Changes In Disk Structure Research Articles

The Dynamic, Chimeric Inner Disk of PDS 70

Transition disks, with inner regions depleted in dust and gas, could represent later stages of protoplanetary disk evolution when newly formed planets are emerging. The PDS 70 system has attracted particular interest because of the presence of two giant planets in orbits at tens of astronomical units within the inner disk cavity, at least one of which is itself accreting. However, the region around PDS 70 most relevant to understanding the planet populations revealed by exoplanet surveys of middle-aged stars is the inner disk, which is the dominant source of the system’s excess infrared emission but only marginally resolved by the Atacama Large Millimeter/submillimeter Array. Here we present and analyze time-series optical and infrared photometry and spectroscopy that reveal the inner disk to be dynamic on timescales of days to years, with occultation by submicron dust dimming the star at optical wavelengths, and 3–5 μm emission varying due to changes in disk structure. Remarkably, the infrared emission from the innermost region (nearly) disappears for ∼1 yr. We model the spectral energy distribution of the system and its time variation with a flattened warm (T ≲ 600 K) disk and a hotter (1200 K) dust that could represent an inner rim or wall. The high dust-to-gas ratio of the inner disk, relative to material accreting from the outer disk, means that the former could be a chimera consisting of depleted disk gas that is subsequently enriched with dust and volatiles produced by collisions and evaporation of planetesimals in the inner zone.

Growth differentiation factor-6 attenuates inflammatory and pain-related factors and degenerated disc-induced pain behaviors in rat model.

Previous studies have indicated that growth differentiation factor 6 (GDF6) is a potential candidate for intervertebral disc (IVD) degeneration (IDD) treatment. Here, we investigated the effect of GDF6 on IDD by examining changes in disc structure and the expression of inflammatory and pain-related factors. A rat posterior disc puncture model of single segments and three consecutive segments was constructed, and GDF6 or phosphate-buffered solution was administered via intradiscal injection 1 or 2 weeks after surgery. Magnetic resonance imaging showed a clear degeneration signal in the punctured disc, which was inhibited by GDF6. Histological staining revealed that GDF6 did not significantly improve the structure of IVDs in rats 8 weeks after puncture surgery, but it had an inhibitory effect on expression of the tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-1β in the IVD. Furthermore, GDF6 was found to protect the morphology and structure of the IVD 32 weeks after surgery. Mechanical and thermal hyperalgesia tests suggested that GDF6 injection can significantly improve mechanical and thermal-stimulated pain behavior in rats and inhibit the expression of inflammatory factors TNF-α and IL-1β and the pain factor calcitonin gene-related peptide in the dorsal root ganglion. A rat protein array test indicated that GDF6 could reduce the expression of cytokines IL-6, intercellular cell adhesion molecule-1, matrix metalloproteinase-13, IL-1β, and TNF-α and increase the expression of tissue inhibitor of metalloproteinases 1, Transforming growth factor-beta 2, IL-10, and resistin in a TNF-α-induced IDD cell model. Thus, our study demonstrates that GDF6 can improve the structure of the IVD, inhibit the expression of inflammatory and pain-related factors, and improve pain behavior in rats. Clinical Significance: To establish further preclinical research and clinical trials, comprehensive data are needed to validate the regenerative properties of GDF6. Ideally, a regenerative agent should also be able to relieve discogenic pain, achieving the best clinical outcomes.

Time-resolved photometry of the young dipper RX J1604.3-2130A

Context. RX J1604.3-2130A is a young, dipper-type, variable star in the Upper Scorpius association, suspected to have an inclined inner disk, with respect to its face-on outer disk. Aims. We aim to study the eclipses to constrain the inner disk properties. Methods. We used time-resolved photometry from the Rapid Eye Mount telescope and Kepler 2 data to study the multi-wavelength variability, and archival optical and infrared data to track accretion, rotation, and changes in disk structure. Results. The observations reveal details of the structure and matter transport through the inner disk. The eclipses show 5 d quasi-periodicity, with the phase drifting in time and some periods showing increased/decreased eclipse depth and frequency. Dips are consistent with extinction by slightly processed dust grains in an inclined, irregularly-shaped inner disk locked to the star through two relatively stable accretion structures. The grains are located near the dust sublimation radius (~0.06 au) at the corotation radius, and can explain the shadows observed in the outer disk. The total mass (gas and dust) required to produce the eclipses and shadows is a few % of a Ceres mass. Such an amount of mass is accreted/replenished by accretion in days to weeks, which explains the variability from period to period. Spitzer and WISE infrared variability reveal variations in the dust content in the innermost disk on a timescale of a few years, which is consistent with small imbalances (compared to the stellar accretion rate) in the matter transport from the outer to the inner disk. A decrease in the accretion rate is observed at the times of less eclipsing variability and low mid-IR fluxes, confirming this picture. The v sin i = 16 km s−1 confirms that the star cannot be aligned with the outer disk, but is likely close to equator-on and to be aligned with the inner disk. This anomalous orientation is a challenge for standard theories of protoplanetary disk formation.

