Changes In Practice Research Articles

Academic Degrees for Monks: Sera Je and the Challenges of Integrating Tibetan Buddhist Monastic Education into the Indian University System

Although there have been concerted efforts to integrate Tibetan Buddhist monastic education into the Indian university system since the 1960s, the attainment of academic accreditation has tended to require significant curricular trade-offs. The majority of Tibetan Buddhist monastic colleges have therefore eschewed the potential advantages of academic accreditation—including greater opportunities for monastic graduates in universities and other secular contexts—in order to preserve the rigour of traditional scholastic programmes. However, through its affiliation to the University of Mysore in 2022, the Geluk monastery of Sera Je is now able to award accredited Bachelor of Arts (BA) degrees even without making significant changes in practice to its traditional curriculum and pedagogy. This article examines the structure and content of Sera Je’s new programmes and contextualises what may prove to be a landmark development against the backdrop of previous attempts to negotiate the boundary between Tibetan Buddhist monastic education and university education in India. It suggests that the accreditation of research programmes raises further challenges in addition to those associated with the accreditation of taught programmes. Nonetheless, the urgency of solving these longstanding issues appears to have been heightened by a developing crisis in Tibetan Buddhist monastic recruitment. In investigating the topic of academic accreditation, this article throws light on an issue that has driven notable evolutions in Tibetan Buddhist monastic education in India but has previously received little scholarly attention.

Life Cycle Assessment of Consumption Patterns – Understanding the links between changing social practices and environmental impacts

As we are still not on track to achieve environmental sustainability through technological change, we need to further stress the importance of understanding routinized types of behaviour by private households and the environmental assessment of corresponding consumption of resources. Social practice theories allow us to understand the constitution of human activity and its embeddedness in society. In transformation research, the relevance of social practice theories has been recognized. However, there is still a lack of understanding regarding the conditions under which practices change substantially and what kinds of tools and governance approaches are suitable to foster change in social practices. We therefore propose a novel way to address the transformation of consumption patterns of private households by a) connecting social practice theories to life cycle assessment for a quantitative environmental evaluation of transformation processes and b) using narrative approaches to understand the links between several social practices and conditions for change. An illustrative study of a bottom-up neighbourhood initiative shows how specific meanings and values (expressed, for example, through meanings of “enough”) affect several social practices from different consumption categories (nutrition, daily mobility, travelling). Environmental assessments further show that changing social practices across consumption categories can substantially decrease environmental pressures from private household consumption, especially in the field of nutrition. The understanding of how various social practices are connected in a nexus through narratives embodying deeper meanings point to novel ways of fostering change and the relevance of social practices related to urban or neighbourhood initiatives as an entry point to a more sustainable way of living.

Using an evidence-informed reflection tool to develop understandings of feedback talk

ABSTRACT Research-based and practical reflection tools can enable systematic analysis of practice and contribute to deeper understandings of classroom processes. An empirically based, evidence-informed reflection tool was developed to support teachers to recognise feedback talk and how it is built into classroom interactions. The tool, titled the feedback talk framework, enabled teachers to reflect on their feedback talk and effect changes in practice and feedback literacy. The feedback talk framework was refined through a survey and semi-structured interviews with teachers for use as a reflection tool and resulted in three overarching feedback talk themes: informing, confirming and validating, and questioning. Results illuminated how teachers used the tool to identify and reflect on feedback talk, strengthening our argument that using an empirically derived feedback talk framework can support evidence-based approaches to teacher reflection. Suggestions and implications for the utility of the reflection tool in a range of contexts are then provided.

Preparing the Next Generation of Integrative Organismal Biologists.

Pursuing cutting edge questions in organismal biology in the future will require novel approaches for training the next generation of organismal biologists, including knowledge and use of systems-type modeling combined with integrative organismal biology. We link agendas recommending changes in science education and practice across three levels: Broadening the concept of organismal biology to promote modeling organisms as systems interacting with higher and lower organizational levels; enhancing undergraduate science education to improve applications of quantitative reasoning and modeling in the scientific process; and K-12 curricula based on Next Generation Science Standards emphasizing development and use of models in the context of explanatory science, solution design, and evaluating and communicating information. Out of each of these initiatives emerges an emphasis on routine use of models as tools for hypothesis testing and prediction. The question remains, however, what is the best approach for training the next generation of organismal biology students to facilitate their understanding and use of models? We address this question by proposing new ways of teaching and learning, including the development of interactive web-based modeling modules that lower barriers for scientists approaching this new way of imagining and conducting integrative organismal biology.

