Changes In Blood Flow Perfusion Research Articles

CEUS examination of the outcome of radiofrequency ablation of canine prostate lesions

Purpose To determine the feasibility of using contrast-enhanced ultrasonography (CEUS) to dynamically examine the scope and development of radiofrequency ablation (RFA) lesions in the canine prostate. Material and methods Ten male canines were divided into two groups of five canines each: the 1 week after the RFA group and the 1 month after the RFA group. RFA was performed on one side of the prostate in each canine. For the 1 month after the RFA group, the other side of the prostate underwent RFA prior to euthanasia, and the RFA lesion on this side was included as the immediate RFA group. The RFA lesion volume was measured by CEUS. The evaluation efficacy of CEUS for prostate RFA lesions was determined and compared with the pathological measurements. Results In the immediately after RFA group, 1 week after RFA group, and 1 month after RFA group, the RFA lesion volumes were 0.77 ± 0.34, 1.11 ± 0.61, and 0.19 ± 0.09 cm3, as measured by CEUS; the volumes measured by pathology at the corresponding time points were 0.85 ± 0.28, 0.96 ± 0.31, and 0.20 ± 0.06 cm3, respectively. CEUS accurately assessed the RFA lesions at all the time points, and the measurement results were not significantly different from those of the pathological results (p > .05). Conclusions CEUS reflects the extent of prostate RFA lesions and dynamically shows their changes in blood flow perfusion.

Low Cost Laser Speckle Imaging System for Blood Flow Assessment

This paper aims to demonstrate the feasibility of using a low cost laser speckle imaging built for the detection of changes of tissue blood flow with different experimental conditions. Images of anterior portion of the wrist of four healthy adult volunteers illuminated by a laser source of wavelength 650 nm were collected via a monochromatic charge-coupled device (CCD) imager. The mean and standard deviation (SD) of blood flow perfusion was predicted as 3.92 ± 1.47 and 2.90 ± 1.39, respectively, for measurements at rest condition and during blood flow occlusion. This work showed the ability of the developed system to detect changes in blood flow perfusion with differences in the experimental conditions. However, further works are required to further confirm the suitability of the system before it is used for different clinical applications such as monitoring of blood flow during diabetic foot ulcers healing following standard medical treatment.