The role of disc self-gravity in circumbinary planet systems – I. Disc structure and evolution

We present the results of 2-dimensional hydrodynamic simulations of self-gravitating circumbinary discs around binaries whose parameters match those of the circumbinary planet-hosting systems Kepler-16, -34 and -35. Previous work has shown that non-self-gravitating discs in these systems form an eccentric precessing inner cavity due to tidal truncation by the binary, and planets which form at large radii migrate until stalling at this cavity. While this scenario appears to provide a natural explanation for the observed orbital locations of the circumbinary planets, previous simulations have failed to match the observed planet orbital parameters. The aim of this work is to examine the role of self-gravity in modifying circumbinary disc structure as a function of disc mass, prior to considering the evolution of embedded circumbinary planets. In agreement with previous work, we find that for disc masses between 1--5 times the minimum mass solar nebula (MMSN), disc self-gravity affects modest changes in the structure and evolution of circumbinary discs. Increasing the disc mass to 10 or 20 MMSN leads to two dramatic changes in disc structure. First, the scale of the inner cavity shrinks substantially, bringing its outer edge closer to the binary. Second, in addition to the eccentric inner cavity, additional precessing eccentric ring-like features develop in the outer regions of the discs. If planet formation starts early in the disc lifetime, these changes will have a significant impact on the formation and evolution of planets and precursor material.

Evaluation of canine intervertebral disc degeneration in colour-coded computed tomography.

BackgroundCanine intervertebral disc degeneration can lead to intervertebral disc disease. Mild degenerative changes in the structure of the canine intervertebral disc can be identified in magnetic resonance images, whereas these changes are not visible in computed tomographic images. Therefore, one aim of this study was to detect whether colour-coded computed tomography enhances the visibility of mild degenerative changes in the canine disc structure compared to non-contrast computed tomography. Furthermore, the study aimed to detect if intervertebral disc degeneration could be classified with a higher reliability in colour-coded images than in non-contrast images.ResultsComputed tomographic image studies of 144 canine intervertebral discs were coloured using three different lookup tables. Canine intervertebral disc degeneration was evaluated by three observers using a 5-grade classification system and compared to the evaluation of non-contrast CT and MRI images. A moderate to almost perfect intraobserver and a moderate to substantial interobserver agreement were found depending on the used colour code. On comparing non-contrast and colour-coded CT significant differences were found by one observer only. Significant differences in evaluation were found in grading intervertebral disc degeneration in MRI and colour-coded CT.ConclusionsIntervertebral disc degeneration could not be classified with a higher reliability on colour-coded images compared to non-contrast images. Furthermore, colour-coded CT did not enhance the visibility of mild degenerative changes in disc structure compared to non-contrast CT.However, the better intraobserver agreement and the subjective impression of the observers highlighted that the usage of colour encoded CT data sets with a wide range of tonal values of few primary and secondary colours may facilitate evaluation.

CONNECTING X-RAY AND INFRARED VARIABILITY AMONG YOUNG STELLAR OBJECTS: RULING OUT POTENTIAL SOURCES OF DISK FLUCTUATIONS

Variability in the infrared emission from disks around pre-main sequence stars over the course of days to weeks appears to be common, but the physical cause of the changes in disk structure are not constrained. Here we present coordinated monitoring of one young cluster with the Spitzer and Chandra space telescopes aimed at studying the physical source of the variability. In fall 2011 we obtained ten epochs of Chandra ACIS photometry over a period of 30 days with a roughly 3 day cadence contemporaneous with 20 epochs of Spitzer [3.6],[4.5] photometry over 40 days with a roughly 2 day cadence of the IC 348 cluster. This cadence allows us to search for week to month long responses of the infrared emission to changes in the high-energy flux. We find no strong evidence for a direct link between the X-ray and infrared variability on these timescales among 39 cluster members with circumstellar disks. There is no significant correlation between the shape of the infrared and X-ray light curves, or between the size of the X-ray and infrared variability. Among the stars with an X-ray flare none showed evidence of a correlated change in the infrared photometry on timescales of days to weeks following the flare. This lack of connection implies that X-ray heating of the planet forming region of the disk is not significant, although we cannot rule out rapid or instantaneous changes in infrared emission.

