Negative Mood Changes Research Articles

The Initial Experience of Eslicarbazepine in Children at Three Canadian Tertiary Pediatric Care Centers.

Eslicarbazepine (ESL) is a once-daily, third-generation antiseizure medication for focal-onset seizures. The primary mechanism of action is enhancing the slow inactivation of voltage-gated sodium channels. The study objective was to review real-world experience regarding retention rate, efficacy, and tolerability of eslicarbazepine, soon after it became available for children in Canada. A retrospective review was performed on all patients prescribed eslicarbazepine from September 2017 to June 2020, with at least 3 years of follow-up data, at 3 Canadian tertiary care pediatric centers. Fifty patients were identified, and the mean age of eslicarbazepine initiation was 12.4 years (range 3-19 years). Most patients had drug-resistant epilepsy, trying a mean of 5.04 (range 0-14) antiseizure medications before the initiation of eslicarbazepine. Twenty-four patients (48.0%) experienced adverse effects, including dizziness (n = 10), drowsiness (n = 6), dizziness and drowsiness (n = 1), nausea and abdominal pain (n = 4), transient unsteadiness and diplopia (n = 1), and negative mood changes (n = 2). None had serious adverse effects, including rash. The retention rate of eslicarbazepine at last follow-up was 70%. Fifteen (30%) had ≥50% seizure reduction, with 2 of these patients becoming seizure free. Ten (20%) had 25% to 50% reduction, 2 (4%) had worsening of seizures, and 17 (34%) had no change in seizure frequency. The study results support the long-term effectiveness and tolerability of eslicarbazepine in a cohort of children with predominantly drug-resistant epilepsy in a real-life setting from 3 Canadian centers with initial use after approval. Adverse effects were nonserious, infrequently leading to eslicarbazepine discontinuation.

Contraception Choice for Female Endurance Athletes: What's Sport Got to Do With It? A Cross-Sectional Survey.

While there are several prescribed contraceptive methods available, limited evidence exists to guide contraceptive decision-making in the context of endurance sport. Study objectives were to characterize current and previous use, perceived impacts, and the decision process around contraceptives in endurance athletes. This was an online survey study with female endurance athletes recruited through social media and emails to university/club coaches and sport organizations. Quantitative and qualitative data were analyzed with descriptive statistics and conventional content analysis, respectively. A total of 323 female endurance athletes participated. Among current contraception users (n = 182), 51% used hormonal intrauterine devices (hIUDs), 29% oral contraceptive pills (OCPs), and 13% nonhormonal IUDs (nhIUDs). hIUD users had the highest perceived positive training (39%) and competition (29%) impacts, citing reduced menstrual bleeding and symptoms as positive side effects. OCP and nhIUD users had higher rates of perceived negative training impacts (OCPs 10%, nhIUDs 30%). For OCP users, 31% reported perceived adverse body composition outcomes and 37% reported negative mood changes. Among nhIUD users, 74% experienced heavier, more irregular menstrual bleeding. Over half of participants were unsure about the impact of their current method on performance. For contraceptive selection, 95% felt that information from physicians was important, yet 32% felt performance was inadequately considered during counseling discussion. Athletes reported less frustration with their contraception choice when counseled in the context of sport. This exploratory study quantifies and qualifies the lived experiences of female endurance athletes with contraception. hIUDs were the most currently used and well-tolerated contraceptives among participants. This research offers valuable insights for athletes seeking contraception and looking to optimize both performance and health, along with the healthcare professionals guiding them.

(085) DAILY CHANGES IN GENITAL PAIN, NON-GENITAL PAIN, AND MOOD, AS PREDICTORS OF SEXUAL DESIRE AND SEX WITH PARTNER: THE ROLE OF POSITIVE MOOD AND THE NEED FOR A POSITIVE PSYCHOLOGY OF SEX

