Central Reorganization Research Articles

The legal status and activities of the authorities of the Ukrainian People’s Republic in exile (end of 1920 – August 22, 1992): historical and legal aspects

A historical and legal study of the legal status and activities of the authorities of the Ukrainian People’s Republic (hereinafter - the UPR) in exile (late 1920 – August 22, 1992). It is concluded that, since at the end of 1920 the authorities of the UPR lost influence on the population as a result of the establishment of Soviet power in most of the Ukrainian territories and the UPR actually ceased to exist, which was formally fixed by a peace treaty between the Polish-Lithuanian Commonwealth and Soviet Russia on March 18, 1921. in Riga, the UNR authorities lost their state status and acquired public status. The content adopted by the Council of People’s Ministers and approved by the Chairman of the Directory on January 9, 1921 was analyzed. a normative act entitled “Law on the Council of the Republic,” in which the Council of the Republic was defined as “a temporary supreme authority of the people, which has full power.” The authorities of the UPR imitated state activity: the Council of the Republic – as legislative, the Council of People’s Ministers - as executive authority, the Head of the Directory – as the head of the UPR. After the termination of the existence of the Council of the Republic in August 1921 the functions of the UNR authorities in exile were carried out by the Head of the Directory and the Council of People’s Ministers. The content of the “Temporary Law on the Reorganization of the State Center of the UNR in Exile” of June 10, 1948, which established the competence of the constituent parts of the State Center of the UNR: President, Vice-President, Government, Ukrainian National Council, was studied. Based on the analysis of the content of this normative act, it was concluded that the State Center of the UPR in exile formally had the status of a public organization, but pretended to be a state authority and imitated state functions. According to this document, the Ukrainian National Council performs “the functions of a temporary legislative representation.” The relationship between the constituent parts of the State Center of the UPR in exile had to be revealed in the rule-making process and in the formation of the Government. The political responsibility of the Government to the Ukrainian National Council and the President of the UPR was envisaged. The Government’s accountability to the Ukrainian National Council and control over the UNR President were established. The UNR President was vested with the right to dissolve the Ukrainian National Council at the suggestion of the Government. The authorities formed on the basis of this normative act had the status of public and performed functions in international, normative, political, scientific and other spheres.

A Study on the Performance of Mergers and Acquisitions in the Context of State-Owned Enterprise Reform: The Case of Ansteel and Benxi Steel

The State-owned Assets Supervision and Administration Commission emphasizes that promoting the reorganization of state-owned enterprises (SOEs) can focus their advantageous resources, which plays a positive role in addressing issues such as the uneven distribution of state-owned capital, inefficient resource allocation, and homogenized development. This paper, set against the backdrop of SOE reform and central enterprise reorganization, uses the merger and reorganization event of Ansteel Group and Benxi Steel Group as a case study to investigate how central enterprise reorganization can improve the performance of central enterprises, based on the theory of synergistic effects. The study finds that under the theory of synergistic effects, after the reorganization of Ansteel Group and Benxi Steel Group, the operational, financial, and managerial synergistic effects of Ansteel Group continue to be realized, thereby enhancing the performance level of Ansteel Group. This paper aims to demonstrate the improvement of enterprise performance through central enterprise reorganization and calls on other central enterprises to actively respond to the national requirements for mergers and reorganizations, offering suggestions for subsequent reorganizations of central enterprises.

Effect of ultrasound-guided injection of botulinum toxin type A into shoulder joint cavity on shoulder pain in poststroke patients: study protocol for a randomized controlled trial