Context-dependent agricultural intensification pathways to increase rice production in India

Yield gap analysis is used to characterize the untapped production potential of cropping systems. With emerging large-n agronomic datasets and data science methods, pathways for narrowing yield gaps can be identified that provide actionable insights into where and how cropping systems can be sustainably intensified. Here we characterize the contributing factors to rice yield gaps across seven Indian states, with a case study region used to assess the power of intervention targeting. Primary yield constraints in the case study region were nitrogen and irrigation, but scenario analysis suggests modest average yield gains with universal adoption of higher nitrogen rates. When nitrogen limited fields are targeted for practice change (47% of the sample), yield gains are predicted to double. When nitrogen and irrigation co-limitations are targeted (20% of the sample), yield gains more than tripled. Results suggest that analytics-led strategies for crop intensification can generate transformative advances in productivity, profitability, and environmental outcomes.

Do Half of Orthopaedic Surgeons Change Jobs within Their First 2 Years?: An Analysis Using the American Board of Orthopaedic Surgery Database.

The claim that "50% of orthopaedic surgeons leave their first job within 2 years" did not originate from evidence. The purpose of this study was to investigate practice change rates among board- eligible orthopaedic surgeons using the American Board of Orthopaedic Surgery (ABOS) database. We utilized information provided by orthopaedic surgeons taking the ABOS Part II Examination across 6 different years. Surgeons who trained outside of the United States and members of the uniformed services of the U.S. were excluded. Move rates within 2 years of starting practice and before the candidate's Part II examination were determined. All surgeons were then subcategorized as having followed a traditional or nontraditional certification timeline based on whether they took Part II of the examination within 2 practice years after becoming board-eligible. Candidate-specific variables were analyzed according to whether the surgeon did or did not change practices. Among 3,784 orthopaedic surgeons, 215 (5.7%) left their first practice within 2 years. On average, candidates sat for the Part II examination at a mean (and standard deviation) of 2.1 ± 1.1 years (range, 0.7 to 31.9 years) after reporting their first practice location. Seventy-six percent of surgeons took the Part II examination within a traditional timeframe. On average, nontraditional candidates left their first practice at a significantly higher rate than traditional candidates (20.5% versus 1.3%; p < 0.001), changed practices more often (1.5 versus 1.2 moves; p = 0.021), and moved farther (500.1 versus 304.4 miles; p = 0.023). Fellowship training and/or Part II examination subspecialty were not strongly associated with a surgeon leaving his or her first practice. While it is possible that >5.7% of orthopaedic surgeons leave their first job during their early career, it is unlikely that many relocate within 2 years. This is especially true among orthopaedic surgeons pursuing ABOS certification within a traditional timeframe.

Recognizing Identity Fluidity in Demographic Research

AbstractStandard demographic research has typically constrained the existence of identity fluidity, assuming that demographic categories such as race or ethnicity and sex or gender should be static across the life course and measuring them as such. However, recent research and changes in data collection practices highlight the limitations of this approach by demonstrating fluidity in both racial and gender identities that rivals levels of fluidity in other identity categories, such as sexual orientation, that are more commonly seen as changeable over time. This review examines what is known about current levels of fluidity in gender, sexual orientation, and racial identities as well as known correlates and consequences for research on inequality, based primarily but not exclusively on research conducted in the United States. The implications of fluid identities for data collection and analysis, as well as prospects for future levels of fluidity, are also discussed.