Abstract Introduction There is a lack of research using prospective daily reports to study the associations between genital pain, psychological state, and sexual function. Although many studies have examined the relations among these variables, the most common strategy used is one-time retrospective accounts, which are limited by recall bias and the inability to study day-to-day variations in these symptoms. Objective To examine how day-to-day changes in genital pain influence daily changes in negative mood, and how day-to-day changes in genital pain and psychological symptoms are associated with daily changes in sexual desire and having sex with a partner. Methods A sample of 258 women with genital pain completed daily surveys measuring pain symptoms, psychological state, and sexual desire and activity (n=5831 surveys total; M=20.6 surveys per participant). Daily reports of genital pain addressed pain intensity, duration, and type (continuous vs intermittent); daily reports of psychological state addressed feeling depressed, tense/on edge, happy, and attractive/beautiful; and daily reports of non-genital pain addressed headaches and cramps. Presence of menstruation was also queried. Multilevel analyses tested for effects of genital pain on negative mood; and for effects of all pain and psychological symptoms on sexual desire and sex with partner. Results Analyses presented in tables 1 and 2 consider only days when genital pain was present (3316 surveys; 57% of surveys). Analyses including days with no genital pain were also conducted, recoding pain intensity and duration as zero, and excluding pain type, with only minor changes in results which did not change the overall conclusions. Table 1 presents results from models testing for effects of genital pain on feeling depressed and feeling tense/on edge, and show that, controlling for random intercepts of individual participants, feeling depressed was significantly predicted by all three pain scores, whereas feeling tense/on edge was predicted only by pain intensity and duration. Table 2 presents results from models predicting sexual desire/libido and having sex with partner from all predictor variables while controlling for random intercepts of individual participants. Overall, the results from these models show that the strongest and most consistent predictors across the two outcomes were the psychological variables of feeling tense/on edge, feeling happy and feeling attractive. Feeling depressed had no effect on either outcome. Of the genital pain symptoms, only pain duration had an effect on desire, whereas both pain duration and intensity predicted sex with partner. Pain intensity showed a positive association with sex with partner, which likely reflects an increase in pain intensity after having sex. Conclusions The current findings illustrate the potential impact of genital pain on negative emotions, as well as the importance of positive mood (feeling happy and attractive) on sexual desire and activity. Whereas past research has often focused on negative affect as an outcome of genital pain1, and as a predictor of sexual function2, the present study suggests that we give more attention to positive mood and a positive psychology approach3 in addressing the link between genital pain and sexual function. Such an approach may also have broader implications for general wellness. Disclosure Yes, this is sponsored by industry/sponsor: Data was partially collected using the app “Vulvae”, which is a free-to-use app, and presents no conflict of interest for either of the authors. Clarification: No industry support in study design or execution.

Relationship of increased fruit/vegetable intake with reduced consumption of sweets: Psychological mechanisms and associated weight loss in women within behavioral obesity treatments

Although an increase in fruit and vegetable (FV) consumption in adults might result in reductions in their intake of sweets, there has been minimal direct testing of this. Women participated in 6-month community-based obesity treatment conditions where either their psychological skills development (n = 66) or knowledge regarding healthful eating and exercise (n = 39) was emphasized. Improvements in FV and sweets intake, eating-related self-regulation, self-efficacy for controlled eating, and negative mood were significantly more pronounced in the psychological skills group participants. Together, participants’ change in self-regulation, self-efficacy, and mood significantly mediated the relationship of their changes in FV and sweets. Within simple mediation analyses, participants’ changes in self-efficacy and negative mood were significant mediators, and their treatment group membership moderated effects on sweets. We provided suggestions for future treatments based on the present findings.

Temporal Aspects of Psychosocial Mediators of the Exercise-Weight Loss Maintenance Relationship Within Scalable Behavior-Change Treatments.

Limited knowledge of psychological correlates of weight loss is associated with continuing failures of behavioral obesity treatments beyond the short term. This study aimed to inform health professionals' obesity interventions via an increased knowledge of mediators of the exercise-weight loss maintenance relationship. Women participated in 6-month obesity treatments within community settings emphasizing moderate exercise and self-regulation skills development via primarily in-person (n = 54) or primarily written (n = 54) means. Changes in mood, self-regulating eating, and weight over 6, 12, and 24 months were assessed. A moderated mediation model was tested using the PROCESS macro instruction. Improvements in mood, self-regulating eating, and weight were significantly greater in the in-person group. The relationship between a dichotomous measure of completing at least 3 sessions of exercise per week (or not) and change in weight over 6 months was no longer significant when the mediators of changes in negative mood and self-regulation of eating were sequentially entered. Paths of exercise→negative mood reduction→eating self-regulation increase→weight loss over 6, 12 and 24 months were significant. Exercise self-regulation at Month 3 significantly moderated the mood change→eating self-regulation change relationship. Based on the identified paths, scalable obesity-treatment content and emphases were informed. This could help guide health professionals' actions concerning the management of obesity.

