Septoria tritici blotch (STB) caused by the ascomycete Zymoseptoria tritici (Z. tritici) is currently the most prevalent foliar disease in wheat in the Nordic-Baltic region. Fungicide availability in this region differs greatly and is generally more limited than in other European regions. Monitoring of fungicide sensitivity is an essential tool to survey changes in fungal populations in order to react and be able to adapt recommendations for fungicide use. In this study the authors give an overview of the current situation of 14α-demethylation inhibitor (DMI) and quinone outside inhibitor (QoI) sensitivity of Z. tritici from Scandinavia and the Baltic countries. A total of 985 isolates from the Nordic-Baltic region were investigated for EC50 of DMI epoxiconazole and prothioconazole. Fungicide sensitivity remains at a high level with values ranging from 0.07 to 0.48 mg L−1 for epoxiconazole and 1.17 to 9.47 mg L−1 for prothioconazole. Point mutation I381V in the DMI target gene CYP51 was dominant throughout the region, but mutations D134G, V136A/C and S524T were also detected in the population in 2014. Screening for inserts in the CYP51 promoter region revealed that a ~ 1000 bp insert is predominant in the entire region. Only a single isolate was found in Denmark, harbouring the 120 bp insert, known to reduce fungicide sensitivity. Two Danish isolates which had elevated resistance levels were associated with an enhanced efflux. Significant differences were found across the area for the presence of G143A, conferring QoI resistance. As there is only limited access to results from this area, these findings can serve as reference for future fungicide sensitivity investigations and for evaluation of changes in the Northern European Z. tritici population.