BackgroundHemiplegic shoulder pain (HSP) is a common complication after stroke. It severely affects the recovery of upper limb motor function. Early shoulder pain in hemiplegic patients is mainly neuropathic caused by central nerve injury or neuroplasticity. Commonly used corticosteroid injections in the shoulder joint can reduce shoulder pain; however, the side effects also include soft tissue degeneration or increased tendon fragility, and the long-term effects remain controversial. Botulinum toxin injections are relatively new and are thought to block the transmission of pain receptors in the shoulder joint cavity and inhibit the production of neuropathogenic substances to reduce neurogenic inflammation. Some studies suggest that the shoulder pain of hemiplegia after stroke is caused by changes in the central system related to shoulder joint pain, and persistent pain may induce the reorganization of the cortical sensory center or motor center. However, there is no conclusive evidence as to whether or not the amelioration of pain by botulinum toxin affects brain function. In previous studies of botulinum toxin versus glucocorticoids (triamcinolone acetonide injection) in the treatment of shoulder pain, there is a lack of observation of differences in changes in brain function. As the content of previous assessments of pain improvement was predominantly subjective, objective quantitative assessment indicators were lacking. Functional near-infrared imaging (fNIRS) can remedy this problem.MethodsThis study protocol is designed for a double-blind, randomized controlled clinical trial of patients with post-stroke HSP without biceps longus tenosynovitis or acromion bursitis. Seventy-eight patients will be randomly assigned to either the botulinum toxin type A or glucocorticoid group. At baseline, patients in each group will receive shoulder cavity injections of either botulinum toxin or glucocorticoids and will be followed for 1 and 4 weeks. The primary outcome is change in shoulder pain on the visual analog scale (VAS). The secondary outcome is the assessment of changes in oxyhemoglobin levels in the corresponding brain regions by fNIRS imaging, shoulder flexion, external rotation range of motion, upper extremity Fugl-Meyer, and modified Ashworth score.DiscussionUltrasound-guided botulinum toxin type A shoulder joint cavity injections may provide evidence of pain improvement in patients with HSP. The results of this trial are also help to analyze the correlation between changes in shoulder pain and changes in cerebral hemodynamics and shoulder joint motor function.Trial registrationChinese clinical Trial Registry, ChiCTR2300070132. Registered 03 April 2023, https://www.chictr.org.cn/showproj.html?proj=193722.

Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord.

JOURNAL/nrgr/04.03/01300535-202507000-00030/figure1/v/2024-09-09T124005Z/r/image-tiff Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions; behavioral recovery is typically poor. We used a plasmalemmal fusogen, polyethylene glycol (PEG), to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic nerves. We have previously reported that sciatic nerve axons repaired by PEG-fusion do not undergo Wallerian degeneration, and PEG-fused animals exhibit rapid (within 2-6 weeks) and extensive locomotor recovery. Furthermore, our previous report showed that PEG-fusion of severed sciatic motor axons was non-specific, i.e., spinal motoneurons in PEG-fused animals were found to project to appropriate as well as inappropriate target muscles. In this study, we examined the consequences of PEG-fusion for sensory axons of the sciatic nerve. Young adult male and female rats (Sprague-Dawley) received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without (Negative Control) the application of PEG. Compound action potentials recorded immediately after PEG-fusion repair confirmed conduction across the injury site. The success of PEG-fusion was confirmed through Sciatic Functional Index testing with PEG-fused animals showing improvement in locomotor function beginning at 35 days postoperatively. At 2-42 days postoperatively, we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish peroxidase. PEG-fusion repair reestablished axonal continuity. Compared to unoperated animals, labeled sensory afferents ipsilateral to the injury in PEG-fused animals were found in the appropriate area of the dorsal horn, as well as inappropriate mediolateral and rostrocaudal areas. Unexpectedly, despite having intact peripheral nerves, similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repair. This central reorganization may contribute to the improved behavioral recovery seen after PEG-fusion repair, supporting the use of this novel repair methodology over currently available treatments.

Regenerative Anterior Cruciate Ligament Healing in Youth and Adolescent Athletes: The Emerging Age of Recovery Science.