Side effects of monaural beat stimulation during sustained mental work on mind wandering and performance measures.

Excessive mind wandering (MW) contributes to the development and maintenance of psychiatric disorders. Previous studies have suggested that auditory beat stimulation may represent a method enabling a reduction of MW. However, little is known about how different auditory stimulation conditions are subjectively perceived and whether this perception is in turn related to changes in subjective states, behavioral measures of attention and MW. In the present study, we therefore investigated MW under auditory beat stimulation and control conditions using experience sampling during a sustained attention to response task (SART). The subjective perception of the stimulation conditions, as well as changes in anxiety, stress and negative mood after versus before stimulation were assessed via visual-analog scales. Results showed that any auditory stimulation applied during the SART was perceived as more distracting, disturbing, uncomfortable and tiring than silence and was related to more pronounced increases of stress and negative mood. Importantly, the perception of the auditory conditions as disturbing was directly correlated with MW propensity. Additionally, distracting, disturbing and uncomfortable perceptions predicted negative mood. In turn, negative mood was inversely correlated with response accuracy for target stimuli, a behavioral indicator of MW. In summary, our data show that MW and attentional performance are affected by the adverse perception of auditory stimulation, and that this influence may be mediated by changes in mood.

Post-Traumatic Stress Disorder Symptoms among Pediatric Healthcare Workers.

Post-traumatic stress disorder symptoms related to work in pediatric departments aremajor public health problems, as they directly affect health organizations, healthcare workers, and, due to the poor quality of care, the patients as well. The post-traumatic symptoms that a healthcare worker may experience are related to intrusion, avoidance, negative changes in cognition and mood, and changes in arousal and reactivity. The aim of the present investigation was to identify risk factors that contribute to the development of PTSD in pediatric healthcare workers, in order to implement necessary workplace measures. A sample of four hundred and forty-five pediatric workers at seven Greek public hospitals consented to participate in the survey. Socio-demographic data and a post-traumatic checklist (5th edition) were used to diagnose post-traumatic stress disorder. According to the results, risk factors for the development of post-traumatic symptoms include medical or nursing errors, threats to a child's life, and incidents of workplace bullying. More specifically, 25.2% of the participants had a provisional PTSD diagnosis, 72.8%of the sample experienced an incident involving a medical or nursing error in their workplace related to the treatment or care of a child, 56% experienced an incident involving a child's death or a threat to a child's life due to a serious illness or injury, and 55.5% experienced an incident of workplace bullying. In addition, it was found that having a university-level education, master's, or PhD, working in a circular shift, being assigned to a department by management rather than the worker, and dissatisfaction with salary were associated with post-traumatic stress disorder. The high rates of PTSD symptoms among participants highlight the need for prevention and management measures to protect and support the mental health of workers in pediatric departments. We propose frequent evaluations of the mental health of employees, more time for rest, incentives for professional development, utilization of their specializations and specialties, support from mental health specialists when symptoms are diagnosed, and the option for employees to change departments if they wish or if they show symptoms of mental trauma.

Effect of Facial Emotional Feedback Through Facial Electrical Stimulation on Mood Change and Its Clinical Application in Participants with Mild Depression: A Multiple Baseline Case Study

Background: The facial feedback hypothesis proposes that facial expressions influence people's emotional experiences. Objectives: The current study, conducted in 2022, aimed to investigate the impact of facial feedback on the nature and magnitude of changes in emotion, mood, and cognitive-emotional factors among individuals with mild depression. This was achieved through the use of electrical stimulation of the facial muscles. This study aimed to investigate the impact of bilateral electrical stimulation on the frontalis muscles (which act as inhibitory muscles of the corrugator) and zygomaticus muscles on the emotions and moods of individuals with mild depression. Methods: In a single-subject experimental study with multiple baselines, six individuals with mild depression underwent daily sessions of facial electrical stimulation for 28 consecutive days. The stimulation was administered at two different sites, with three different baseline periods of 3, 6, and 9 days at each site. Specifically, three participants received electrical stimulation of the zygomaticus muscle, while the other three participants received electrical stimulation of the frontalis muscle. Visual analysis (diagrams and figures), within-phase examination, and between-phase examination were used to analyze longitudinal data using mixed model analysis (P < 0.05). Results: Mixed model analysis revealed significant changes in negative affect (P = 0.019), mood (P = 0.017), depression (P = 0.005), and symbol search (P < 0.001) among participants who received frontalis muscle stimulation. Additionally, the mood of participants who received zygomaticus muscle stimulation showed significant changes (P = 0.047) from pre-intervention to post-intervention. At the intervention and follow-up stages (one month after the last intervention session), all three participants who underwent frontalis muscle electrical stimulation met the standardized recovery criteria established by Segger et al. The reliable change index was measured at 8.46. A qualitative analysis of the depression scores revealed a significant difference in the post-intervention phase when frontalis muscle electrical stimulation was applied. Participants 4, 5, and 6 scored 9, 11, and 8, respectively. Conclusions: This preliminary study provides empirical evidence on using electrical stimulation of facial muscles to reduce negative mood and depression. Given the various factors that play a role, more research and focused controlled studies are needed to test these findings.

