The article presents the vitamin and mineral preparation «Biotan 3Z" which includes micro- and macroelements in the form of water-soluble salts, namely Calcium, Phosphorus, Magnesium, Iron, Copper Manganese, Copper, Cobalt and Manganese. It also contains many vitamins (aspartic acid, glutamic acid, vitamin A, E, B1, PP) and essential amino acids - rich in methionine, lysine, arginine, histidine, tyrosine, phenylalanine, isoleucine, leucine, valine, cystine, tryptophan, glycine, proline, threonine and serine, which are necessary for the normal functioning of the body. Due to this veterinary drug the level of diseases of domestic animals decreases, their productive qualities increase. This drug accelerates the growth of animals. Vitamin and mineral preparation «Biotan 3Z" reduces the incidence and mortality of animals. Prevents diseases that originate from changes in housing conditions or occur against the background of metabolism or lack of vitamins and minerals.
 When using this drug in bitches, the biochemical and morphological parameters of the blood of these animals were analyzed. Significant changes in blood parameters such as erythrocytes, hemoglobin, hematocrit, total protein, before and after administration of the drug in various forms of manifestation have not been established. There was only a slight increase in erythrocytes from 6,6±0,2 thousand / ml to 7,8±0,4 thousand/ml, as well as a slight increase in hemoglobin from 120±3,8 g/l to 146±6,8 g/l. Vitamins and minerals contained in the fed drug had a positive effect on metabolism in the mother and fetus, as evidenced by changes in blood creatinine, which at 14 weeks before delivery was 127,6 μmol/l and on the first day of delivery in the experimental group increased to 135.8 μmol/l.
 The addition of a vitamin-mineral preparation to the main diet in some way affected the metabolism and biochemical composition of the blood of the bitches of the experimental group. It was expressed by an increase in the physiological limits of glucose, total protein, albumin, creatinine, cholesterol, total calcium, inorganic phosphorus and a decrease in globulins, bilirubin and AST. The concentration of urea, triglycerides and LF activity almost did not change.
 Feeding of vitamin-mineral preparation «Biotan 3Z» to bitches before childbirth affected the content in the blood of experimental animals of total calcium and inorganic phosphorus, the concentration of which increased by 0,2 mmol / l compared to baseline, and 0,2 and 0,3 mmol/l – with the control group after the experiment. Vitamin and mineral preparation «Biotan 3Z» is of interest for veterinary medicine and therefore it is advisable to continue its further clinical study.