Anterior cruciate ligament (ACL) injuries mainly arise from non-contact mechanisms during sport performance, with most injuries occurring among youth or adolescent-age athletes, particularly females. The growing popularity of elite-level sport training has increased the total volume, intensity and frequency of exercise and competition loading to levels that may exceed natural healing capacity. Growing evidence suggests that the prevailing mechanism that leads to non-contact ACL injury from sudden mechanical fatigue failure may be accumulated microtrauma. Given the consequences of primary ACL injury on the future health and quality of life of youth and adolescent athletes, the objective of this review is to identify key "recovery science" factors that can help prevent these injuries. Recovery science is any aspect of sports training (type, volume, intensity, frequency), nutrition, and sleep/rest or other therapeutic modalities that may prevent the accumulated microtrauma that precedes non-contact ACL injury from sudden mechanical fatigue failure. This review discusses ACL injury epidemiology, current surgical efficacy, the native ACL vascular network, regional ACL histological complexities such as the entheses and crimp patterns, extracellular matrix remodeling, the concept of causal histogenesis, exercise dosage and ligament metabolism, central nervous system reorganization post-ACL rupture, homeostasis regulation, nutrition, sleep and the autonomic nervous system. Based on this information, now may be a good time to re-think primary ACL injury prevention strategies with greater use of modified sport training, improved active recovery that includes well-planned nutrition, and healthy sleep patterns. The scientific rationale behind the efficacy of regenerative orthobiologics and concomitant therapies for primary ACL injury prevention in youth and adolescent athletes are also discussed.

The impact of the first and the second wave of the COVID-19 pandemic on vascular surgery practice in the leading regional center: a comparative, retrospective study

BackgroundWe conducted an analysis of the vascular surgery regional center reorganization in response to the first and the second wave of the coronavirus disease-2019 (COVID-19) pandemic to see what lessons we learned from the first wave.MethodsThe study included a total of 632 patients admitted to the vascular surgery department in three periods: March–May 2020, October–December 2020, and October–December 2019 as a control period.ResultsIn the pandemic periods the number of admitted patients decreased in relation to the control period. There was a reduction in performed procedures. We observed an increase in the ratio of less invasive procedures. There was a significant decline in hospitalization time in comparison to the control period.ConclusionsThe reduction of scheduled admissions and procedures affected vascular centers all over the world. Minimally invasive procedures were more willingly performed to shorten the hospitalization time and reduce the patient's exposure to hospital infection. It allowed us to treat more patients during the second wave. Nevertheless, an increased number of vascular patients should be expected in the future, which will result from the failure to perform elective procedures during the pandemic.

EMG Testing throughout behavioral recovery after rat sciatic nerve crush injury results in exuberant motoneuron dendritic hypertrophy.

Peripheral nerve injury (PNI) is the most common type of nerve trauma yet, while injured motoneurons exhibit a robust capacity for regeneration, behavioral recovery is protracted and typically poor. Neurotherapeutic approaches to PNI and repair have primarily focused on the enhancement of axonal regeneration, in terms of rate, axonal sprouting, and reconnection connectivity. Both electrical stimulation (ES) and treatment with androgens [e.g., testosterone propionate (TP)] have been demonstrated to enhance axonal sprouting, regeneration rate and functional recovery following PNI. To date, very little work has been done to examine the effects of ES and/or TP on dendritic morphology and organization within the spinal cord after PNI. The objective of the current study was to examine the impact of treatment with TP and ES, alone or in combination, on the dendritic arbor of spinal motoneurons after target disconnection via sciatic nerve crush injury in the rat. Rats received a crush injury to the sciatic nerve. Following injury, some animals received either (1) no further treatment beyond implantation with empty Silastic capsules, (2) electrical nerve stimulation immediately after injury, (3) implantation with Silastic capsules filled with TP, or (4) electrical nerve stimulation immediately after injury as well as implantation with TP. All of these groups of axotomized animals also received bi-weekly electromyography (EMG) testing. Additional groups of intact untreated animals as well as a group of injured animals who received no further treatment or EMG testing were also included. Eight weeks after injury, motoneurons innervating the anterior tibialis muscle were labeled with cholera toxin-conjugated horseradish peroxidase, and dendritic arbors were reconstructed in three dimensions. After nerve crush and ES and/or TP treatment, motoneurons innervating the anterior tibialis underwent marked dendritic hypertrophy. Surprisingly, this dendritic hypertrophy occurred in all animals receiving repeated bi-weekly EMG testing, regardless of treatment. When the EMG testing was eliminated, the dendritic arbor extent and distribution after nerve crush in the treated groups did not significantly differ from intact untreated animals. The ability of repeated EMG testing to so dramatically affect central plasticity following a peripheral nerve injury was unexpected. It was also unexpected that gonadal steroid hormones and/or ES, two neurotherapeutic approaches with demonstrated molecular/behavioral changes consistent with peripheral improvements in axonal repair and target reconnection, do not appear to impact central plasticity in a similar manner. The significance of peripheral EMG testing and resulting central plasticity reorganization remains to be determined.