Reading others’ social appraisals after viewing an aversive film online impacts mood but not intrusive memories

Exposure to aversive footage online can affect our well-being, but to what extent does reading others’ appraisals of this content modulate our affective responses? In a pre-registered online study (N = 170), we used a digital trauma film paradigm as an analogue for the naturalistic exposure to aversive visual content online. We investigated whether online social reappraisal about the film influenced acute affective responses and subsequent intrusive memories. First, we examined whether the digital trauma film paradigm induced similar affective responses as in-lab experiments (within-subjects; change in negative mood and intrusive memories of the film during seven days). Participants reported a negative mood change and experienced intrusive memories of the film, extending findings from in-lab experiments. Next, we tested a social reappraisal manipulation that provides written comments from (fictitious) previous participants (between-subjects; reading positive, negative, or no comments) modulated participants’ affective responses. As predicted, relative to controls and negative comments, reading positive comments decreased negative mood. However, reading negative comments did not increase negative mood. Contrary to predictions, the social reappraisal manipulation did not modulate the number of intrusive memories. Findings suggest the benefit of positive social reappraisal for mitigating negative mood, but not intrusive memories following aversive film content online.

The association of negative mood with automatic and effortful facial expression mimicry.

The natural process of mimicking the facial expressions of others is well established, as are the deficits in this reflexive behavior for individuals with clinical disorders such as depression. This study examines the extent of this deficit in non-clinical individuals with high transient negative mood, and whether it extends to both automatic and effortful emotion expression behavior. One hundred and thirty-six participants were shown happy, sad, and neutral faces, while electromyography (EMG) recorded facial muscle responses. Automatic (reflexive) mimicry was assessed while participants simply viewed facially expressive photographs, while effortful mimicry was monitored when individuals were told to intentionally copy the expressions in the photographs. Results indicated that high levels of negative mood were primarily associated with deficits in effortful mimicry of happy expressions, although some similar evidence was found in automatic mimicry of happy faces. Surprisingly, there were also ties between negative moods and inaccuracies in effortful mimicry of sad expressions (but not automatic mimicry). Inaccurate automatic and effortful mimicry were also tied with lower self-reported social support and greater loneliness. These results indicate that even in healthy individuals, transient and minor changes in negative mood are tied to deficiencies in facial mimicry at both the automatic and effortful level.

Pain Catastrophizing Is Associated with a Pattern of Negative Emotional States and a Lack of Positive Emotional Priming

Abstract Pain catastrophizing (PC) is a predictor of pain outcomes that is typified by a host of negative changes in mood and cognition, and there is a need to continue defining PC's role in pain and daily life. This study sought to add to the body of literature on PC by investigating the influence of subconsciously presented cues on the interpretation of otherwise ambiguous stimuli. I assessed 216 participants for PC and completed questionnaires that quantified their emotional state and level of behavioral inhibition before and after being exposed to masked primers for either pain/negative emotion, neutral emotion, or happiness. Participants were then asked to interpret ambiguous stimuli (word stems). It was found that the presentation of unpleasant, pain-related masked images resulted in the generation of more negative words than pleasant, non-pain-related masked images. However, the pleasant images failed to result in lower levels of negative words for catastrophizers, indicating a bias to perceive negativity even in pleasant situations. PC was further found to be associated with more negative affect, greater behavioral inhibition, and higher levels of anxiety, pain, and depression. Catastrophizers reported significant negative emotional valence on several indices and did not benefit from masked priming for positive emotions compared to those with less PC. These findings may be useful in defining the parameters of future studies on PC and could be used by clinicians and physicians attempting to treat patients with chronic pain.

Emotional Eating: Psychosocial Bases, Accordingly Directed Treatment Design, and Longitudinal Effects in Women with Obesity.