Hypertensive Disorders of Pregnancy: A Window into Breastfeeding Outcomes in Varied Healthcare Systems

Varied hospital systems demonstrate diverse and often very different approaches to patient care. This may best be analyzed by looking at specific disorders and outcomes in a population with these disorders. As one such lens, hypertensive disorders of pregnancy (HDPs) continue to pose a severe health risk for mothers and infants, and breastfeeding outcomes play a crucial role in determining long-term maternal and fetal health. This pilot study investigated breastfeeding outcomes in two hospitals, as representatives for differing healthcare systems, among patients diagnosed with HDPs. Data were collected for 12 months at two hospitals, one private and one military, on 729 patients diagnosed with HDPs. Data were analyzed for infant maturity at birth and breastfeeding outcomes. Most participants (83.2%) stated their intention to breastfeed for the first six months of life. By hospital discharge, only 56% (p = 0.0001) of the private hospital participants were breastfeeding compared to 65% of the military hospital participants. In addition, while 69% of infants were born before term, more infants were born before term at the private hospital (71%) than at the military hospital (65%), with 37% (private) and 42% (military) of preterm infants breastfeeding at hospital discharge. Significant differences existed between these two hospital systems in the number of those initiating breastfeeding and breastfeeding at hospital discharge. The military hospital was more successful in assisting these high-risk women in meeting their breastfeeding intentions. Changes in hospital practices, such as metrics and incentivization, focusing on breastfeeding support, could improve the rate of breastfeeding at hospital discharge and impact long-term health outcomes.

Empowering Midwives in Humanitarian Settings: Integrating Heat-Stable Carbetocin and Tranexamic Acid into Postpartum Hemorrhage Training.

Maternal mortality remains extremely high in fragile settings, with hemorrhage as the leading cause. This study describes a new model for more effective training on postpartum hemorrhage (PPH) prevention and treatment. Using a low-dose (of information) and high-frequency (of repetitions) approach (LDHF), the strategy comprised an introductory webinar, self-paced study, 2-day in-person workshops, cascade training, continuous facility-based skills drills, and a WhatsApp community of practice and supervision (CoP). Innovations consisted of the practical, midwifery-centered, and short-duration training, and the integration of tranexamic acid (TXA) and heat-stable carbetocin (HSC) into existing modules from the "Bleeding-After-Birth-Complete" toolkit. Effects were assessed through mixed-methods evaluation. Confidentiality and "do-not-harm" principles were respected. Nine training sessions were conducted in South Sudan and Uganda combined, engaging 126 participants. Average knowledge increases of 21% in South Sudan and 18% in Uganda were recorded. Feedback also indicated changes in practices and attitudes: enhanced competency, teamwork, clinical protocols adherence, appreciation for midwife-led practical sessions, the LDHF method, and continuous support through the WhatsApp CoP. In post-workshop action plans, facility teams outlined steps to apply acquired knowledge and skills. These included training colleagues, establishing quality improvement projects, conducting skill drills, ensuring job aid visibility, and systematically reporting on PPH in the data collection templates of the facilities. This case study highlights the value of a practical, LDHF refresher training strategy. This strategy bolstered providers' skills, knowledge, and confidence in using HSC and TXA for PPH prevention and treatment. Findings can guide future training in similar fragile, low-resource, and humanitarian settings. Strengthening midwifery leadership, fostering interdisciplinary collaboration, and using the LDHF training approach can contribute to resilient health systems and taskforce, aligning with global efforts to reduce maternal mortality.

Oncology Clinicians' Perspectives of a Remote Patient Monitoring Program: A Multi-Modal Case Study Approach.

Remote patient monitoring (RPM) aims to improve patient access to care and communication with clinical providers. Overall, understanding the usability of RPM applications and their influence on clinical care workflows is limited from the perspectives of clinician end users at a cancer center in the Northeast, United States. Explore the usability and functionality of RPM and elicit the perceptions and experiences of oncology clinicians using RPM for oncology patients after hospital discharge. The sample included 30 of 98 clinicians (31% response rate) managing at least five patients in the RPM program and responding to the m-Health Usability between March 2021- October 2021. Overall, clinicians responded positively to the survey. Item responses with the highest proportion of disagreement were explored further. A nested sample of five clinicians who responded to the study survey (30% response rate) participated in interview sessions conducted from November 2021 to February 2022, and averaged 60 minutes each. Survey responses highlighted that RPM was easy to use and learn and verified symptom alerts during follow-up phone calls. Areas to improve identified practice changes from reporting RPM alerts through digital portals and its influence on clinicians' workload burden. Interview sessions revealed three main themes: clinician understanding and usability constraints, patient constraints, and suggestions for improving the program. Subthemes for each theme were explored, characterizing technical and functional limitations that could be addressed to enhance efficiency, workflow, and user experience. Clinicians support the value of RPM for improving symptom management and engaging with providers. Functional changes to enhance the program's utility, such as input from patients about temporal changes in their symptoms and technical resources for home monitoring devices.