Objective Neurophysiological Indices for the Assessment of Chronic Tinnitus Based on EEG Microstate Parameters.

Chronic tinnitus is highly prevalent but lacks precise diagnostic or effective therapeutic standards. Its onset and treatment mechanisms remain unclear, and there is a shortage of objective assessment methods. We aim to identify abnormal neural activity and reorganization in tinnitus patients and reveal potential neurophysiological markers for objectively evaluating tinnitus. By way of analyzing EEG microstates, comparing metrics under three resting states (OE, CE, and OECEm) between tinnitus sufferers and controls, and correlating them with tinnitus symptoms. This study reflected specific changes in the EEG microstates of tinnitus patients across multiple resting states, as well as inconsistent correlations with tinnitus symptoms. Microstate parameters were significantly different when patients were in OE and CE states. Specifically, the occurrence of Microstate A and the transition probabilities (TP) from other Microstates to A increased significantly, particularly in the CE state (32-37%, p ≤ 0.05 ); and both correlated positively with the tinnitus intensity. Nevertheless, under the OECEm state, increases were mainly observed in the duration, coverage, and occurrence of Microstate B (15-47%, ), which negatively correlated with intensity ( [Formula: see text]-0.513, ). Additionally, TPx between Microstates C and D were significantly reduced and positively correlated with HDAS levels ( [Formula: see text] 0.548, ). Furthermore, parameters of Microstate D also correlated with THI grades ( [Formula: see text]-0.576, ). The findings of this study could offer compelling evidence for central neural reorganization associated with chronic tinnitus. EEG microstate parameters that correlate with tinnitus symptoms could serve as neurophysiological markers, contributing to future research on the objective assessment of tinnitus.

Functional near-infrared spectroscopy in non-invasive neuromodulation.

Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks, which have been widely applied in the field of central neurological diseases, such as stroke, Parkinson's disease, and mental disorders. Although significant advances have been made in neuromodulation technologies, the identification of optimal neurostimulation parameters including the cortical target, duration, and inhibition or excitation pattern is still limited due to the lack of guidance for neural circuits. Moreover, the neural mechanism underlying neuromodulation for improved behavioral performance remains poorly understood. Recently, advancements in neuroimaging have provided insight into neuromodulation techniques. Functional near-infrared spectroscopy, as a novel non-invasive optical brain imaging method, can detect brain activity by measuring cerebral hemodynamics with the advantages of portability, high motion tolerance, and anti-electromagnetic interference. Coupling functional near-infrared spectroscopy with neuromodulation technologies offers an opportunity to monitor the cortical response, provide real-time feedback, and establish a closed-loop strategy integrating evaluation, feedback, and intervention for neurostimulation, which provides a theoretical basis for development of individualized precise neurorehabilitation. We aimed to summarize the advantages of functional near-infrared spectroscopy and provide an overview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation, transcranial electrical stimulation, neurofeedback, and brain-computer interfaces. Furthermore, the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are summarized. In conclusion, functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central neural reorganization to achieve better functional recovery from central nervous system diseases.