Emotional eating (eating triggered by adverse mood) might be an important psychosocial variable to address to improve overwhelmingly deficient obesity treatment outcomes in women. However, emotional eating has rarely been focused upon in a systematic, evidence-based manner. Within Part 1 of this field-based study completed within community health-promotion centers the United States, a treatment protocol was developed targeting negative mood, body satisfaction, and self-efficacy to resist negative emotion-related eating (SE-NegEm), which were the significant psychosocial predictors of emotional eating found at baseline in the women participants with obesity. A comparison condition consisted of matched treatment time, but focused upon typical processes of providing education in healthy eating and exercise. Cluster sampling allocated participants to either the treatment group (n = 100) or comparison group (n = 86). In Part 2, overall improvements in mood, body satisfaction, SE-NegEm, and emotional eating were found to be significant, and significantly more pronounced in the treatment group. In parallel multiple mediation analyses incorporating aggregated data, changes from baseline-Month 3 and baseline-Month 6 in negative mood, body satisfaction, and SE-NegEm significantly mediated relationships between group and changes in emotional eating from baseline-Month 6 and baseline-Month 12, respectively. Changes in body satisfaction and SE-NegEm were significant independent mediators for 6-month change, with negative mood change additionally significant for 12-month change. Reduced emotional eating significantly predicted lost weight, which was greater in the treatment group (-5.8% vs. -0.9%). The present process of tailoring and testing treatment content based on earlier-identified predictors of emotional eating was supported.

The Effect Of Dysmenorrhea On Mood Changes In 2020 Yarsi University Faculty Of Medicine Students And According To Islamic Perspective

Background: Dysmenorrhea is defined as painful uterine cramps occurring during menstruation and is one of the most common causes of abdominal pain and menstrual disorders. Not all women who experience menstruation feel comfortable; this is caused by general disturbances such as mood swings, joint pain, and abdominal pain, which is called dysmenorrhea. Women with dysmenorrhea need knowledge about the effects of dysmenorrhea on mood changes. The effect of dysmenorrhea on mood in 2020 YARSI University Faculty of Medicine student is unknown.Methods: This type of research is descriptive-analytic with a cross-sectional study approach. The sample in the study consisted of students from the Faculty of Medicine at YARSI University, class of 2020, with 120 respondents. Data was collected by filling out a questionnaire to measure pain and mood changes, namely Numeric Rating Scale (NRS) and Four Dimensions Mood Scale (FDMS). The analysis was carried out univariately on each variable and bivariate to see the relationship between variables. Results: The results showed that YARSI University Faculty of Medicine students who experienced mild, moderate, and severe dysmenorrhea with negative mood changes, respectively, were 5 people (10.4%), 5 people (10.6%), and 14 people (56%). Mild, moderate, and severe dysmenorrhea with relaxation mood swings affected 10 people (20.8%), 31 people (66%), and 6 people (24%). Mild, moderate, and severe dysmenorrhea with positive mood changes, respectively, affected 33 people (68.8%), 1 person (23.4%), and 5 people (20%). The results of the Chi-Square analysis showed a relationship between the incidence of dysmenorrhea and mood swings.Conclusion: There is a relationship between the incidence of dysmenorrhea and mood swings in 2020 YARSI University Faculty of Medicine students.

Effects of rumination and distraction on inhibition

Background and objectivesRumination involves fixating on negative content, is associated with biases in inhibitory control, and typically worsens negative mood. In contrast, distraction attempts to engage attentional control and downregulate negative mood. To date studies have not dissociated the detrimental effects of rumination from beneficial effects of distraction on individuals’ ability to inhibit irrelevant negative information. Moreover, research has not examined the possible pathways connecting rumination and distraction, negative mood and inhibitory control. MethodsTo bridge these gaps, we report two studies that assess the effect of induced rumination versus distraction on inhibitory control among high ruminators. ResultsIn Study 1 distraction improved inhibition of negative content, whereas induced rumination impaired inhibition of negative content. Study 2 replicated Study 1 and demonstrated that the effect of distraction on inhibition of negative content was mediated by changes in negative mood. LimitationsOur studies are limited by small sample sizes and lack of measurement of possible long-term effects. ConclusionsOur findings provide preliminary evidence for an effect of mood on inhibition and not vice versa, among high ruminators. We discuss theoretical and clinical implications of these findings.