Mission-oriented innovation for sustainable polymers in liquid formulation.

Industrial chemical producers and formulators are increasingly conscious of their responsibility in stewarding planetary resources and minimizing harm to the environment. In 2019, the Royal Society of Chemistry (RSC) engaged an industry task force from across the value chain to drive technical research to classify a new class of polymer-polymers in liquid formulation (PLFs). Building on this, the task force called for step change in sustainability practices for PLFs and instigated a design and development process to identify research themes and priorities that could accelerate innovation in this area. However, a key challenge was that as a novel classification, PLFs were largely unknown outside the chemistry community and entirely absent from the mainstream research agenda. To establish the demand-pull requirements of the value chain for sustainable PLFs, the RSC used a 'mission-oriented' innovation framework to enable the taskforce to co-design an ideal-type portfolio of research and innovation projects, and to set out a realistic roadmap for transition. This perspective article presents a summary of the activities carried out by the task force in its pursuit of mission-oriented innovation for PLFs and describes the strategic design method used to enable cross-value chain consensus on action for PLF sustainability, build system-wide innovation ecosystems and explore common-good scenarios. This article is part of the discussion meeting issue 'Green carbon for the chemical industry of the future'.

Health Education for Sustainable E-Waste Management

A combination of ever-increasing device usage and lightning-fast technological advancements has led to a critical problem: electronic waste. One technique to encourage people to dispose of their electronic waste in a more sustainable fashion is to raise their level of green literacy. Using a literature review approach, this study examines green literacy programs as they pertain to e-waste management. After that, it evaluates the programs' effectiveness and makes recommendations for further developments. This publication uses a thorough literature review technique as its research method. The scholarly sources used were journals, academic books, research reports, and policy documents. The selection of sources was based on their relevance, credibility, and contribution to understanding key themes related to green literacy, public health education, and behavior change in e-waste management practices. Additionally, the analysis focused on the intersection between educational interventions, awareness campaigns and global health initiatives, especially those targeting vulnerable populations such as children and pregnant women. The findings demonstrate that while green literacy can raise public knowledge and comprehension of the significance of responsible e-waste management, there are still obstacles to its widespread adoption. By using social media, communities, and educational institutions, green literacy has the potential to raise awareness about the risks of e-waste and the significance of recycling. However, challenges such as public apathy and limited access to recycling facilities continue to impede the implementation of green literacy. The community, along with the governmental and private sectors, must work together to address these issues and encourage the sustainable disposal of electronic trash. Ongoing education and awareness efforts utilizing many communication platforms, including social media, the media, and educational programs in communities and schools, are necessary to improve e-waste management. In order to create easily accessible recycling facilities and launch programs that reach different societal levels, the government must collaborate with the commercial sector and non-governmental organizations.

Impact through engagement? A critical self-reflection on the engaged journalism exchange

Journalism studies scholars have increasingly focused on finding ways to improve the profession and practice they have dedicated their academic careers to better understanding. This critical self-reflection reviews the ways that we have attempted to make our own academic work impactful on journalistic practice. We discuss the challenges, opportunities, successes, and failures of our efforts to both increase the impact of our academic research among journalism professionals, as well as to build better connections with journalists and publics so that we can better inform our research questions and priorities. Our efforts have been difficult to maintain, and their impact has been all but impossible to assess. Our experiences suggest that journalists rarely have the time or resources to listen and act on assessments from academics, and academics rarely have the time, resources, incentives, or patience to find the best paths to sharing what they learn in ways that may lead to change in journalism practices'. In light of these circumstances, we argue that the questions and obstacles journalism scholars face when it comes to improving the impact of their work among media practitioners and community members eerily mirrors the questions and obstacles journalists face when it comes to improving the impact of their work among the public. We conclude by calling for more humility, honesty, and help when it comes to efforts to bridge the gap between journalism studies and practice.