Reorganization of the SUEM-118 Operations Center in Verona during the "first wave" of the COVID-19 pandemic: data analysis

Reorganization of the SUEM-118 Operations Center in Verona during the "first wave" of the COVID-19 pandemic: data analysis

중국 반독점법 2022년 개정법의 실체법적 개정사항

On June 24, 2022, at the 35th meeting of the Standing Committee of the 13th National People's Congress, the amendment to the Anti-monopoly Law of the People's Republic of China was passed. It was decided to go into effect on August 1st. This is the first amendment to China's Anti-monopoly Law since its implementation in 2008. A new purpose was proposed in maintaining an orderly market system. This amendment adds innovation encouragement to the legislative purpose of the Anti-monopoly Law, in line with Xi Jinping's leadership's keynote on state affairs, which has emphasized technological innovation. It is specified in this law that it is responsible. In the 2018 central organizational reorganization, the newly established State Administration for Market Regulation, the Anti-monopoly Bureau, which was in charge of anti-monopoly work that had been distributed among the Ministry of Commerce, Development and Development, and the General Administration of Industry and Trade, was separated into a vice-ministerial level organization and upgraded to the State Anti-monopoly Bureau. The amendment bans monopoly, exclusion, and competition restrictions that abuse administrative power, and strengthens the level of punishment, such as significantly increasing the level of fines and linking antitrust penalties with credit records. Clarify the criteria for screening and classifying managers to strengthen screening of managers related to the national economy and livelihood, while introducing a safe harbor rule to exclude managers from sanctions if they prove that their market share is lower than the anti-monopoly standards made with In addition, managers who provide “substantial help” in concluding and implementing monopoly agreements are also subject to sanctions. The amendment is a review of China's anti-monopoly law enforcement over the past 10 years during the deliberation of the revision of the Chinese anti-monopoly law, and can be seen as a summary of legal practice experience. This is a demand inherent in the development of China's socialist market economy, and can help meet the objective demand of the new development pattern. It is conducive to introducing Chinese anti-monopoly law supervision and strengthening anti-monopoly law enforcement, which will be scientifically and objectively conducive.

Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas.

Tinnitus is closely associated with cognition functioning. In order to clarify the central reorganization of tinnitus in patients with vestibular schwannoma (VS), this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and their correlations with tinnitus features in VS patients. Clinical and EEG data were collected from 98 VS patients, including 76 with tinnitus and 22 without tinnitus. Microstates were clustered into four categories. Our EEG microstate analysis revealed that VS patients with tinnitus exhibited an increased frequency of microstate C compared to those without tinnitus. Furthermore, correlation analysis demonstrated that the Tinnitus Handicap Inventory (THI) score was negatively associated with the duration of microstate A and positively associated with the frequency of microstate C. These findings suggest that the time series and syntax characteristics of EEG microstates differ significantly between VS patients with and without tinnitus, potentially reflecting abnormal allocation of neural resources and transition of functional brain activity. Our results provide a foundation for developing diverse treatments for tinnitus in VS patients.

Vestibular loss disrupts visual reactivity in the alpha EEG rhythm

The alpha rhythm is a dominant electroencephalographic oscillation relevant to sensory-motor and cognitive function. Alpha oscillations are reactive, being for example enhanced by eye closure, and suppressed following eye opening. The determinants of inter-individual variability in reactivity in the alpha rhythm (e.g. changes with amplitude following eye closure) are not fully understood despite the physiological and clinical applicability of this phenomenon, as indicated by the fact that ageing and neurodegeneration reduce reactivity. Strong interactions between visual and vestibular systems raise the theoretical possibility that the vestibular system plays a role in alpha reactivity. To test this hypothesis, we applied electroencephalography in sitting and standing postures in 15 participants with reduced vestibular function (bilateral vestibulopathy, median age = 70 years, interquartile range = 51–77 years) and 15 age-matched controls. We found participants with reduced vestibular function showed less enhancement of alpha electroencephalography power on eye closure in frontoparietal areas, compared to controls. In participants with reduced vestibular function, video head impulse test gain – as a measure of residual vestibulo-ocular reflex function – correlated with reactivity in alpha power across most of the head. Greater reliance on visual input for spatial orientation (‘visual dependence’, measured with the rod-and-disc test) correlated with less alpha enhancement on eye closure only in participants with reduced vestibular function, and this was partially moderated by video head impulse test gain. Our results demonstrate for the first time that vestibular function influences alpha reactivity. The results are partly explained by the lack of ascending peripheral vestibular input but also by central reorganisation of processing relevant to visuo-vestibular judgements.