Energy Savings and Human Performance, Transition Towards Efficient Lighting in Commercial Buildings

Purpose: Evaluate human performance under LED lighting system in commercial building regarding:-Visual Performance (VP), Motor Performance (MP), Task Performance (TP), Cognitive Performance, Human Performance, and Work Life. To assess the direct effect between Cognitive Performance and Human Performance To identify the role of Circadian System (M1), and Discomfort (M2) between Cognitive Performance and Human performance. Theoretical framework: Driven lighting is presently the most reliable. As a result, determining all crops' light needs is complicated. Purposive sampling use to select the respondents. Floor office units and single office rooms required LED illumination. Because the entire population list was unavailable, 200 samples chose for the investigation. The study looked at an employee's cognitive and human performance. No relation between visual and cognitive performance. Pain impairs cognitive and motor functions. No discomfort affects work-life balance. However, the pain reduces human performance. Distress, eye pain, and weariness impede human performance. However, visual discomfort, visual message, glare, and flicker do. The study recommends assessing visual performance based on employee illumination discomfort. Design/Methodology/Approach:Driven lighting systems are now the most widely used and dependable in the world. Compact fluorescent light bulbs are used in India's current lighting systems for the most part. Even though there are a few small and medium-sized LED producers, there is no industry standard for LED production. As a result, estimating the amount of light all types of produce require is difficult. The goal of this research was to find out how LED illumination affects human performance. An organized questionnaire was utilized to gather information from employees of various government and commercial sector organizations. The research focused on the Trivandrum area because Trivandrum is Kerala's capital and home to most of the state's administrative offices. Respondents were drawn from government and private sector offices using a stratified random sampling approach. Offices were divided into floor office units and single office rooms, with LED lighting systems required in all of them. Two hundred samples were chosen for the study after the reliability and genuineness of obtained data were checked because the entire population list was unavailable. Findings: Research, Practical & Social Implications: As a result of this research, we set out to determine how well LED and conventional (linear fluorescent, compact fluorescent, and incandescent) lighting systems perform luminously, how well people perform, and how much they cost in the most common luminaire applications currently found in the environment. The popularity of LED lighting systems has overtaken that of all other kinds of fabricated luminaires. In contrast, linear and compact fluorescent luminaires are used in most Indian lighting systems now in use. No LED standards exist, despite just a handful of medium and small firms currently producing LED lights. As a result, establishing the precise illumination requirements for each product is challenging to do. Compare the environmental, technological, and economic factors to the alternatives now accessible to discover a better solution. Originality/value: Human performance is very much important in every sector and it’s depended on various multi-dimensional factors. Here the study has been analysed the direct and indirect effect between Cognitive Performance and Human performance of an employee. Simultaneously, study is saying that cognitive performance is not depending on the visual, and task performance. On the other hand, it could be seen that, Cognitive performance is affected by discomfort and the motor performance influence towards the Cognitive performance is positive but not significant. In the case of work life, it has no influence towards the human performance and also discomfort is influencing the human performance. While analyzing the mediation effect, it was found that, direct effect of Cognitive Performance will increase the Human Performance, but the existence of discomfort will reduce the human performance. Which means that negative mood change, visual discomfort, discomfort to visual message, Glare, Flicker, Eye pain, and fatigue are reducing the human performance. Based on the findings from the study, it could be seen that visual, motor and task performance is not influencing the cognitive performance, at the same time visual discomfort, discomfort to visual message, Glare, Flicker are decreasing their performance. hence, the study is suggesting that visual performance should be measure on the basis of various discomforts faced by the employee from their work place lightening.

Emotional changes following discrimination induction in gender- and sexuality-diverse adolescents.