An analysis of cervical non-infectious inflammatory myelitis risk factors

Background: Non-infectious inflammatory myelitis or non-infectious myelitis (NIM) is an inflammatory condition that occurs following an immune response in the central nervous system (CNS). In cases of spinal disc degeneration, multiple factors converge to cause pathologic changes in disc structure. To date, no studies have examined the potential relationship between disc degeneration and NIM.Objectives: To investigate the relationship between cervical NIM and cervical disc degeneration.Methods: Magnetic resonance imaging (MRI) was used to examine 85 patients with cervical NIM. Peripheral levels of the pro-inflammatory cytokines, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) were also measured. Non-infectious myelitis occurrence rates and TNF-alpha and IL-6 levels were compared between patients with cervical disc degeneration and a control group. The relationship between cervical NIM and cervical disc degeneration was analyzed with logistic regression and a receiver operating characteristic (ROC) curve.Results: Magnetic resonance imaging showed that 78·8% of patients with myelitis exhibited disc degeneration compared to only 18·9% of the control group. Moreover, IL-6 and TNF-alpha levels in patients with NIM were significantly higher than those in the control group; levels of these inflammatory cytokines were even higher in NIM patients with cervical disc degeneration than in those without.Conclusions: Our results suggest that patients with cervical NIM have a higher incidence of cervical disc degeneration, indicating that cervical disc degeneration is likely a possible risk factor in cervical NIM progression. Future quantitative studies are required to confirm this observation.

Osteogenic Protein-1 Injection Into a Degenerated Disc Induces the Restoration of Disc Height and Structural Changes in the Rabbit Anular Puncture Model

In vivo study of the effect of injection of osteogenic protein-1 (OP-1) on a rabbit anular needle puncture model of intervertebral disc (IVD) degeneration. To study radiographic, magnetic resonance imaging (MRI), biochemical, and histologic changes in the rabbit IVD after injection of OP-1 into the nucleus pulposus in a needle puncture disc degeneration model. Growth factors, such as OP-1, have the ability to stimulate synthesis of proteoglycans and collagen in vitro. The in vivo injection of OP-1 into the normal rabbit IVD has increased disc height and proteoglycan content in the anulus fibrosus and nucleus pulposus. However, to our knowledge, no attempts have yet been made to determine the effects of these growth factors in an in vivo model of disc degeneration. New Zealand adolescent white rabbits (n = 90, 8 for baseline evaluation, 82 at 8 times) received an anular puncture in 2 noncontiguous discs with an 18-gauge needle to induce disc degeneration. Four weeks later, either 5% lactose (10 microL) or OP-1 (100 microg in 10 microL 5% lactose) was injected into the center of the nucleus pulposus. The disc height was followed radiographically for up to 24 weeks after the injections. At the 2, 4, 8, 12, and 24-week times after the injection, rabbits were euthanized, and MRI of the harvested spinal columns was obtained to grade the degeneration. The discs injected with OP-1 or lactose and noninjected discs were subjected to biochemical and histologic analysis. The specimens at the 24-week time were limited to histologic evaluation. The anular puncture with a needle induced a consistent disc narrowing within 4 weeks. The injection of OP-1 induced a restoration of disc height at 6 weeks, which was sustained for the entire experimental period, up to 24 weeks after the injection. The injection of lactose alone did not change the course of disc narrowing over the same time. MRI grading score showed significant differences between the OP-1 and lactose groups at the 8, 12, and 24-week times, suggesting an increase in water content in the nucleus pulposus of the OP-1 group. The proteoglycan content of the nucleus pulposus and anulus fibrosus was significantly higher in the OP-1 group than in the control group. The degeneration grades of the punctured discs in the OP-1 group were significantly lower than those in the lactose group. The results of this study show the feasibility of restoring degenerative rabbit discs by a single injection of OP-1 into the nucleus pulposus. Importantly, the effects of the OP-1 injection on disc height were sustained for up to 24 weeks. The metabolic changes in the cells, following a single injection, might be sustained and, thus, induce long-term changes in disc structure. An efficacy study in large animals is required to show further that the intradiscal injection of OP-1, or bone morphogenetic proteins or growth factors with similar properties would be useful for the structural restoration of the IVD in humans.

