The article was prepared on the basis of a report made at the scientific and practical conference «Organization of deratization measures in modern conditions, topical issues of disinfection activities in the conditions of medical organizations of various profiles,» held May 15-16, 2024 in St. Petersburg. Purulent-septic infections cause damage to the health and life of patients, as well as cause social and economic damage. Disinfection and sterilization measures are one of the most important measures in the system of anti-epidemic measures aimed at breaking the mechanism of transmission of infectious agents, which leads to the cessation of the development of the epidemiological process and the spread of ISMP. Keywords: hospital, purulent-septic infections, central sterilization department, diabetes mellitus, preventive measures, anti-epidemic measures, infections associated with the provision of medical care, nosocomial infections.