Sexual and gender minority (SGM)-identifying adolescents are particularly vulnerable to negative psychological outcomes, including engagement in nonsuicidal self-injury (NSSI). However, little is known about why these relationships exist. We used experimental methods to test the psychological mediation framework in an online sample of 328 adolescents who reported female sex at birth and a range of sexual and gender identities. Participants reported on depressive symptoms, self-criticism (both self-report and implicit), NSSI, and discrimination. They also completed a discrimination-based mood induction to test emotional reactivity. At baseline, SGM participants reported higher levels of implicit and self-reported self-criticism, depressive symptoms, discrimination, and higher rates of NSSI compared with cisgender, heterosexual participants (ps < .03). Following the discrimination induction, SGM-identifying participants exhibited larger emotional reactivity compared with cisgender heterosexual participants, as measured by change in negative mood, F(1, 326) = 7.33, p = .01, ηp2 = .02, and state self-criticism, F(1, 326) = 4.67, p = .03, ηp2 = .014, but not implicit affect toward the self. This effect was associated with baseline depressive symptoms, self-criticism, NSSI history, and discrimination. Post hoc analyses revealed that participants who tended to reframe experiences of discrimination as opportunities for growth exhibited attenuated emotional reactivity to the induction; findings remained significant after adjusting for SGM status and event severity (ps < .001). Results indicate that adolescents identifying as SGM may experience elevated psychological distress compared with their cisgender heterosexual peers and that stigma-related stressors may increase emotion dysregulation and maladaptive cognitive styles, paralleling previously proposed psychological mediation models. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Learning to flourish in a new reality: a thematic analysis of couples’ experience of participation in a positive psychology intervention post-stroke

Purpose Explore the experiences of couples engaging in a positive psychology intervention post-stroke (ReStoreD: Promoting Resilience after Stroke in Dyads). Materials and methods This is a secondary analysis of qualitative data collected following an 8-week self-administered dyadic positive psychology intervention (Clinical Trial number: NCT03335358). Participants included dyads consisting of one partner who had a stroke at least three months prior and their cohabiting partner. Couples had to be community-dwelling and one or both had to report depressive symptoms. A thematic analysis was conducted on semi-structured feedback interviews from 26 dyads (n = 77 interviews). Results Two primary themes with multiple secondary themes were identified, depicting the experiences of couples post-stroke while engaging in the ReStoreD intervention. Primary and secondary themes included: changes in self (learning about the self, building new coping strategies, and acting with intention) and changes in the relationship (awareness of spouse, spending more positive time together, being more intentional in the relationship, and increased/improved communication). Conclusions Individuals and couples post-stroke often experience negative mood changes, poor health outcomes, and decreased participation. Implementation of ReStoreD activities in the clinical setting can be a valuable and impactful way to encourage and foster positive experiences and re-engagement post-stroke. Implications for Rehabilitation Through dyadic positive psychology intervention activities, rehabilitation professionals can build upon existing strengths and resources to encourage couples to increase their awareness and development of positive coping strategies as individuals and couples. Positive psychology intervention activities can be implemented by rehabilitation professionals at inpatient and outpatient settings through self-directed, low-cost, and time-efficient strategies to increase engagement in positive activities at home.

Family Matters: Trauma and Quality of Life in Family Members of Individuals With Prader-Willi Syndrome.

BackgroundPrader-Willi syndrome (PWS) is a potentially life threatening, genetic developmental disorder that requires lifelong medical treatment and behavioral management. PWS has a major impact on the patient's social environment. In this study, we have explored traumatic life events and symptoms of posttraumatic stress disorder (PTSD) in family members of individuals with PWS. We have also assessed quality of life in relation to trauma manifestations. In addition, we have evaluated demographic characteristics such as living setting of PWS patients as well as PWS symptom severity.MethodsData of this observational study were obtained by means of the Life Events Checklist DMS-5, the Posttraumatic Stress Disorder Checklist DSM-5, the abbreviated World Health Organization Quality of Life questionnaire, the Lancashire Quality of Life Profile questionnaire, and a short demographic inventory. The study sample includes 98 adults aged 19 to 80 years (M = 49, SD = 15), who are relatives of 69 individuals with PWS aged 0 to 58 years (M = 19, SD = 13). Participants were recruited via the two Dutch patient associations PWS and the Dutch Digital Center of Expertise PWS.ResultsLife time prevalence of traumatic events (93%) was higher in family members of PWS patients (“PWS relatives”) than in the general Dutch population (81%). Of those who reported any traumatic event, almost half reported PWS-related events. The prevalence of probable PTSD was higher in PWS relatives (12.1%) than the general lifetime prevalence of PTSD (worldwide, and in the Netherlands 7.4%). Predominant trauma symptoms in PWS relatives were “negative changes in arousal and reactivity” and “negative changes in cognition and mood;” both significantly negatively related to quality of life. Symptom severity of PWS individuals, as well as the associated trauma symptom severity of their relatives increased with age of the PWS individual. The presence of trauma symptoms was less frequent among relatives of PWS individuals living in a care facility.ConclusionsHaving a relative with PWS is associated with higher prevalence of traumatic experiences and greater vulnerability to PTSD. Raising awareness in health care professionals of trauma symptoms in PWS relatives may contribute to effective treatment of their psychosocial stress. In addition, timely interventions might prevent family members from developing psychopathology like PTSD.

