation and emmetropisation. In the myopic simulation the contrast of the red component of a sinusoidal grating was higher than that of the green and blue component and this caused relaxation of accommodation and reduced eye growth. In the hyperopic simulation the contrast of the blue component was higher than that of the green and red components and this caused increased accommodation and increased eye growth. (3) The eye could compare the change in luminance and colour contrast as the eye changes focus. An experiment has shown that changes in colour or luminance contrast can provide cues for defocus in emmetropisation. When the eye is exposed to colour flicker the eye grows almost twice as much, and becomes more myopic, compared to when the eye is exposed to luminance flicker. Neural responses of the luminance and colour mechanisms direct accommodation and emmetropisation mechanisms to different focal planes. Therefore, it is likely that the set point of refraction and accommodation is dependent on the sensitivity of the eye to changes in spatial and temporal, colour and luminance contrast.

최대색차신호 표를 이용한 컬러 채도 향상

본 논문에서는 디지털 영상의 색상을 유지하면서 영상의 명암대비 향상과 함께 채도를 향상시키는 방법을 제시한다. 제안방법은 명암대비 향상 후 밝기 변화에 따른 시각적인 채도 변화를 보정하기 위해 최대색차신호 테이블을 이용한다. 최대색차신호 테이블로부터 휘도변화에 따른 가중치를 구하고, 입력 색차신호에 가중치를 곱하여 채도를 밝기에 적응적으로 보정한다. 또한 사용자가 입력한 만큼의 채도를 향상시키는 과정에서 과도한 채도 향상으로 인한 왜곡을 막기 위해 휘도와 색상에 따른 채도의 상관관계를 고려하여 색차신호가 올바른 색역에 사상될 수 있도록 한다. 다양한 특성을 갖는 영상에 대한 실험을 통해 제안방법은 기존방식과 비교하여 효과적으로 컬러 영상의 선명도를 향상시킴을 확인하였다. In this paper, we propose a new color image enhancement method to improve the color saturation as well as luminance contrast in the YCbCr color space. The proposed method uses the maximum color difference table to compensate the perceived saturation changes due to luminance contrast changes. To improve the color saturation, the method first calculates the weighting factor by using the maximum color difference table and then multiplies the weighting factor to the input color difference signals. In this step, it maps color difference signals to proper color region to prevent the color distortion by considering the correlation of color saturations depending on the luminance and hue. The experimental results show that our method effectively improves color saturation compared to the conventional methods.

Howard–Dolman stereovision test at different opponent colour stimuli

The purpose of this study was to investigate visual depth perception of real physical colour stimuli with red-green and blue-yellow opponency. We modified the Howard–Dolman stereotest where subjects should determine the closer of two bars emitting the light of definite colour placed in front of a CRT monitor served as colour background. Two-alternative forced-choice paradigms were used to determine depth perception threshold values. Thresholds close to 5–10 arcsec for luminance and colour contrast stimuli were revealed both for red-green and blue-yellow stimuli. A term, stereosensitivity – a reciprocal magnitude of the stereothreshold – was introduced to separately analyse luminance and colour contrast contributions in total depth perception. Comparing stereo sensitivity values for different colour stimuli, stereo sensitivity in case of red-green is still better than comparing to blue-yellow colour contrast. The colour and luminance contrast in CIE L*a*b* units (at least in the restricted dynamic range) could be applicable as a psychophysical metric to characterise stereo sensitivity. We suppose the colour and luminance contrast guided stereo mechanisms as two additive contributions in total stereo sense. Stereosense thresholds are more sensitive to luminance contrast changes as compared with colour contrast changes (in L*a*b* metric).

The response dynamics of primate visual cortical neurons to simulated optical blur

Neurons in visual cortical area V1 typically respond well to lines or edges of specific orientations. There have been many studies investigating how the responses of these neurons to an oriented edge are affected by changes in luminance contrast. However, in natural images, edges vary not only in contrast but also in the degree of blur, both because of changes in focus and also because shadows are not sharp. The effect of blur on the response dynamics of visual cortical neurons has not been explored. We presented luminance-defined single edges in the receptive fields of parafoveal (1-6 deg eccentric) V1 neurons of two macaque monkeys trained to fixate a spot of light. We varied the width of the blurred region of the edge stimuli up to 0.36 deg of visual angle. Even though the neurons responded robustly to stimuli that only contained high spatial frequencies and 0.36 deg is much larger than the limits of acuity at this eccentricity, changing the degree of blur had minimal effect on the responses of these neurons to the edge. Primates need to measure blur at the fovea to evaluate image quality and control accommodation, but this might only involve a specialist subpopulation of neurons. If visual cortical neurons in general responded differently to sharp and blurred stimuli, then this could provide a cue for form perception, for example, by helping to disambiguate the luminance edges created by real objects from those created by shadows. On the other hand, it might be important to avoid the distraction of changing blur as objects move in and out of the plane of fixation. Our results support the latter hypothesis: the responses of parafoveal V1 neurons are largely unaffected by changes in blur over a wide range.