Transforming Communication in the Wake of COVID-19: Overcoming Challenges and Shaping the Future

Aims: This study aims to investigate how the COVID-19 pandemic has transformed communication practices, focusing on the challenges encountered, adaptive strategies employed, and future directions in communication. Study Design: This research employs a qualitative study design utilizing in-depth interviews to capture the experiences and perspectives of individuals and organizations. Place and Duration of Study: The study was conducted remotely, with interviews taking place from February 2024 to April 2024. Methodology: The research involved in-depth interviews with participants across various sectors to explore the impact of the pandemic on communication. Participants discussed technological barriers, emotional and psychological challenges, and their adaptive strategies. The interviews were analyzed thematically to identify key patterns and trends. Results: The study reveals that technological barriers, such as connectivity issues and difficulties with digital platforms, significantly affected communication quality. Participants reported increased anxiety and communication fatigue as major emotional and psychological challenges. Despite these issues, there was a notable shift towards digital tools, the establishment of new communication norms, and changes in work and social practices. The findings indicate a continued reliance on digital technologies, the rise of hybrid communication models, and an increased focus on digital literacy and emotional well-being. Conclusion: The study highlights the need for ongoing adaptation in communication practices and further research to address the evolving landscape of communication in a post-pandemic world. The findings underscore the importance of improving digital infrastructure, supporting emotional well-being, and fostering digital literacy.

Machine Learning Approach to Investigate High Temperature Corrosion of Critical Infrastructure Materials

Degradation of coatings and structural materials due to high temperature corrosion in the presence of molten salt environment is a major concern for critical infrastructure applications to meet its commercial viability. The choice of high value coatings and structural (construction parts) materials comes with challenges, and therefore data centric approach may accelerate change in discovery and data practices. This research aims to use machine learning (ML) approach to estimate corrosion rates of materials when operated at high temperatures conditions (e.g., nuclear, geothermal, oxidation (dry/wet), solar applications) but geared towards nuclear thermochemical cycles. Published data related to materials (structural and coatings materials), their composition and manufacturing, including corrosion environment were gathered and analysed. Analysis demonstrated that random forest regression model is highly precise compared to other models. Assessment indicates that very limited sets of materials are likely to survive high temperature corrosive environment for extended period of exposure. While a higher quality and larger dataset are required to accurately predict the corrosion rate, the findings demonstrated the value of ML’s regression and data mining capabilities for corrosion data analysis. With the research gap in material selection strategies, proposed research will be critical to advancing data analytics approach exploiting their properties for high temperature corrosion applications.Graphical

Abstract B115: Intensive Course in genetic cancer risk assessment: Empowering clinicians, expanding clinical knowledge, and elevating care in underserved populations