0017 Murder on the Midnight Express: Nocturnal Wakefulness and Homicide Risk

Abstract Introduction There is a nocturnal peak in incident suicide risk after adjusting for population wakefulness (Perlis et al., 2016; Tubbs et al., 2020). This peak in risk is hypothesized to result from a series of negative changes in mood, reward processing, and executive function that occur at night and increase the propensity for dysregulated and violent behaviors. Although the unadjusted incidence of dying by homicide is elevated at night, no existing studies of time-of-day and death by violent crime have adjusted for population wakefulness. Methods Data from 48,486 homicide victims with a known time of fatal injury were collected from the National Violent Death Reporting System (NVDRS) for 2003-2017, tabulated by clock hour, age, sex, race, and ethnicity, and combined with population wakefulness data from the American Time Use Survey (ATUS) for the same years. Homicide counts were additionally characterized by the proportion of cases with blood alcohol level (BAL) of 0, &amp;lt;80mg/dl, or ≥80mg/dl at autopsy and modeled using robust Poisson regression with population wakefulness entered as an offset term, thus producing hourly incident risk ratios (IRR). Results Homicide counts were lowest in the morning (6AM-7AM) and highest at night (10PM-11PM). After adjusting for population wakefulness, the incident risk for death by homicide was elevated between 10PM and 5AM compared to the 24-hour average, with the highest risk between 2AM (IRR: 8.25 [6.62-10.3]) and 3AM (IRR: 7.22 [6.04-8.64]). Moreover, the adjusted risk of dying by homicide was significantly greater at night for those with a BAL≥80mg/dl, such that the risk at 2AM was 13.8-fold greater than the 24-hour average (IRR: 13.8 [10.6-18.1]). Conclusion The risk of homicide death is higher at night after adjusting for population wakefulness and especially among those with alcohol intoxication. Although homicide victims do not choose when to die (unlike suicide victims), neurophysiological changes at night may promote risky behaviors or put victims in more dangerous circumstances than they would be otherwise. Future research should examine sociodemographic, clinical, and circadian risk factors for death by homicide, as well as examine time-of-day patterns in other violent crimes. Support (If Any)

Secondary Traumatic Stress and Moral Injury in Maternity Care Providers: A Narrative and Exploratory Review.

IntroductionA significant percentage of maternity providers have experienced secondary traumatic stress following a traumatic birth. Previous studies identified it as an issue, but this literature review is 5–9 years old. In addition, the construct of moral injury has significantly increased our understanding of secondary trauma for military veterans. In the wake of COVID-19, this construct also applies to healthcare providers.ObjectivesThe present article updates these reviews and compares findings for three groups: labor and delivery nurses, midwives, and obstetricians. The second portion of this review re-examines previously published qualitative research to determine whether moral injury might more accurately describe the experiences of maternity personnel.MethodsA comprehensive review of PubMed, Scopus, Web of Science, PsychINFO, and CINAHL was conducted in June 2021 using search terms such as compassion fatigue, secondary trauma, moral injury, labor and delivery, nurses, midwives, and obstetricians. Forty articles were identified, but only 16 focused on secondary trauma or moral injury.ResultsSecondary trauma is a significant concern affecting at least 25% of maternity staff. However, some countries have very low rates, which correspond to low rates in childbirth-related trauma in mothers. Secondary trauma can lead to several symptoms, including re-experiencing, avoidance, negative changes in mood and cognitions, and hyperarousal, which can cause significant impairment. As a result, many providers decide to leave the field in the wake of a traumatic birth. The incidence of moral injury is unknown, but a re-examination of previously published qualitative data suggests that this construct, generally used to describe combat veterans, does describe some of what providers have reported. Acts of omission, i.e., failure to stop the harmful acts of others had long-term negative effects on labor and delivery nurses, consistent with data from military samples. Two possible mediators were proposed: hierarchical and gendered relationships in hospitals and agency of care.ConclusionThe effects of traumatic birth on providers can be severe, including possible psychological sequelae, impaired job performance, and leaving the field. Moral injury expands upon the construct of secondary traumatic stress. This construct better describes the experiences of maternity staff in non-primary roles who witness traumatic births and are often haunted by events that they could not prevent, but often question whether they should have.