Diagnosis of complex regional pain syndrome

Complex regional pain syndrome (CRPS) is a chronic regional pain disorder that most frequently affects the limbs. It is characterized by hyperalgesia, allodynia, edema, motor disturbance, and vasomotor instability, and typically occurs following surgery or trauma. In type-I CRPS there is no confirmed nerve injury, while peripheral nerve injury is present in type-II CRPS. The multifactorial pathophysiological etiology of CRPS includes inflammation, autoimmune responses, abnormal cytokine production, autonomic dysfunction, altered blood flow, psychological factors, and central cortical reorganization. There are no specific laboratory diagnostic tools for CRPS, and so it is diagnosed clinically. The Budapest criteria are currently the most-accepted diagnostic criteria.

Aberrant sensorimotor coupling and movement planning in complex regional pain syndrome.

Complex regional pain syndrome (CRPS) is characterized by inflammation and a failure of multimodal signal integration in the central nervous system (CNS). Central nervous system reorganization might account for sensory deficits, pain, and motor symptoms in CRPS, but it is not clear how motor control is affected by CNS mechanisms. The present study characterized the motor performance and related cortical activity of 16 CRPS patients and 16 control participants during the planning of visually guided unimanual grips, in patients with either the unaffected left or the affected right hand, and investigated resting-state sensorimotor coupling in MRI. Patients started isometric movements further in advance of the "go" cue and earlier than control participants. Even when accounting for this different timing, results showed side-independent overactivation in planning-related sensorimotor regions in CRPS during manual grips and increased functional coupling between those regions at rest. Fear of movement or individual pain scores contributed only marginally to the observed effects. The study suggests that changes in planning-related sensorimotor CNS regions may explain difficulties with force exertion and motor control in CRPS.Perspective : Functional changes in motor planning-related brain regions might indicate that feedback-enhanced functional motor training may be effective for CRPS rehabilitation.

Molecular Designs to Achieve High-Rate and Ultra-Stable Organic Electrode Materials for Future Sustainable Batteries

Organic electrode materials (OEMs) are recently drawing much attention as a promising alternative to conventional transition metal oxide electrodes due to their many advantages, including abundance, sustainability, bio-compatibility, low cost, and easy tunability.[1] Most importantly, the flexible nature of organic materials due to loosely packed intermolecular structures allows fast diffusion for charge-carrying ions, which is essential for the high-rate performance of electrode materials. However, in practice, most OEMs still suffer from slow rate capability and low capacity utilization due to their electrically insulating nature. In a typical battery, the rate capability of an electrode is determined by the kinetic factors for the following three steps during the charge/discharge processes: i) redox reaction of active materials, ii) electron conduction through the active materials and the conductive carbon additives to the current collector, iii) and ion diffusion inside the active materials.[2] Previously, most studies have focused on improving the electrical conductivity of OEMs to achieve high-rate capability; however, such attempts typically sacrificed their specific capacity and/or cycle stability. Here, we present novel molecular design strategies to achieve high-rate capability of OEMs without deterioration of their specific capacity and cycle stability. First, we recently proposed that a small structural reorganization of the redox center during the redox reaction would be a key to achieving fast rate capability in OEMs for the first time.[3] We revealed that a novel p-type redox center phenoxazine (PXZ) had faster redox kinetics than its widely used analogue phenothiazine (PTZ) due to negligibly smaller structural changes, which was evidenced by theoretical calculations using the density functional theory (DFT) method and experimental measurements. In practical coin-cells, such low reorganization of the PXZ center led to high-rate performance (73% capacity retention at 20C) of a PXZ trimer electrode material (3PXZ) with a narrow voltage plateau at 3.7 V vs. Li/Li+. Then, in this presentation, we introduce our new OEMs bearing n-type redox centers with low reorganization energy, including tetrazine (Tz)[4-6] and thieno-isoindigo (TIIG).[7] The new OEMs showed superior rate capability (> 50% capacity retention at 50C) and high cycle stability (> 80% capacity retention after 500 cycles). Finally, we present novel OEMs spontaneously forming various nanostructures via self-assembly after fabricating electrodes.[8] The high surface area of the nanostructured OEMs provided fast electron transfer from the insulating active materials to the conductive carbons and easy access of the charge-carrying ions to the active materials, leading to ultrafast rate performance (> 50% capacity retention at 100C) even with high active content more than 70 wt% in the electrode.