Abstract Background: Despite efforts to integrate genetic cancer risk assessment (GCRA) services into mainstream medicine, the dearth of healthcare providers adequately trained in clinical cancer genetics remains a significant barrier to care, particularly in underserved communities. Since 2001, City of Hope has helped address this need through a distance mediated lntensive Course (IC) and Clinical Cancer Genomics Community of Practice (CCGCoP), with a focus on training and supporting clinicians who deliver care to underserved patient populations. Here we report on the reach, education, and practice outcomes from the past five annual cohorts of the IC in its pursuit to expand GCRA care to underserved areas and minority populations. Methods: Practice catchment area and patient population data were collected on the course application. Cancer genetics knowledge was assessed at baseline and immediate post-course; professional self-efficacy and practice changes were measured at baseline, immediate, and 12 months post-course. Results: Of 762 participants from five IC cohorts (2020-2024), 566 (74%) indicated they provide all or part of their care in an underserved area and/or to minority populations; 55 (10%) practice outside the U.S. Of these 566 clinicians, mean pre-to-post course knowledge scores increased 59%, and mean pre-to-post self-efficacy scores increased by 38%. Of 195 participants who completed a one-year post-course practice survey, 68 (35%) did not practice GCRA at baseline, of whom 61 (88%) reported implementing GCRA into their practice one-year post-course. Of 126 participants who were practicing GCRA at baseline, 55 (44%) reported an increase in their GCRA patient volume at one-year post-course. Open-ended feedback revealed that participants highly valued IC training and ongoing CCGCoP support for building and sustaining their GCRA skills, resources, and practices. Conclusions:Results demonstrate the efficacy of distance-mediated training and ongoing practice support in enhancing clinician competencies and knowledge of practicing GCRA therefore increasing access to GCRA services for underserved and minority patient populations. Efforts are underway to leverage the resources of the IC and CCGCoP to develop a more flexible, cost-effective course model and collaborate with champions to increase access to best practices in GCRA in diverse underserved settings across the US and internationally. Citation Format: Dev Tanna, John Luna, Alex Capasso, Kathleen Blazer. Intensive Course in genetic cancer risk assessment: Empowering clinicians, expanding clinical knowledge, and elevating care in underserved populations [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr B115.

Abstract C041: A systematic review of cardiovascular health among cancer survivors

Abstract Purpose: The most common non-cancer cause of death among cancer survivors is cardiovascular disease. Health behaviors (e.g., diet, physical activity, sleep, smoking) and health factors (e.g., blood pressure, hemoglobin A1C, cholesterol) associated with cancer mortality are also associated with cardiovascular mortality. The American Heart Association has termed these behaviors and factors “cardiovascular health” (CVH) or “Life’s Essential 8,” providing a metric to determine poor, intermediate, and high (ideal) CVH. Less than ideal CVH is associated with higher cancer mortality; however, little is known about the CVH of cancer survivors. The purpose of this systematic review is to examine the extant literature on CVH among cancer survivors. MethodsIn accordance with PRISMA guidelines, we are systematically examining cardiovascular health among cancer survivors (including patients) within PubMed, Scopus, CINAHL, and Embase databases without date limitations. Two reviewers are accessing articles at each level of review to determine concordance with inclusion criteria, coming to consensus via a shared discussion. Data from studies that meet inclusion criteria will be abstracted, assessed for risk of bias. and synthesized to understand themes of CVH among cancer survivors. Results To date, we have retrieved 1,990 studies from the named databases. Preliminary review of the title and abstracts suggests that CVH as a metric may be seldom used within extant literature. This review is ongoing. Conclusion: Given the co-morbid and iatrogenic nature of cardiovascular disease among cancer survivors, it is important to understand metrics that can be applied to both identify cancer survivors with increased risk of poor outcomes and educate/empower cancer survivors to make modifiable changes to reduce their risk. This review will provide much needed evidence to support future research, practice changes, and policy implications to support the long-term health of cancer survivors. Citation Format: Miriam A. Miles, Le’Andrea Anderson-Tolbert, Abigail A. Ninson, Cha-Breia Means, Tuchondriana Smith, Reagan Coleman, Laura Rogers, Joshua Joseph, Timiya S. Nolan. A systematic review of cardiovascular health among cancer survivors [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr C041.

Abstract B027: Adapting communication resources for clinic staff in a multisite FQHC to improve HPV vaccination encounters with Spanish-speaking parents of adolescents