Contrast Invariance in the Human Lateral Occipital Complex Depends on Attention

The human visual system has a remarkable ability to successfully operate under a variety of challenging viewing conditions. For example, our object-recognition capabilities are largely unaffected by low-contrast (e.g., foggy) environments. The basis for this ability appears to be reflected in the neural responses in higher cortical visual areas that have been characterized as being invariant to changes in luminance contrast: neurons in these areas respond nearly equally to low-contrast as compared to high-contrast stimuli. This response pattern is fundamentally different than that observed in earlier visual areas such as primary visual cortex (V1), which is highly dependent on contrast. How this invariance is achieved in higher visual areas is largely unknown. We hypothesized that directed spatial attention is an important prerequisite of the contrast-invariant responses in higher visual areas and tested this with functional MRI (fMRI) while subjects directed their attention either toward or away from contrast-varying shape stimuli. We found that in the lateral occipital complex (LOC), a visual area important for processing shape information, attention changes the form of the contrast response function (CRF). By directing attention away from the shape stimuli, the CRF in the LOC was similar to that measured in V1. We describe a number of mechanisms that could account for this important function of attention.

Cross-orientation summation in texture segregation

Human texture vision has been modeled as a filter–rectify–filter (FRF) process, in which ‘2nd-order’ filters detect changes in the rectified outputs of luminance-based ‘1st-order’ filters. This study tested the validity of the two basic assumptions of the standard FRF model, namely (a) that the 2nd-order filters are sensitive to spatial modulations in both contrast and orientation, and (b) that the 2nd-order filters are tuned to different 1st-order orientations. In the first experiment, we tested subthreshold summation between two orthogonal carrier orientations in detection of a texture region, which was defined by contrast modulations across regions in the two carrier orientations, while systematically varying the relative change magnitudes between the two orientations. The results showed that the detection thresholds were determined by spatial difference in the contrast integrated over the two orientations. Orientation difference did act as a segregation cue, but only when there was no differences in carrier contrast. This suggests that two mechanisms are involved in texture segregation; one that detects changes in luminance contrast and another that detects changes in orientation. To further analyze the latter mechanism, a second experiment measured cross-orientation summation in the detection of purely orientation-defined textures, using stimuli that were density modulations of two orientations presented among randomly-orientated distractors. Again, the relative modulation magnitudes between the two orientations was systematically varied. The results are consistent with the notions that (a) the dominant orientation is extracted from the 1st-order outputs before the 2nd-order process, and that (b) the 2nd-order, spatial comparison process integrates those dominant signals over different orientations.

Insights into the different exploits of colour in the visual cortex.

A new method that allows controlled masking of luminance contrast has been developed to study the use of chromatic signals in human vision. The method also makes it possible to examine the different uses of chromatic signals (e.g. the generation of perceived colour, or the construction and representation of object structure and form). By using this technique, we studied the threshold detection of chromatic signals in normal trichromats. The results show that chromatic signals are virtually unaffected by ongoing, randomly varying, luminance contrast changes. These findings suggest that chromatic signals are either processed independently or can be separated completely from any confounding luminance contrast components in the stimulus. Thresholds for detection of colour changes only, and for extraction of stimulus structure from chromatic signals in normal trichromats, in subjects with single cone receptor deficiency (i.e. dichromats) and in three subjects with abnormal colour vision caused by bilateral damage to ventromedial, extra-striate visual cortex (i.e. subjects with cerebral achromatopsia) have also been measured. No significant difference in thresholds for the two conditions was observed either in normal trichromats or in dichromats. Subjects with cerebral achromatopsia, however, reveal markedly different thresholds. The results suggest that chromatic signals are processed independently to generate perceived object colour or to construct spatially structured objects, and that these functions involve different neural substrates. The results help to explain, at least in part, why cerebral achromatopsia is a heterogeneous disorder, and why there can be significant differences in the effective use of chromatic signals in subjects described as cerebral achromatopsics.

The projection of the primate superior colliculus upon the dorsal lateral geniculate nucleus: autoradiographic demonstration of interlaminar distribution of tectogeniculate axons

Parkinson’s disease (PD) manifests with the appearance of non-motor symptoms before motor symptoms onset. Among these, dysfunctioning visual structures have recently been reported to occur at early disease stages.This study addresses effective connectivity in the visual network of PD patients.Using functional MRI and dynamic causal modeling analysis, we evaluated the connectivity between the superior colliculus, the lateral geniculate nucleus and the primary visual area V1 in de novo untreated PD patients (n = 22). A subset of the PD patients (n = 8) was longitudinally assessed two times at two months and at six months after starting dopaminergic treatment. Results were compared to those of age-matched healthy controls (n = 22).Our results indicate that the superior colliculus drives cerebral activity for luminance contrast processing both in healthy controls and untreated PD patients. The same effective connectivity was observed with neuromodulatory differences in terms of neuronal dynamic interactions. Our main findings were that the modulation induced by luminance contrast changes of the superior colliculus connectivity (self-connectivity and connectivity to the lateral geniculate nucleus) was inhibited in PD patients (effect of contrast: p = 0.79 and p = 0.77 respectively). The introduction of dopaminergic medication in a subset (n = 8) of the PD patients failed to restore the effective connectivity modulation observed in the healthy controls.The deficits in luminance contrast processing in PD was associated with a deficiency in connectivity adjustment from the superior colliculus to the lateral geniculate nucleus and to V1. No differences in cerebral blood flow were observed between controls and PD patients suggesting that the deficiency was at the neuronal level. Administration of a dopaminergic treatment over six months was not able to normalize the observed alterations in inter-regional coupling. These findings highlight the presence of early dysfunctions in primary visual areas, which might be used as early markers of the disease.