Imaging protoplanetary disks with a square kilometer array

The recent detections of extrasolar giant planets has revealed a surprising diversity of planetary system architectures, with many very unlike our Solar System. Understanding the origin of this diversity requires multi-wavelength studies of the structure and evolution of the protoplanetary disks that surround young stars. Radio astronomy and the square kilometer array (SKA) will play a unique role in these studies by imaging thermal dust emission in a representative sample of protoplanetary disks at unprecedented sub-AU scales in the innermost regions, including the “habitable zone” that lies within a few AU of the central stars. Radio observations will probe the evolution of dust grains up to centimeter-sized “pebbles”, the critical first step in assembling giant planet cores and terrestrial planets, through the wavelength dependence of dust emissivity, which provides a diagnostic of particle size. High resolution images of dust emission will show directly mass concentrations and features in disk surface density related to planet building, in particular the radial gaps opened by tidal interactions between planets and disks, and spiral waves driven by embedded protoplanets. Moreover, because orbital timescales are short in the inner disk, synoptic studies over months and years will show proper motions and allow for the tracking of secular changes in disk structure. SKA imaging of protoplanetary disks will reach into the realm of rocky planets for the first time, and they will help clarify the effects of the formation of giant planets on their terrestrial counterparts.

Corrosion of Electronic and Magnetic Devices and Materials

ABSTRACTCorrosion of thin film structures commonly used in electronic and magnetic devices is discussed. Typical failure modes are presented, and galvanic corrosion is discussed in some detail since it is one common problem with such devices. A graphical explanation for the determination of the ohmic potential drop during galvanic corrosion is presented. The corrosion problem of thin film disks is shown to have changed during the past ten years owing to changes in disk structure. The corrosion susceptibility of two antiferromagnetic alloys used for exchange coupling to soft magnetic layers is discussed.

Coronagraphic imaging of the Beta Pictoris circumstellar disk - Evidence of changing disk structure within 100 AU

view Abstract Citations (64) References (17) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Coronagraphic Imaging of the beta Pictoris Circumstellar Disk: Evidence of Changing Disk Structure within 100 AU Golimowski, David A. ; Durrance, Samuel T. ; Clampin, Mark Abstract New R-band images of the Beta Pictoris circumstellar disk obtained with the Adaptive Optics Coronagraph expose the disk inward to 40 AU from the star. From these images, the first reliable optical photometry of the disk within 100 AU of Beta Pic is reported. Across a radius of 100 AU, the radial power-law dependence of the disk-midplane surface brightness undergoes an abrupt transition, with power-law indices changing within 100 AU from -3.5 to -2.4 in the NE extension and from -4.2 to -1.9 in the SW extension. This result confirms the previously noted asymmetry in the brightness gradient beyond 250 AU, and suggests an inverted asymmetry within 100 AU. The geometrical thickness of the disk appears nearly constant within about 115 AU and increases proportionally with radius beyond about 115 AU. These changes in brightness gradient and disk thickness are consistent with the two-component disk models of Backman et al. (1992). The observed changes in disk structure at about 100 AU may mark the boundary of rapid ice sublimation within which only refractory grains exist, but may also reflect a flattened grain distribution associated with planetary formation within 40 AU. Publication: The Astrophysical Journal Pub Date: July 1993 DOI: 10.1086/186907 Bibcode: 1993ApJ...411L..41G Keywords: Coronagraphs; Stellar Envelopes; Charge Coupled Devices; Stellar Luminosity; Stellar Orbits; Stellar Spectrophotometry; Astrophysics; STARS: CIRCUMSTELLAR MATTER; STARS: INDIVIDUAL CONSTELLATION NAME: BETA PICTORIS full text sources ADS | data products SIMBAD (1)

Circumstellar material associated with solar-type pre-main-sequence stars - A possible constraint on the timescale for planet building

The observed frequency distribution of near-IR excesses for a sample of 83 stars in the Taurus-Auriga star-forming complex is used to provide an estimate of the number of solar-type premain-sequence (PMS) stars surrounded by circumstellar disks. The results suggest that if all such PMS stars are initially surrounded by disks, then disk lifetimes must range from much less than 3 x 10 to the 6th yr to about 10 to the 7th yr, providing a constraint on the time available for planet building. PMS stars with small near-IR excesses, but significant mid-IR and far-IR excesses, provide some evidence for changes in disk structure with time.

The lumbar intervertebral disk. A clinicopathological correlation based on over 100 laminectomies.

The exact etiology and pathogenesis of intervertebral disk herniation remains unknown. However, man's erect posture and the process of aging are known to produce certain changes in disk structure. The semiliquid gel (nucleus pulposus) loses much of its highly elastic nature and becomes more fibrotic. Degeneration occurs by an increased deposition of collagen fibrils and there is a loss of nucleus water content and mucoid substance.¹The nucleus, as a three-dimensional lattice gel structure of a protein-polysaccharide complex, is prone to degeneration with aging.² Microscopic evaluation of disks removed at surgery has not been able to correlate clinical symptoms and signs since they show only variable amounts of fibrocartilaginous tissue.³It has been my personal observation in experiences with over 100 laminectomies in the lum bar region that simple gross examination of the lesional tissue offers a better correlation with the clinical findings. <h3>Method</h3> The usual clinical