Abstract Introduction: Adopting evidenced-based strategies (EBS) targeting clinic staff in safety-net settings can improve adolescent HPV vaccination rates. Still, adaptations of EBS are needed to reach racial/ethnic minority patients and families effectively. As part of a larger implementation study on HPV vaccination, we examined and addressed adaptation needs for HPV vaccine communication resources to support clinic staff serving Hispanic adolescent FQHC patients. Methods: In October 2022-January 2023, we partnered with a large multi-site FQHC in Los Angeles, CA to deliver two clinic staff trainings designed to i) improve HPV knowledge and communication strategies; and ii) discuss HPV vaccine workflow. Informed by the Practice Change Model, we completed baseline qualitative interviews with clinic team members (providers, clinic staff, and leadership) and provider and clinic staff surveys to inform the development, implementation, and adaptation of clinic staff training on HPV vaccine knowledge and communication strategies. We then conducted site visits and key-informant interviews with clinic staff immediately post-training. Notes from site visits and key-informant interviews were transcribed to identify potential barriers to adoption and opportunities for adaptation. Results: Baseline data indicated 95% of clinic staff identified as Hispanic and 94% reported speaking a language other than English. Notes from site visits and key-informant interviews with clinic staff indicated clinic staff identified the need for Spanish language messaging to communicate HPV and cancer prevention messages to monolingual Spanish families. As a result, we adapted Spanish-language messages from the 2023 Health Resources and Services Administration toolkit and American Cancer Society to develop a handout with scripts that address top concerns about HPV vaccination with monolingual Spanish-speaking parents of adolescents to that were identified from baseline data collection. Bilingual-bicultural staff then validated messages and confirmed cultural relevance. Developed materials were then presented to clinic leadership to review and suggest further refinement before delivering them to clinic staff. Discussion: Key-informant interviews and post-training site visits played an important role in identifying opportunities to adapt EBS designed to improve HPV vaccination among culturally diverse patients. To better serve diverse communities disproportionately impacted by HPV-associated cancers, clinic staff need resources with HPV vaccine communication messages available in languages that reflect the needs of their patient population. Citation Format: Samantha Garcia, Adrienne Martinez-Hollingsworth, Sheila Salinas Navarro, Sharon Hudson, Zehui He, Emily Dang, Lawrence Palinkas, Lourdes Baezconde-Garbanati, Jennifer Tsui. Adapting communication resources for clinic staff in a multisite FQHC to improve HPV vaccination encounters with Spanish-speaking parents of adolescents [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr B027.

Peripheral neuroimmunological diseases - Neuropathological insights and clinical perspectives

This article deals with peripheral neuroimmunological diseases and briefly outlines the currently most important aspects and treatment developments. Idiopathic inflammatory myopathies have different mechanisms of development, manifestations and prognoses. New classification systems and more specific treatment concepts have been developed. The IIMs include different subgroups. These entities can have specific autoantibodies. Diagnostically, amuscle biopsy is generally desirable for aprecise diagnosis and is essential in unclear cases. Primary systemic vasculitides can be divided into different groups based on the predominant pattern of involvement, while secondary vasculitides and single organ vasculitides are also differentiated. Vasculitic myopathy cannot be equated with myositis and areliable distinction is currently only possible by a muscle biopsy. Treatment concepts should be developed on an interdisciplinary basis. Chronic inflammatory demyelinating polyneuropathy is the most frequent immune-mediated neuropathy and is characterized by apredominant demyelination of the motor and sensory nerves. The disease course runs in phases or is progressive and leads to significant disability and reduction in quality of life, despite current standard treatment. Novel treatment approaches are currently undergoing clinical trials. Myasthenia gravis, with the leading symptom of exercise-induced muscle weakness, is caused by autoantibodies against structures of the neuromuscular endplate. Autoantibody testing is the most important pillar in the diagnosis and is now also increasingly guiding treatment decisions. Overall, peripheral neuroimmunological diseases represent aheterogeneous group. Increasing knowledge of the pathophysiology is the key to numerous developments in diagnostics and treatment, which could lead to far-reaching practical changes in the future.

The call for hybrid work arrangement post-pandemic

COVID-19 has led to abrupt changes in work norms and practices. Despite receding pandemic restrictions, the popularity of remote or hybrid work has not subsided. As employees around the world continue to call for more flexibility and autonomy in the way they work, human resource leaders must continuously consider and evaluate decisions based on ever-changing sentiment, balancing the interests of employees and employers alike. In this perspective article, we review the current state of work in the Southeast Asian region, focusing on Malaysia, Singapore, Indonesia, the Philippines, and Thailand, and present preliminary results from a region-wide mental health assessment that was conducted in late 2022. We argue for the continuation of hybrid work in the region and elaborate on the mental health risks that come with remote working.