Comparing the effectiveness of central nervous system reorganization method (Domain-Delacato) and neurofeedback on improving reading skills of dyslexic children

Comparing the effectiveness of central nervous system reorganization method (Domain-Delacato) and neurofeedback on improving reading skills of dyslexic children

Comparing the effectiveness of central nervous system reorganization method (Domain-Delacato) and neurofeedback on improving reading skills of dyslexic children

The present study was conducted with the aim of comparing the effectiveness of central nervous system reorganization method (Domain-Delacato) and neurofeedback on improving the reading skills of dyslexic children. The present study was a semi-experimental study with a pre-test and post-test design with a control group. The statistical population of the present study was made up of all students aged 10 to 13 with reading disorders who referred to educational and clinical centers in Qochan city in the academic year of 2018-2019; And the research sample included 45 subjects who were selected by available sampling method and were randomly placed in three experimental groups 1 (15 people), experimental 2 (15 people) and control (15 people). To collect data, the reading and dyslexia test of Karmi Nouri and Moradi (2008) was used. For the statistical analysis of the data, analysis of covariance was used with the help of SPSS software. The results showed that the method of reorganizing the central nervous system (Domain-Delacato) and neurofeedback compared to the control group improved the scores of reading skills and reading components of words, word chain, rhyme test, naming pictures, understanding text, understanding words, eliminating sounds, Pseudo-words and non-words, letter signs and categorized signs (P<0.05). The neurofeedback group has been more effective in increasing reading skills and components of word reading, word chain, rhyme test, naming pictures, understanding words, pseudowords and nonwords, and category signs than the central nervous system reorganization method (Domain-Delacato). Also, there is no statistically significant difference between the effectiveness of the central nervous system reorganization method (Domain-Delacato) compared to neurofeedback in increasing the scores of text understanding, removing sounds, letter signs (P>0.05). Therefore, the method of reorganizing the central nervous system (Domain-Delacato) and neurofeedback is an effective method in improving the reading skills of dyslexic children

Moebius syndrome - improving outcome with combined state-of-the-art surgical and rehabilitation treatments

Moebius Syndrome (MBS) is a rare disorder, characterized by congenital, non-progressive facial palsy and other cranial and limb defects. A typical “mask-like” appearance, drooling, and indistinct speech comprise the dominant features. Treatment focuses on correcting deformities and enhancing functionality. Surgical free functional muscle transfer (FFMT) is the gold standard for facial reanimation. A comprehensive rehabilitation program addressing motor, cognitive, and social impairment is paramount, despite the scarcity of knowledge regarding MBS rehabilitation, especially concerning central nervous system reorganization. A six-year-old boy with MBS received treatment in our Department since the age of four months, including speech, physical, and occupational therapy. Recently, he underwent facial reanimation surgery. The authors believe that rehabilitation improved the patient’s outcome by enhancing cortical representation before and neuroplasticity after surgery. Coordination of both interventions seems pivotal to fully address MBS.

Reorganização do trabalho do NASF-AB no enfrentamento da pandemia COVID- 19

Objetivo: relatar a experiência das residentes do Programa de residência em Saúde da Família e Comunidade na reorganização do Núcleo de Apoio à Saúde da Família (NASF) em um território, para o enfrentamento da Pandemia de COVID-19. Método: relato de experiência. Informações coletadas em fontes oficiais e registros das vivências dos autores. Resultados: as estratégias adotadas durante a pandemia foram: teleatendimento, telemonitoramento, produção de materiais educativos, novo fluxograma de atendimento, porta de entrada de sintomáticos, suporte as equipes e testagem rápida. Conclusão: adaptação rápida e consistente para apoiar a Estratégia Saúde da Família no cuidado a população.